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Santa Cruz de la Sierra

$338+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Houston to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$741
(United Airlines)

One-way from

$338
(Kiwi.com)

Popular in

March

Cheapest in

April

Average price

$726
From Houston to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Houston to Santa Cruz de la Sierra Viru Viru Intl
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High demand for flights, 3% potential price rise
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Cheapest flight prices on average. 5% potential price decrease ($55 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Houston to Santa Cruz de la Sierra

Cheapest flights from Houston to Santa Cruz de la Sierra
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:20 amIAH - VVI
2 stops37h 26mUnited Airlines
Tue 12/91:09 amVVI - IAH
3 stops30h 38mUnited Airlines
Deal found 9/15$741
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/162:05 pmIAH - VVI
2 stops34h 45mAvianca
Mon 9/222:50 amVVI - IAH
2 stops34h 20mAvianca
Deal found 9/15$797
This United deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/274:40 pmIAH - VVI
1 stop31h 55mMultiple Airlines
Tue 12/91:09 amVVI - IAH
2 stops33h 34mMultiple Airlines
Deal found 9/15$811
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/232:05 pmIAH - VVI
2 stops34h 45mAvianca
Wed 10/293:40 amVVI - IAH
2 stops37h 30mAvianca
Deal found 9/15$898
This FlightHub deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:00 pmIAH - VVI
2 stops35h 35mAvianca
Tue 12/233:40 amVVI - IAH
2 stops33h 25mAvianca
Deal found 9/16$910
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/162:05 pmIAH - VVI
2 stops34h 45mMultiple Airlines
Mon 9/222:50 amVVI - IAH
3 stops30h 34mMultiple Airlines
Deal found 9/15$950
This Avianca deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:35 pmIAH - VVI
2 stops32h 00mAvianca
Wed 12/243:40 amVVI - IAH
2 stops13h 30mAvianca
Deal found 9/16$957
This Orbitz deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:00 pmIAH - VVI
2 stops35h 35mAvianca
Tue 12/233:40 amVVI - IAH
2 stops33h 25mAvianca
Deal found 9/16$990
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/272:32 pmHOU - VVI
2 stops36h 03mLATAM Airlines
Wed 12/105:25 amVVI - HOU
2 stops20h 21mLATAM Airlines
Deal found 9/15$1,167
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:37 pmHOU - VVI
2 stops32h 58mLATAM Airlines
Tue 9/235:20 amVVI - HOU
2 stops31h 58mLATAM Airlines
Deal found 9/15$2,974

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.

Fly from

Houston

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Thu 11/27

7:20 am-10:46 pm

2 stops37h 26m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/9

1:09 am-5:47 am

3 stops30h 38m

$741

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Thu 11/27

4:40 pm-2:35 am

1 stop31h 55m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/9

1:09 am-8:43 am

2 stops33h 34m

$811

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Thu 10/23

2:05 pm-1:50 am

2 stops34h 45m

Santa Cruz de la Sierra Viru Viru Intl

Wed 10/29

3:40 am-4:10 pm

2 stops37h 30m

$898

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 12/15

4:35 pm-2:35 am

2 stops32h 00m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/24

3:40 am-3:10 pm

2 stops13h 30m

$957

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sun 12/14

4:35 pm-2:35 am

2 stops32h 00m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/23

3:40 am-3:10 pm

2 stops37h 30m

$957

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 12/15

1:00 pm-2:35 am

2 stops35h 35m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/22

3:40 am-3:10 pm

2 stops13h 30m

$1,107

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 12/15

4:35 pm-2:35 am

2 stops32h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sat 12/20

3:40 am-11:05 am

2 stops33h 25m

$1,107

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 12/16

4:35 pm-2:35 am

2 stops32h 00m

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/26

3:40 am-11:05 am

2 stops33h 25m

$1,124

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 12/16

4:35 pm-2:35 am

2 stops32h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sat 12/20

3:40 am-3:10 pm

2 stops37h 30m

$1,124

HoustonSanta Cruz de la Sierra

HOU - VVI

HOUVVI

Houston Hobby

Thu 11/27

2:32 pm-4:35 am

2 stops36h 03m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/10

5:25 am-11:46 pm

2 stops20h 21m

$1,167

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 20 results
1
2

Best time to book a flight from Houston to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santa Cruz de la Sierra

What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $597). Flying from Houston to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated September 16, 2025.
Read reviews from past customers who have flown United Airlines and Avianca from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,924 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,924 reviews
United Airlines
7.4
Good
8,924 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
Avianca
6.7
Okay
2,435 reviews
United Airlines
7.4
Good
8,924 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Houston?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Houston to Santa Cruz de la Sierra. 2 airlines have flights to Viru Viru Intl from Houston on a regular basis. Booking flights from Houston to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Houston per day.

  • How long is the flight from Houston to Santa Cruz de la Sierra?

    For as low as $898, United Airlines can have you in Santa Cruz de la Sierra from Houston in 34h 45m. There are 3925 mi between Houston and Santa Cruz de la Sierra. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Houston to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Houston to Santa Cruz de la Sierra is Avianca. Our recent data shows that you can find tickets from as low as $586 on this airline. An additional option worth looking into is United Airlines, starting at $726. Avianca is priced at 45% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Houston to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Houston to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Houston to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Houston to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $597). Flying from Houston to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Houston to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$586Average$965FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$726Average$1,064FlexibilityNo cancel feeOn-time69%

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