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$163+ Cheap flights from Houston to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Houston to Panama

Keep the following information in mind while searching for Houston to Panama flight deals. Data was last updated May 1, 2025.

Round-trip from

$402
(Mytrip)

One-way from

$163
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$853
From Houston to Panama
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One-way flight from Houston to Panama
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Houston to Panama

Cheapest flights from Houston to Panama
Explore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/225:35 amIAH - PTY
2 stops28h 35mMultiple Airlines
Mon 5/265:25 pmPTY - IAH
2 stops29h 21mMultiple Airlines
Deal found 4/29$402
This Trip.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/245:40 pmIAH - PTY
1 stop16h 45mAvianca
Sun 7/278:10 pmPTY - IAH
1 stop20h 00mAvianca
Deal found 4/29$594
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/36:00 amHOU - PTY
1 stop6h 48mDelta
Thu 6/122:23 pmPTY - HOU
1 stop8h 01mDelta
Deal found 4/29$753
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/32:28 pmHOU - PTY
2 stops21h 51mAmerican Airlines
Thu 6/121:50 pmPTY - HOU
2 stops19h 53mAmerican Airlines
Deal found 4/30$758

Cheapflights Fare Finder

Customize your flight search to find flights from Houston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Houston to Panama that are best for you.

Fly from

Houston

Fly to

Panama

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 5/22

5:35 am-10:10 am

2 stops28h 35m

Panama City Tocumen Intl

Mon 5/26

5:25 pm-10:46 pm

2 stops29h 21m

$402

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 7/24

5:40 pm-10:25 am

1 stop16h 45m

Panama City Tocumen Intl

Sun 7/27

8:10 pm-4:10 pm

1 stop20h 00m

$594

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 7/24

6:07 am-1:47 pm

1 stop7h 40m

Panama City Tocumen Intl

Mon 7/28

3:22 pm-12:11 pm

1 stop20h 49m

$703

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 6/3

6:00 am-12:48 pm

1 stop6h 48m

Panama City Tocumen Intl

Thu 6/12

2:23 pm-10:24 pm

1 stop8h 01m

$753

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 6/3

2:28 pm-12:19 pm

2 stops21h 51m

Panama City Tocumen Intl

Thu 6/12

1:50 pm-9:43 am

2 stops19h 53m

$758

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 6/3

4:24 pm-2:40 pm

2 stops22h 16m

$163

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 8/14

5:40 pm-10:10 am

3 stops16h 30m

$297

HoustonPanama City

IAH - PAC

IAHPAC

Houston George Bush Intcntl

Sun 8/10

5:30 am-7:20 pm

3 stops13h 50m

$391

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 6/3

9:59 am-2:14 pm

Nonstop4h 15m

$635

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 6/3

2:28 pm-12:19 pm

2 stops21h 51m

$639

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 11 results
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Best time to book a flight from Houston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Panama

What is the cheapest month to book a flight from Houston to Panama?

Currently, October is the cheapest month in which you can book a flight from Houston to Panama (average of $478). Flying from Houston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to PA?

Find hourly flight availability from Houston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Houston to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 1, 2025.
Get a feel of what it's like to fly with Delta, Aeromexico and United Airlines from Houston to Panama by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Aeromexico
7.5
Good
1,698 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Houston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Houston to Panama one-way?

    One-way options have recently been found by users for as low as $297 on Avianca. Other airlines that offer cheap prices include United Airlines from $635 and American Airlines from $639 one-way.

  • What are the most popular routes from Houston to Panama?

    Most travelers choose Houston Hobby - Panama City Tocumen Intl, Houston George Bush Intcntl - Panama City Tocumen Intl or Houston George Bush Intcntl - Bocas Del Toro when deciding on the best route from Houston to Panama.

  • Can I find deals for flights from Houston to Panama that include hotel bookings?

    Yes. In addition to deals on Houston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Panama.

  • Can I find deals for business class flights from Houston to Panama?

    Yes. Cheapflights offers flight deals from Houston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Panama?

    Currently, October is the cheapest month in which you can book a flight from Houston to Panama (average of $478). Flying from Houston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Houston to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Hobby to San Salvador flights
Dallas/Fort Worth to San Salvador flights
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Top 3 airlines flying from Houston to Panama

Discover the top 3 airlines that operate flights from Houston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$292Average$417FlexibilityNo cancel feeOn-time71%
American AirlinesCheapest$297Average$781FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$652Average$885FlexibilityNo cancel feeOn-time69%

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