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$226+ Cheap flights from Manchester, NH (MHT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — PTY
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Cheap flight deals from Manchester to Panama

Keep the following information in mind while searching for Manchester to Panama flight deals. Data was last updated October 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$522
(United Airlines)

One-way from

$226
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$530
Provider with most accurate pricing for Boston Logan Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Boston Logan Intl-Panama City Tocumen Intl flights.
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From Manchester to Panama
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One-way flight from Manchester to Panama
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Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Manchester to Panama

Cheapest flights from Manchester to Panama
Explore the most affordable flight options available from Manchester to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/159:30 amMHT - PTY
2 stops29h 15mUnited Airlines
Wed 11/198:55 amPTY - MHT
2 stops14h 49mUnited Airlines
Deal found 10/22$522
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/92:27 pmMHT - PTY
2 stops29h 11mUnited Airlines
Thu 11/138:55 amPTY - MHT
2 stops14h 49mUnited Airlines
Deal found 10/20$539
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/184:04 pmMHT - PTY
2 stops21h 45mAmerican Airlines
Fri 11/212:43 pmPTY - MHT
2 stops24h 53mAmerican Airlines
Deal found 10/22$582
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:00 amMHT - PTY
2 stops9h 54mAmerican Airlines
Mon 1/124:46 pmPTY - MHT
2 stops18h 47mAmerican Airlines
Deal found 10/21$923
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:26 pmMHT - PTY
1 stop18h 05mUnited Airlines
Mon 1/129:11 amPTY - MHT
1 stop9h 40mUnited Airlines
Deal found 10/20$5,449

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Manchester to Panama that are best for you.

Fly from

Manchester

Fly to

Panama

Route

Depart

Return

Price

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sun 11/9

9:30 am-2:45 pm

2 stops29h 15m

Panama City Tocumen Intl

Thu 11/13

8:55 am-11:44 pm

2 stops14h 49m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 11/15

9:30 am-2:45 pm

2 stops29h 15m

Panama City Tocumen Intl

Wed 11/19

8:55 am-11:44 pm

2 stops14h 49m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Thu 12/4

7:27 pm-5:07 pm

2 stops21h 40m

Panama City Tocumen Intl

Thu 12/11

4:41 pm-6:49 pm

2 stops26h 08m

$522

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Tue 11/18

4:04 pm-1:49 pm

2 stops21h 45m

Panama City Tocumen Intl

Fri 11/21

2:43 pm-3:36 pm

2 stops24h 53m

$582

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 2/13

7:28 pm-5:07 pm

2 stops21h 39m

Panama City Tocumen Intl

Sat 2/21

4:41 pm-6:53 pm

2 stops26h 12m

$614

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Fri 12/19

6:00 am-3:54 pm

2 stops9h 54m

Panama City Tocumen Intl

Mon 1/12

4:46 pm-11:33 am

2 stops18h 47m

$923

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Mon 3/16

7:28 pm-1:45 pm

2 stops19h 17m

$226

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Tue 3/17

7:28 pm-4:07 pm

2 stops21h 39m

$226

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sun 3/15

7:28 pm-1:45 pm

2 stops19h 17m

$232

ManchesterPanama City

MHT - PTY

MHTPTY

Manchester

Sat 3/14

7:28 pm-6:38 pm

2 stops24h 10m

$232

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 11 results
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Best time to book a flight from Manchester to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Panama

What is the cheapest month to book a flight from Manchester, New Hampshire to Panama?

Currently, September is the cheapest month in which you can book a flight from Manchester, New Hampshire to Panama (average of $402). Flying from Manchester, New Hampshire to Panama in March is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Panama?

    Manchester (MHT), located 4.8 mi from the city center, is the airport you fly out of when you book flights from Manchester to Panama.

  • How long is the flight from Manchester, New Hampshire to Panama?

    Airlines like United Airlines fly from Manchester, New Hampshire to Panama in about 29h 15m. The time it takes to get you to your destination can typically vary by up to . The distance between Manchester, New Hampshire and Panama is about 2386 mi.

  • Can I find deals for flights from Manchester to Panama that include hotel bookings?

    Yes. In addition to deals on Manchester to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Panama.

  • Can I find deals for business class flights from Manchester to Panama?

    Yes. Cheapflights offers flight deals from Manchester to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Panama?

    Currently, September is the cheapest month in which you can book a flight from Manchester, New Hampshire to Panama (average of $402). Flying from Manchester, New Hampshire to Panama in March is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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