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Santa Cruz de la Sierra

$296+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Houston to Santa Cruz de la Sierra

Cheapest flights from Houston to Santa Cruz de la Sierra
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:34 amIAH - VVI
1 stop16h 02mCopa Airlines
Sat 12/271:09 amVVI - IAH
1 stop21h 01mCopa Airlines
Deal found 12/22$1,839
This Ovago deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:35 pmIAH - VVI
2 stops26h 11mMultiple Airlines
Sun 12/285:25 amVVI - IAH
1 stop28h 00mMultiple Airlines
Deal found 12/22$2,599
This KAYAK deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:08 amIAH - VVI
2 stops19h 27mLATAM Airlines
Sun 12/285:25 amVVI - IAH
2 stops20h 26mLATAM Airlines
Deal found 12/22$2,608

Find flight deals from Houston to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 23, 2025.

Round-trip from

$733
(United Airlines)

One-way from

$296
(Kiwi.com)

Popular in

July

Cheapest in

April

Average price

$1,225
From Houston to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Houston to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 20% potential increase in price ($262 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($55 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.

Fly from

Houston

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sun 2/22

8:34 pm-10:50 pm

2 stops24h 16m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/17

11:42 am-11:14 am

2 stops24h 32m

$742

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 1/20

9:40 pm-10:50 pm

2 stops23h 10m

Santa Cruz de la Sierra Viru Viru Intl

Tue 1/27

11:44 am-6:07 am

2 stops20h 23m

$742

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sat 3/14

2:00 pm-2:35 am

2 stops35h 35m

Santa Cruz de la Sierra Viru Viru Intl

Fri 3/20

3:40 am-4:10 pm

2 stops37h 30m

$830

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Fri 2/20

7:20 am-2:35 am

2 stops17h 15m

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/26

3:40 am-3:10 pm

2 stops13h 30m

$830

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 1/20

7:45 am-2:35 am

2 stops16h 50m

Santa Cruz de la Sierra Viru Viru Intl

Mon 1/26

3:40 am-10:53 pm

3 stops21h 13m

$883

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Fri 2/20

4:22 pm-4:35 am

2 stops34h 13m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/27

8:35 am-5:30 pm

1 stop34h 55m

$923

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 2/2

1:00 pm-2:35 am

2 stops35h 35m

Santa Cruz de la Sierra Viru Viru Intl

Wed 2/4

3:40 am-3:10 pm

2 stops37h 30m

$958

HoustonSanta Cruz de la Sierra

HOU - VVI

HOUVVI

Houston Hobby

Thu 4/9

2:13 pm-4:30 am

2 stops37h 17m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/28

5:25 am-9:38 pm

2 stops41h 13m

$2,714

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 2/16

7:30 am-2:35 am

3 stops17h 05m

$296

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 2/16

9:34 am-10:50 pm

1 stop11h 16m

$715

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 11 results
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Best time to book a flight from Houston to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santa Cruz de la Sierra

What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $597). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,056). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated December 23, 2025.
Read reviews from past customers who have flown United Airlines and Avianca from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,105 reviews

Food

6.6

Entertainment

7.1

Boarding

7.7

Overall

7.4

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,105 reviews
United Airlines
7.4
Good
9,105 reviews

Food

6.6

Entertainment

7.1

Boarding

7.7

Overall

7.4

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
Avianca
6.6
Okay
2,492 reviews
United Airlines
7.4
Good
9,105 reviews

Food

6.6

Entertainment

7.1

Boarding

7.7

Overall

7.4

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Houston?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Houston to Santa Cruz de la Sierra. 2 airlines have flights to Viru Viru Intl from Houston on a regular basis. Booking flights from Houston to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Houston per day.

  • How long is the flight from Houston to Santa Cruz de la Sierra?

    For as low as $742, United Airlines can have you in Santa Cruz de la Sierra from Houston in 24h 16m. There are 3925 mi between Houston and Santa Cruz de la Sierra. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Houston to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Houston to Santa Cruz de la Sierra is Avianca. Our recent data shows that you can find tickets from as low as $586 on this airline. An additional option worth looking into is United Airlines, starting at $726. Avianca is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Houston to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Houston to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Houston to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Houston to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $597). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,056). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Houston to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$586Average$874FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$726Average$1,106FlexibilityNo cancel feeOn-time69%

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