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$183+ Cheap flights from Houston to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — PTY
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Houston to Panama

Keep the following information in mind while searching for Houston to Panama flight deals. Data was last updated July 31, 2025.

Round-trip from

$441
(Mytrip)

One-way from

$183
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$888
From Houston to Panama
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One-way flight from Houston to Panama
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($50 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Houston to Panama

Cheapest flights from Houston to Panama
Explore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/75:25 amIAH - PTY
2 stops15h 45mMultiple Airlines
Mon 9/83:25 amPTY - IAH
2 stops17h 42mMultiple Airlines
Deal found 7/31$441
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amHOU - PTY
1 stop6h 52mDelta
Sun 12/148:05 amPTY - HOU
1 stop9h 22mDelta
Deal found 7/31$778
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/148:32 pmHOU - PTY
2 stops17h 59mAmerican Airlines
Sun 9/213:31 pmPTY - HOU
2 stops17h 03mAmerican Airlines
Deal found 7/31$802

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Houston to Panama that are best for you.

Fly from

Houston

Fly to

Panama

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Sun 9/7

5:25 am-9:10 pm

2 stops15h 45m

Panama City Tocumen Intl

Mon 9/8

3:25 am-9:07 pm

2 stops17h 42m

$441

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Thu 12/4

6:00 am-1:52 pm

1 stop6h 52m

Panama City Tocumen Intl

Sun 12/14

8:05 am-4:27 pm

1 stop9h 22m

$778

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Sun 9/14

8:32 pm-2:31 pm

2 stops17h 59m

Panama City Tocumen Intl

Sun 9/21

3:31 pm-8:34 am

2 stops17h 03m

$802

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 9/9

2:27 pm-4:30 pm

2 stops26h 03m

$183

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 8/11

5:40 pm-10:25 am

1 stop16h 45m

$269

HoustonPanama City

IAH - PAC

IAHPAC

Houston George Bush Intcntl

Tue 9/9

5:34 am-7:20 pm

3 stops13h 46m

$357

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 9/23

4:26 pm-12:55 pm

2 stops20h 29m

$639

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Thu 8/14

6:00 am-12:50 pm

1 stop6h 50m

$719

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Best time to book a flight from Houston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Panama

What is the cheapest month to book a flight from Houston to Panama?

Currently, October is the cheapest month in which you can book a flight from Houston to Panama (average of $478). Flying from Houston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to PA?

Find hourly flight availability from Houston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Houston to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 31, 2025.
Peruse reviews from past customers who have flown with Delta, American Airlines, and Avianca from Houston to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,388 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Houston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Houston to Panama one-way?

    One-way options have recently been found by users for as low as $269 on Avianca. Other airlines that offer cheap prices include American Airlines from $639 and Delta from $719 one-way.

  • What are the most popular routes from Houston to Panama?

    Most travelers choose Houston Hobby - Panama City Tocumen Intl, Houston George Bush Intcntl - Panama City Tocumen Intl or Houston George Bush Intcntl - Bocas Del Toro when deciding on the best route from Houston to Panama.

  • Can I find deals for flights from Houston to Panama that include hotel bookings?

    Yes. In addition to deals on Houston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Panama.

  • Can I find deals for business class flights from Houston to Panama?

    Yes. Cheapflights offers flight deals from Houston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Panama?

    Currently, October is the cheapest month in which you can book a flight from Houston to Panama (average of $478). Flying from Houston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Houston to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Hobby to San Salvador flights
Dallas/Fort Worth to Panama City flights
Dallas/Fort Worth to San Salvador flights
George Bush Intcntl to San Salvador flights
Hobby to San José flights
George Bush Intcntl to San José flights
Dallas/Fort Worth to Guatemala City flights
Dallas/Fort Worth to San José flights
Hobby to Panama City flights
Hobby to Philip S.W.Goldson flights
Hobby to Guatemala City flights
Hobby to San Pedro Sula flights
George Bush Intcntl to Guatemala City flights
George Bush Intcntl to Philip S.W.Goldson flights
Dallas/Fort Worth to Philip S.W.Goldson flights
George Bush Intcntl to Panama City flights
George Bush Intcntl to San Pedro Sula flights
Dallas/Fort Worth to Liberia flights
Hobby to Liberia flights
Hobby to Managua flights
Austin to San José flights
George Bush Intcntl to Managua flights
Love Field to San Salvador flights
George Bush Intcntl to Liberia flights
Love Field to Guatemala City flights
Austin to Panama City flights
Austin to Liberia flights
Love Field to San José flights
Dallas/Fort Worth to Coxen Hole flights
Austin to Philip S.W.Goldson flights
San Antonio to San José flights
San Antonio to Panama City flights
Dallas/Fort Worth to San Pedro Sula flights
Love Field to Panama City flights
Dallas/Fort Worth to Managua flights
San Antonio to Guatemala City flights
Hobby to Coxen Hole flights
Austin to Guatemala City flights
Love Field to Philip S.W.Goldson flights
George Bush Intcntl to Coxen Hole flights
San Antonio to San Salvador flights
Love Field to Liberia flights
Austin to San Salvador flights
San Antonio to Philip S.W.Goldson flights
San Antonio to Liberia flights
Austin to Managua flights
San Antonio to Managua flights
Lubbock to Panama City flights
Austin to San Pedro Sula flights
El Paso to San José flights

Top 4 airlines flying from Houston to Panama

Discover the top 4 airlines that operate flights from Houston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$322Average$485FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$738Average$888FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$753Average$931FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$825Average$968FlexibilityNo cancel feeOn-time70%

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