$166+ Cheap flights from McAllen to San Francisco (MFE - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — SFO
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from McAllen to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from McAllen to San Francisco
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Cheapest flights from McAllen to San FranciscoExplore the most affordable flight options available from McAllen to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from McAllen to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:38 pm -
2 stops14h 33m
Tue 11/103:05 pm -
1 stop22h 58m
Deal found 9/19![Multiple Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:36 pm -
1 stop8h 03m
Sat 11/71:57 pm -
1 stop7h 19m
Deal found 9/15![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:28 pm -
1 stop8h 19m
Sat 12/54:00 pm -
1 stop5h 48m
Deal found 9/17![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:36 pm -
1 stop8h 03m
Sun 11/86:38 am -
1 stop9h 05m
Deal found 9/15![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:46 pm -
2 stops13h 10m
Sat 11/710:55 am -
1 stop5h 28m
Deal found 9/15![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:35 pm -
1 stop9h 14m
Wed 10/75:30 am -
1 stop8h 04m
Deal found 9/18![American Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:39 pm -
2 stops11h 00m
Wed 10/712:05 pm -
2 stops9h 54m
Deal found 9/18![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:28 pm -
1 stop8h 19m
Mon 11/234:00 pm -
1 stop5h 48m
Deal found 9/17![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:35 pm -
1 stop8h 53m
Sat 9/196:36 am -
1 stop6h 51m
Deal found 9/16![American Airlines logo]()
$427
Best flights from McAllen to San FranciscoDiscover carefully curated flight deals from McAllen to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from McAllen to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:38 pm -
2 stops14h 33m
Tue 11/103:05 pm -
1 stop22h 58m
Deal found 9/19![Multiple Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:36 pm -
1 stop8h 03m
Sat 11/71:57 pm -
1 stop7h 19m
Deal found 9/15![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:46 pm -
2 stops13h 10m
Sat 11/710:55 am -
1 stop5h 28m
Deal found 9/15![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:40 am -
1 stop7h 09m
Sun 10/412:45 am -
1 stop6h 08m
Deal found 9/15![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:12 pm -
1 stop7h 37m
Sun 10/412:11 am -
1 stop6h 42m
Deal found 9/17![American Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:20 am -
1 stop5h 34m
Mon 10/59:55 pm -
2 stops12h 11m
Deal found 9/15![Delta logo]()
$454
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:39 pm -
2 stops10h 55m
Mon 10/511:30 pm -
2 stops13h 52m
Deal found 9/18![Delta logo]()
$459
Last-minute flights from McAllen to San FranciscoDiscover last-minute flight deals from McAllen to San Francisco. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from McAllen to San Francisco. Data last updated September 21, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:20 am -
1 stop5h 34m
Mon 10/59:55 pm -
2 stops12h 11m
Deal found 9/17![Delta logo]()
$454
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:40 am -
1 stop7h 09m
Sun 10/412:45 am -
1 stop6h 08m
Deal found 9/15![United Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:17 pm -
2 stops8h 23m
Mon 10/59:55 pm -
2 stops12h 11m
Deal found 9/15![Delta logo]()
$459
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:35 pm -
1 stop9h 14m
Wed 10/75:30 am -
1 stop8h 04m
Deal found 9/18![American Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:39 pm -
2 stops11h 00m
Wed 10/712:05 pm -
2 stops9h 54m
Deal found 9/18![Delta logo]()
$377
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:20 am -
1 stop8h 24m
Tue 10/67:05 am -
1 stop6h 54m
Deal found 9/15![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:46 pm -
2 stops13h 10m
Sat 10/107:10 am -
2 stops9h 13m
Deal found 9/17![Delta logo]()
$447
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:20 am -
1 stop7h 22m
Mon 10/1912:45 am -
1 stop8h 37m
Deal found 9/19![United Airlines logo]()
$469
One-way flights from McAllen to San FranciscoSearch for one-way flight options from McAllen to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from McAllen to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:31 pm -
1 stop11h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:31 pm -
2 stops24h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$206
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:46 pm -
1 stop6h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Delta logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:55 pm -
1 stop13h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$230
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:46 pm -
2 stops11h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Delta logo]()
$239
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:02 pm -
2 stops9h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Delta logo]()
$295
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:20 am -
1 stop6h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![United Airlines logo]()
$380
Find flight deals from McAllen to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from McAllen (MFE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (Kiwi.com) |
One-way from | $166 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $395 |
Cheapflights Fare Finder
Customize your flight search to find flights from McAllen to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from McAllen to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Fri 10/16
10:31 pm-8:38 pm
2 stops24h 07m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$206
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Fri 10/23
12:46 pm-5:33 pm
1 stop6h 47m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$224
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Fri 10/9
4:02 pm-11:58 pm
2 stops9h 56m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$295
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Sun 11/8
9:38 pm-10:11 am
2 stops14h 33m
San Francisco
Tue 11/10
3:05 pm-4:03 pm
1 stop22h 58m
$299
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Wed 11/4
6:36 pm-12:39 am
1 stop8h 03m
San Francisco
Sat 11/7
1:57 pm-11:16 pm
1 stop7h 19m
$329
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Wed 11/4
12:46 pm-11:56 pm
2 stops13h 10m
San Francisco
Sat 11/7
10:55 am-6:23 pm
1 stop5h 28m
$354
Quickest round-trip
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Sat 10/10
5:20 am-9:30 am
1 stop6h 10m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$380
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Fri 10/9
7:24 pm-11:47 pm
1 stop6h 23m
San Francisco
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$439
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Fri 10/2
9:40 am-2:49 pm
1 stop7h 09m
San Francisco
Sun 10/4
12:45 am-8:53 am
1 stop6h 08m
$449
McAllenSan Francisco
MFE McAllen Miller Intl - SFO San Francisco
MFESFO
McAllen Miller Intl
Thu 10/1
6:12 pm-11:49 pm
1 stop7h 37m
San Francisco
Sun 10/4
12:11 am-8:53 am
1 stop6h 42m
$449
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from McAllen to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from McAllen to San Francisco in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on McAllen-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on McAllen-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from McAllen-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on McAllen-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for McAllen-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from McAllen to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from McAllen with our price prediction graph.
MFE-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from McAllen to San Francisco
What is the cheapest month to book a flight from McAllen to San Francisco?
Currently, January is the cheapest month in which you can book a flight from McAllen to San Francisco (average of $236). Flying from McAllen to San Francisco in June is currently the most expensive (average of $595). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from McAllen to San Francisco?
Airfare is below average for this route at the moment.
McAllen to San Francisco flights typically cost between $300 and $480 in November.The cheapest round-trip price found within the last 5 days was $299 on Multiple Airlines (Nov 8-Nov 10).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 21, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from McAllen to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Boarding
7.7
Food
6.7
Entertainment
7.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
10.0
ExcellentKathy,Jun 2024
RDD - SFO
Crew
8.1
Boarding
7.7
Food
6.7
Entertainment
7.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
10.0
ExcellentKathy,Jun 2024
RDD - SFO
Crew
8.1
Boarding
7.7
Food
6.7
Entertainment
7.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
10.0
ExcellentKathy,Jun 2024
RDD - SFO
Related info for your journey
Find useful and relevant information for your journey from McAllen to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Emeryville
Burlingame
Rancho Cordova
San Bruno
Roseville
Hayward
Cupertino
Newark
Fairfield
San Ramon
Redwood City
Manteca
Vallejo
San Carlos
Turlock
Davis
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McAllen and San Francisco flights
Browse other McAllen and San Francisco flight options. Last updated on September 21, 2026.
Other flights from McAllen
Browse through other flights departing from McAllen. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
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Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Top 2 airlines flying from McAllen to San Francisco
Discover the top 2 airlines that operate flights from McAllen to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$246 | Average$395 | FlexibilityNo cancel fee | On-time69% |