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$273+ Cheap flights from Guatemala City (GUA) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
GUA — SCL
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheapflights Tip: The best prices from Guatemala City La Aurora to Santiago Arturo Merino Benitez are usually found in August or May, booked 3 days in advance, depart on a Saturday or Sunday and return on a Friday

Cheap flight deals from Guatemala City to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Guatemala City (GUA) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$530
(Mytrip)

One-way from

$273
(Mytrip)

Popular in

December

Cheapest in

August

Average price

$525
From Guatemala City La Aurora to Santiago Arturo Merino Benitez
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One-way flight from Guatemala City La Aurora to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 11% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Guatemala City to Santiago

Cheapest flights from Guatemala City to Santiago
Explore the most affordable flight options available from Guatemala City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/254:10 pmGUA - SCL
1 stop10h 05mAvianca
Fri 10/312:55 amSCL - GUA
1 stop19h 20mAvianca
Deal found 7/28$530
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/239:40 amGUA - SCL
1 stop10h 50mMultiple Airlines
Sun 8/248:15 pmSCL - GUA
2 stops25h 35mMultiple Airlines
Deal found 7/28$537
This Copa Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/25:39 amGUA - SCL
2 stops21h 19mCopa Airlines
Sat 9/2012:29 pmSCL - GUA
2 stops12h 07mCopa Airlines
Deal found 7/28$551

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guatemala City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Guatemala City to Santiago that are best for you.

Fly from

Guatemala City

Fly to

Santiago

Route

Depart

Return

Price

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 9/25

4:10 pm-5:15 am

1 stop10h 05m

Santiago Arturo Merino Benitez

Fri 10/3

12:55 am-5:15 pm

1 stop19h 20m

$530

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sat 8/23

9:40 am-10:30 pm

1 stop10h 50m

Santiago Arturo Merino Benitez

Sun 8/24

8:15 pm-7:50 pm

2 stops25h 35m

$537

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Tue 9/2

5:39 am-7:20 pm

2 stops11h 41m

Santiago Arturo Merino Benitez

Fri 9/19

3:26 am-11:33 am

1 stop11h 07m

$551

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 9/1

9:40 am-10:30 pm

1 stop10h 50m

$273

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sun 8/10

5:39 am-2:46 am

2 stops19h 07m

$280

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 9/1

7:50 am-5:00 am

3 stops19h 10m

$326

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Guatemala City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Guatemala City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guatemala City to Santiago

What is the cheapest month to book a flight from Guatemala City to Santiago?

Currently, April is the cheapest month in which you can book a flight from Guatemala City to Santiago (average of $752). Flying from Guatemala City to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GUA to SCL?

Find hourly flight availability from Guatemala City to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

One of the essential ways to save on airfare from Guatemala City to Santiago is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 33% on airfare.

How much does it cost to fly round-trip from Guatemala City to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 30, 2025.
Read through reviews of airlines operating flights from Guatemala City to Santiago, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,493 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,493 reviews
Copa Airlines
7.5
Good
1,493 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,387 reviews
Copa Airlines
7.5
Good
1,493 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Guatemala City to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Guatemala City to Santiago round-trip?

    Currently priced at $530, Avianca will fly you from Guatemala City to Santiago and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Copa Airlines for as low as $551. Users have found that Avianca is 2% cheaper than the other options available to this destination.

  • Can I find deals for flights from Guatemala City to Santiago that include hotel bookings?

    Yes. In addition to deals on Guatemala City to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guatemala City to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala City to Santiago.

  • Can I find deals for business class flights from Guatemala City to Santiago?

    Yes. Cheapflights offers flight deals from Guatemala City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guatemala City to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Guatemala City to Santiago (average of $752). Flying from Guatemala City to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Top 2 airlines flying from Guatemala City to Santiago

Discover the top 2 airlines that operate flights from Guatemala City to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$375Average$550FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$400Average$642FlexibilityNo cancel feeOn-time70%

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