What’s the cheapest layover airport for flights from Boston to Santiago?

Atlanta (ATL) is the most affordable 1-stop option, with an average round-trip price of $816.

What’s the top layover airport for flights from Boston to Santiago?

Atlanta (ATL) – chosen by Cheapflights users on 50% of 1-stop itineraries from Boston to Santiago on Cheapflights.

Which airport typically offers the quickest layover for flights from Boston to Santiago?

Flights via Atlanta (ATL) offer the fastest connection on this route, with an average layover time of 1h 15m.

What’s the fastest layover option from Boston to Santiago?

Flights via Atlanta (ATL) have the shortest average one-way travel time for 1-stop routes: 12h 55m.

How long is the flight from Boston to Santiago?

For as low as $632, Avianca can have you in Santiago from Boston in 14h 35m. The distance from Boston to Santiago is about 5231 mi.

What are the cheapest airlines flying from Boston to Santiago round-trip?

Our cheapest airline available from Boston to Santiago is Avianca. Our recent data shows that you can find tickets from as low as $442 on this airline. Additional options worth looking into are LATAM Airlines and Delta, starting at $513 and $518 round-trip. Avianca is 48% cheaper than the average price of flights available within the next 90 days to this destination.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

What are the most popular airlines that fly from Boston to Santiago?

American Airlines, Air Canada and Avianca are the most popular airlines when flying from Boston to Santiago.

Where are the most common layover locations when flying from Boston to Santiago?

Most of the time, Boston to Santiago flights that have layovers will stop in Miami.

Where are the least popular layover locations for Boston to Santiago flights?

The least popular layover on flights from Boston to Santiago is Atlanta.

What are some popular things to do or see while on a layover in Miami?

If you're on a layover in Miami and looking for things to do, consider visiting Bayfront Park, Kaseya Center, or Wynwood Art District. Bayfront Park, Kaseya Center and Wynwood Art District are located about 6.4 mi, 6.2 mi, and 5.5 mi, respectively from Miami if you are interested in checking them out. Travelers can rent a car at Miami for an average daily rate of $22 to make sightseeing during their layover a little easier.

Most accurate provider : When it comes to deals on Boston-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Boston-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Boston-Santiago flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Boston-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Boston-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Boston to Santiago that include hotel bookings?

Yes. In addition to deals on Boston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Boston to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Boston to Santiago.

Can I find deals for business class flights from Boston to Santiago?

Yes. Cheapflights offers flight deals from Boston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$276+ Flights from Boston to Santiago

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Boston Logan Intl to Santiago Arturo Merino Benitez are usually found in September or October, booked 39 days in advance, depart on a Sunday or Monday and return on a Thursday

Cheap flight deals from Boston to Santiago

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$560 (Mytrip)
One-way from	$276 (Kiwi.com)
Popular in	December
Cheapest in	September
Average price	$688

Provider with most accurate pricing for Boston Logan Intl-Santiago Arturo Merino Benitez flight deals.

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Provider most trusted by Cheapflights users for Boston Logan Intl-Santiago Arturo Merino Benitez flights.

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From Boston Logan Intl to Santiago Arturo Merino Benitez

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One-way flight from Boston Logan Intl to Santiago Arturo Merino Benitez

Search Deals

Highest demand for flights based on searches. 1% potential increase in price ($15 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Boston to Santiago

Cheapest flights from Boston to Santiago
Explore the most affordable flight options available from Boston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

Thu 10/2311:44 amBOS - SCL

2 stops33h 31mMultiple Airlines

Wed 11/54:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/24

$567

Thu 10/2311:44 amBOS - SCL

2 stops50h 01mMultiple Airlines

Thu 10/3010:50 amSCL - BOS

1 stop30h 06mMultiple Airlines

Deal found 9/23

$593

Sun 11/911:18 amBOS - SCL

2 stops25h 22mMultiple Airlines

Sat 11/1510:50 amSCL - BOS

1 stop25h 33mMultiple Airlines

Deal found 9/23

$606

Sat 10/42:18 pmBOS - SCL

2 stops38h 42mMultiple Airlines

Fri 10/107:10 amSCL - BOS

1 stop25h 05mMultiple Airlines

Deal found 9/23

$609

Sun 11/911:18 amBOS - SCL

2 stops25h 22mMultiple Airlines

Sun 11/1612:30 pmSCL - BOS

3 stops31h 32mMultiple Airlines

Deal found 9/24

$610

Wed 10/226:16 amBOS - SCL

3 stops31h 29mMultiple Airlines

Wed 10/294:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/24

$617

Mon 10/204:50 pmBOS - SCL

3 stops35h 11mMultiple Airlines

Fri 10/317:25 amSCL - BOS

1 stop25h 10mMultiple Airlines

Deal found 9/25

$619

Tue 10/216:16 amBOS - SCL

3 stops31h 29mMultiple Airlines

Tue 10/284:25 pmSCL - BOS

2 stops23h 25mMultiple Airlines

Deal found 9/23

$625

Tue 10/216:16 amBOS - SCL

3 stops31h 29mMultiple Airlines

Mon 10/274:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/23

$628

Tue 11/117:55 amBOS - SCL

1 stop14h 35mAvianca

Mon 11/174:25 pmSCL - BOS

1 stop16h 10mAvianca

Deal found 9/23

$632

Sat 10/252:15 pmBOS - SCL

2 stops37h 40mMultiple Airlines

Mon 11/104:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/23

$633

Best flights from Boston to Santiago
Discover carefully curated flight deals from Boston to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2025.

Mon 10/204:50 pmBOS - SCL

3 stops35h 11mMultiple Airlines

Fri 10/317:25 amSCL - BOS

1 stop25h 10mMultiple Airlines

Deal found 9/25

$619

Tue 11/117:55 amBOS - SCL

1 stop14h 35mAvianca

Mon 11/174:25 pmSCL - BOS

1 stop16h 10mAvianca

Deal found 9/23

$632

Mon 11/103:59 pmBOS - SCL

1 stop13h 01mLATAM Airlines

Sun 11/161:25 pmSCL - BOS

1 stop19h 10mLATAM Airlines

Deal found 9/23

$680

Tue 10/219:00 amBOS - SCL

2 stops20h 00mMultiple Airlines

Thu 10/3010:50 amSCL - BOS

1 stop30h 06mMultiple Airlines

Deal found 9/22

$659

Tue 10/79:00 amBOS - SCL

1 stop19h 15mAvianca

Thu 10/163:30 pmSCL - BOS

2 stops24h 25mAvianca

Deal found 9/25

$698

Mon 12/13:59 pmBOS - SCL

2 stops20h 31mLATAM Airlines

Sat 12/66:42 pmSCL - BOS

2 stops37h 53mLATAM Airlines

Deal found 9/24

$702

Fri 12/56:15 amBOS - SCL

2 stops31h 05mMultiple Airlines

Sun 12/149:10 pmSCL - BOS

3 stops22h 52mMultiple Airlines

Deal found 9/22

$676

Fri 11/73:25 pmBOS - SCL

2 stops21h 55mAvianca

Thu 11/131:35 amSCL - BOS

1 stop31h 00mAvianca

Deal found 9/22

$732

Wed 10/222:15 pmBOS - SCL

2 stops36h 27mMultiple Airlines

Wed 10/294:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/24

$678

Fri 11/75:45 amBOS - SCL

3 stops30h 55mMultiple Airlines

Fri 11/147:25 amSCL - BOS

1 stop25h 10mMultiple Airlines

Deal found 9/22

$726

Last-minute flights from Boston to Santiago
Discover last-minute flight deals from Boston to Santiago. Data last updated September 25, 2025 and is based on user searches.

Sat 10/42:18 pmBOS - SCL

2 stops38h 42mMultiple Airlines

Fri 10/107:10 amSCL - BOS

1 stop25h 05mMultiple Airlines

Deal found 9/23

$609

Sat 10/1812:31 pmBOS - SCL

3 stops38h 57mMultiple Airlines

Tue 10/284:25 pmSCL - BOS

2 stops23h 25mMultiple Airlines

Deal found 9/24

$636

Mon 10/204:50 pmBOS - SCL

3 stops35h 11mMultiple Airlines

Fri 10/317:25 amSCL - BOS

1 stop25h 10mMultiple Airlines

Deal found 9/25

$619

Tue 10/216:16 amBOS - SCL

3 stops31h 29mMultiple Airlines

Tue 10/284:25 pmSCL - BOS

2 stops23h 25mMultiple Airlines

Deal found 9/23

$625

Tue 10/216:16 amBOS - SCL

3 stops31h 29mMultiple Airlines

Mon 10/274:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/23

$628

Tue 10/219:00 amBOS - SCL

1 stop19h 15mAvianca

Tue 10/284:25 pmSCL - BOS

2 stops23h 25mAvianca

Deal found 9/23

$634

Wed 10/226:16 amBOS - SCL

3 stops31h 29mMultiple Airlines

Wed 10/294:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/24

$617

Thu 10/2311:44 amBOS - SCL

2 stops33h 31mMultiple Airlines

Wed 11/54:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/24

$567

Thu 10/2311:44 amBOS - SCL

2 stops50h 01mMultiple Airlines

Thu 10/3010:50 amSCL - BOS

1 stop30h 06mMultiple Airlines

Deal found 9/23

$593

Thu 10/239:00 amBOS - SCL

1 stop13h 30mAvianca

Wed 11/54:25 pmSCL - BOS

1 stop16h 10mAvianca

Deal found 9/24

$632

Sat 10/252:15 pmBOS - SCL

2 stops37h 40mMultiple Airlines

Mon 11/104:25 pmSCL - BOS

1 stop16h 10mMultiple Airlines

Deal found 9/23

$633

One-way flights from Boston to Santiago
Search for one-way flight options from Boston to Santiago. Find affordable one-way fares based on user searches. Data last updated September 25, 2025.

Thu 12/1112:20 pmBOS - SCL

2 stops31h 55mMultiple Airlines

Deal found 9/25

$276

Sat 10/48:38 amBOS - SCL

3 stops44h 22mMultiple Airlines

Deal found 9/22

$301

Sat 10/256:16 amBOS - SCL

3 stops41h 14mMultiple Airlines

Deal found 9/24

$322

Sat 10/49:00 amBOS - SCL

1 stop13h 30mAvianca

Deal found 9/22

$334

Sat 10/1812:31 pmBOS - SCL

3 stops38h 57mMultiple Airlines

Deal found 9/25

$343

Sun 10/126:16 amBOS - SCL

3 stops31h 09mMultiple Airlines

Deal found 9/22

$352

Sat 10/259:00 amBOS - SCL

1 stop13h 30mAvianca

Deal found 9/24

$363

Fly from

Fly to

Route

Depart

Return

Price

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Mon 10/20

4:50 pm-5:01 am

3 stops35h 11m

Santiago Arturo Merino Benitez

Fri 10/31

7:25 am-7:35 am

1 stop25h 10m

$619

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Tue 11/11

7:55 am-12:30 am

1 stop14h 35m

Santiago Arturo Merino Benitez

Mon 11/17

4:25 pm-6:35 am

1 stop16h 10m

$632

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Tue 10/21

9:00 am-6:00 am

2 stops20h 00m

Santiago Arturo Merino Benitez

Thu 10/30

10:50 am-3:56 pm

1 stop30h 06m

$659

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Fri 12/5

6:15 am-3:20 pm

2 stops31h 05m

Santiago Arturo Merino Benitez

Sun 12/14

9:10 pm-6:02 pm

3 stops22h 52m

$676

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Wed 10/22

2:15 pm-3:42 am

2 stops36h 27m

Santiago Arturo Merino Benitez

Wed 10/29

4:25 pm-7:35 am

1 stop16h 10m

$678

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Mon 11/10

3:59 pm-7:00 am

1 stop13h 01m

Santiago Arturo Merino Benitez

Sun 11/16

1:25 pm-6:35 am

1 stop19h 10m

$680

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Tue 10/7

9:00 am-5:15 am

1 stop19h 15m

Santiago Arturo Merino Benitez

Thu 10/16

3:30 pm-2:55 pm

2 stops24h 25m

$698

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Mon 12/1

3:59 pm-2:30 pm

2 stops20h 31m

Santiago Arturo Merino Benitez

Sat 12/6

6:42 pm-6:35 am

2 stops37h 53m

$702

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Fri 11/7

5:45 am-2:40 pm

3 stops30h 55m

Santiago Arturo Merino Benitez

Fri 11/14

7:25 am-6:35 am

1 stop25h 10m

$726

BostonSantiago

BOS - SCL

BOSSCL

Boston Logan Intl

Fri 11/7

3:25 pm-3:20 pm

2 stops21h 55m

Santiago Arturo Merino Benitez

Thu 11/13

1:35 am-6:35 am

1 stop31h 00m

$732

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/25

Showing 1-10 of 18 results

Compare providers for flights from Boston to Santiago

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Boston to Santiago in September.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars
Cheapflightsfares	Price Accuracy2 stars	Trust Score*1 star
Trip.com	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Boston-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Boston-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Boston-Santiago flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Boston-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Boston-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Boston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Boston with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Boston to Santiago

Prices

How far ahead should I book a flight from Boston to Santiago?

Booking 39 days in advance of your planned departure date is, on average, the best time to get cheap flights from Boston to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Boston to Santiago?

Currently, April is the cheapest month in which you can book a flight from Boston to Santiago (average of $752). Flying from Boston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BOS to SCL?

A simple way to save on the total cost of your ticket is to fly from Boston to Santiago in the evening. If you’re flexible enough to do this you can expect to save up to 36% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Boston to Santiago?

Travelers seeking maximum savings on their Boston to Santiago flight should consider departing on Wednesday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santiago

Get a feel of what it's like to fly with Delta, Copa Airlines, and LATAM Airlines from Boston to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,973 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.6

Good

1,539 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

LATAM Airlines

7.5

Good

1,855 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Avianca

6.7

Okay

2,442 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

How long is the flight from Boston to Santiago?
For as low as $632, Avianca can have you in Santiago from Boston in 14h 35m. The distance from Boston to Santiago is about 5231 mi.
What are the cheapest airlines flying from Boston to Santiago round-trip?
Our cheapest airline available from Boston to Santiago is Avianca. Our recent data shows that you can find tickets from as low as $442 on this airline. Additional options worth looking into are LATAM Airlines and Delta, starting at $513 and $518 round-trip. Avianca is 48% cheaper than the average price of flights available within the next 90 days to this destination.
Where are the most common layover locations when flying from Boston to Santiago?
Most of the time, Boston to Santiago flights that have layovers will stop in Miami.
What are some popular things to do or see while on a layover in Miami?
If you're on a layover in Miami and looking for things to do, consider visiting Bayfront Park, Kaseya Center, or Wynwood Art District. Bayfront Park, Kaseya Center and Wynwood Art District are located about 6.4 mi, 6.2 mi, and 5.5 mi, respectively from Miami if you are interested in checking them out. Travelers can rent a car at Miami for an average daily rate of $22 to make sightseeing during their layover a little easier.
Where are the least popular layover locations for Boston to Santiago flights?
The least popular layover on flights from Boston to Santiago is Atlanta.
Can I find deals for flights from Boston to Santiago that include hotel bookings?
Yes. In addition to deals on Boston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Boston to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Boston to Santiago.
Can I find deals for business class flights from Boston to Santiago?
Yes. Cheapflights offers flight deals from Boston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Boston to Santiago?
Currently, April is the cheapest month in which you can book a flight from Boston to Santiago (average of $752). Flying from Boston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Boston to Santiago

Hartford to Santiago flights

Boston to Punta Arenas flights

Boston to Concepción flights

Boston to Easter Island flights

Boston to La Serena flights

Other flights to Santiago

Top 7 airlines flying from Boston to Santiago

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$442	Average$732	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$513	Average$845	FlexibilityNo cancel fee	On-time81%
Delta	Cheapest$518	Average$931	FlexibilityNo cancel fee	On-timeN/A
Copa Airlines	Cheapest$521	Average$797	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$548	Average$930	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$672	Average$692	FlexibilityNo cancel fee	On-time69%
Air Canada	Cheapest$688	Average$793	FlexibilityNo cancel fee	On-time67%

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$276+ Cheap flights from Boston (BOS) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheapflights Tip: The best prices from Boston Logan Intl to Santiago Arturo Merino Benitez are usually found in September or October, booked 39 days in advance, depart on a Sunday or Monday and return on a Thursday

Cheap flight deals from Boston to Santiago

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Boston to Santiago

Cheapest flights from Boston to SantiagoExplore the most affordable flight options available from Boston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

Explore the most affordable flight options available from Boston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Boston to Santiago that are best for you.

Compare providers for flights from Boston to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Boston to Santiago in September.

Best time to book a flight from Boston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Boston with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Boston to Santiago

How far ahead should I book a flight from Boston to Santiago?

What is the cheapest month to book a flight from Boston to Santiago?

What is the cheapest time of day to fly from BOS to SCL?

What is the cheapest day to fly from Boston to Santiago?

What’s the top layover airport for flights from Boston to Santiago?

What’s the fastest layover option from Boston to Santiago?

What’s the fastest layover option from Boston to Santiago?

Which airport typically offers the quickest layover for flights from Boston to Santiago?

Reviews of airlines servicing Santiago

Get a feel of what it's like to fly with Delta, Copa Airlines, and LATAM Airlines from Boston to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Boston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Boston to Santiago?

What are the cheapest airlines flying from Boston to Santiago round-trip?

Where are the most common layover locations when flying from Boston to Santiago?

What are some popular things to do or see while on a layover in Miami?

Where are the least popular layover locations for Boston to Santiago flights?

Can I find deals for flights from Boston to Santiago that include hotel bookings?

How can I find direct flights from Boston to Santiago?

Can I find deals for business class flights from Boston to Santiago?

What is the cheapest month to book a flight from Boston to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Boston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Boston to Santiago

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Cheapest flights from Boston to Santiago
Explore the most affordable flight options available from Boston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.