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Panama

$154+ Cheap flights from Houston to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — PTY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Houston to Panama

Cheapest flights from Houston to Panama
Explore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/273:54 pmIAH - PTY
2 stops15h 56mMultiple Airlines
Thu 12/45:50 pmPTY - IAH
2 stops14h 14mMultiple Airlines
Deal found 10/28$362
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:35 pmIAH - PTY
1 stop10h 55mMultiple Airlines
Thu 11/2010:47 amPTY - IAH
1 stop9h 18mMultiple Airlines
Deal found 10/27$402
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:25 pmIAH - PTY
2 stops19h 35mMultiple Airlines
Mon 12/87:50 pmPTY - IAH
2 stops21h 18mMultiple Airlines
Deal found 10/29$409
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:35 pmIAH - PTY
1 stop10h 55mMultiple Airlines
Sat 11/228:25 amPTY - IAH
1 stop8h 04mMultiple Airlines
Deal found 10/27$411
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:35 pmIAH - PTY
1 stop10h 31mMultiple Airlines
Sat 11/228:25 amPTY - IAH
1 stop8h 04mMultiple Airlines
Deal found 10/28$412
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:35 pmIAH - PTY
1 stop10h 31mMultiple Airlines
Tue 11/2510:47 amPTY - IAH
1 stop9h 18mMultiple Airlines
Deal found 10/28$413
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:35 pmIAH - PTY
1 stop10h 31mMultiple Airlines
Wed 11/2610:47 amPTY - IAH
1 stop8h 55mMultiple Airlines
Deal found 10/28$422
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:10 pmIAH - PTY
2 stops21h 45mMultiple Airlines
Wed 12/1011:25 amPTY - IAH
2 stops12h 13mMultiple Airlines
Deal found 10/28$424
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/711:02 amIAH - PTY
1 stop7h 18mMultiple Airlines
Fri 11/2110:47 amPTY - IAH
1 stop8h 55mMultiple Airlines
Deal found 10/28$426
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/287:37 pmIAH - PTY
1 stop11h 29mMultiple Airlines
Fri 12/510:25 amPTY - IAH
1 stop14h 34mMultiple Airlines
Deal found 10/29$428
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:22 pmHOU - PTY
2 stops18h 21mAmerican Airlines
Fri 12/54:43 pmPTY - HOU
2 stops17h 55mAmerican Airlines
Deal found 10/29$777
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:25 pmHOU - PTY
2 stops20h 18mAmerican Airlines
Mon 12/84:43 pmPTY - HOU
2 stops17h 55mAmerican Airlines
Deal found 10/29$778

Cheap flight deals from Houston to Panama

Keep the following information in mind while searching for Houston to Panama flight deals. Data was last updated October 30, 2025.

Round-trip from

$362
(Mytrip)

One-way from

$154
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$913
From Houston to Panama
Search Deals
One-way flight from Houston to Panama
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Houston to Panama that are best for you.

Fly from

Houston

Fly to

Panama

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 1/7

9:30 am-6:55 pm

1 stop8h 25m

Panama City Tocumen Intl

Tue 1/13

3:50 pm-4:57 pm

1 stop26h 07m

$522

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 1/6

9:30 am-6:55 pm

1 stop8h 25m

Panama City Tocumen Intl

Sun 1/11

3:50 pm-4:57 pm

1 stop26h 07m

$546

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 12/10

8:00 am-7:20 pm

1 stop10h 20m

Panama City Tocumen Intl

Wed 1/7

7:50 pm-6:36 pm

2 stops23h 46m

$560

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Fri 1/2

9:30 am-6:55 pm

1 stop8h 25m

Panama City Tocumen Intl

Tue 1/13

3:50 pm-4:57 pm

1 stop26h 07m

$563

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Sat 1/3

9:30 am-6:55 pm

1 stop8h 25m

Panama City Tocumen Intl

Tue 1/13

3:50 pm-4:57 pm

1 stop26h 07m

$563

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 11/11

8:35 pm-8:50 am

2 stops11h 15m

Panama City Tocumen Intl

Fri 11/21

11:25 am-12:41 am

2 stops14h 16m

$573

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Sat 11/8

8:35 pm-4:55 pm

2 stops19h 20m

Panama City Tocumen Intl

Sat 11/15

11:25 am-12:18 am

2 stops13h 53m

$578

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 11/3

3:13 pm-10:30 am

2 stops18h 17m

Panama City Tocumen Intl

Mon 11/10

9:45 am-1:17 pm

2 stops28h 32m

$589

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 1/7

9:30 am-6:55 pm

1 stop8h 25m

Panama City Tocumen Intl

Thu 1/15

3:50 pm-4:57 pm

1 stop26h 07m

$615

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Fri 12/26

10:44 am-7:55 pm

1 stop8h 11m

Panama City Tocumen Intl

Wed 12/31

7:31 am-5:40 pm

1 stop11h 09m

$622

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 48 results
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Best time to book a flight from Houston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Panama

What is the cheapest month to book a flight from Houston to Panama?

Currently, January is the cheapest month in which you can book a flight from Houston to Panama (average of $324). Flying from Houston to Panama in April is currently the most expensive (average of $744). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to PA?

Find hourly flight availability from Houston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

One of the essential ways to save on airfare from Houston to Panama is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 77% on airfare.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, United Airlines, and Avianca from Houston to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,563 reviews

Comfort

7.4

Boarding

7.8

Food

6.8

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,563 reviews
Copa Airlines
7.6
Good
1,563 reviews

Comfort

7.4

Boarding

7.8

Food

6.8

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
United Airlines
7.4
Good
8,998 reviews
Copa Airlines
7.6
Good
1,563 reviews

Comfort

7.4

Boarding

7.8

Food

6.8

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.6
Okay
2,467 reviews
Copa Airlines
7.6
Good
1,563 reviews

Comfort

7.4

Boarding

7.8

Food

6.8

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Houston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Houston to Panama?

    There are many flights that can get you from Houston to Panama in 7h 20m. Fly via Delta or American Airlines to get the fastest option. There are 1753 mi between Houston and Panama. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Houston to Panama?

    Most travelers choose Houston Hobby - Panama City Tocumen Intl, Houston George Bush Intcntl - Panama City Tocumen Intl or Houston George Bush Intcntl - Bocas Del Toro when deciding on the best route from Houston to Panama.

  • Can I find deals for flights from Houston to Panama that include hotel bookings?

    Yes. In addition to deals on Houston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Panama.

  • Can I find deals for business class flights from Houston to Panama?

    Yes. Cheapflights offers flight deals from Houston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Panama?

    Currently, January is the cheapest month in which you can book a flight from Houston to Panama (average of $324). Flying from Houston to Panama in April is currently the most expensive (average of $744). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Houston to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Hobby to San Salvador flights
Dallas/Fort Worth to San Salvador flights
George Bush Intcntl to San Salvador flights
Hobby to San José flights
Hobby to Panama City flights
Dallas/Fort Worth to San José flights
George Bush Intcntl to San José flights
Hobby to San Pedro Sula flights
George Bush Intcntl to San Pedro Sula flights
Hobby to Philip S.W.Goldson flights
Dallas/Fort Worth to Panama City flights
Dallas/Fort Worth to Guatemala City flights
Hobby to Guatemala City flights
George Bush Intcntl to Panama City flights
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George Bush Intcntl to Guatemala City flights
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Hobby to Liberia flights
Dallas/Fort Worth to Liberia flights
Hobby to Managua flights
Austin to San José flights
Dallas/Fort Worth to San Pedro Sula flights
George Bush Intcntl to Liberia flights
George Bush Intcntl to Managua flights
Love Field to San José flights
Austin to Liberia flights
Austin to Panama City flights
Love Field to Philip S.W.Goldson flights
Austin to Philip S.W.Goldson flights
Dallas/Fort Worth to Managua flights
San Antonio to Panama City flights
Hobby to Coxen Hole flights
San Antonio to San José flights
George Bush Intcntl to Coxen Hole flights
Austin to San Salvador flights
Love Field to San Salvador flights
Austin to Guatemala City flights
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Love Field to Guatemala City flights
San Antonio to Managua flights
San Antonio to San Salvador flights
El Paso to San José flights
Austin to San Pedro Sula flights
San Antonio to Philip S.W.Goldson flights
McAllen to San José flights

Top 3 airlines flying from Houston to Panama

Discover the top 3 airlines that operate flights from Houston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$318Average$565FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$738Average$894FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$824Average$1,001FlexibilityNo cancel feeOn-time70%

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