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$343+ Cheap flights from Houston to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — SCL
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Houston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$666
(Mytrip)

One-way from

$343
(Kiwi.com)

Popular in

December

Cheapest in

March

Average price

$1,583
From Houston to Santiago Arturo Merino Benitez
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One-way flight from Houston to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 10% potential increase in price ($148 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Houston to Santiago

Cheapest flights from Houston to Santiago
Explore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/62:35 pmIAH - SCL
2 stops35h 00mMultiple Airlines
Sun 10/1212:55 amSCL - IAH
2 stops17h 15mMultiple Airlines
Deal found 6/12$666
This Priceline deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/175:40 pmIAH - SCL
3 stops30h 10mAvianca
Tue 6/2411:55 pmSCL - IAH
2 stops17h 15mAvianca
Deal found 6/10$706
This FlightHub deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:00 pmIAH - SCL
1 stop12h 00mLATAM Airlines
Mon 10/1310:55 pmSCL - IAH
2 stops15h 24mLATAM Airlines
Deal found 6/12$927
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1210:44 amHOU - SCL
1 stop19h 16mLATAM Airlines
Tue 8/198:40 pmSCL - HOU
1 stop16h 30mLATAM Airlines
Deal found 6/9$949
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:35 pmHOU - SCL
2 stops19h 25mDelta
Tue 9/235:55 pmSCL - HOU
2 stops24h 32mDelta
Deal found 6/10$964
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:25 pmHOU - SCL
1 stop16h 25mAmerican Airlines
Mon 12/1511:15 pmSCL - HOU
1 stop13h 10mAmerican Airlines
Deal found 6/11$1,004
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:30 pmIAH - SCL
1 stop14h 30mDelta
Fri 11/2811:15 pmSCL - IAH
1 stop18h 43mDelta
Deal found 6/11$1,034
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/228:45 pmIAH - SCL
Nonstop9h 05mUnited Airlines
Mon 12/110:45 pmSCL - IAH
Nonstop9h 20mUnited Airlines
Deal found 6/11$1,048
This Air Canada deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/287:20 amIAH - SCL
1 stop25h 50mAir Canada
Tue 12/28:50 pmSCL - IAH
2 stops27h 29mAir Canada
Deal found 6/11$1,085
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:51 amIAH - SCL
1 stop20h 59mAmerican Airlines
Tue 12/3011:15 pmSCL - IAH
1 stop20h 49mAmerican Airlines
Deal found 6/11$1,104
This Aeromexico deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:39 amIAH - SCL
1 stop31h 36mAeromexico
Sun 11/3011:25 pmSCL - IAH
1 stop19h 16mAeromexico
Deal found 6/10$1,134

Cheapflights Fare Finder

Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Houston

Fly to

Santiago

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 10/6

2:35 pm-3:35 am

2 stops35h 00m

Santiago Arturo Merino Benitez

Sun 10/12

12:55 am-4:10 pm

2 stops17h 15m

$666

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sun 10/12

5:40 pm-2:25 pm

2 stops18h 45m

Santiago Arturo Merino Benitez

Sun 10/19

12:55 am-4:10 pm

2 stops17h 15m

$719

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 10/6

5:00 pm-7:00 am

1 stop12h 00m

Santiago Arturo Merino Benitez

Mon 10/13

10:55 pm-12:19 pm

2 stops15h 24m

$927

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 8/12

10:44 am-7:00 am

1 stop19h 16m

Santiago Arturo Merino Benitez

Tue 8/19

8:40 pm-12:10 pm

1 stop16h 30m

$949

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 9/16

5:35 pm-3:00 pm

2 stops19h 25m

Santiago Arturo Merino Benitez

Tue 9/23

5:55 pm-4:27 pm

2 stops24h 32m

$964

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Sat 11/15

12:25 pm-7:50 am

1 stop16h 25m

Santiago Arturo Merino Benitez

Mon 12/15

11:15 pm-9:25 am

1 stop13h 10m

$1,004

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 10/31

2:30 pm-7:00 am

1 stop14h 30m

Santiago Arturo Merino Benitez

Fri 11/28

11:15 pm-2:58 pm

1 stop18h 43m

$1,034

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sat 11/22

8:45 pm-8:50 am

Nonstop9h 05m

Santiago Arturo Merino Benitez

Mon 12/1

10:45 pm-5:05 am

Nonstop9h 20m

$1,048

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 11/28

7:20 am-12:10 pm

1 stop25h 50m

Santiago Arturo Merino Benitez

Tue 12/2

8:50 pm-9:19 pm

2 stops27h 29m

$1,085

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 11/21

10:39 am-9:15 pm

1 stop31h 36m

Santiago Arturo Merino Benitez

Sun 11/30

11:25 pm-3:41 pm

1 stop19h 16m

$1,134

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 18 results
1
2

Best time to book a flight from Houston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago

What is the cheapest month to book a flight from Houston to Santiago?

Currently, April is the cheapest month in which you can book a flight from Houston to Santiago (average of $752). Flying from Houston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to SCL?

Find hourly flight availability from Houston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Houston to Santiago at noon. If you’re flexible enough to do this you can expect to save up to 57% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Houston to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Houston to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Houston to Santiago flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 12, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines and Qantas Airways from Houston to Santiago by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Qantas Airways
7.5
Good
854 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Aeromexico
7.5
Good
1,706 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Houston?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Houston. Booking flights from Houston to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Houston from 5 different airlines.

  • What are the cheapest airlines flying from Houston to Santiago round-trip?

    Cheapflights users have booked flights from Houston to Santiago round-trip from $719. Other airlines that can offer you cheap pricing are LATAM Airlines, from $927, and Delta, from $964. Users have found that Avianca is 45% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Houston to Santiago one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $366. LATAM Airlines flights start at $871 while deals on American Airlines start at $1,153 one-way.

  • Can I find deals for flights from Houston to Santiago that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago.

  • Can I find deals for business class flights from Houston to Santiago?

    Yes. Cheapflights offers flight deals from Houston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Houston to Santiago (average of $752). Flying from Houston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Houston to Santiago

Discover the top 5 airlines that operate flights from Houston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$499Average$678FlexibilityNo cancel feeOn-time71%
American AirlinesCheapest$632Average$1,543FlexibilityNo cancel feeOn-time71%
DeltaCheapest$842Average$1,403FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$1,319Average$1,496FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$1,337Average$1,555FlexibilityNo cancel feeOn-time69%

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