$295+ Cheap flights from Houston to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — SCL
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Houston to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santiago
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Cheapest flights from Houston to SantiagoExplore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:32 pm -
2 stops29h 03m
Sat 12/511:10 pm -
1 stop36h 10m
Deal found 9/11![Multiple Airlines logo]()
$783
This Air Canada deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:50 am -
1 stop16h 00m
Tue 12/158:25 am -
2 stops29h 28m
Deal found 9/14![Air Canada logo]()
$786
This Air Canada deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:20 pm -
2 stops33h 30m
Wed 12/168:25 am -
2 stops29h 28m
Deal found 9/11![Air Canada logo]()
$806
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:21 pm -
2 stops54h 01m
Wed 10/2111:55 pm -
1 stop15h 20m
Deal found 9/15![Multiple Airlines logo]()
$809
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:32 pm -
2 stops30h 04m
Sat 11/711:10 pm -
1 stop17h 37m
Deal found 9/14![Multiple Airlines logo]()
$855
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:21 pm -
2 stops29h 18m
Sun 10/2510:15 am -
1 stop29h 00m
Deal found 9/10![Multiple Airlines logo]()
$856
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:27 pm -
2 stops36h 11m
Tue 11/1711:25 pm -
1 stop35h 54m
Deal found 9/11![Multiple Airlines logo]()
$863
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:32 pm -
2 stops37h 06m
Wed 11/1811:25 pm -
1 stop35h 54m
Deal found 9/15![Multiple Airlines logo]()
$869
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:01 pm -
2 stops23h 12m
Mon 12/149:55 pm -
1 stop22h 23m
Deal found 9/14![Multiple Airlines logo]()
$899
This LATAM Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:41 am -
2 stops15h 39m
Tue 12/157:40 am -
2 stops18h 52m
Deal found 9/15![LATAM Airlines logo]()
$1,134
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:41 am -
1 stop17h 59m
Tue 12/159:50 pm -
1 stop21h 40m
Deal found 9/15![Delta logo]()
$1,135
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:08 am -
2 stops20h 27m
Mon 12/2111:00 pm -
1 stop22h 00m
Deal found 9/15![Delta logo]()
$1,140
Best flights from Houston to SantiagoDiscover carefully curated flight deals from Houston to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Houston to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:32 pm -
2 stops29h 03m
Mon 11/1611:25 pm -
1 stop35h 54m
Deal found 9/12![Multiple Airlines logo]()
$912
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:30 pm -
Nonstop9h 20m
Tue 12/1510:45 pm -
Nonstop9h 40m
Deal found 9/12![United Airlines logo]()
$1,113
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:03 pm -
2 stops23h 57m
Wed 11/1811:10 pm -
2 stops18h 58m
Deal found 9/15![Delta logo]()
$1,123
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:20 pm -
1 stop16h 25m
Mon 11/1610:30 pm -
1 stop15h 59m
Deal found 9/13![American Airlines logo]()
$1,144
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:45 pm -
2 stops19h 30m
Sun 10/181:30 am -
2 stops16h 40m
Deal found 9/11![Avianca logo]()
$1,173
This LATAM Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:35 am -
1 stop23h 05m
Thu 12/3111:00 pm -
1 stop17h 34m
Deal found 9/13![LATAM Airlines logo]()
$1,196
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:30 pm -
Nonstop9h 20m
Wed 12/1610:45 pm -
Nonstop9h 40m
Deal found 9/14![United Airlines logo]()
$1,121
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:41 am -
1 stop17h 59m
Tue 12/159:50 pm -
1 stop21h 40m
Deal found 9/15![Delta logo]()
$1,135
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/215:05 pm -
1 stop11h 40m
Sun 1/3111:45 pm -
1 stop12h 42m
Deal found 9/12![American Airlines logo]()
$1,155
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:35 am -
1 stop23h 05m
Mon 11/2311:55 pm -
1 stop17h 45m
Deal found 9/10![Delta logo]()
$1,135
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:20 pm -
1 stop16h 25m
Sat 12/511:45 pm -
1 stop16h 46m
Deal found 9/11![American Airlines logo]()
$1,195
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:08 am -
2 stops20h 27m
Mon 12/2110:15 am -
2 stops26h 38m
Deal found 9/15![Delta logo]()
$1,140
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:35 pm -
2 stops18h 25m
Thu 1/218:13 am -
2 stops28h 36m
Deal found 9/12![Delta logo]()
$1,155
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:09 am -
2 stops22h 21m
Mon 11/1611:10 pm -
1 stop13h 22m
Deal found 9/13![Delta logo]()
$1,155
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
2 stops30h 00m
Sun 1/318:13 am -
2 stops28h 36m
Deal found 9/15![Delta logo]()
$1,175
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:09 am -
2 stops22h 21m
Mon 11/168:40 am -
2 stops27h 52m
Deal found 9/12![Delta logo]()
$1,195
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:27 pm -
2 stops18h 33m
Sun 12/208:25 pm -
2 stops24h 35m
Deal found 9/14![Delta logo]()
$1,195
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1110:38 am -
1 stop18h 02m
Fri 1/228:25 pm -
2 stops23h 05m
Deal found 9/14![Delta logo]()
$1,195
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:05 am -
2 stops20h 25m
Sun 11/298:13 am -
2 stops18h 46m
Deal found 9/14![Delta logo]()
$1,215
Last-minute flights from Houston to SantiagoDiscover last-minute flight deals from Houston to Santiago. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santiago. Data last updated September 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:10 pm -
2 stops46h 29m
Mon 9/289:30 am -
2 stops30h 03m
Deal found 9/15![Multiple Airlines logo]()
$986
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:10 pm -
2 stops26h 46m
Wed 9/3011:55 pm -
1 stop15h 38m
Deal found 9/14![Multiple Airlines logo]()
$952
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:18 pm -
2 stops37h 08m
Thu 10/1511:55 pm -
1 stop15h 20m
Deal found 9/12![Multiple Airlines logo]()
$1,049
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:41 am -
2 stops18h 29m
Wed 4/148:35 pm -
2 stops20h 14m
Deal found 9/15![American Airlines logo]()
$1,265
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:28 pm -
1 stop12h 47m
Tue 10/208:40 pm -
1 stop15h 28m
Deal found 9/14![LATAM Airlines logo]()
$1,371
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:09 am -
2 stops21h 41m
Tue 10/208:40 pm -
1 stop15h 28m
Deal found 9/14![Delta logo]()
$1,385
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:21 pm -
2 stops54h 01m
Wed 10/2111:55 pm -
1 stop15h 20m
Deal found 9/15![Multiple Airlines logo]()
$809
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:21 pm -
2 stops29h 18m
Sun 10/2510:15 am -
1 stop29h 00m
Deal found 9/10![Multiple Airlines logo]()
$856
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:21 pm -
2 stops29h 18m
Mon 10/2611:55 pm -
1 stop37h 37m
Deal found 9/10![Multiple Airlines logo]()
$964
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:39 am -
3 stops32h 36m
Mon 11/29:55 pm -
1 stop22h 13m
Deal found 9/11![Multiple Airlines logo]()
$956
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:08 pm -
2 stops16h 27m
Tue 11/310:30 pm -
2 stops21h 02m
Deal found 9/12![American Airlines logo]()
$1,285
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:32 pm -
2 stops30h 04m
Sat 11/711:10 pm -
1 stop17h 37m
Deal found 9/14![Multiple Airlines logo]()
$855
One-way flights from Houston to SantiagoSearch for one-way flight options from Houston to Santiago. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Houston to Santiago. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:05 am -
3 stops44h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:14 pm -
3 stops54h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:12 pm -
3 stops53h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:39 am -
2 stops33h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:39 am -
2 stops33h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:21 pm -
3 stops28h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:39 am -
3 stops48h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:04 pm -
3 stops28h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:59 pm -
3 stops33h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$514
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
3 stops21h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$608
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/46:00 am -
3 stops42h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:44 pm -
3 stops57h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$788
Find flight deals from Houston to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Round-trip from | $783 (Kiwi.com) |
|---|---|
One-way from | $295 (Kiwi.com) |
Popular in | May |
Cheapest in | November |
Average price | $1,135 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Mon 11/16
9:14 pm-6:38 am
3 stops54h 24m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$303
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Wed 11/11
8:21 pm-3:38 am
3 stops28h 17m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$322
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Mon 10/5
9:04 pm-3:56 am
3 stops28h 52m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$346
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Tue 10/13
9:12 pm-3:35 am
3 stops52h 23m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$463
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Sat 10/17
4:55 pm-6:10 am
2 stops35h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$466
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Mon 10/12
2:00 pm-9:55 pm
3 stops53h 55m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$534
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Fri 11/6
2:32 pm-10:35 pm
2 stops29h 03m
Santiago Arturo Merino Benitez
Mon 11/16
11:25 pm-8:19 am
1 stop35h 54m
$912
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Tue 12/1
8:30 pm-8:50 am
Nonstop9h 20m
Santiago Arturo Merino Benitez
Tue 12/15
10:45 pm-5:25 am
Nonstop9h 40m
$1,113
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Wed 12/2
8:30 pm-8:50 am
Nonstop9h 20m
Santiago Arturo Merino Benitez
Wed 12/16
10:45 pm-5:25 am
Nonstop9h 40m
$1,121
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Thu 11/5
12:03 pm-3:00 pm
2 stops23h 57m
Santiago Arturo Merino Benitez
Wed 11/18
11:10 pm-3:08 pm
2 stops18h 58m
$1,123
Showing 1-10 of 35 resultsSorted by cheapest first
Best time to book a flight from Houston to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Houston with our price prediction graph.
HO1-SCL
IAH-SCL
HOU-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santiago
HO1-SCL
IAH-SCL
HOU-SCL
What is the cheapest month to book a flight from Houston to Santiago?
Currently, February is the cheapest month in which you can book a flight from Houston to Santiago (average of $1,124). Flying from Houston to Santiago in May is currently the most expensive (average of $2,231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 15, 2026.
See what other customers who have flown with LATAM Airlines,United Airlines, andAmerican Airlines from Houston to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.0
Comfort
7.3
Boarding
7.5
Food
6.7
Entertainment
7.0
Overall
7.4
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Crew
8.0
Comfort
7.3
Boarding
7.5
Food
6.7
Entertainment
7.0
Overall
7.4
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Crew
8.0
Comfort
7.3
Boarding
7.5
Food
6.7
Entertainment
7.0
Overall
7.4
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Crew
8.0
Comfort
7.3
Boarding
7.5
Food
6.7
Entertainment
7.0
Overall
7.4
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Related info for your journey
Find useful and relevant information for your journey from Houston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santiago flight routes
Alternative routes for Houston to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Houston to Santiago by cabin class
Find flights from Houston to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Houston and Santiago flights
Browse other Houston and Santiago flight options. Last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Top 3 airlines flying from Houston to Santiago
Discover the top 3 airlines that operate flights from Houston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$949 | Average$1,277 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$964 | Average$1,365 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,005 | Average$1,462 | FlexibilityNo cancel fee | On-time71% |