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$279+ Cheap flights from Houston to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — SCL
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Houston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 1, 2025.

Round-trip from

$591
(Mytrip)

One-way from

$279
(eDestinos)

Popular in

December

Cheapest in

March

Average price

$847
From Houston to Santiago Arturo Merino Benitez
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One-way flight from Houston to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 14% potential increase in price ($215 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($47 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Houston to Santiago

Cheapest flights from Houston to Santiago
Explore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/25:40 pmIAH - SCL
2 stops18h 45mAvianca
Sat 6/72:30 pmSCL - IAH
2 stops22h 40mAvianca
Deal found 4/30$591
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:00 amIAH - SCL
3 stops30h 25mMultiple Airlines
Thu 5/223:35 amSCL - IAH
2 stops29h 18mMultiple Airlines
Deal found 4/30$686
This Air Canada deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:20 amIAH - SCL
1 stop25h 50mAir Canada
Thu 12/118:50 pmSCL - IAH
1 stop17h 22mAir Canada
Deal found 4/30$1,156
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/161:00 pmHOU - SCL
1 stop17h 00mLATAM Airlines
Tue 9/239:40 pmSCL - HOU
1 stop13h 43mLATAM Airlines
Deal found 4/30$1,296
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/161:15 pmIAH - SCL
1 stop16h 45mLATAM Airlines
Tue 9/239:40 pmSCL - IAH
1 stop16h 39mLATAM Airlines
Deal found 4/30$1,296
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:43 pmHOU - SCL
2 stops18h 17mDelta
Tue 9/233:20 pmSCL - HOU
2 stops22h 52mDelta
Deal found 4/30$1,364
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/227:58 pmIAH - SCL
1 stop34h 02mDelta
Mon 6/308:40 pmSCL - IAH
1 stop15h 12mDelta
Deal found 4/30$1,375
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:20 pmIAH - SCL
Nonstop9h 30mUnited Airlines
Fri 12/1210:45 pmSCL - IAH
Nonstop9h 45mUnited Airlines
Deal found 4/29$1,429
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/112:30 pmHOU - SCL
2 stops15h 30mAmerican Airlines
Wed 6/189:55 pmSCL - HOU
2 stops19h 01mAmerican Airlines
Deal found 4/29$1,443
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:07 amIAH - SCL
1 stop22h 43mAmerican Airlines
Tue 12/3011:45 pmSCL - IAH
1 stop12h 40mAmerican Airlines
Deal found 4/29$1,504
This Aeromexico deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:19 pmIAH - SCL
1 stop24h 56mAeromexico
Sun 12/2111:25 pmSCL - IAH
1 stop12h 48mAeromexico
Deal found 4/30$1,519
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/229:57 amIAH - SCL
1 stop12h 11mCopa Airlines
Sat 8/3012:12 amSCL - IAH
1 stop20h 38mCopa Airlines
Deal found 4/29$1,582

Cheapflights Fare Finder

Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Houston

Fly to

Santiago

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 6/2

5:40 pm-1:25 pm

2 stops18h 45m

Santiago Arturo Merino Benitez

Sat 6/7

2:30 pm-12:10 pm

2 stops22h 40m

$591

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 5/12

6:00 am-1:25 pm

3 stops30h 25m

Santiago Arturo Merino Benitez

Thu 5/22

3:35 am-7:53 am

2 stops29h 18m

$686

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 9/16

1:00 pm-8:00 am

1 stop17h 00m

Santiago Arturo Merino Benitez

Tue 9/23

9:40 pm-9:23 am

1 stop13h 43m

$1,296

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 9/16

1:15 pm-8:00 am

1 stop16h 45m

Santiago Arturo Merino Benitez

Tue 9/23

9:40 pm-12:19 pm

1 stop16h 39m

$1,296

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 9/16

6:43 pm-3:00 pm

2 stops18h 17m

Santiago Arturo Merino Benitez

Tue 9/23

3:20 pm-12:12 pm

2 stops22h 52m

$1,364

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sun 6/22

7:58 pm-7:00 am

1 stop34h 02m

Santiago Arturo Merino Benitez

Mon 6/30

8:40 pm-10:52 am

1 stop15h 12m

$1,375

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Wed 6/11

2:30 pm-7:00 am

2 stops15h 30m

Santiago Arturo Merino Benitez

Wed 6/18

9:55 pm-3:56 pm

2 stops19h 01m

$1,443

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 8/22

9:57 am-11:08 pm

1 stop12h 11m

Santiago Arturo Merino Benitez

Sat 8/30

12:12 am-7:50 pm

1 stop20h 38m

$1,582

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sat 5/17

12:09 pm-6:55 am

1 stop17h 46m

Santiago Arturo Merino Benitez

Thu 5/29

9:00 pm-5:19 pm

1 stop21h 19m

$1,829

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 7/29

5:40 pm-1:25 pm

2 stops18h 45m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 14 results
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Best time to book a flight from Houston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago

What is the cheapest month to book a flight from Houston to Santiago?

Currently, April is the cheapest month in which you can book a flight from Houston to Santiago (average of $752). Flying from Houston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to SCL?

Find hourly flight availability from Houston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

A simple way to save on the total cost of your ticket is to fly from Houston to Santiago at noon. If you’re flexible enough to do this you can expect to save up to 57% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Houston to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Houston to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Houston to Santiago flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 1, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines and Copa Airlines from Houston to Santiago by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,414 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Houston?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Houston. Booking flights from Houston to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Houston from 4 different airlines.

  • What are the cheapest airlines flying from Houston to Santiago round-trip?

    Cheapflights users have booked flights from Houston to Santiago round-trip from $591. Other airlines that can offer you cheap pricing are LATAM Airlines, from $1,296, and Delta, from $1,364. Users have found that Avianca is 54% cheaper than the other options available to this destination.

  • Can I find deals for flights from Houston to Santiago that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago.

  • Can I find deals for business class flights from Houston to Santiago?

    Yes. Cheapflights offers flight deals from Houston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Houston to Santiago (average of $752). Flying from Houston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Houston to Santiago

Discover the top 4 airlines that operate flights from Houston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$479Average$1,523FlexibilityNo cancel feeOn-time71%
AviancaCheapest$499Average$696FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$892Average$1,461FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$1,337Average$1,536FlexibilityNo cancel feeOn-time69%

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