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$161+ Cheap flights from Houston to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — PTY
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
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Cheap flight deals from Houston to Panama

Cheapest flights from Houston to Panama
Explore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:00 pm
IAH
-
PTY
2 stops30h 35m
Multiple Airlines
Sun 5/34:25 am
PTY
-
IAH
2 stops35h 51m
Multiple Airlines
Deal found 3/27$407
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:40 pm
IAH
-
PTY
1 stop11h 26m
Multiple Airlines
Wed 5/69:33 pm
PTY
-
IAH
1 stop10h 45m
Multiple Airlines
Deal found 3/30$408
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:39 am
IAH
-
PTY
2 stops26h 36m
Multiple Airlines
Thu 4/3010:10 am
PTY
-
IAH
2 stops31h 43m
Multiple Airlines
Deal found 3/31$411
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:00 pm
IAH
-
PTY
1 stop12h 06m
Multiple Airlines
Thu 5/79:33 pm
PTY
-
IAH
1 stop10h 45m
Multiple Airlines
Deal found 3/30$414
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:36 pm
IAH
-
PTY
1 stop10h 30m
Multiple Airlines
Wed 5/69:33 pm
PTY
-
IAH
1 stop10h 45m
Multiple Airlines
Deal found 3/27$415
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:36 pm
IAH
-
PTY
1 stop10h 30m
Multiple Airlines
Sat 5/26:34 pm
PTY
-
IAH
1 stop13h 49m
Multiple Airlines
Deal found 3/29$420
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 pm
IAH
-
PTY
1 stop14h 06m
Multiple Airlines
Wed 5/69:33 pm
PTY
-
IAH
1 stop10h 45m
Multiple Airlines
Deal found 3/30$421
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 pm
IAH
-
PTY
1 stop14h 06m
Multiple Airlines
Thu 4/2310:25 am
PTY
-
IAH
1 stop9h 30m
Multiple Airlines
Deal found 3/27$423
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 pm
IAH
-
PTY
1 stop14h 06m
Multiple Airlines
Thu 5/79:33 pm
PTY
-
IAH
1 stop10h 45m
Multiple Airlines
Deal found 3/30$425
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 pm
IAH
-
PTY
1 stop14h 30m
Multiple Airlines
Sat 5/29:33 pm
PTY
-
IAH
1 stop10h 50m
Multiple Airlines
Deal found 3/29$427
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 pm
IAH
-
PTY
1 stop14h 06m
Multiple Airlines
Sat 5/29:33 pm
PTY
-
IAH
1 stop10h 50m
Multiple Airlines
Deal found 3/30$428
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:02 pm
HOU
-
PTY
1 stop19h 48m
Delta
Mon 6/82:24 pm
PTY
-
HOU
1 stop18h 50m
Delta
Deal found 3/29$834

Find flight deals from Houston to Panama

Keep the following information in mind while searching for Houston to Panama flight deals. Data was last updated April 1, 2026.

Round-trip from

$407
(Mytrip)

One-way from

$161
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$1,163
From Houston to Panama
Search Deals
One-way flight from Houston to Panama
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($57 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Houston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Houston to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 5/26

2:24 pm-6:37 pm

Nonstop4h 13m

Panama City Tocumen Intl

Tue 6/2

7:55 am-12:19 pm

Nonstop4h 24m

$830

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 4/29

2:24 pm-6:37 pm

Nonstop4h 13m

Panama City Tocumen Intl

Wed 5/6

10:00 am-2:24 pm

Nonstop4h 24m

$830

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Wed 5/20

5:02 pm-12:50 pm

1 stop19h 48m

Panama City Tocumen Intl

Mon 6/8

2:24 pm-9:14 am

1 stop18h 50m

$834

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Sun 5/17

5:02 pm-12:50 pm

1 stop19h 48m

Panama City Tocumen Intl

Wed 6/10

2:24 pm-9:14 am

1 stop18h 50m

$834

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 4/28

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Tue 5/5

2:27 pm-11:07 pm

1 stop8h 40m

$845

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 5/5

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Tue 5/12

2:15 pm-10:26 pm

1 stop8h 11m

$845

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Wed 5/6

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Wed 6/3

2:15 pm-10:26 pm

1 stop8h 11m

$845

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Wed 4/29

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Wed 5/6

2:27 pm-11:07 pm

1 stop8h 40m

$845

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Wed 5/13

4:19 pm-12:46 pm

2 stops20h 27m

Panama City Tocumen Intl

Fri 5/22

1:14 pm-8:57 am

2 stops19h 43m

$849

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 5/21

11:59 am-4:12 pm

Nonstop4h 13m

Panama City Tocumen Intl

Fri 6/12

10:00 am-2:24 pm

Nonstop4h 24m

$855

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/29

Showing 1-10 of 51 resultsSorted by cheapest first
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Best time to book a flight from Houston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Panama

What is the cheapest month to book a flight from Houston to Panama?

Currently, May is the cheapest month in which you can book a flight from Houston to Panama (average of $553). Flying from Houston to Panama in October is currently the most expensive (average of $778). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to PA?

Find hourly flight availability from Houston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2026.

When flying from Houston to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How often are flights from Houston to Panama delayed?

About 16% of weekly flights between Houston and Panama have experienced delays in the past year, with the average delay time being 141 minutes.

What is the most punctual flight time for Houston to Panama flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Tuesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Houston to Panama flights?

Over the last year, United Airlines have had the lowest number of delays on this route, with just 16% of flights being delayed.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 1, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Houston to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,578 reviews

Boarding

7.8

Comfort

7.4

Overall

7.5

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,578 reviews
Copa Airlines
7.5
Good
1,578 reviews

Boarding

7.8

Comfort

7.4

Overall

7.5

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
United Airlines
7.4
Good
9,530 reviews
Copa Airlines
7.5
Good
1,578 reviews

Boarding

7.8

Comfort

7.4

Overall

7.5

Entertainment

6.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Houston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Houston to Panama?

    There are many flights that can get you from Houston to Panama in 4h 15m. Fly via United Airlines, Delta, or Avianca to get the fastest option. There are 1774 mi between Houston and Panama. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Houston to Panama?

    Most travelers choose Houston Hobby - Panama City Tocumen Intl, Houston George Bush Intcntl - Panama City Tocumen Intl or Houston George Bush Intcntl - Panama City Marcos A. Gelabert Intl when deciding on the best route from Houston to Panama.

  • Can I find deals for flights from Houston to Panama that include hotel bookings?

    Yes. In addition to deals on Houston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Panama.

  • Can I find deals for business class flights from Houston to Panama?

    Yes. Cheapflights offers flight deals from Houston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Panama?

    Currently, May is the cheapest month in which you can book a flight from Houston to Panama (average of $553). Flying from Houston to Panama in October is currently the most expensive (average of $778). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Houston to Panama

Discover the top 2 airlines that operate flights from Houston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$559Average$860FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$738Average$904FlexibilityNo cancel feeOn-time69%

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