$175+ Cheap flights from Houston to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Panama
Cheapest flights from Houston to PanamaExplore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
Explore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from Houston to Panama
Keep the following information in mind while searching for Houston to Panama flight deals. Data was last updated December 18, 2025.
Round-trip from | $449 (Avianca Connect) |
|---|---|
One-way from | $175 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $1,001 |
Cheapflights Fare Finder
Use the filters below to find and compare flights from Houston to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Fri 1/23
7:30 am-6:55 pm
1 stop10h 25m
Panama City Tocumen Intl
Fri 1/30
7:50 pm-2:37 pm
1 stop19h 47m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 1/26
7:30 am-6:55 pm
1 stop10h 25m
Panama City Tocumen Intl
Tue 1/27
3:50 pm-2:37 pm
1 stop23h 47m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sat 1/24
4:20 pm-2:00 pm
2 stops20h 40m
Panama City Tocumen Intl
Sat 1/31
2:55 am-8:23 pm
2 stops18h 28m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Thu 2/26
10:08 am-7:20 pm
1 stop8h 12m
Panama City Tocumen Intl
Mon 3/2
3:39 pm-11:59 pm
1 stop9h 20m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Wed 2/4
8:30 am-8:06 am
1 stop22h 36m
Panama City Tocumen Intl
Sat 2/28
9:45 am-11:59 pm
2 stops15h 14m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Tue 3/17
5:23 pm-8:30 am
1 stop15h 07m
Panama City Tocumen Intl
Tue 3/24
3:39 pm-11:49 pm
1 stop8h 10m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sun 1/25
4:20 pm-12:40 am
2 stops31h 20m
Panama City Tocumen Intl
Tue 3/10
2:55 am-2:17 pm
3 stops35h 22m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Fri 2/6
4:20 pm-8:50 am
2 stops15h 30m
Panama City Tocumen Intl
Sun 2/15
10:26 am-10:51 pm
1 stop13h 25m
HoustonPanama City
HOU - PTY
HOUPTY
Houston Hobby
Wed 3/18
6:00 am-12:55 pm
1 stop6h 55m
Panama City Tocumen Intl
Wed 3/25
2:20 pm-10:28 pm
1 stop8h 08m
HoustonPanama City
HOU - PTY
HOUPTY
Houston Hobby
Tue 3/17
5:27 pm-12:55 pm
1 stop19h 28m
Panama City Tocumen Intl
Tue 3/24
2:20 pm-9:40 am
1 stop19h 20m
Best time to book a flight from Houston to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Houston with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Houston to Panama
What is the cheapest month to book a flight from Houston to Panama?
Currently, January is the cheapest month in which you can book a flight from Houston to Panama (average of $416). Flying from Houston to Panama in December is currently the most expensive (average of $778). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from HOU to PA?
Find hourly flight availability from Houston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.
One of the essential ways to save on airfare from Houston to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 72% on airfare.
How often are flights from Houston to Panama delayed?
About 19% of weekly flights between Houston and Panama have experienced delays in the past year, with the average delay time being 146 minutes.
What is the most punctual flight time for Houston to Panama flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Friday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Houston to Panama flights?
Over the last year, United Airlines have had the lowest number of delays on this route, with just 19% of flights being delayed.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 18, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Houston to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
Crew
Comfort
Entertainment
Food
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Overall
Crew
Comfort
Entertainment
Food
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Overall
Crew
Comfort
Entertainment
Food
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Related info for your journey
Find useful and relevant information for your journey from Houston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Houston to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Houston to Panama
Discover the top 2 airlines that operate flights from Houston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$738 | Average$890 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$846 | Average$888 | FlexibilityNo cancel fee | On-time70% |