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Santa Cruz de la Sierra

$808+ Cheap flights from Frankfurt (FRA) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — VVI
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Frankfurt to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$1,209
(United Airlines)

One-way from

$808
(United Airlines)

Popular in

December

Cheapest in

March

Average price

$1,184
From Frankfurt am Main to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Frankfurt am Main to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 14% potential increase in price ($215 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($60 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Frankfurt to Santa Cruz de la Sierra

Cheapest flights from Frankfurt to Santa Cruz de la Sierra
Explore the most affordable flight options available from Frankfurt to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/285:10 pmFRA - VVI
2 stops59h 15mUnited Airlines
Tue 10/141:09 amVVI - FRA
2 stops26h 46mUnited Airlines
Deal found 9/15$1,209
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:40 amFRA - VVI
2 stops43h 00mUnited Airlines
Fri 11/211:09 amVVI - FRA
2 stops49h 31mUnited Airlines
Deal found 9/16$1,210
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/61:50 pmFRA - VVI
2 stops38h 50mUnited Airlines
Mon 10/201:09 amVVI - FRA
2 stops48h 11mUnited Airlines
Deal found 9/15$1,325
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:10 pmFRA - VVI
2 stops59h 30mUnited Airlines
Tue 11/111:09 amVVI - FRA
2 stops49h 01mUnited Airlines
Deal found 9/14$1,326
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/610:30 amFRA - VVI
2 stops42h 10mUnited Airlines
Tue 10/211:09 amVVI - FRA
2 stops26h 46mUnited Airlines
Deal found 9/16$1,331
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/101:10 pmFRA - VVI
2 stops39h 30mUnited Airlines
Sat 10/181:09 amVVI - FRA
2 stops26h 46mUnited Airlines
Deal found 9/15$1,414
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/291:50 pmFRA - VVI
2 stops38h 35mUnited Airlines
Thu 11/131:09 amVVI - FRA
2 stops49h 01mUnited Airlines
Deal found 9/14$1,415
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2212:50 pmFRA - VVI
2 stops62h 56mUnited Airlines
Wed 12/101:09 amVVI - FRA
2 stops31h 51mUnited Airlines
Deal found 9/15$1,473
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/310:30 amFRA - VVI
2 stops42h 10mUnited Airlines
Fri 11/141:09 amVVI - FRA
2 stops49h 01mUnited Airlines
Deal found 9/14$1,532
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:50 pmFRA - VVI
2 stops63h 00mUnited Airlines
Sun 3/291:14 amVVI - FRA
2 stops48h 46mUnited Airlines
Deal found 9/15$1,590
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:25 pmFRA - VVI
2 stops58h 25mUnited Airlines
Mon 2/91:15 amVVI - FRA
2 stops48h 55mUnited Airlines
Deal found 9/14$1,591
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:10 pmFRA - VVI
2 stops58h 36mUnited Airlines
Wed 12/101:09 amVVI - FRA
2 stops49h 31mUnited Airlines
Deal found 9/15$1,620

Cheapflights Fare Finder

 
Customize your flight search to find flights from Frankfurt to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Santa Cruz de la Sierra that are best for you.

Fly from

Frankfurt

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Wed 10/1

12:20 pm-10:40 pm

2 stops40h 20m

Santa Cruz de la Sierra Viru Viru Intl

Sun 11/9

1:09 am-9:55 am

2 stops51h 46m

$1,209

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Tue 2/24

1:20 pm-10:50 pm

2 stops38h 30m

Santa Cruz de la Sierra Viru Viru Intl

Fri 3/13

1:14 am-7:40 am

2 stops25h 26m

$1,209

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Sat 10/4

12:20 pm-10:40 pm

2 stops40h 20m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/8

1:09 am-9:20 am

2 stops51h 11m

$1,209

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Wed 10/1

5:10 pm-10:40 pm

2 stops35h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/10

1:09 am-11:50 am

2 stops53h 41m

$1,209

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Sat 10/4

12:20 pm-10:40 pm

2 stops40h 20m

Santa Cruz de la Sierra Viru Viru Intl

Wed 11/12

1:09 am-2:55 pm

2 stops56h 46m

$1,209

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Wed 10/29

8:40 am-10:40 pm

2 stops43h 00m

Santa Cruz de la Sierra Viru Viru Intl

Fri 11/21

1:09 am-7:40 am

2 stops49h 31m

$1,210

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Mon 11/3

5:15 pm-10:46 pm

2 stops34h 31m

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/17

1:09 am-9:10 am

2 stops27h 01m

$1,210

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Wed 11/5

11:30 am-10:46 pm

2 stops40h 16m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/15

1:09 am-7:25 am

2 stops25h 16m

$1,210

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Thu 10/2

5:10 pm-10:40 pm

2 stops59h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/8

1:09 am-11:50 am

2 stops53h 41m

$1,326

Frankfurt am MainSanta Cruz de la Sierra

FRA - VVI

FRAVVI

Frankfurt am Main

Thu 10/2

5:10 pm-10:40 pm

2 stops59h 30m

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/11

1:09 am-7:10 am

2 stops49h 01m

$1,326

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 16 results
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Best time to book a flight from Frankfurt to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Frankfurt with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Santa Cruz de la Sierra

How far ahead should I book a flight from Frankfurt am Main Airport to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Frankfurt to Santa Cruz de la Sierra. Price data was last updated on September 12, 2025.

The price you pay for your flight from Frankfurt am Main Airport to Santa Cruz de la Sierra may vary depending on when you book. For the best chance of a lower fare, look to book 64 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Frankfurt am Main Airport to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Santa Cruz de la Sierra (average of $597). Flying from Frankfurt am Main Airport to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Frankfurt am Main Airport to Santa Cruz de la Sierra?

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Frankfurt am Main?

    For a flight from Frankfurt am Main to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city. Viru Viru Intl is the only Santa Cruz de la Sierra airport and it handles 0 inbound flights from Frankfurt am Main per day. 0 airlines have flights to Santa Cruz de la Sierra Viru Viru Intl from Frankfurt am Main on a regular basis.

  • How long is the flight from Frankfurt am Main Airport to Santa Cruz de la Sierra?

    A quick flight from Frankfurt am Main Airport to Santa Cruz de la Sierra can take about 38h 45m. United Airlines provides one of the quickest options available for as low as $1,209. Airlines will cover a distance of 6373 mi.

  • Can I find deals for flights from Frankfurt to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Frankfurt to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Frankfurt to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Santa Cruz de la Sierra (average of $597). Flying from Frankfurt am Main Airport to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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