$65+ Cheap flights from Orlando (MCO) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
MCO — STL
May 15 — May 221
Round-trip
1 adult, Economy
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Cheapest flights from Orlando to MissouriExplore the most affordable flight options available from Orlando to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2026.
Explore the most affordable flight options available from Orlando to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2026.
This CheapOair deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:18 pm
MCO
- STL
Nonstop2h 39m
Frontier
Sun 6/78:08 pm
STL
- MCO
1 stop14h 35m
Frontier
Deal found 4/13![Frontier logo]()
$150
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:18 pm
MCO
- STL
Nonstop2h 39m
Frontier
Thu 5/284:19 pm
STL
- MCO
Nonstop2h 34m
Frontier
Deal found 4/14![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:44 pm
MCO
- STL
1 stop11h 11m
Multiple Airlines
Sun 5/104:19 pm
STL
- MCO
Nonstop2h 34m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:56 am
MCO
- STL
1 stop7h 19m
Frontier
Mon 5/255:27 pm
STL
- MCO
1 stop12h 13m
Frontier
Deal found 4/10![Frontier logo]()
$153
This eDestinos deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:42 pm
MCO
- STL
Nonstop2h 39m
Frontier
Sun 5/174:19 pm
STL
- MCO
Nonstop2h 34m
Frontier
Deal found 4/11![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:44 pm
MCO
- STL
1 stop11h 11m
Multiple Airlines
Tue 5/266:33 pm
STL
- MCO
1 stop11h 07m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:56 am
MCO
- STL
1 stop8h 37m
Multiple Airlines
Tue 5/196:33 pm
STL
- MCO
1 stop13h 57m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:52 pm
MCO
- STL
1 stop9h 58m
Multiple Airlines
Wed 5/205:27 pm
STL
- MCO
1 stop12h 13m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:10 pm
MCO
- STL
1 stop18h 45m
Multiple Airlines
Mon 5/115:27 pm
STL
- MCO
2 stops14h 51m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$158
This Cheapflightsfares deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:56 am
MCO
- STL
1 stop9h 58m
Frontier
Sun 5/173:33 pm
STL
- MCO
1 stop8h 56m
Frontier
Deal found 4/10![Frontier logo]()
$159
This Frontier deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:49 pm
MCO
- STL
1 stop10h 01m
Frontier
Sun 5/311:28 am
STL
- MCO
1 stop7h 53m
Frontier
Deal found 4/10![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:15 am
MCO
- STL
1 stop6h 16m
Frontier
Wed 4/224:59 pm
STL
- MCO
Nonstop2h 26m
Frontier
Deal found 4/10![Frontier logo]()
$161
Best flights from Orlando to MissouriDiscover carefully curated flight deals from Orlando to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 15, 2026.
Discover carefully curated flight deals from Orlando to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 15, 2026.
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:20 pm
MCO
- STL
Nonstop2h 35m
Southwest
Wed 5/203:55 pm
STL
- MCO
Nonstop2h 25m
Southwest
Deal found 4/10![Southwest logo]()
$274
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:00 pm
MCO
- MCI
1 stop6h 31m
Delta
Sun 5/107:05 am
MCI
- MCO
1 stop7h 08m
Delta
Deal found 4/10![Delta logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:40 pm
MCO
- UIN
2 stops26h 25m
Multiple Airlines
Thu 4/305:25 pm
UIN
- MCO
1 stop15h 59m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:15 am
MCO
- COU
1 stop8h 17m
United Airlines
Tue 5/1911:30 am
COU
- MCO
1 stop6h 00m
United Airlines
Deal found 4/11![United Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:49 pm
MCO
- COU
1 stop7h 04m
American Airlines
Sat 5/210:16 am
COU
- MCO
1 stop5h 31m
American Airlines
Deal found 4/13![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:25 pm
MCO
- COU
1 stop8h 34m
United Airlines
Sat 7/43:05 pm
COU
- MCO
1 stop5h 50m
United Airlines
Deal found 4/14![United Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:30 am
MCO
- MCI
1 stop5h 38m
Delta
Tue 6/912:20 pm
MCI
- MCO
1 stop7h 15m
Delta
Deal found 4/12![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:35 am
MCO
- STL
Nonstop2h 40m
Southwest
Mon 5/187:40 pm
STL
- MCO
Nonstop2h 20m
Southwest
Deal found 4/12![Southwest logo]()
$355
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:12 pm
MCO
- COU
2 stops10h 51m
United Airlines
Tue 5/123:10 pm
COU
- MCO
1 stop5h 45m
United Airlines
Deal found 4/13![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:54 pm
MCO
- MCI
1 stop9h 34m
Delta
Wed 6/177:00 am
MCI
- MCO
1 stop7h 35m
Delta
Deal found 4/12![Delta logo]()
$357
This Orbitz deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:51 am
MCO
- MCI
1 stop10h 30m
Multiple Airlines
Sun 6/219:50 am
MCI
- MCO
Nonstop2h 46m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:40 am
MCO
- COU
2 stops8h 52m
United Airlines
Sat 5/163:10 pm
COU
- MCO
2 stops8h 49m
United Airlines
Deal found 4/11![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:15 am
MCO
- MCI
Nonstop3h 10m
Southwest
Mon 5/118:55 pm
MCI
- MCO
Nonstop2h 45m
Southwest
Deal found 4/14![Southwest logo]()
$373
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:09 am
MCO
- COU
1 stop10h 49m
American Airlines
Tue 5/1910:16 am
COU
- MCO
2 stops10h 00m
American Airlines
Deal found 4/12![American Airlines logo]()
$427
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/103:05 pm
MCO
- COU
2 stops9h 01m
United Airlines
Wed 6/245:00 am
COU
- MCO
2 stops8h 47m
United Airlines
Deal found 4/13![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:05 pm
MCO
- STL
Nonstop2h 35m
Southwest
Mon 7/65:40 pm
STL
- MCO
1 stop5h 25m
Southwest
Deal found 4/12![Southwest logo]()
$404
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:30 am
MCO
- MCI
1 stop4h 59m
Delta
Sun 8/25:34 pm
MCI
- MCO
1 stop5h 24m
Delta
Deal found 4/13![Delta logo]()
$405
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:10 am
MCO
- COU
2 stops11h 51m
United Airlines
Wed 5/611:30 am
COU
- MCO
1 stop6h 00m
United Airlines
Deal found 4/15![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:30 am
MCO
- MCI
1 stop6h 45m
Delta
Sun 7/53:48 pm
MCI
- MCO
1 stop7h 04m
Delta
Deal found 4/14![Delta logo]()
$417
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:30 am
MCO
- MCI
Nonstop2h 55m
Southwest
Tue 7/75:10 pm
MCI
- MCO
Nonstop2h 50m
Southwest
Deal found 4/13![Southwest logo]()
$432
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:39 pm
MCO
- COU
1 stop6h 07m
American Airlines
Mon 6/2211:44 am
COU
- MCO
1 stop8h 27m
American Airlines
Deal found 4/10![American Airlines logo]()
$528
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:50 am
MCO
- STL
Nonstop2h 40m
Southwest
Sat 5/235:05 pm
STL
- MCO
Nonstop2h 25m
Southwest
Deal found 4/11![Southwest logo]()
$440
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:15 pm
MCO
- SGF
1 stop6h 04m
Delta
Mon 5/186:52 pm
SGF
- MCO
1 stop5h 03m
Delta
Deal found 4/11![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:13 am
MCO
- JLN
1 stop7h 09m
United Airlines
Mon 6/151:57 pm
JLN
- MCO
1 stop8h 44m
United Airlines
Deal found 4/13![United Airlines logo]()
$413
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:30 pm
MCO
- STL
2 stops5h 45m
Southwest
Thu 4/301:35 pm
STL
- MCO
1 stop5h 25m
Southwest
Deal found 4/13![Southwest logo]()
$440
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:02 pm
MCO
- STL
1 stop7h 33m
United Airlines
Wed 6/241:13 pm
STL
- MCO
2 stops10h 48m
United Airlines
Deal found 4/11![United Airlines logo]()
$416
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:55 pm
MCO
- MCI
Nonstop3h 05m
Southwest
Tue 5/196:45 pm
MCI
- MCO
Nonstop2h 40m
Southwest
Deal found 4/13![Southwest logo]()
$462
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:15 pm
MCO
- STL
1 stop5h 58m
United Airlines
Sat 5/910:25 am
STL
- MCO
2 stops10h 34m
United Airlines
Deal found 4/11![United Airlines logo]()
$436
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:07 am
MCO
- STL
2 stops11h 06m
United Airlines
Fri 5/157:45 am
STL
- MCO
1 stop8h 03m
United Airlines
Deal found 4/10![United Airlines logo]()
$436
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:15 am
MCO
- JLN
1 stop7h 22m
United Airlines
Mon 5/189:06 am
JLN
- MCO
2 stops10h 16m
United Airlines
Deal found 4/13![United Airlines logo]()
$440
Last-minute flights from Orlando to MissouriDiscover last-minute flight deals from Orlando to Missouri. Data last updated April 15, 2026 and is based on user searches.
Discover last-minute flight deals from Orlando to Missouri. Data last updated April 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:15 am
MCO
- STL
1 stop6h 16m
Frontier
Wed 4/224:59 pm
STL
- MCO
Nonstop2h 26m
Frontier
Deal found 4/10![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:34 pm
MCO
- STL
1 stop10h 16m
Frontier
Wed 5/205:27 pm
STL
- MCO
1 stop12h 13m
Frontier
Deal found 4/11![Frontier logo]()
$162
This Frontier deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:49 pm
MCO
- STL
1 stop10h 01m
Frontier
Sun 5/311:28 am
STL
- MCO
1 stop7h 53m
Frontier
Deal found 4/10![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:52 pm
MCO
- STL
1 stop9h 58m
Multiple Airlines
Wed 5/205:27 pm
STL
- MCO
1 stop12h 13m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:44 pm
MCO
- STL
1 stop11h 11m
Multiple Airlines
Sun 5/104:19 pm
STL
- MCO
Nonstop2h 34m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:10 pm
MCO
- STL
1 stop18h 45m
Multiple Airlines
Mon 5/115:27 pm
STL
- MCO
2 stops14h 51m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:56 am
MCO
- STL
1 stop8h 37m
Multiple Airlines
Tue 5/196:33 pm
STL
- MCO
1 stop13h 57m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$156
This Cheapflightsfares deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:56 am
MCO
- STL
1 stop9h 58m
Frontier
Sun 5/173:33 pm
STL
- MCO
1 stop8h 56m
Frontier
Deal found 4/10![Frontier logo]()
$159
This eDestinos deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:42 pm
MCO
- STL
Nonstop2h 39m
Frontier
Sun 5/174:19 pm
STL
- MCO
Nonstop2h 34m
Frontier
Deal found 4/11![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:56 am
MCO
- STL
1 stop7h 19m
Frontier
Mon 5/255:27 pm
STL
- MCO
1 stop12h 13m
Frontier
Deal found 4/10![Frontier logo]()
$153
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:18 pm
MCO
- STL
Nonstop2h 39m
Frontier
Thu 5/284:19 pm
STL
- MCO
Nonstop2h 34m
Frontier
Deal found 4/14![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:44 pm
MCO
- STL
1 stop11h 11m
Multiple Airlines
Tue 5/266:33 pm
STL
- MCO
1 stop11h 07m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$155
One-way flights from Orlando to MissouriSearch for one-way flight options from Orlando to Missouri. Find affordable one-way fares based on user searches. Data last updated April 15, 2026.
Search for one-way flight options from Orlando to Missouri. Find affordable one-way fares based on user searches. Data last updated April 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:51 am
MCO
- MCI
1 stop10h 30m
Frontier
Deal found 4/14![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:44 pm
MCO
- MCI
1 stop20h 37m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$68
This Cheapflightsfares deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:30 am
MCO
- MCI
Nonstop2h 59m
Spirit Airlines
Deal found 4/15![Spirit Airlines logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:30 am
MCO
- MCI
Nonstop2h 59m
Spirit Airlines
Deal found 4/15![Spirit Airlines logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/149:18 pm
MCO
- MCI
1 stop21h 06m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$82
This eDestinos deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:48 pm
MCO
- STL
1 stop7h 35m
Frontier
Deal found 4/10![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:44 pm
MCO
- MCI
1 stop19h 37m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$83
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:18 pm
MCO
- STL
Nonstop2h 39m
Frontier
Deal found 4/14![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:10 pm
MCO
- STL
1 stop16h 45m
Frontier
Deal found 4/11![Frontier logo]()
$85
This Super.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:30 am
MCO
- MCI
Nonstop2h 59m
Spirit Airlines
Deal found 4/12![Spirit Airlines logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:41 pm
MCO
- STL
2 stops15h 14m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$86
This Frontier deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:56 am
MCO
- MCI
1 stop10h 33m
Frontier
Deal found 4/12![Frontier logo]()
$86
Find flight deals from Orlando to Missouri
Keep the following information in mind while searching for Orlando to Missouri flight deals. Data was last updated April 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $150 (CheapOair) |
One-way from | $65 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $216 |
Good round-trip deal | $234 or less |
Good one-way deal | $183 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Orlando to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
Use the filters below to find and compare flights from Orlando Airport to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
OrlandoSt. Louis
MCO - STL
MCOSTL
Orlando
Mon 5/18
7:20 pm-8:55 pm
Nonstop2h 35m
Lambert-St Louis
Wed 5/20
3:55 pm-7:20 pm
Nonstop2h 25m
$274
OrlandoKansas City
MCO - MCI
MCOMCI
Orlando
Fri 5/8
12:00 pm-5:31 pm
1 stop6h 31m
Kansas City
Sun 5/10
7:05 am-3:13 pm
1 stop7h 08m
$277
OrlandoQuincy
MCO - UIN
MCOUIN
Orlando
Tue 4/28
2:40 pm-4:05 pm
2 stops26h 25m
Quincy Regional
Thu 4/30
5:25 pm-10:24 am
1 stop15h 59m
$326
OrlandoColumbia
MCO - COU
MCOCOU
Orlando
Tue 5/12
7:15 am-2:32 pm
1 stop8h 17m
Columbia Regional
Tue 5/19
11:30 am-6:30 pm
1 stop6h 00m
$328
OrlandoColumbia
MCO - COU
MCOCOU
Orlando
Wed 7/1
2:25 pm-9:59 pm
1 stop8h 34m
Columbia Regional
Sat 7/4
3:05 pm-9:55 pm
1 stop5h 50m
$328
OrlandoColumbia
MCO - COU
MCOCOU
Orlando
Tue 5/5
12:12 pm-10:03 pm
2 stops10h 51m
Columbia Regional
Tue 5/12
3:10 pm-9:55 pm
1 stop5h 45m
$334
OrlandoKansas City
MCO - MCI
MCOMCI
Orlando
Wed 5/27
11:30 am-4:08 pm
1 stop5h 38m
Kansas City
Tue 6/9
12:20 pm-8:35 pm
1 stop7h 15m
$337
OrlandoColumbia
MCO - COU
MCOCOU
Orlando
Sat 5/9
6:40 am-2:32 pm
2 stops8h 52m
Columbia Regional
Sat 5/16
3:10 pm-12:59 am
2 stops8h 49m
$339
OrlandoColumbia
MCO - COU
MCOCOU
Orlando
Wed 6/10
3:05 pm-11:06 pm
2 stops9h 01m
Columbia Regional
Wed 6/24
5:00 am-2:47 pm
2 stops8h 47m
$339
OrlandoColumbia
MCO - COU
MCOCOU
Orlando
Wed 4/29
11:10 am-10:01 pm
2 stops11h 51m
Columbia Regional
Wed 5/6
11:30 am-6:30 pm
1 stop6h 00m
$349
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Orlando to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Orlando with our price prediction graph.
MCO-MCI
MCO-STL
MCO-UIN
MCO-COU
MCO-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Orlando Airport to Missouri
MCO-USMO
MCO-MCI
MCO-STL
MCO-UIN
MCO-COU
What is the cheapest month to book a flight from Orlando Airport to Missouri?
Currently, December is the cheapest month in which you can book a flight from Orlando Airport to Missouri (average of $40). Flying from Orlando Airport to Missouri in June is currently the most expensive (average of $149). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MCO to MO?
Find hourly flight availability from Orlando to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2026.
A simple way to save on the total cost of your ticket is to fly from Orlando Airport to Missouri in the evening. If you’re flexible enough to do this you can expect to save up to 37% on your trip compared to booking a flight at noon.
What is the cheapest day to fly from Orlando Airport to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Orlando to Missouri. Price data was last updated on April 11, 2026.
Travelers seeking maximum savings on their Orlando Airport to Missouri flight should consider departing on Sunday afternoons when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Orlando Airport to Missouri
Explore weekly flight availability from Orlando to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 15, 2026.
The most flights from MCO to USMO are scheduled on a Monday (11 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Orlando Airport to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 15, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Orlando Airport to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Orlando to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Orlando to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Orlando to Missouri by cabin class
Find flights from Orlando to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Orlando and Missouri flights
Browse other Orlando and Missouri flight options. Last updated on April 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Orlando to Missouri flights
Consider these flights traveling from Orlando to Missouri.
Top 6 airlines flying from Orlando to Missouri
Discover the top 6 airlines that operate flights from Orlando to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$53 | Average$171 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$100 | Average$168 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$195 | Average$410 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$198 | Average$380 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$255 | Average$400 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$458 | FlexibilityNo cancel fee | On-time69% |