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Santiago

$253+ Cheap flights from Houston to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — SCL
Aug 31 — Sep 71
Mon 8/31
Mon 9/7
1 adult, Economy
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Cheap flight deals from Houston to Santiago

Cheapest flights from Houston to Santiago
Explore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:21 pm
IAH
-
SCL
2 stops32h 25m
Multiple Airlines
Wed 9/1612:35 am
SCL
-
IAH
1 stop14h 58m
Multiple Airlines
Deal found 7/29$635
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:45 pm
IAH
-
SCL
2 stops36h 15m
Multiple Airlines
Tue 8/258:30 am
SCL
-
IAH
2 stops26h 24m
Multiple Airlines
Deal found 7/31$653
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:09 pm
IAH
-
SCL
2 stops32h 47m
Multiple Airlines
Sun 11/811:10 pm
SCL
-
IAH
1 stop13h 50m
Multiple Airlines
Deal found 7/29$656
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:09 pm
IAH
-
SCL
2 stops32h 47m
Multiple Airlines
Sun 11/811:10 pm
SCL
-
IAH
1 stop13h 50m
Multiple Airlines
Deal found 7/29$658
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:09 pm
IAH
-
SCL
2 stops31h 37m
Multiple Airlines
Wed 11/1111:10 pm
SCL
-
IAH
1 stop13h 50m
Multiple Airlines
Deal found 7/29$666
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:09 pm
IAH
-
SCL
2 stops31h 37m
Multiple Airlines
Wed 11/1111:10 pm
SCL
-
IAH
1 stop13h 50m
Multiple Airlines
Deal found 7/29$667
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:39 pm
IAH
-
SCL
2 stops31h 59m
Multiple Airlines
Sun 11/811:10 pm
SCL
-
IAH
1 stop13h 50m
Multiple Airlines
Deal found 7/29$676
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:57 am
IAH
-
SCL
2 stops17h 03m
Multiple Airlines
Sun 8/3012:35 am
SCL
-
IAH
1 stop34h 19m
Multiple Airlines
Deal found 7/29$677
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:45 pm
IAH
-
SCL
2 stops35h 05m
Multiple Airlines
Sun 8/3012:35 am
SCL
-
IAH
1 stop34h 19m
Multiple Airlines
Deal found 7/30$686
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:57 am
IAH
-
SCL
2 stops37h 29m
Multiple Airlines
Fri 8/2811:00 pm
SCL
-
IAH
1 stop13h 53m
Multiple Airlines
Deal found 7/30$687
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:25 pm
IAH
-
SCL
2 stops29h 31m
Multiple Airlines
Mon 10/510:25 am
SCL
-
IAH
1 stop29h 08m
Multiple Airlines
Deal found 7/28$688
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:45 pm
IAH
-
SCL
2 stops36h 15m
Multiple Airlines
Wed 9/211:00 pm
SCL
-
IAH
1 stop34h 44m
Multiple Airlines
Deal found 7/28$692

Find flight deals from Houston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 1, 2026.

Round-trip from

$635
(Kiwi.com)

One-way from

$253
(Kiwi.com)

Popular in

May

Cheapest in

November

Average price

$1,365
From Houston to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Houston to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 40% potential increase in price ($1,129 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 24% potential price decrease ($321 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 11/6

7:47 pm-5:03 am

3 stops30h 16m

Santiago Arturo Merino Benitez

Sun 11/15

4:25 pm-9:39 pm

3 stops32h 14m

$1,130

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Mon 9/21

11:00 am-5:50 am

2 stops16h 50m

Santiago Arturo Merino Benitez

Mon 10/5

8:40 pm-10:08 am

1 stop15h 28m

$1,135

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Wed 10/21

4:59 pm-8:15 am

1 stop13h 16m

Santiago Arturo Merino Benitez

Mon 11/9

11:55 pm-2:32 pm

1 stop17h 37m

$1,135

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 10/22

6:20 pm-3:00 pm

2 stops18h 40m

Santiago Arturo Merino Benitez

Mon 11/9

8:40 am-10:11 pm

2 stops16h 31m

$1,135

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 9/25

2:25 pm-8:15 am

1 stop15h 50m

Santiago Arturo Merino Benitez

Thu 10/8

8:40 pm-10:08 am

1 stop15h 28m

$1,175

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 9/25

4:58 pm-8:15 am

1 stop13h 17m

Santiago Arturo Merino Benitez

Thu 10/8

8:40 pm-10:59 am

1 stop16h 19m

$1,175

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sat 11/21

8:30 pm-8:50 am

Nonstop9h 20m

Santiago Arturo Merino Benitez

Sun 11/29

10:45 pm-5:25 am

Nonstop9h 40m

$1,201
Quickest round-trip

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sat 10/31

8:50 pm-7:50 am

Nonstop9h 00m

Santiago Arturo Merino Benitez

Sat 11/7

10:45 pm-5:05 am

Nonstop9h 20m

$1,201

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 11/6

6:09 am-7:40 am

1 stop22h 31m

Santiago Arturo Merino Benitez

Sun 11/15

8:30 pm-9:30 am

2 stops16h 00m

$1,215

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sun 11/29

7:05 am-6:50 am

1 stop20h 45m

Santiago Arturo Merino Benitez

Sun 12/6

11:10 pm-11:25 am

1 stop15h 15m

$1,215

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 34 resultsSorted by cheapest first
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Best time to book a flight from Houston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago

What is the cheapest month to book a flight from Houston to Santiago?

Currently, February is the cheapest month in which you can book a flight from Houston to Santiago (average of $1,126). Flying from Houston to Santiago in May is currently the most expensive (average of $2,231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated August 1, 2026.
See what other customers who have flown with United Airlines and American Airlines from Houston to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
10,062 reviews

Entertainment

7.1

Crew

8.1

Food

6.7

Comfort

7.3

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
10,062 reviews
United Airlines
7.4
Good
10,062 reviews

Entertainment

7.1

Crew

8.1

Food

6.7

Comfort

7.3

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.1
Good
11,845 reviews
United Airlines
7.4
Good
10,062 reviews

Entertainment

7.1

Crew

8.1

Food

6.7

Comfort

7.3

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Houston?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Houston. Booking flights from Houston to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Houston from 2 different airlines.

  • How long is the flight from Houston to Santiago?

    Departing from Houston to Santiago will take you 16h 50m. Houston and Santiago are separated by a distance of 4637 mi.

  • What are the cheapest airlines flying from Houston to Santiago round-trip?

    Cheapflights users have booked flights from Houston to Santiago round-trip from $949. Another airline that can offer you cheap pricing is American Airlines. Users have found that United Airlines is 41% cheaper than the other options available to this destination.

  • Can I find deals for flights from Houston to Santiago that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago.

  • Can I find deals for business class flights from Houston to Santiago?

    Yes. Cheapflights offers flight deals from Houston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago?

    Currently, February is the cheapest month in which you can book a flight from Houston to Santiago (average of $1,126). Flying from Houston to Santiago in May is currently the most expensive (average of $2,231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Houston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to Santiago flights
George Bush Intcntl to Santiago flights
Austin to Santiago flights
San Antonio to Santiago flights

Top 2 airlines flying from Houston to Santiago

Discover the top 2 airlines that operate flights from Houston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$949Average$1,267FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$1,005Average$1,462FlexibilityNo cancel feeOn-time71%

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