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$242+ Cheap flights from Houston to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — SCL
dic. 12 — dic. 191
vie. 12/12
vie. 12/19
1 adult, Economy
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Cheap flight deals from Houston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated noviembre 12, 2025.

Round-trip from

$601
(Mytrip)

One-way from

$242
(eDestinos)

Popular in

June

Cheapest in

April

Average price

$893
From Houston to Santiago Arturo Merino Benitez
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One-way flight from Houston to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 3% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($33 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Houston to Santiago

Cheapest flights from Houston to Santiago
Explore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 12, 2025.

This Mytrip deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/65:25 pmIAH - SCL
2 stops33h 25mMultiple Airlines
dom. 12/149:05 pmSCL - IAH
2 stops29h 54mMultiple Airlines
Deal found 11/10$601
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/118:35 pmIAH - SCL
2 stops30h 15mMultiple Airlines
sáb. 11/155:50 amSCL - IAH
2 stops16h 40mMultiple Airlines
Deal found 11/11$713
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/2212:09 pmHOU - SCL
1 stop16h 36mAmerican Airlines
lun. 1/1210:35 pmSCL - HOU
2 stops16h 34mAmerican Airlines
Deal found 11/11$1,325
This SmartFares deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/186:00 amHOU - SCL
1 stop21h 10mLATAM Airlines
jue. 12/2511:10 pmSCL - HOU
1 stop13h 51mLATAM Airlines
Deal found 11/11$1,361
This LATAM Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/223:25 pmHOU - SCL
2 stops21h 05mLATAM Airlines
lun. 1/1211:10 pmSCL - HOU
1 stop14h 11mLATAM Airlines
Deal found 11/10$1,389
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/273:25 pmHOU - SCL
2 stops19h 40mDelta
mié. 12/3111:10 pmSCL - HOU
1 stop18h 28mDelta
Deal found 11/11$1,464
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/44:25 pmHOU - SCL
1 stop12h 20mAmerican Airlines
jue. 12/1111:15 pmSCL - HOU
1 stop13h 23mAmerican Airlines
Deal found 11/10$1,489
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/612:16 pmHOU - SCL
1 stop16h 29mAmerican Airlines
dom. 12/1411:15 pmSCL - HOU
1 stop21h 44mAmerican Airlines
Deal found 11/10$1,569
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2512:09 pmHOU - SCL
2 stops18h 16mAmerican Airlines
jue. 1/111:15 pmSCL - HOU
1 stop19h 32mAmerican Airlines
Deal found 11/10$1,590

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 12, 2025.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Houston

Fly to

Santiago

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

jue. 4/9

5:15 am-6:50 am

3 stops24h 35m

Santiago Arturo Merino Benitez

vie. 4/17

4:55 am-12:10 pm

3 stops32h 15m

$786

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

jue. 1/22

12:10 pm-6:50 am

1 stop15h 40m

Santiago Arturo Merino Benitez

vie. 1/30

12:40 am-3:38 pm

2 stops17h 58m

$845

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

lun. 2/2

8:45 pm-8:50 am

Nonstop9h 05m

Santiago Arturo Merino Benitez

mar. 2/17

10:45 pm-5:05 am

Nonstop9h 20m

$950

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

lun. 2/2

8:45 pm-8:50 am

Nonstop9h 05m

Santiago Arturo Merino Benitez

mié. 2/18

10:45 pm-5:05 am

Nonstop9h 20m

$950

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

jue. 1/1

10:46 am-5:50 am

2 stops16h 04m

Santiago Arturo Merino Benitez

jue. 1/15

8:10 am-10:35 pm

2 stops17h 25m

$955

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

jue. 1/1

3:25 pm-7:40 am

1 stop13h 15m

Santiago Arturo Merino Benitez

mié. 1/14

9:30 pm-10:21 am

1 stop15h 51m

$957

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

jue. 1/1

7:00 am-5:50 am

2 stops19h 50m

Santiago Arturo Merino Benitez

mié. 1/14

6:30 pm-9:30 am

2 stops18h 00m

$957

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

lun. 2/2

5:04 pm-3:30 pm

2 stops19h 26m

Santiago Arturo Merino Benitez

lun. 2/16

12:20 am-9:30 pm

2 stops24h 10m

$964

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

lun. 2/2

5:04 pm-3:30 pm

2 stops19h 26m

Santiago Arturo Merino Benitez

mar. 2/17

6:30 pm-10:05 am

2 stops18h 35m

$964

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

lun. 2/2

12:40 pm-7:40 am

1 stop16h 00m

Santiago Arturo Merino Benitez

lun. 2/16

12:20 am-9:15 pm

2 stops23h 55m

$964

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 28 results
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Best time to book a flight from Houston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago

What is the cheapest month to book a flight from Houston to Santiago?

Currently, November is the cheapest month in which you can book a flight from Houston to Santiago (average of $325). Flying from Houston to Santiago in February is currently the most expensive (average of $949). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to SCL?

Find hourly flight availability from Houston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Houston to Santiago at noon. If you’re flexible enough to do this you can expect to save up to 36% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Houston to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Houston to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Houston to Santiago flight should consider departing on Friday at noon when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated noviembre 12, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Houston to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,873 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,015 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Avianca
6.6
Okay
2,472 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Houston?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Houston. Booking flights from Houston to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Houston from 5 different airlines.

  • How long is the flight from Houston to Santiago?

    Departing from Houston to Santiago will take you 9h 05m. Houston and Santiago are separated by a distance of 4661 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Houston to Santiago round-trip?

    Cheapflights users have booked flights from Houston to Santiago round-trip from $499. Other airlines that can offer you cheap pricing are United Airlines, from $949, and Delta, from $963. Users have found that Avianca is 59% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Houston to Santiago one-way?

    To fly one-way, consider booking your trip with Air Canada, which is currently one of the cheapest options available, starting at $348. American Airlines flights start at $958 while deals on LATAM Airlines start at $983 one-way.

  • Can I find deals for flights from Houston to Santiago that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago.

  • Can I find deals for business class flights from Houston to Santiago?

    Yes. Cheapflights offers flight deals from Houston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Houston to Santiago (average of $325). Flying from Houston to Santiago in February is currently the most expensive (average of $949). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Houston to Santiago

Discover the top 5 airlines that operate flights from Houston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$499Average$677FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$949Average$1,497FlexibilityNo cancel feeOn-time69%
DeltaCheapest$963Average$1,193FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$963Average$1,352FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$1,242Average$1,581FlexibilityNo cancel feeOn-time71%

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