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$220+ Cheap flights from Missouri to Santa Fe (SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAF
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Missouri to Santa Fe

Keep the following information in mind while searching for Missouri to Santa Fe flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$227
(United Airlines)

One-way from

$220
(American Airlines)

Popular in

June

Cheapest in

September

Average price

$439
Provider with most accurate pricing for Kansas City-Santa Fe flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Santa Fe flights.
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From Missouri to Santa Fe
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One-way flight from Missouri to Santa Fe
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Highest demand for flights based on searches. 16% potential increase in price ($74 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Missouri to Santa Fe

Cheapest flights from Missouri to Santa Fe
Explore the most affordable flight options available from Missouri to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:00 amMCI - SAF
1 stop4h 22mUnited Airlines
Mon 6/25:59 pmSAF - MCI
1 stop4h 30mUnited Airlines
Deal found 4/30$227
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/75:49 pmMCI - SAF
1 stop5h 09mAmerican Airlines
Wed 6/114:50 pmSAF - MCI
1 stop5h 23mAmerican Airlines
Deal found 5/1$244
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:27 amSGF - SAF
1 stop5h 03mAmerican Airlines
Tue 5/132:14 pmSAF - SGF
1 stop7h 12mAmerican Airlines
Deal found 4/30$279
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/85:15 amSTL - SAF
1 stop5h 07mUnited Airlines
Thu 7/241:23 pmSAF - STL
1 stop7h 27mUnited Airlines
Deal found 4/30$314
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/114:17 pmSTL - SAF
1 stop6h 36mAmerican Airlines
Tue 9/165:01 pmSAF - STL
1 stop4h 26mAmerican Airlines
Deal found 5/1$325
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:29 pmJLN - SAF
1 stop19h 06mUnited Airlines
Sat 6/77:05 amSAF - JLN
1 stop8h 54mUnited Airlines
Deal found 4/30$464

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Missouri to Santa Fe that are best for you.

Fly from

Missouri

Fly to

Santa Fe

Route

Depart

Return

Price

Kansas CitySanta Fe

MCI - SAF

MCISAF

Kansas City

Fri 5/30

6:00 am-9:22 am

1 stop4h 22m

Santa Fe

Mon 6/2

5:59 pm-11:29 pm

1 stop4h 30m

$227

Kansas CitySanta Fe

MCI - SAF

MCISAF

Kansas City

Sat 6/7

5:49 pm-9:58 pm

1 stop5h 09m

Santa Fe

Wed 6/11

4:50 pm-11:13 pm

1 stop5h 23m

$244

St. LouisSanta Fe

STL - SAF

STLSAF

Lambert-St Louis

Tue 7/8

5:15 am-9:22 am

1 stop5h 07m

Santa Fe

Thu 7/24

1:23 pm-9:50 pm

1 stop7h 27m

$314

St. LouisSanta Fe

STL - SAF

STLSAF

Lambert-St Louis

Thu 9/11

4:17 pm-9:53 pm

1 stop6h 36m

Santa Fe

Tue 9/16

5:01 pm-10:27 pm

1 stop4h 26m

$325

JoplinSanta Fe

JLN - SAF

JLNSAF

Joplin

Fri 5/30

6:29 pm-12:35 pm

1 stop19h 06m

Santa Fe

Sat 6/7

7:05 am-4:59 pm

1 stop8h 54m

$464

SpringfieldSanta Fe

SGF - SAF

SGFSAF

Springfield-Branson

Thu 6/19

6:29 pm-9:58 pm

1 stop4h 29m

$220

Kansas CitySanta Fe

MCI - SAF

MCISAF

Kansas City

Sun 6/15

6:05 am-9:22 am

1 stop4h 17m

$255

Kansas CitySanta Fe

MCI - SAF

MCISAF

Kansas City

Sun 5/11

5:15 am-11:51 am

1 stop7h 36m

$322

SpringfieldSanta Fe

SGF - SAF

SGFSAF

Springfield-Branson

Thu 6/19

3:00 pm-9:58 pm

2 stops31h 58m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/1

Best time to book a flight from Missouri to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Fe

What is the cheapest month to book a flight from Missouri to Santa Fe?

Currently, January is the cheapest month in which you can book a flight from Missouri to Santa Fe (average of $372). Flying from Missouri to Santa Fe in March is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Santa Fe by month

Plan your trip to Santa Fe by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santa Fe ranges from 0.5 - 2.6 inches per month. August is typically the wettest month, when rainfall can reach 2.6 in. February is typically the driest time to visit Santa Fe when rainfall is around 0.5 in.

Temperature in Santa Fe by month

Plan your trip to Santa Fe by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santa Fe, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated May 1, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Missouri to Santa Fe to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,696 reviews

Food

6.6

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,696 reviews
United Airlines
7.4
Good
8,696 reviews

Food

6.6

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,696 reviews

Food

6.6

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Missouri?

    Most people fly into Santa Fe (SAF) if they book a flight to Santa Fe from Missouri. Santa Fe is conveniently located just 9.8 mi from Santa Fe’s city center.

  • What are the most popular routes from Missouri to Santa Fe?

    When deciding which route to take from Missouri to Santa Fe consider Kansas City - Santa Fe, Lambert-St Louis - Santa Fe or Joplin - Santa Fe as they are the most popular.

  • Can I find deals for flights from Missouri to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Missouri to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Fe.

  • Can I find deals for business class flights from Missouri to Santa Fe?

    Yes. Cheapflights offers flight deals from Missouri to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Santa Fe?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Santa Fe (average of $372). Flying from Missouri to Santa Fe in March is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Santa Rosa

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Top 2 airlines flying from Missouri to Santa Fe

Discover the top 2 airlines that operate flights from Missouri to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$243Average$415FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$244Average$451FlexibilityNo cancel feeOn-time69%

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