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Santa Cruz de la Sierra

$321+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Cheap flight deals from Houston to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2025.

Round-trip from

$742
(United Airlines)

One-way from

$321
(Kiwi.com)

Popular in

July

Cheapest in

April

Average price

$1,301
From Houston to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Houston to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 17% potential increase in price ($224 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($50 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Houston to Santa Cruz de la Sierra

Cheapest flights from Houston to Santa Cruz de la Sierra
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:10 pmIAH - VVI
1 stop30h 40mMultiple Airlines
Thu 1/153:40 amVVI - IAH
2 stops34h 57mMultiple Airlines
Deal found 11/3$810
This Avianca deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:30 amIAH - VVI
2 stops17h 05mAvianca
Thu 11/133:40 amVVI - IAH
2 stops13h 30mAvianca
Deal found 11/3$830
This Expedia deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:00 pmIAH - VVI
2 stops35h 35mAvianca
Fri 1/163:40 amVVI - IAH
2 stops13h 30mAvianca
Deal found 11/3$927
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:10 pmIAH - VVI
1 stop30h 40mMultiple Airlines
Mon 1/195:25 amVVI - IAH
2 stops53h 15mMultiple Airlines
Deal found 11/3$940
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:10 pmIAH - VVI
1 stop30h 40mMultiple Airlines
Sat 1/175:25 amVVI - IAH
2 stops28h 45mMultiple Airlines
Deal found 11/3$976
This FlightHub deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:00 pmIAH - VVI
2 stops35h 35mAvianca
Thu 1/153:40 amVVI - IAH
2 stops37h 30mAvianca
Deal found 11/3$985
This Avianca deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:00 pmIAH - VVI
2 stops35h 35mAvianca
Sun 1/183:40 amVVI - IAH
2 stops33h 25mAvianca
Deal found 11/3$1,018
This Avianca deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:00 pmIAH - VVI
2 stops35h 35mAvianca
Wed 1/143:40 amVVI - IAH
2 stops13h 30mAvianca
Deal found 11/3$1,027
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:10 pmIAH - VVI
1 stop30h 40mMultiple Airlines
Sun 1/185:25 amVVI - IAH
2 stops31h 40mMultiple Airlines
Deal found 11/3$1,140
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:00 amIAH - VVI
2 stops20h 36mUnited Airlines
Mon 1/1911:44 amVVI - IAH
2 stops23h 01mUnited Airlines
Deal found 11/3$1,142
This Ovago deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:13 amHOU - VVI
2 stops16h 22mLATAM Airlines
Fri 11/145:25 amVVI - HOU
2 stops34h 03mLATAM Airlines
Deal found 11/3$2,462
This Travelocity deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:25 pmHOU - VVI
2 stops35h 10mLATAM Airlines
Mon 1/55:25 amVVI - HOU
2 stops19h 10mLATAM Airlines
Deal found 11/3$2,469

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.

Fly from

Houston

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Wed 3/4

7:20 am-3:38 am

2 stops18h 18m

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/12

11:42 am-8:21 am

2 stops21h 39m

$742

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sun 3/22

9:41 pm-10:50 pm

2 stops24h 09m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/30

12:15 pm-8:21 am

2 stops21h 06m

$742

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Wed 3/4

7:30 am-3:38 am

2 stops18h 08m

Santa Cruz de la Sierra Viru Viru Intl

Wed 3/11

3:40 am-1:40 pm

1 stop11h 00m

$805

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sun 3/22

5:40 pm-2:35 am

1 stop31h 55m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/30

12:15 pm-8:36 am

2 stops21h 21m

$836

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Fri 11/21

1:00 pm-2:35 am

2 stops35h 35m

Santa Cruz de la Sierra Viru Viru Intl

Fri 1/16

3:40 am-3:10 pm

2 stops13h 30m

$927

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sun 4/19

2:05 pm-1:50 am

2 stops34h 45m

Santa Cruz de la Sierra Viru Viru Intl

Wed 4/22

2:55 am-4:10 pm

2 stops38h 15m

$958

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Fri 11/21

1:00 pm-2:35 am

2 stops35h 35m

Santa Cruz de la Sierra Viru Viru Intl

Sun 1/18

3:40 am-11:05 am

2 stops33h 25m

$1,018

HoustonSanta Cruz de la Sierra

HOU - VVI

HOUVVI

Houston Hobby

Sun 4/19

6:00 am-4:35 am

2 stops21h 35m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/23

5:20 am-9:20 am

2 stops29h 00m

$2,382

HoustonSanta Cruz de la Sierra

HOU - VVI

HOUVVI

Houston Hobby

Sat 12/20

3:25 pm-4:35 am

2 stops35h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 1/5

5:25 am-10:35 pm

2 stops19h 10m

$2,469

HoustonSanta Cruz de la Sierra

HOU - VVI

HOUVVI

Houston Hobby

Fri 11/21

6:00 am-4:35 am

2 stops20h 35m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/17

5:25 am-10:35 pm

2 stops19h 10m

$2,477

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 26 results
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Best time to book a flight from Houston to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santa Cruz de la Sierra

What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $591). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated November 5, 2025.
Read reviews from past customers who have flown United Airlines and Avianca from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,000 reviews

Entertainment

7.1

Boarding

7.7

Overall

7.4

Crew

8.1

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,000 reviews
United Airlines
7.4
Good
9,000 reviews

Entertainment

7.1

Boarding

7.7

Overall

7.4

Crew

8.1

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
Avianca
6.6
Okay
2,471 reviews
United Airlines
7.4
Good
9,000 reviews

Entertainment

7.1

Boarding

7.7

Overall

7.4

Crew

8.1

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Houston?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Houston to Santa Cruz de la Sierra. 2 airlines have flights to Viru Viru Intl from Houston on a regular basis. Booking flights from Houston to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Houston per day.

  • How long is the flight from Houston to Santa Cruz de la Sierra?

    For as low as $742, United Airlines can have you in Santa Cruz de la Sierra from Houston in 18h 18m. There are 3925 mi between Houston and Santa Cruz de la Sierra. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Houston to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Houston to Santa Cruz de la Sierra is Avianca. Our recent data shows that you can find tickets from as low as $586 on this airline. An additional option worth looking into is United Airlines, starting at $726. Avianca is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Houston to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Houston to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Houston to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Houston to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $591). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Houston to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$586Average$874FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$726Average$1,069FlexibilityNo cancel feeOn-time69%

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