Santa Cruz de la Sierra

$404+ Cheap flights from Houston to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — VVI
Apr 29 — May 61
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Cheap flight deals from Houston to Santa Cruz de la Sierra

Cheapest flights from Houston to Santa Cruz de la Sierra
Explore the most affordable flight options available from Houston to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 30, 2026.

This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:39 am
IAH
-
VVI
2 stops13h 51m
Multiple Airlines
Sat 4/183:35 am
VVI
-
IAH
2 stops29h 48m
Multiple Airlines
Deal found 3/30$641
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:40 pm
IAH
-
VVI
2 stops25h 02m
Multiple Airlines
Sun 4/268:35 am
VVI
-
IAH
1 stop24h 48m
Multiple Airlines
Deal found 3/27$748
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:00 pm
IAH
-
VVI
2 stops25h 42m
Multiple Airlines
Mon 4/278:35 am
VVI
-
IAH
1 stop24h 48m
Multiple Airlines
Deal found 3/27$755
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 pm
IAH
-
VVI
2 stops31h 30m
Multiple Airlines
Mon 4/278:35 am
VVI
-
IAH
1 stop24h 48m
Multiple Airlines
Deal found 3/27$758
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 pm
IAH
-
VVI
2 stops27h 42m
Multiple Airlines
Mon 4/278:35 am
VVI
-
IAH
1 stop24h 48m
Multiple Airlines
Deal found 3/27$762
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:39 am
IAH
-
VVI
1 stop16h 11m
Multiple Airlines
Sun 4/268:35 am
VVI
-
IAH
1 stop24h 48m
Multiple Airlines
Deal found 3/27$786
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:39 am
IAH
-
VVI
1 stop16h 11m
Multiple Airlines
Tue 4/2811:48 am
VVI
-
IAH
2 stops21h 35m
Multiple Airlines
Deal found 3/27$789
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:39 am
IAH
-
VVI
1 stop16h 11m
Multiple Airlines
Sun 5/318:35 am
VVI
-
IAH
1 stop29h 50m
Multiple Airlines
Deal found 3/29$804
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:39 am
IAH
-
VVI
1 stop16h 11m
Multiple Airlines
Sat 5/211:47 am
VVI
-
IAH
2 stops21h 36m
Multiple Airlines
Deal found 3/27$810
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 pm
IAH
-
VVI
1 stop33h 50m
Multiple Airlines
Fri 5/11:12 am
VVI
-
IAH
2 stops32h 11m
Multiple Airlines
Deal found 3/28$830
This FlightHub deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:35 pm
HOU
-
VVI
2 stops33h 00m
LATAM Airlines
Wed 11/255:25 am
VVI
-
HOU
2 stops30h 01m
LATAM Airlines
Deal found 3/27$1,882
This KAYAK deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
HOU
-
VVI
2 stops21h 35m
LATAM Airlines
Fri 5/15:25 am
VVI
-
HOU
2 stops29h 28m
LATAM Airlines
Deal found 3/27$2,133

Find flight deals from Houston to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 30, 2026.

Round-trip from

$748
(Kiwi.com)

One-way from

$404
(Kiwi.com)

Popular in

July

Cheapest in

April

Average price

$766
From Houston to Santa Cruz de la Sierra Viru Viru Intl
One-way flight from Houston to Santa Cruz de la Sierra Viru Viru Intl
Highest demand for flights based on searches. 15% potential increase in price ($170 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($54 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Fri 4/17

8:50 pm-2:30 am

2 stops28h 40m

Santa Cruz de la Sierra Viru Viru Intl

Sun 4/19

8:35 am-8:23 am

1 stop24h 48m

$758
Quickest round-trip

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Thu 4/30

11:39 am-4:50 am

1 stop16h 11m

Santa Cruz de la Sierra Viru Viru Intl

Thu 5/21

11:47 am-11:42 am

2 stops24h 55m

$812

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Tue 5/12

6:39 pm-3:31 am

2 stops31h 52m

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/19

11:47 am-8:49 pm

2 stops34h 02m

$843

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sat 4/25

4:30 pm-3:40 am

2 stops34h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

11:47 am-8:29 am

2 stops21h 42m

$893

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Fri 4/10

5:45 pm-2:30 am

2 stops31h 45m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/13

3:35 am-12:05 pm

2 stops33h 30m

$901

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Mon 4/20

2:05 pm-2:30 am

2 stops35h 25m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/23

3:35 am-12:05 pm

2 stops33h 30m

$901

HoustonSanta Cruz de la Sierra

IAH - VVI

IAHVVI

Houston George Bush Intcntl

Sat 5/23

2:05 pm-2:30 am

2 stops35h 25m

Santa Cruz de la Sierra Viru Viru Intl

Mon 7/27

3:35 am-9:15 am

3 stops30h 40m

$995

HoustonSanta Cruz de la Sierra

HOU - VVI

HOUVVI

Houston Hobby

Sun 4/19

6:00 am-4:35 am

2 stops21h 35m

Santa Cruz de la Sierra Viru Viru Intl

Fri 5/1

5:25 am-9:53 am

2 stops29h 28m

$2,133

HoustonSanta Cruz de la Sierra

HOU - VVI

HOUVVI

Houston Hobby

Wed 4/22

10:53 am-4:35 am

2 stops16h 42m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

5:25 am-9:58 am

2 stops29h 33m

$2,249

HoustonSanta Cruz de la Sierra

HOU - VVI

HOUVVI

Houston Hobby

Thu 4/23

10:53 am-4:35 am

2 stops16h 42m

Santa Cruz de la Sierra Viru Viru Intl

Fri 5/1

5:25 am-9:53 am

2 stops29h 28m

$2,249

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Houston to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santa Cruz de la Sierra

What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $586). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Houston to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated March 30, 2026.
Read reviews from past customers who have flown Copa Airlines,United Airlines, andAvianca from Houston to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

6.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.5

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Food

6.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.5

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Food

6.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.5

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Food

6.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.5

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Houston to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santa Cruz de la Sierra from Houston?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Houston to Santa Cruz de la Sierra. 3 airlines have flights to Viru Viru Intl from Houston on a regular basis. Booking flights from Houston to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Houston per day.

  • How long is the flight from Houston to Santa Cruz de la Sierra?

    For as low as $901, United Airlines can have you in Santa Cruz de la Sierra from Houston in 31h 45m. There are 3925 mi between Houston and Santa Cruz de la Sierra. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Houston to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Houston to Santa Cruz de la Sierra is Avianca. Our recent data shows that you can find tickets from as low as $586 on this airline. Additional options worth looking into are Copa Airlines and United Airlines, starting at $709 and $726 round-trip. Avianca is priced at 38% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Houston to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Houston to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Houston to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Houston to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from Houston to Santa Cruz de la Sierra (average of $586). Flying from Houston to Santa Cruz de la Sierra in January is currently the most expensive (average of $1,177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Houston to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Houston to Santa Cruz de la Sierra

Discover the top 3 airlines that operate flights from Houston to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$586Average$830FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$709Average$1,328FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$726Average$1,124FlexibilityNo cancel feeOn-time69%

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