Santa Cruz de la Sierra

$294+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Mar 6 — Mar 131
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Houston to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Houston to Santa Cruz de la Sierra

Cheapest flights from Houston to Santa Cruz de la Sierra
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:24 pm
IAH
-
VVI
2 stops33h 11m
Multiple Airlines
Tue 3/105:25 am
VVI
-
IAH
2 stops19h 34m
Multiple Airlines
Deal found 2/2$663
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:14 am
IAH
-
VVI
3 stops21h 21m
Multiple Airlines
Tue 3/245:25 am
VVI
-
IAH
2 stops19h 24m
Multiple Airlines
Deal found 2/1$745
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:10 am
IAH
-
VVI
2 stops15h 21m
United Airlines
Mon 3/911:54 am
VVI
-
IAH
2 stops21h 28m
United Airlines
Deal found 2/2$783
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:39 pm
IAH
-
VVI
1 stop13h 11m
Multiple Airlines
Sat 4/253:35 am
VVI
-
IAH
2 stops18h 03m
Multiple Airlines
Deal found 2/1$790
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:05 pm
IAH
-
VVI
2 stops35h 25m
Avianca
Sat 4/253:35 am
VVI
-
IAH
2 stops33h 30m
Avianca
Deal found 2/1$792
This KAYAK deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:20 pm
IAH
-
VVI
2 stops24h 30m
Copa Airlines
Mon 3/91:14 am
VVI
-
IAH
1 stop12h 00m
Copa Airlines
Deal found 2/2$800
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:24 pm
IAH
-
VVI
2 stops31h 11m
Multiple Airlines
Mon 3/98:35 am
VVI
-
IAH
1 stop16h 24m
Multiple Airlines
Deal found 2/2$804
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:45 pm
IAH
-
VVI
2 stops31h 45m
Avianca
Tue 5/53:35 am
VVI
-
IAH
2 stops37h 35m
Avianca
Deal found 2/3$811
This Gurufare deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:21 pm
IAH
-
VVI
2 stops25h 17m
Copa Airlines
Tue 6/231:12 am
VVI
-
IAH
1 stop19h 52m
Copa Airlines
Deal found 2/2$830
This Orbitz deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:25 am
HOU
-
VVI
2 stops21h 10m
LATAM Airlines
Tue 3/105:25 am
VVI
-
HOU
2 stops29h 58m
LATAM Airlines
Deal found 2/2$1,496
This FlightHub deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:05 am
HOU
-
VVI
2 stops41h 30m
LATAM Airlines
Mon 8/35:25 am
VVI
-
HOU
2 stops31h 39m
LATAM Airlines
Deal found 1/31$1,606
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:50 am
HOU
-
VVI
2 stops15h 45m
LATAM Airlines
Mon 3/95:25 am
VVI
-
HOU
2 stops29h 58m
LATAM Airlines
Deal found 2/2$2,237

Find flight deals from Houston to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 4, 2026.

Round-trip from

$663
(Trip.com)

One-way from

$294
(Kiwi.com)

Popular in

July

Cheapest in

April

Average price

$872
From Houston to Santa Cruz de la Sierra Viru Viru Intl
One-way flight from Houston to Santa Cruz de la Sierra Viru Viru Intl
Highest demand for flights based on searches. 24% potential increase in price ($309 potential increase over avg. RT price).
Cheapest flight prices on average. 6% potential price decrease ($59 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.

Fly from

Houston

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 3/3

5:24 pm-4:35 am

2 stops33h 11m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

5:25 am-11:59 pm

2 stops19h 34m

$663

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 3/17

6:14 am-4:35 am

3 stops21h 21m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

5:25 am-11:49 pm

2 stops19h 24m

$745

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 3/2

10:10 am-3:31 am

2 stops15h 21m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

11:54 am-8:22 am

2 stops21h 28m

$783

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 3/17

9:50 pm-10:50 pm

2 stops24h 00m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

11:54 am-12:34 pm

2 stops25h 40m

$783

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Thu 4/23

2:39 pm-4:50 am

1 stop13h 11m

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/25

3:35 am-8:38 pm

2 stops18h 03m

$790

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Wed 5/20

5:45 pm-2:30 am

2 stops31h 45m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/18

3:35 am-4:10 pm

2 stops37h 35m

$792

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 3/3

8:20 pm-10:50 pm

2 stops24h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

1:14 am-12:14 pm

1 stop12h 00m

$800

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Wed 6/3

11:59 am-3:31 am

1 stop14h 32m

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/23

1:12 am-8:04 pm

1 stop19h 52m

$804

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 3/2

5:24 pm-2:35 am

2 stops31h 11m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

8:35 am-11:59 pm

1 stop16h 24m

$804

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sat 5/2

2:05 pm-2:30 am

2 stops35h 25m

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

3:35 am-4:10 pm

2 stops13h 35m

$811

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 18 results
1
2

Best time to book a flight from Houston to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santa Cruz de la Sierra

What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $597). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,049). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Houston to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated February 4, 2026.
Read reviews from past customers who have flown United Airlines and Avianca from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santa Cruz de la Sierra from Houston?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Houston to Santa Cruz de la Sierra. 2 airlines have flights to Viru Viru Intl from Houston on a regular basis. Booking flights from Houston to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Houston per day.

  • How long is the flight from Houston to Santa Cruz de la Sierra?

    For as low as $783, United Airlines can have you in Santa Cruz de la Sierra from Houston in 15h 21m. There are 3925 mi between Houston and Santa Cruz de la Sierra. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Houston to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Houston to Santa Cruz de la Sierra is Avianca. Our recent data shows that you can find tickets from as low as $554 on this airline. An additional option worth looking into is United Airlines, starting at $726. Avianca is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Houston to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Houston to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Houston to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Houston to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $597). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,049). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Houston to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$554Average$814FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$726Average$1,106FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.