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$238+ Cheap flights from Guatemala City (GUA) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/7. Fares are subject to change and may not be available on all flights or dates of travel.
GUA — SCL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Guatemala City to Santiago

Cheapest flights from Guatemala City to Santiago
Explore the most affordable flight options available from Guatemala City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:55 pm
GUA
-
SCL
1 stop22h 25m
Avianca
Mon 3/234:25 pm
SCL
-
GUA
1 stop12h 15m
Avianca
Deal found 1/28$456
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:40 am
GUA
-
SCL
1 stop16h 35m
Avianca
Sun 5/1711:55 pm
SCL
-
GUA
1 stop17h 45m
Avianca
Deal found 1/27$468
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1310:34 am
GUA
-
SCL
1 stop10h 15m
Copa Airlines
Mon 3/235:21 am
SCL
-
GUA
2 stops19h 19m
Copa Airlines
Deal found 1/28$471
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:24 am
GUA
-
SCL
2 stops15h 10m
Copa Airlines
Fri 4/1011:25 am
SCL
-
GUA
1 stop13h 21m
Copa Airlines
Deal found 1/27$487
This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:55 pm
GUA
-
SCL
1 stop12h 35m
Avianca
Tue 3/177:25 am
SCL
-
GUA
1 stop13h 15m
Avianca
Deal found 1/26$495
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:45 am
GUA
-
SCL
1 stop10h 45m
Avianca
Tue 4/286:10 am
SCL
-
GUA
1 stop13h 05m
Avianca
Deal found 1/27$499
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:55 pm
GUA
-
SCL
1 stop12h 35m
Avianca
Sat 3/217:25 am
SCL
-
GUA
1 stop13h 15m
Avianca
Deal found 1/27$507

Find flight deals from Guatemala City to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Guatemala City (GUA) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$456
(Priceline)

One-way from

$238
(Priceline)

Popular in

December

Cheapest in

May

Average price

$575
Provider with most accurate pricing for Guatemala City La Aurora-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guatemala City La Aurora-Santiago Arturo Merino Benitez flights.
Search Deals
From Guatemala City La Aurora to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Guatemala City La Aurora to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guatemala City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Guatemala City to Santiago that are best for you.

Fly from

Guatemala City

Fly to

Santiago

Route

Depart

Return

Price

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 3/19

2:26 am-11:49 pm

1 stop18h 23m

Santiago Arturo Merino Benitez

Sun 3/29

5:19 am-11:03 pm

1 stop20h 44m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Tue 4/14

7:12 am-11:26 pm

1 stop14h 14m

Santiago Arturo Merino Benitez

Wed 4/22

2:30 am-11:50 am

1 stop11h 20m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Fri 5/15

6:24 am-11:26 pm

2 stops15h 02m

Santiago Arturo Merino Benitez

Mon 5/18

11:17 am-9:41 pm

2 stops12h 24m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 4/30

6:24 am-7:23 pm

2 stops10h 59m

Santiago Arturo Merino Benitez

Fri 5/8

11:17 am-10:44 pm

1 stop13h 27m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sun 4/19

6:24 am-11:26 pm

2 stops15h 02m

Santiago Arturo Merino Benitez

Tue 4/28

4:17 am-9:41 pm

2 stops19h 24m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 4/20

4:26 am-10:43 pm

1 stop16h 17m

Santiago Arturo Merino Benitez

Fri 4/24

11:25 am-11:10 pm

1 stop13h 45m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Fri 5/1

6:24 am-10:43 pm

2 stops14h 19m

Santiago Arturo Merino Benitez

Sat 5/2

4:09 am-9:41 pm

2 stops19h 32m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Fri 4/17

7:12 am-10:43 pm

1 stop13h 31m

Santiago Arturo Merino Benitez

Fri 4/24

11:25 am-8:01 pm

1 stop10h 36m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sun 5/10

4:24 am-7:23 pm

1 stop12h 59m

Santiago Arturo Merino Benitez

Sat 5/16

4:09 am-10:44 pm

1 stop20h 35m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sun 6/7

9:45 am-4:15 am

1 stop16h 30m

$238

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 14 results
1
2
  • Most accurate provider: When it comes to deals on Guatemala City-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guatemala City-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guatemala City-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guatemala City-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guatemala City-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guatemala City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Guatemala City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guatemala City to Santiago

What is the cheapest month to book a flight from Guatemala City to Santiago?

Currently, June is the cheapest month in which you can book a flight from Guatemala City to Santiago (average of $230). Flying from Guatemala City to Santiago in March is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 29, 2026.
Read through reviews of airlines operating flights from Guatemala City to Santiago, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,560 reviews

Overall

7.5

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Maria,Dec 2025

MIA - PTY

The second flight to salta Argentina was terrible..the plain is old no entertainment no good food no nothing
Copa Airlines
7.5
Good
1,560 reviews
Copa Airlines
7.5
Good
1,560 reviews

Overall

7.5

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Maria,Dec 2025

MIA - PTY

The second flight to salta Argentina was terrible..the plain is old no entertainment no good food no nothing
Avianca
6.6
Okay
2,490 reviews
Copa Airlines
7.5
Good
1,560 reviews

Overall

7.5

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Maria,Dec 2025

MIA - PTY

The second flight to salta Argentina was terrible..the plain is old no entertainment no good food no nothing

Related info for your journey

Find useful and relevant information for your journey from Guatemala City to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Guatemala City to Santiago?

    For as low as $471, Copa Airlines can have you in Santiago from Guatemala City in 18h 23m. Guatemala City and Santiago are separated by a distance of 3559 mi.

  • What are the cheapest airlines flying from Guatemala City to Santiago round-trip?

    Currently priced at $279, Copa Airlines will fly you from Guatemala City to Santiago and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Avianca for as low as $407. Users have found that Copa Airlines is 49% cheaper than the other options available to this destination.

  • Can I find deals for flights from Guatemala City to Santiago that include hotel bookings?

    Yes. In addition to deals on Guatemala City to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guatemala City to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala City to Santiago.

  • Can I find deals for business class flights from Guatemala City to Santiago?

    Yes. Cheapflights offers flight deals from Guatemala City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guatemala City to Santiago?

    Currently, June is the cheapest month in which you can book a flight from Guatemala City to Santiago (average of $230). Flying from Guatemala City to Santiago in March is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Lastarria car rentals

Top 2 airlines flying from Guatemala City to Santiago

Discover the top 2 airlines that operate flights from Guatemala City to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$279Average$566FlexibilityNo cancel feeOn-time70%
AviancaCheapest$407Average$534FlexibilityNo cancel feeOn-time71%

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