$294+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Mar 6 — Mar 131
1 adult, Economy
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Find cheap flights from Houston to Santa Cruz de la Sierra with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Santa Cruz de la Sierra
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Cheapest flights from Houston to Santa Cruz de la SierraExplore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:24 pm
IAH
- VVI
2 stops33h 11m
Multiple Airlines
Tue 3/105:25 am
VVI
- IAH
2 stops19h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$663
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:14 am
IAH
- VVI
3 stops21h 21m
Multiple Airlines
Tue 3/245:25 am
VVI
- IAH
2 stops19h 24m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$745
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:10 am
IAH
- VVI
2 stops15h 21m
United Airlines
Mon 3/911:54 am
VVI
- IAH
2 stops21h 28m
United Airlines
Deal found 2/2![United Airlines logo]()
$783
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:39 pm
IAH
- VVI
1 stop13h 11m
Multiple Airlines
Sat 4/253:35 am
VVI
- IAH
2 stops18h 03m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$790
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:05 pm
IAH
- VVI
2 stops35h 25m
Avianca
Sat 4/253:35 am
VVI
- IAH
2 stops33h 30m
Avianca
Deal found 2/1![Avianca logo]()
$792
This KAYAK deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:20 pm
IAH
- VVI
2 stops24h 30m
Copa Airlines
Mon 3/91:14 am
VVI
- IAH
1 stop12h 00m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$800
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:24 pm
IAH
- VVI
2 stops31h 11m
Multiple Airlines
Mon 3/98:35 am
VVI
- IAH
1 stop16h 24m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$804
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Tue 5/53:35 am
VVI
- IAH
2 stops37h 35m
Avianca
Deal found 2/3![Avianca logo]()
$811
This Gurufare deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:21 pm
IAH
- VVI
2 stops25h 17m
Copa Airlines
Tue 6/231:12 am
VVI
- IAH
1 stop19h 52m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$830
This Orbitz deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:25 am
HOU
- VVI
2 stops21h 10m
LATAM Airlines
Tue 3/105:25 am
VVI
- HOU
2 stops29h 58m
LATAM Airlines
Deal found 2/2![LATAM Airlines logo]()
$1,496
This FlightHub deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:05 am
HOU
- VVI
2 stops41h 30m
LATAM Airlines
Mon 8/35:25 am
VVI
- HOU
2 stops31h 39m
LATAM Airlines
Deal found 1/31![LATAM Airlines logo]()
$1,606
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:50 am
HOU
- VVI
2 stops15h 45m
LATAM Airlines
Mon 3/95:25 am
VVI
- HOU
2 stops29h 58m
LATAM Airlines
Deal found 2/2![LATAM Airlines logo]()
$2,237
Best flights from Houston to Santa Cruz de la SierraDiscover carefully curated flight deals from Houston to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
Discover carefully curated flight deals from Houston to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:24 pm
IAH
- VVI
2 stops33h 11m
Multiple Airlines
Tue 3/105:25 am
VVI
- IAH
2 stops19h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$663
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:10 am
IAH
- VVI
2 stops15h 21m
United Airlines
Mon 3/911:54 am
VVI
- IAH
2 stops21h 28m
United Airlines
Deal found 2/2![United Airlines logo]()
$783
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:45 pm
IAH
- VVI
2 stops31h 45m
Avianca
Tue 8/183:35 am
VVI
- IAH
2 stops37h 35m
Avianca
Deal found 2/2![Avianca logo]()
$792
This KAYAK deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:20 pm
IAH
- VVI
2 stops24h 30m
Copa Airlines
Mon 3/91:14 am
VVI
- IAH
1 stop12h 00m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$800
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:14 am
IAH
- VVI
3 stops21h 21m
Multiple Airlines
Tue 3/245:25 am
VVI
- IAH
2 stops19h 24m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$745
This Orbitz deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:25 am
HOU
- VVI
2 stops21h 10m
LATAM Airlines
Tue 3/105:25 am
VVI
- HOU
2 stops29h 58m
LATAM Airlines
Deal found 2/2![LATAM Airlines logo]()
$1,496
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:50 pm
IAH
- VVI
2 stops24h 00m
United Airlines
Tue 3/2411:54 am
VVI
- IAH
2 stops25h 40m
United Airlines
Deal found 2/1![United Airlines logo]()
$783
This KAYAK deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:59 am
IAH
- VVI
1 stop14h 32m
Copa Airlines
Tue 6/231:12 am
VVI
- IAH
1 stop19h 52m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$804
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:05 pm
IAH
- VVI
2 stops35h 25m
Avianca
Tue 5/53:35 am
VVI
- IAH
2 stops13h 35m
Avianca
Deal found 2/1![Avianca logo]()
$811
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:39 pm
IAH
- VVI
1 stop13h 11m
Multiple Airlines
Sat 4/253:35 am
VVI
- IAH
2 stops18h 03m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$790
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:24 pm
IAH
- VVI
2 stops31h 11m
Multiple Airlines
Mon 3/98:35 am
VVI
- IAH
1 stop16h 24m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$804
This FlightHub deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:05 am
HOU
- VVI
2 stops41h 30m
LATAM Airlines
Mon 8/35:25 am
VVI
- HOU
2 stops31h 39m
LATAM Airlines
Deal found 1/31![LATAM Airlines logo]()
$1,606
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:50 am
HOU
- VVI
2 stops15h 45m
LATAM Airlines
Mon 3/95:25 am
VVI
- HOU
2 stops29h 58m
LATAM Airlines
Deal found 2/2![LATAM Airlines logo]()
$2,237
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1410:50 am
HOU
- VVI
2 stops39h 45m
LATAM Airlines
Sat 2/215:20 am
VVI
- HOU
2 stops19h 08m
LATAM Airlines
Deal found 2/1![LATAM Airlines logo]()
$2,708
This Ovago deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:12 am
HOU
- VVI
2 stops17h 23m
LATAM Airlines
Wed 6/248:41 am
VVI
- HOU
2 stops25h 39m
LATAM Airlines
Deal found 2/2![LATAM Airlines logo]()
$2,999
Last-minute flights from Houston to Santa Cruz de la SierraDiscover last-minute flight deals from Houston to Santa Cruz de la Sierra. Data last updated February 4, 2026 and is based on user searches.
Discover last-minute flight deals from Houston to Santa Cruz de la Sierra. Data last updated February 4, 2026 and is based on user searches.
This Ovago deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:04 pm
HOU
- VVI
2 stops33h 31m
LATAM Airlines
Wed 2/115:20 am
VVI
- HOU
2 stops30h 41m
LATAM Airlines
Deal found 2/3![LATAM Airlines logo]()
$2,586
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1410:50 am
HOU
- VVI
2 stops39h 45m
LATAM Airlines
Sat 2/215:20 am
VVI
- HOU
2 stops19h 08m
LATAM Airlines
Deal found 2/1![LATAM Airlines logo]()
$2,708
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:10 am
IAH
- VVI
2 stops15h 21m
United Airlines
Mon 3/911:54 am
VVI
- IAH
2 stops21h 28m
United Airlines
Deal found 2/2![United Airlines logo]()
$783
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:24 pm
IAH
- VVI
2 stops31h 11m
Multiple Airlines
Mon 3/98:35 am
VVI
- IAH
1 stop16h 24m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$804
This Gurufare deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:34 am
IAH
- VVI
1 stop11h 16m
Copa Airlines
Sun 3/81:14 am
VVI
- IAH
1 stop19h 56m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$834
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:50 am
HOU
- VVI
2 stops15h 45m
LATAM Airlines
Mon 3/95:25 am
VVI
- HOU
2 stops29h 58m
LATAM Airlines
Deal found 2/2![LATAM Airlines logo]()
$2,237
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:24 pm
IAH
- VVI
2 stops33h 11m
Multiple Airlines
Tue 3/105:25 am
VVI
- IAH
2 stops19h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$663
This KAYAK deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:20 pm
IAH
- VVI
2 stops24h 30m
Copa Airlines
Mon 3/91:14 am
VVI
- IAH
1 stop12h 00m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$800
This Orbitz deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:25 am
HOU
- VVI
2 stops21h 10m
LATAM Airlines
Tue 3/105:25 am
VVI
- HOU
2 stops29h 58m
LATAM Airlines
Deal found 2/2![LATAM Airlines logo]()
$1,496
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:14 am
IAH
- VVI
3 stops21h 21m
Multiple Airlines
Tue 3/245:25 am
VVI
- IAH
2 stops19h 24m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$745
One-way flights from Houston to Santa Cruz de la SierraSearch for one-way flight options from Houston to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
Search for one-way flight options from Houston to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:37 am
IAH
- VVI
2 stops13h 53m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$294
This Ovago deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:25 pm
IAH
- VVI
1 stop11h 05m
Avianca
Deal found 2/3![Avianca logo]()
$749
This Ovago deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:23 pm
HOU
- VVI
2 stops34h 12m
LATAM Airlines
Deal found 2/3![LATAM Airlines logo]()
$1,306
Find flight deals from Houston to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 4, 2026.
Round-trip from | $663 (Trip.com) |
|---|---|
One-way from | $294 (Kiwi.com) |
Popular in | July |
Cheapest in | April |
Average price | $872 |
Cheapflights Fare Finder
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.
Fly from
Houston
Fly to
Santa Cruz de la Sierra
Route
Depart
Return
Price
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Tue 3/3
5:24 pm-4:35 am
2 stops33h 11m
Santa Cruz de la Sierra Viru Viru Intl
Tue 3/10
5:25 am-11:59 pm
2 stops19h 34m
$663
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Tue 3/17
6:14 am-4:35 am
3 stops21h 21m
Santa Cruz de la Sierra Viru Viru Intl
Tue 3/24
5:25 am-11:49 pm
2 stops19h 24m
$745
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Mon 3/2
10:10 am-3:31 am
2 stops15h 21m
Santa Cruz de la Sierra Viru Viru Intl
Mon 3/9
11:54 am-8:22 am
2 stops21h 28m
$783
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Tue 3/17
9:50 pm-10:50 pm
2 stops24h 00m
Santa Cruz de la Sierra Viru Viru Intl
Tue 3/24
11:54 am-12:34 pm
2 stops25h 40m
$783
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Thu 4/23
2:39 pm-4:50 am
1 stop13h 11m
Santa Cruz de la Sierra Viru Viru Intl
Sat 4/25
3:35 am-8:38 pm
2 stops18h 03m
$790
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Wed 5/20
5:45 pm-2:30 am
2 stops31h 45m
Santa Cruz de la Sierra Viru Viru Intl
Tue 8/18
3:35 am-4:10 pm
2 stops37h 35m
$792
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Tue 3/3
8:20 pm-10:50 pm
2 stops24h 30m
Santa Cruz de la Sierra Viru Viru Intl
Mon 3/9
1:14 am-12:14 pm
1 stop12h 00m
$800
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Wed 6/3
11:59 am-3:31 am
1 stop14h 32m
Santa Cruz de la Sierra Viru Viru Intl
Tue 6/23
1:12 am-8:04 pm
1 stop19h 52m
$804
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Mon 3/2
5:24 pm-2:35 am
2 stops31h 11m
Santa Cruz de la Sierra Viru Viru Intl
Mon 3/9
8:35 am-11:59 pm
1 stop16h 24m
$804
HoustonSanta Cruz de la Sierra
IAH - VVI
IAHVVI
Houston George Bush Intcntl
Sat 5/2
2:05 pm-2:30 am
2 stops35h 25m
Santa Cruz de la Sierra Viru Viru Intl
Tue 5/5
3:35 am-4:10 pm
2 stops13h 35m
$811
Showing 1-10 of 18 results
Best time to book a flight from Houston to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
HO1-VVI
IAH-VVI
HOU-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston to Santa Cruz de la Sierra
HO1-VVI
IAH-VVI
HOU-VVI
What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?
Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $597). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,049). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Houston to Santa Cruz de la Sierra?
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated February 4, 2026.
Read reviews from past customers who have flown United Airlines and Avianca from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Crew
8.1
Overall
7.4
Boarding
7.7
Entertainment
7.1
Food
6.6
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Comfort
7.3
Crew
8.1
Overall
7.4
Boarding
7.7
Entertainment
7.1
Food
6.6
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Comfort
7.3
Crew
8.1
Overall
7.4
Boarding
7.7
Entertainment
7.1
Food
6.6
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Houston to Santa Cruz de la Sierra
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Complete your trip
Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
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Houston and Santa Cruz de la Sierra flights
Browse other Houston and Santa Cruz de la Sierra flight options. Last updated on February 4, 2026.
Popular flight searches
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Top 2 airlines flying from Houston to Santa Cruz de la Sierra
Discover the top 2 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$554 | Average$814 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$726 | Average$1,106 | FlexibilityNo cancel fee | On-time69% |