$160+ Cheap flights from Houston to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Houston to Panama
Cheapest flights from Houston to PanamaExplore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
Explore the most affordable flight options available from Houston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from Houston to Panama
Keep the following information in mind while searching for Houston to Panama flight deals. Data was last updated January 29, 2026.
Round-trip from | $433 (Mytrip) |
|---|---|
One-way from | $160 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $788 |
Cheapflights Fare Finder
Use the filters below to find and compare flights from Houston to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Tue 2/24
6:30 am-2:00 pm
3 stops30h 30m
Panama City Tocumen Intl
Tue 3/3
5:50 pm-12:18 am
3 stops31h 28m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Wed 3/11
6:30 am-4:55 pm
2 stops34h 25m
Panama City Tocumen Intl
Mon 3/16
2:55 pm-11:59 pm
3 stops33h 04m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 3/2
9:40 pm-1:00 am
3 stops26h 20m
Panama City Tocumen Intl
Sat 5/2
3:05 am-11:51 pm
2 stops20h 46m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Tue 3/24
5:24 pm-8:50 am
2 stops15h 26m
Panama City Tocumen Intl
Mon 4/6
5:30 am-4:10 pm
1 stop10h 40m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sun 3/22
5:45 am-2:55 pm
2 stops9h 10m
Panama City Tocumen Intl
Sat 4/4
5:30 am-12:05 pm
1 stop6h 35m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sun 3/22
5:24 pm-8:06 am
1 stop14h 42m
Panama City Tocumen Intl
Mon 4/6
10:25 am-11:49 pm
1 stop13h 24m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 4/20
11:37 am-8:37 pm
1 stop9h 00m
Panama City Tocumen Intl
Mon 4/27
3:41 pm-11:51 pm
1 stop8h 10m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sat 3/14
5:24 pm-8:50 am
2 stops15h 26m
Panama City Tocumen Intl
Tue 3/17
10:25 am-11:49 pm
1 stop13h 24m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Mon 6/8
5:45 pm-1:55 am
1 stop8h 10m
Panama City Tocumen Intl
Fri 6/12
5:55 pm-12:05 pm
2 stops18h 10m
HoustonPanama City
IAH - PTY
IAHPTY
Houston George Bush Intcntl
Sun 2/15
1:00 pm-8:50 am
2 stops18h 50m
Panama City Tocumen Intl
Mon 3/2
5:50 pm-11:05 am
2 stops18h 15m
Best time to book a flight from Houston to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Houston with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Houston to Panama
What is the cheapest month to book a flight from Houston to Panama?
Currently, March is the cheapest month in which you can book a flight from Houston to Panama (average of $559). Flying from Houston to Panama in December is currently the most expensive (average of $778). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from HOU to PA?
Find hourly flight availability from Houston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.
When flying from Houston to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from Houston to Panama delayed?
About 18% of weekly flights between Houston and Panama have experienced delays in the past year, with the average delay time being 151 minutes.
What is the most punctual flight time for Houston to Panama flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Houston to Panama flights?
Over the last year, United Airlines have had the lowest number of delays on this route, with just 18% of flights being delayed.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Houston to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
Entertainment
Food
Boarding
Crew
Overall
Reviews
Juan,Dec 2025
EZE - PTY
Comfort
Entertainment
Food
Boarding
Crew
Overall
Reviews
Juan,Dec 2025
EZE - PTY
Comfort
Entertainment
Food
Boarding
Crew
Overall
Reviews
Juan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from Houston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Houston to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Houston to Panama
Discover the top 2 airlines that operate flights from Houston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$555 | Average$764 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$738 | Average$898 | FlexibilityNo cancel fee | On-time69% |