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$507+ Cheap flights from Panama City, FL (ECP) to Prague (PRG)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — PRG
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Panama City to Prague

Cheapest flights from Panama City to Prague
Explore the most affordable flight options available from Panama City to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:03 am
ECP
-
PRG
2 stops26h 02m
Delta
Sun 3/16:00 am
PRG
-
ECP
2 stops23h 39m
Delta
Deal found 1/26$507
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:01 pm
ECP
-
PRG
2 stops26h 24m
United Airlines
Mon 2/2310:25 am
PRG
-
ECP
2 stops18h 31m
United Airlines
Deal found 1/25$710
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:14 pm
ECP
-
PRG
2 stops19h 31m
American Airlines
Wed 8/196:30 am
PRG
-
ECP
2 stops18h 45m
American Airlines
Deal found 1/26$719
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:28 pm
ECP
-
PRG
2 stops19h 32m
American Airlines
Tue 6/98:40 am
PRG
-
ECP
2 stops20h 54m
American Airlines
Deal found 1/25$783

Find flight deals from Panama City to Prague

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Prague (PRG). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$507
(Delta)
Provider with most accurate pricing for Panama City NW Florida Beaches-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Václav Havel Prague flights.
Search Deals
From Panama City NW Florida Beaches to Václav Havel Prague
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Panama City to Prague that are best for you.

Fly from

Panama City

Fly to

Prague

Route

Depart

Return

Price

Panama CityPrague

ECP - PRG

ECPPRG

Panama City NW Florida Beaches

Mon 2/23

8:03 am-5:05 pm

2 stops26h 02m

Václav Havel Prague

Sun 3/1

6:00 am-10:39 pm

2 stops23h 39m

$507

Panama CityPrague

ECP - PRG

ECPPRG

Panama City NW Florida Beaches

Thu 2/19

6:30 am-4:05 pm

2 stops26h 35m

Václav Havel Prague

Mon 2/23

10:25 am-9:56 pm

2 stops18h 31m

$710

Panama CityPrague

ECP - PRG

ECPPRG

Panama City NW Florida Beaches

Wed 6/10

1:14 pm-3:45 pm

2 stops19h 31m

Václav Havel Prague

Wed 8/19

6:30 am-6:15 pm

2 stops18h 45m

$719

Panama CityPrague

ECP - PRG

ECPPRG

Panama City NW Florida Beaches

Mon 6/1

2:28 pm-5:00 pm

2 stops19h 32m

Václav Havel Prague

Tue 6/9

8:40 am-10:34 pm

2 stops20h 54m

$783

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

  • Most accurate provider: When it comes to deals on Panama City, Florida-Prague flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Prague flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Prague flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Prague flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Prague flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Prague

What is the cheapest month to book a flight from Panama City, Florida to Prague?

Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Prague (average of $480). Flying from Panama City, Florida to Prague in June is currently the most expensive (average of $1,450). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Prague

Get insights into the airlines that provide service to Prague. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Prague. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with American Airlines from Panama City to Prague by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,197 reviews

Crew

8.0

Food

6.4

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.
American Airlines
7.2
Good
11,197 reviews
American Airlines
7.2
Good
11,197 reviews

Crew

8.0

Food

6.4

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Prague?

    A quick flight from Panama City, Florida to Prague can take about 19h 31m. Delta provides one of the quickest options available for as low as $719. Airlines will cover a distance of 5046 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Panama City, Florida to Prague round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Prague round-trip from $624.

  • Can I find deals for flights from Panama City to Prague that include hotel bookings?

    Yes. In addition to deals on Panama City to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Prague.

  • Can I find deals for business class flights from Panama City to Prague?

    Yes. Cheapflights offers flight deals from Panama City to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Prague?

    Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Prague (average of $480). Flying from Panama City, Florida to Prague in June is currently the most expensive (average of $1,450). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to Prague

Discover the top airline that operate flights from Panama City to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$624Average$626FlexibilityNo cancel feeOn-time71%

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