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$165+ Cheap flights from Houston to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — PTY
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Houston to Panama

Keep the following information in mind while searching for Houston to Panama flight deals. Data was last updated September 15, 2025.

Round-trip from

$412
(Kiwi.com)

One-way from

$165
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$906
From Houston to Panama
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One-way flight from Houston to Panama
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Highest demand for flights based on searches. 4% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Houston to Panama

Cheapest flights from Houston to Panama
Explore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2912:47 pmIAH - PTY
1 stop7h 32mMultiple Airlines
Thu 10/212:03 pmPTY - IAH
1 stop10h 39mMultiple Airlines
Deal found 9/13$412
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:55 amIAH - PTY
1 stop8h 25mMultiple Airlines
Sun 11/29:33 pmPTY - IAH
1 stop13h 27mMultiple Airlines
Deal found 9/13$415
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2010:55 amIAH - PTY
1 stop8h 34mMultiple Airlines
Thu 10/239:33 pmPTY - IAH
1 stop12h 27mMultiple Airlines
Deal found 9/14$419
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:55 amIAH - PTY
1 stop8h 34mMultiple Airlines
Sun 10/199:33 pmPTY - IAH
1 stop12h 27mMultiple Airlines
Deal found 9/15$420
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:45 amIAH - PTY
3 stops30h 50mMultiple Airlines
Mon 10/2010:05 pmPTY - IAH
3 stops23h 12mMultiple Airlines
Deal found 9/13$429
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:35 amIAH - PTY
1 stop10h 01mMultiple Airlines
Sun 11/99:33 pmPTY - IAH
1 stop13h 27mMultiple Airlines
Deal found 9/13$434
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:43 pmIAH - PTY
1 stop13h 28mMultiple Airlines
Sun 11/29:33 pmPTY - IAH
1 stop13h 27mMultiple Airlines
Deal found 9/13$435
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2710:54 amIAH - PTY
1 stop8h 35mMultiple Airlines
Thu 10/29:33 pmPTY - IAH
1 stop12h 21mMultiple Airlines
Deal found 9/13$437
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/258:00 pmIAH - PTY
1 stop12h 11mMultiple Airlines
Sat 11/89:43 pmPTY - IAH
1 stop11h 49mMultiple Airlines
Deal found 9/14$439
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1410:12 amIAH - PTY
2 stops13h 58mMultiple Airlines
Sun 10/127:55 amPTY - IAH
1 stop8h 30mMultiple Airlines
Deal found 9/12$442
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amHOU - PTY
1 stop6h 56mDelta
Tue 11/43:21 pmPTY - HOU
1 stop8h 39mDelta
Deal found 9/13$743
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:39 pmHOU - PTY
2 stops19h 24mAmerican Airlines
Fri 10/243:15 pmPTY - HOU
2 stops17h 13mAmerican Airlines
Deal found 9/14$758

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Houston to Panama that are best for you.

Fly from

Houston

Fly to

Panama

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Sun 10/12

6:43 pm-12:35 pm

3 stops17h 52m

Panama City Tocumen Intl

Thu 10/16

10:05 pm-12:28 am

3 stops26h 23m

$560

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Sat 10/11

6:35 am-7:29 pm

1 stop12h 54m

Panama City Tocumen Intl

Sat 10/18

12:48 pm-9:17 pm

1 stop8h 29m

$563

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 10/30

8:10 pm-7:25 pm

2 stops23h 15m

Panama City Tocumen Intl

Sun 11/2

2:55 pm-12:28 am

3 stops34h 33m

$578

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 2/11

9:47 am-10:20 am

1 stop23h 33m

Panama City Tocumen Intl

Wed 2/18

3:35 pm-4:57 pm

1 stop26h 22m

$624

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 10/14

2:05 pm-12:35 pm

2 stops22h 30m

Panama City Tocumen Intl

Thu 10/23

3:20 am-4:10 pm

2 stops12h 50m

$667

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 10/13

2:20 pm-6:37 pm

Nonstop4h 17m

Panama City Tocumen Intl

Mon 10/20

3:30 pm-7:50 pm

Nonstop4h 20m

$739

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 2/16

9:34 am-2:45 pm

Nonstop4h 11m

Panama City Tocumen Intl

Mon 2/23

8:55 am-12:14 pm

Nonstop4h 19m

$739

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 10/29

9:34 am-1:45 pm

Nonstop4h 11m

Panama City Tocumen Intl

Thu 11/13

4:41 pm-8:10 pm

Nonstop4h 29m

$739

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 3/4

11:56 am-5:07 pm

Nonstop4h 11m

Panama City Tocumen Intl

Wed 3/11

11:35 am-3:59 pm

Nonstop4h 24m

$739

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 10/28

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Tue 11/4

3:21 pm-11:00 pm

1 stop8h 39m

$743

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 52 results
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Best time to book a flight from Houston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Panama

What is the cheapest month to book a flight from Houston to Panama?

Currently, October is the cheapest month in which you can book a flight from Houston to Panama (average of $478). Flying from Houston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to PA?

Find hourly flight availability from Houston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Houston to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, United Airlines, and Avianca from Houston to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
United Airlines
7.4
Good
8,929 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Houston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Houston to Panama?

    There are many flights that can get you from Houston to Panama in 6h 56m. Fly via Avianca, Delta, or American Airlines to get the fastest option. There are 1753 mi between Houston and Panama. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Houston to Panama?

    Most travelers choose Houston Hobby - Panama City Tocumen Intl, Houston George Bush Intcntl - Panama City Tocumen Intl or Houston George Bush Intcntl - Bocas Del Toro when deciding on the best route from Houston to Panama.

  • Can I find deals for flights from Houston to Panama that include hotel bookings?

    Yes. In addition to deals on Houston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Panama.

  • Can I find deals for business class flights from Houston to Panama?

    Yes. Cheapflights offers flight deals from Houston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Panama?

    Currently, October is the cheapest month in which you can book a flight from Houston to Panama (average of $478). Flying from Houston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Houston to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to San Salvador flights
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George Bush Intcntl to San Salvador flights
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Top 3 airlines flying from Houston to Panama

Discover the top 3 airlines that operate flights from Houston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$318Average$565FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$738Average$895FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$824Average$1,078FlexibilityNo cancel feeOn-time70%

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