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$236+ Cheap flights from Missouri to Santa Fe (SAF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAF
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
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Cheap flight deals from Missouri to Santa Fe

Keep the following information in mind while searching for Missouri to Santa Fe flight deals. Data was last updated July 2, 2025.

Round-trip from

$244
(American Airlines)

Popular in

March

Cheapest in

July

Average price

$270
From Missouri to Santa Fe
Search Deals
High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Missouri to Santa Fe

Cheapest flights from Missouri to Santa Fe
Explore the most affordable flight options available from Missouri to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:00 amMCI - SAF
1 stop5h 13mAmerican Airlines
Sat 10/255:07 pmSAF - MCI
1 stop4h 43mAmerican Airlines
Deal found 7/1$236
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:18 amSTL - SAF
1 stop5h 15mAmerican Airlines
Sat 9/207:15 amSAF - STL
1 stop6h 54mAmerican Airlines
Deal found 6/30$244
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/306:00 amMCI - SAF
1 stop4h 23mUnited Airlines
Tue 9/25:59 pmSAF - MCI
1 stop4h 28mUnited Airlines
Deal found 7/1$306
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/265:15 amSTL - SAF
1 stop5h 07mUnited Airlines
Tue 7/295:59 pmSAF - STL
1 stop5h 00mUnited Airlines
Deal found 7/2$343
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/175:45 amSGF - SAF
1 stop4h 37mUnited Airlines
Mon 7/217:05 amSAF - SGF
1 stop4h 56mUnited Airlines
Deal found 7/2$650

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from Missouri to Santa Fe that are best for you.

Fly from

Missouri

Fly to

Santa Fe

Route

Depart

Return

Price

St. LouisSanta Fe

STL - SAF

STLSAF

Lambert-St Louis

Tue 9/16

5:18 am-9:33 am

1 stop5h 15m

Santa Fe

Sat 9/20

7:15 am-3:09 pm

1 stop6h 54m

$244

Kansas CitySanta Fe

MCI - SAF

MCISAF

Kansas City

Sat 8/30

6:00 am-9:23 am

1 stop4h 23m

Santa Fe

Tue 9/2

5:59 pm-11:27 pm

1 stop4h 28m

$306

St. LouisSanta Fe

STL - SAF

STLSAF

Lambert-St Louis

Sat 7/26

5:15 am-9:22 am

1 stop5h 07m

Santa Fe

Tue 7/29

5:59 pm-11:59 pm

1 stop5h 00m

$343

Kansas CitySanta Fe

MCI - SAF

MCISAF

Kansas City

Sat 7/12

2:28 pm-6:48 pm

1 stop5h 20m

Santa Fe

Wed 7/16

4:48 pm-11:12 pm

1 stop5h 24m

$365

SpringfieldSanta Fe

SGF - SAF

SGFSAF

Springfield-Branson

Thu 7/17

5:45 am-9:22 am

1 stop4h 37m

Santa Fe

Mon 7/21

7:05 am-1:01 pm

1 stop4h 56m

$650

St. LouisSanta Fe

STL - SAF

STLSAF

Lambert-St Louis

Fri 7/18

10:08 am-4:13 pm

1 stop7h 05m

$322

St. LouisSanta Fe

STL - SAF

STLSAF

Lambert-St Louis

Fri 7/18

8:00 am-5:11 pm

2 stops10h 11m

$327

Kansas CitySanta Fe

MCI - SAF

MCISAF

Kansas City

Sun 8/10

6:00 am-9:22 am

1 stop4h 22m

$393

Kansas CitySanta Fe

MCI - SAF

MCISAF

Kansas City

Sun 7/6

7:00 am-12:22 pm

1 stop6h 22m

$442

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Missouri to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Fe

What is the cheapest month to book a flight from Missouri to Santa Fe?

Currently, January is the cheapest month in which you can book a flight from Missouri to Santa Fe (average of $372). Flying from Missouri to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated July 2, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from Missouri to Santa Fe by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,861 reviews

Food

6.6

Overall

7.4

Comfort

7.3

Entertainment

7.0

Crew

8.1

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,861 reviews
United Airlines
7.4
Good
8,861 reviews

Food

6.6

Overall

7.4

Comfort

7.3

Entertainment

7.0

Crew

8.1

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,861 reviews

Food

6.6

Overall

7.4

Comfort

7.3

Entertainment

7.0

Crew

8.1

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Missouri?

    Most people fly into Santa Fe (SAF) if they book a flight to Santa Fe from Missouri. Santa Fe is conveniently located just 9.8 mi from Santa Fe’s city center.

  • What are the most popular routes from Missouri to Santa Fe?

    When deciding which route to take from Missouri to Santa Fe consider Kansas City - Santa Fe, Lambert-St Louis - Santa Fe or Joplin - Santa Fe as they are the most popular.

  • Can I find deals for flights from Missouri to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Missouri to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Fe.

  • Can I find deals for business class flights from Missouri to Santa Fe?

    Yes. Cheapflights offers flight deals from Missouri to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Santa Fe?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Santa Fe (average of $372). Flying from Missouri to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Santa Rosa

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Top 2 airlines flying from Missouri to Santa Fe

Discover the top 2 airlines that operate flights from Missouri to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$243Average$410FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$244Average$457FlexibilityNo cancel feeOn-time69%

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