Panama

$199+ Cheap flights from Medford (MFR) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/3. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — PTY
Jan 27 — Feb 31
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Medford to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Medford to Panama

Best flights from Medford to Panama
Discover carefully curated flight deals from Medford to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:00 pmMFR - PTY
2 stops26h 38mUnited Airlines
Tue 3/34:41 pmPTY - MFR
2 stops21h 15mUnited Airlines
Deal found 12/25$453
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/102:00 pmMFR - PTY
2 stops24h 07mUnited Airlines
Tue 2/174:41 pmPTY - MFR
2 stops21h 15mUnited Airlines
Deal found 12/27$483
This Expedia deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:20 amMFR - PTY
3 stops29h 35mMultiple Airlines
Tue 2/173:50 pmPTY - MFR
2 stops26h 11mMultiple Airlines
Deal found 12/27$1,062
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/103:00 pmMFR - PTY
3 stops19h 27mAmerican Airlines
Tue 2/172:50 pmPTY - MFR
3 stops25h 44mAmerican Airlines
Deal found 12/27$2,576

Find flight deals from Medford to Panama

Keep the following information in mind while searching for Medford to Panama flight deals. Data was last updated December 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$453
(United Airlines)

One-way from

$199
(United Airlines)
Provider with most accurate pricing for Medford-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Medford-Panama City Tocumen Intl flights.
From Medford to Panama
One-way flight from Medford to Panama

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Medford to Panama that are best for you.

Fly from

Medford

Fly to

Panama

Route

Depart

Return

Price

MedfordPanama City

MFR - PTY

MFRPTY

Medford

Sat 2/28

2:00 pm-7:38 pm

2 stops26h 38m

Panama City Tocumen Intl

Tue 3/3

4:41 pm-10:56 am

2 stops21h 15m

$453

MedfordPanama City

MFR - PTY

MFRPTY

Medford

Tue 2/10

2:00 pm-5:07 pm

2 stops24h 07m

Panama City Tocumen Intl

Tue 2/17

4:41 pm-10:56 am

2 stops21h 15m

$483

MedfordPanama City

MFR - PTY

MFRPTY

Medford

Tue 2/10

6:20 am-2:55 pm

3 stops29h 35m

Panama City Tocumen Intl

Tue 2/17

3:50 pm-3:01 pm

2 stops26h 11m

$1,062

MedfordPanama City

MFR - PTY

MFRPTY

Medford

Tue 2/10

3:00 pm-1:27 pm

3 stops19h 27m

Panama City Tocumen Intl

Tue 2/17

2:50 pm-1:34 pm

3 stops25h 44m

$2,576

MedfordPanama City

MFR - PTY

MFRPTY

Medford

Sat 1/3

6:34 pm-2:45 pm

2 stops17h 11m

$199

MedfordPanama City

MFR - PTY

MFRPTY

Medford

Sat 1/3

5:07 am-10:30 am

3 stops26h 23m

$616

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Best time to book a flight from Medford to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Panama
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 28, 2025.
Peruse reviews from past customers who have flown with United Airlines from Medford to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Medford to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Medford to Panama?

    Medford (MFR) is the airport you will fly out of if you book a flight from Medford to Panama. It is only a 3.0 mi journey to Medford (MFR) from Medford’s city center.

  • How long is the flight from Medford to Panama?

    Departing from Medford to Panama will take you 26h 38m. The distance between Medford and Panama is about 3489 mi.

  • Can I find deals for flights from Medford to Panama that include hotel bookings?

    Yes. In addition to deals on Medford to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Panama.

  • Can I find deals for business class flights from Medford to Panama?

    Yes. Cheapflights offers flight deals from Medford to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Medford to Panama

Discover the top airline that operate flights from Medford to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$387Average$519FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.