$535+ Cheap flights from Honolulu (HNL) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
HNL — SCL
Apr 14 — Apr 211
Round-trip
1 adult, Economy
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Cheapest flights from Honolulu to SantiagoExplore the most affordable flight options available from Honolulu to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
Explore the most affordable flight options available from Honolulu to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
This Gurufare deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:30 pm
HNL
- SCL
2 stops25h 20m
LATAM Airlines
Thu 5/214:25 pm
SCL
- HNL
2 stops25h 25m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$1,161
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:45 pm
HNL
- SCL
2 stops27h 20m
American Airlines
Thu 5/218:35 pm
SCL
- HNL
2 stops30h 08m
American Airlines
Deal found 3/10![American Airlines logo]()
$1,166
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/183:14 pm
HNL
- SCL
1 stop34h 01m
Delta
Thu 5/218:40 pm
SCL
- HNL
2 stops30h 26m
Delta
Deal found 3/10![Delta logo]()
$1,183
This SmartFares deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:34 pm
HNL
- SCL
1 stop27h 01m
Multiple Airlines
Sun 5/38:40 pm
SCL
- HNL
1 stop23h 05m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$1,197
This KAYAK deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:00 am
HNL
- SCL
2 stops26h 30m
LATAM Airlines
Sat 10/1711:25 pm
SCL
- HNL
1 stop23h 47m
LATAM Airlines
Deal found 3/14![LATAM Airlines logo]()
$1,204
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:35 pm
HNL
- SCL
2 stops26h 50m
LATAM Airlines
Sun 5/38:40 pm
SCL
- HNL
1 stop23h 05m
LATAM Airlines
Deal found 3/12![LATAM Airlines logo]()
$1,221
This Gurufare deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:35 pm
HNL
- SCL
2 stops26h 15m
LATAM Airlines
Sat 5/27:55 pm
SCL
- HNL
2 stops26h 41m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$1,225
This Air Canada deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:00 pm
HNL
- SCL
2 stops30h 15m
Air Canada
Mon 11/28:55 pm
SCL
- HNL
2 stops31h 38m
Air Canada
Deal found 3/10![Air Canada logo]()
$1,230
This LATAM Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:26 pm
HNL
- SCL
3 stops36h 38m
Multiple Airlines
Sat 5/26:00 pm
SCL
- HNL
2 stops31h 49m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$1,245
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:57 pm
HNL
- SCL
2 stops26h 53m
American Airlines
Sat 10/109:30 pm
SCL
- HNL
2 stops31h 14m
American Airlines
Deal found 3/14![American Airlines logo]()
$1,280
Best flights from Honolulu to SantiagoDiscover carefully curated flight deals from Honolulu to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
Discover carefully curated flight deals from Honolulu to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
This Gurufare deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:30 pm
HNL
- SCL
2 stops25h 20m
LATAM Airlines
Thu 5/214:25 pm
SCL
- HNL
2 stops25h 25m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$1,161
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:45 pm
HNL
- SCL
2 stops27h 20m
American Airlines
Thu 5/218:35 pm
SCL
- HNL
2 stops30h 08m
American Airlines
Deal found 3/10![American Airlines logo]()
$1,166
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/183:14 pm
HNL
- SCL
1 stop34h 01m
Delta
Thu 5/218:40 pm
SCL
- HNL
2 stops30h 26m
Delta
Deal found 3/10![Delta logo]()
$1,183
This SmartFares deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:34 pm
HNL
- SCL
1 stop27h 01m
Multiple Airlines
Sun 5/38:40 pm
SCL
- HNL
1 stop23h 05m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$1,197
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:35 pm
HNL
- SCL
3 stops31h 29m
LATAM Airlines
Sun 5/38:40 pm
SCL
- HNL
1 stop23h 05m
LATAM Airlines
Deal found 3/12![LATAM Airlines logo]()
$1,221
This LATAM Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:26 pm
HNL
- SCL
3 stops36h 38m
Multiple Airlines
Sat 5/26:00 pm
SCL
- HNL
2 stops31h 49m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$1,245
This Gurufare deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:35 pm
HNL
- SCL
2 stops26h 15m
LATAM Airlines
Sat 5/27:55 pm
SCL
- HNL
2 stops26h 41m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$1,225
This Mytrip deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:55 pm
HNL
- SCL
2 stops26h 25m
Multiple Airlines
Thu 5/213:20 pm
SCL
- HNL
3 stops35h 20m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$2,109
Last-minute flights from Honolulu to SantiagoDiscover last-minute flight deals from Honolulu to Santiago. Data last updated March 15, 2026 and is based on user searches.
Discover last-minute flight deals from Honolulu to Santiago. Data last updated March 15, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/139:55 pm
HNL
- SCL
2 stops26h 55m
United Airlines
Fri 3/209:45 pm
SCL
- HNL
1 stop23h 18m
United Airlines
Deal found 3/13![United Airlines logo]()
$1,825
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/151:00 pm
HNL
- SCL
2 stops39h 15m
Multiple Airlines
Sun 3/2210:30 am
SCL
- HNL
2 stops34h 46m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$1,599
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/153:50 pm
HNL
- SCL
1 stop32h 50m
LATAM Airlines
Sun 3/224:20 pm
SCL
- HNL
2 stops52h 56m
LATAM Airlines
Deal found 3/12![LATAM Airlines logo]()
$1,780
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:30 pm
HNL
- SCL
1 stop27h 30m
American Airlines
Sun 3/2210:15 pm
SCL
- HNL
1 stop25h 25m
American Airlines
Deal found 3/12![American Airlines logo]()
$1,982
This Gurufare deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:35 pm
HNL
- SCL
2 stops26h 15m
LATAM Airlines
Sat 5/27:55 pm
SCL
- HNL
2 stops26h 41m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$1,225
This LATAM Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:26 pm
HNL
- SCL
3 stops36h 38m
Multiple Airlines
Sat 5/26:00 pm
SCL
- HNL
2 stops31h 49m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$1,245
This SmartFares deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:34 pm
HNL
- SCL
1 stop27h 01m
Multiple Airlines
Sun 5/38:40 pm
SCL
- HNL
1 stop23h 05m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$1,197
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:35 pm
HNL
- SCL
2 stops26h 50m
LATAM Airlines
Sun 5/38:40 pm
SCL
- HNL
1 stop23h 05m
LATAM Airlines
Deal found 3/12![LATAM Airlines logo]()
$1,221
One-way flights from Honolulu to SantiagoSearch for one-way flight options from Honolulu to Santiago. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
Search for one-way flight options from Honolulu to Santiago. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
This KAYAK deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:00 am
HNL
- SCL
2 stops28h 25m
LATAM Airlines
Deal found 3/13![LATAM Airlines logo]()
$535
This SmartFares deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:34 pm
HNL
- SCL
1 stop27h 01m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:00 pm
HNL
- SCL
2 stops28h 05m
American Airlines
Deal found 3/15![American Airlines logo]()
$561
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/293:26 pm
HNL
- SCL
1 stop33h 49m
Delta
Deal found 3/13![Delta logo]()
$584
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/228:38 am
HNL
- SCL
3 stops32h 11m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$741
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/219:40 am
HNL
- SCL
3 stops39h 00m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$795
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:45 pm
HNL
- SCL
3 stops26h 50m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$817
This LATAM Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/228:39 pm
HNL
- SCL
1 stop25h 56m
LATAM Airlines
Deal found 3/12![LATAM Airlines logo]()
$842
Find flight deals from Honolulu to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Honolulu (HNL) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $1,161 (Gurufare) |
One-way from | $535 (KAYAK) |
Cheapflights Fare Finder
Customize your flight search to find flights from Honolulu to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Honolulu to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Mon 5/18
9:30 pm-4:50 am
2 stops25h 20m
Santiago Arturo Merino Benitez
Thu 5/21
4:25 pm-11:50 am
2 stops25h 25m
$1,161
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Mon 5/18
9:45 pm-7:05 am
2 stops27h 20m
Santiago Arturo Merino Benitez
Thu 5/21
8:35 pm-8:43 pm
2 stops30h 08m
$1,166
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Mon 5/18
3:14 pm-7:15 am
1 stop34h 01m
Santiago Arturo Merino Benitez
Thu 5/21
8:40 pm-9:06 pm
2 stops30h 26m
$1,183
Quickest round-trip
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Sun 4/26
8:34 pm-5:35 am
1 stop27h 01m
Santiago Arturo Merino Benitez
Sun 5/3
8:40 pm-1:45 pm
1 stop23h 05m
$1,197
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Sun 4/26
8:35 pm-10:04 am
3 stops31h 29m
Santiago Arturo Merino Benitez
Sun 5/3
8:40 pm-1:45 pm
1 stop23h 05m
$1,221
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Sat 4/25
8:35 pm-4:50 am
2 stops26h 15m
Santiago Arturo Merino Benitez
Sat 5/2
7:55 pm-4:36 pm
2 stops26h 41m
$1,225
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Sat 4/25
3:26 pm-10:04 am
3 stops36h 38m
Santiago Arturo Merino Benitez
Sat 5/2
6:00 pm-7:49 pm
2 stops31h 49m
$1,245
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Mon 5/18
9:55 pm-6:20 am
2 stops26h 25m
Santiago Arturo Merino Benitez
Thu 5/21
3:20 pm-8:40 pm
3 stops35h 20m
$2,109
Cheapest one-way
Quickest one-way
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Sun 5/10
8:34 pm-5:35 am
1 stop27h 01m
$559
HonoluluSantiago
HNL - SCL
HNLSCL
Honolulu
Wed 4/29
8:35 pm-1:25 pm
3 stops34h 50m
$561
Showing 1-10 of 12 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Honolulu-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Honolulu-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Honolulu-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Honolulu-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Honolulu-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Honolulu to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Honolulu with our price prediction graph.
HNL-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 15, 2026.
Peruse reviews from past customers who have flown with Delta and LATAM Airlines from Honolulu to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Overall
7.9
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Overall
7.9
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Overall
7.9
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Honolulu to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Honolulu to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Honolulu to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Honolulu and Santiago flights
Browse other Honolulu and Santiago flight options. Last updated on March 15, 2026.
Other flights from Honolulu
Browse through other flights departing from Honolulu. Flights are based on user searches made on Cheapflights and were last updated on March 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 15, 2026.
Top 2 airlines flying from Honolulu to Santiago
Discover the top 2 airlines that operate flights from Honolulu to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,014 | Average$1,118 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$1,053 | Average$1,363 | FlexibilityNo cancel fee | On-time81% |