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Santiago

$360+ Cheap flights from Houston to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — SCL
Jun 5 — Jun 121
Fri 6/5
Fri 6/12
1 adult, Economy
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Cheap flight deals from Houston to Santiago

Cheapest flights from Houston to Santiago
Explore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:37 pm
IAH
-
SCL
1 stop22h 08m
Multiple Airlines
Tue 8/113:35 am
SCL
-
IAH
2 stops29h 19m
Multiple Airlines
Deal found 5/6$825
This eDestinos deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:29 pm
IAH
-
SCL
2 stops56h 14m
Multiple Airlines
Mon 6/18:20 pm
SCL
-
IAH
2 stops40h 22m
Multiple Airlines
Deal found 5/1$830
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:37 pm
IAH
-
SCL
1 stop22h 08m
Multiple Airlines
Mon 8/105:00 am
SCL
-
IAH
2 stops27h 54m
Multiple Airlines
Deal found 5/6$837
This Lucky2Go deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lucky2Go is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:17 pm
IAH
-
SCL
2 stops31h 13m
Multiple Airlines
Wed 6/248:20 pm
SCL
-
IAH
2 stops36h 42m
Multiple Airlines
Deal found 5/5$839
This eDestinos deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:44 pm
IAH
-
SCL
2 stops40h 51m
Multiple Airlines
Tue 6/912:40 am
SCL
-
IAH
2 stops32h 22m
Multiple Airlines
Deal found 5/3$845
This Mytrip deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:55 pm
IAH
-
SCL
3 stops28h 40m
Multiple Airlines
Sun 6/79:30 pm
SCL
-
IAH
2 stops22h 55m
Multiple Airlines
Deal found 5/5$867
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:37 pm
IAH
-
SCL
1 stop31h 58m
Multiple Airlines
Tue 8/113:35 am
SCL
-
IAH
2 stops29h 19m
Multiple Airlines
Deal found 5/6$870
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:37 pm
IAH
-
SCL
1 stop22h 08m
Multiple Airlines
Sun 8/95:00 am
SCL
-
IAH
2 stops27h 54m
Multiple Airlines
Deal found 5/6$880
This Air Canada deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:55 am
IAH
-
SCL
1 stop20h 20m
Air Canada
Thu 12/38:55 pm
SCL
-
IAH
1 stop17h 14m
Air Canada
Deal found 5/1$881
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:37 pm
IAH
-
SCL
1 stop31h 58m
Multiple Airlines
Mon 8/105:00 am
SCL
-
IAH
2 stops27h 54m
Multiple Airlines
Deal found 5/6$882
This Air Canada deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:10 am
IAH
-
SCL
1 stop25h 05m
Air Canada
Thu 11/268:55 pm
SCL
-
IAH
1 stop27h 49m
Air Canada
Deal found 5/1$886
This KAYAK deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:14 pm
HOU
-
SCL
1 stop13h 01m
LATAM Airlines
Tue 8/48:40 pm
SCL
-
HOU
1 stop16h 36m
LATAM Airlines
Deal found 5/6$1,127

Find flight deals from Houston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 6, 2026.

Round-trip from

$825
(Kiwi.com)

One-way from

$360
(Kiwi.com)

Popular in

April

Cheapest in

May

Average price

$847
From Houston to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Houston to Santiago Arturo Merino Benitez
Search Deals
High demand for flights, 3% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in May 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sat 6/6

7:33 pm-1:35 pm

2 stops41h 02m

Santiago Arturo Merino Benitez

Sun 7/26

10:30 am-7:54 am

1 stop22h 24m

$1,015

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sat 6/13

8:55 pm-3:55 am

3 stops30h 00m

Santiago Arturo Merino Benitez

Sat 8/8

3:20 pm-9:31 pm

3 stops31h 11m

$1,042

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 9/24

5:45 pm-2:05 pm

2 stops18h 20m

Santiago Arturo Merino Benitez

Fri 9/25

4:20 pm-1:17 pm

2 stops22h 57m

$1,087

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Mon 8/3

5:35 pm-7:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Tue 8/11

8:40 pm-4:23 pm

1 stop20h 43m

$1,135

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Mon 8/3

10:50 am-6:00 am

2 stops18h 10m

Santiago Arturo Merino Benitez

Wed 8/12

8:40 pm-12:16 pm

1 stop16h 36m

$1,135

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 6/25

10:09 am-6:00 am

2 stops18h 51m

Santiago Arturo Merino Benitez

Wed 7/8

11:05 pm-9:51 pm

2 stops23h 46m

$1,135

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 7/28

10:40 am-7:15 am

1 stop19h 35m

Santiago Arturo Merino Benitez

Thu 8/6

8:40 pm-9:50 am

1 stop14h 10m

$1,135

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 6/25

4:20 pm-7:15 am

1 stop13h 55m

Santiago Arturo Merino Benitez

Wed 7/8

8:40 pm-5:42 pm

1 stop22h 02m

$1,135

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Wed 7/8

5:14 pm-7:15 am

1 stop13h 01m

Santiago Arturo Merino Benitez

Sun 7/19

11:05 pm-9:51 pm

2 stops23h 46m

$1,141

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Wed 7/8

12:09 pm-7:15 am

1 stop18h 06m

Santiago Arturo Merino Benitez

Sun 7/19

11:05 pm-5:42 pm

2 stops19h 37m

$1,141

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/1

Showing 1-10 of 33 resultsSorted by cheapest first
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Best time to book a flight from Houston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago

What is the cheapest month to book a flight from Houston to Santiago?

Currently, September is the cheapest month in which you can book a flight from Houston to Santiago (average of $96). Flying from Houston to Santiago in February is currently the most expensive (average of $949). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Houston to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 6, 2026.
See what other customers who have flown with LATAM Airlines,United Airlines, andAmerican Airlines from Houston to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,919 reviews

Entertainment

7.0

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
LATAM Airlines
7.4
Good
1,919 reviews
LATAM Airlines
7.4
Good
1,919 reviews

Entertainment

7.0

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
United Airlines
7.4
Good
9,690 reviews
LATAM Airlines
7.4
Good
1,919 reviews

Entertainment

7.0

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
American Airlines
7.1
Good
11,669 reviews
LATAM Airlines
7.4
Good
1,919 reviews

Entertainment

7.0

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
Avianca
6.5
Okay
2,522 reviews
LATAM Airlines
7.4
Good
1,919 reviews

Entertainment

7.0

Overall

7.4

Food

6.7

Comfort

7.3

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Houston?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Houston. Booking flights from Houston to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Houston from 4 different airlines.

  • How long is the flight from Houston to Santiago?

    Departing from Houston to Santiago will take you 12h 40m. Houston and Santiago are separated by a distance of 4637 mi.

  • What are the cheapest airlines flying from Houston to Santiago round-trip?

    Cheapflights users have booked flights from Houston to Santiago round-trip from $516. Other airlines that can offer you cheap pricing are LATAM Airlines, from $949, and United Airlines, from $949. Users have found that Avianca is 57% cheaper than the other options available to this destination.

  • Can I find deals for flights from Houston to Santiago that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago.

  • Can I find deals for business class flights from Houston to Santiago?

    Yes. Cheapflights offers flight deals from Houston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago?

    Currently, September is the cheapest month in which you can book a flight from Houston to Santiago (average of $96). Flying from Houston to Santiago in February is currently the most expensive (average of $949). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Houston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Austin to Santiago flights
Dallas/Fort Worth to Santiago flights
George Bush Intcntl to Santiago flights
San Antonio to Santiago flights

Top 4 airlines flying from Houston to Santiago

Discover the top 4 airlines that operate flights from Houston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$516Average$673FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$949Average$1,193FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$949Average$1,225FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$1,005Average$1,659FlexibilityNo cancel feeOn-time71%

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