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Mesa

$80+ Cheap flights from Myrtle Beach (MYR) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — PHX
Apr 24 — May 11
Fri 4/24
Fri 5/1
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Mesa

Cheapest flights from Myrtle Beach to Mesa
Explore the most affordable flight options available from Myrtle Beach to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.

This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
MYR
-
PHX
1 stop9h 12m
Delta
Tue 5/1910:55 pm
PHX
-
MYR
1 stop8h 42m
Delta
Deal found 3/24$261
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:15 am
MYR
-
PHX
2 stops9h 10m
Southwest
Tue 4/285:55 am
PHX
-
MYR
1 stop6h 30m
Southwest
Deal found 3/23$266
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:52 pm
MYR
-
PHX
1 stop7h 51m
American Airlines
Mon 4/2010:17 pm
PHX
-
MYR
1 stop8h 28m
American Airlines
Deal found 3/24$288
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:52 am
MYR
-
PHX
2 stops26h 18m
Multiple Airlines
Fri 4/243:51 pm
PHX
-
MYR
1 stop24h 47m
Multiple Airlines
Deal found 3/20$294
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
MYR
-
PHX
1 stop8h 05m
Delta
Fri 5/2910:55 pm
PHX
-
MYR
1 stop8h 42m
Delta
Deal found 3/24$314
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:21 pm
MYR
-
PHX
1 stop7h 49m
Delta
Mon 5/1812:15 pm
PHX
-
MYR
1 stop8h 43m
Delta
Deal found 3/24$315
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/102:55 pm
MYR
-
PHX
1 stop27h 06m
Multiple Airlines
Wed 5/136:53 pm
PHX
-
MYR
2 stops13h 55m
Multiple Airlines
Deal found 3/21$320
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:28 pm
MYR
-
PHX
2 stops21h 41m
Multiple Airlines
Fri 5/153:51 pm
PHX
-
MYR
1 stop16h 55m
Multiple Airlines
Deal found 3/21$323
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:08 pm
MYR
-
PHX
2 stops10h 51m
United Airlines
Mon 6/16:54 pm
PHX
-
MYR
2 stops12h 05m
United Airlines
Deal found 3/23$324
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:14 pm
MYR
-
PHX
2 stops31h 07m
Multiple Airlines
Fri 5/153:51 pm
PHX
-
MYR
1 stop16h 55m
Multiple Airlines
Deal found 3/21$325
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/72:55 pm
MYR
-
PHX
1 stop27h 06m
Multiple Airlines
Sun 5/1011:30 pm
PHX
-
MYR
2 stops18h 28m
Multiple Airlines
Deal found 3/19$331

Find flight deals from Myrtle Beach to Mesa

Keep the following information in mind while searching for Myrtle Beach to Mesa flight deals. Data was last updated March 25, 2026.

Round-trip from

$261
(Delta)

One-way from

$80
(Frontier)

Popular in

October

Cheapest in

April

Average price

$433
From Myrtle Beach Intl to Mesa
Search Deals
One-way flight from Myrtle Beach Intl to Mesa
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Wed 5/27

6:00 am-11:05 am

1 stop8h 05m

Phoenix Sky Harbor Intl

Wed 5/27

10:55 pm-10:37 am

1 stop8h 42m

$332

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Sat 5/23

6:00 am-11:05 am

1 stop8h 05m

Phoenix Sky Harbor Intl

Sun 5/31

12:15 pm-11:58 pm

1 stop8h 43m

$391
Quickest round-trip

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Fri 5/8

7:20 pm-11:50 pm

1 stop7h 30m

Phoenix Sky Harbor Intl

Tue 5/19

6:00 am-5:35 pm

1 stop8h 35m

$414

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Sat 5/23

5:05 pm-10:30 pm

1 stop8h 25m

Phoenix Sky Harbor Intl

Sun 5/31

6:05 pm-10:05 am

1 stop13h 00m

$440

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Fri 4/24

3:15 pm-10:20 pm

1 stop10h 05m

Phoenix Sky Harbor Intl

Mon 4/27

7:08 pm-10:18 am

2 stops12h 10m

$446

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Thu 5/7

3:45 pm-10:40 pm

2 stops9h 55m

Phoenix Sky Harbor Intl

Sun 5/10

6:45 am-7:20 pm

2 stops9h 35m

$455

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Mon 5/18

10:55 am-4:40 pm

2 stops8h 45m

Phoenix Sky Harbor Intl

Tue 5/26

7:05 am-8:30 pm

2 stops10h 25m

$513

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Fri 5/8

3:14 pm-10:01 pm

1 stop9h 47m

Phoenix Sky Harbor Intl

Sat 5/9

11:30 pm-10:42 am

1 stop8h 12m

$535

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Thu 5/7

11:30 am-9:32 pm

2 stops13h 02m

Phoenix Sky Harbor Intl

Mon 5/11

6:44 pm-11:04 am

2 stops13h 20m

$541

Myrtle BeachPhoenix

MYR - PHX

MYRPHX

Myrtle Beach Intl

Wed 5/20

3:14 pm-11:53 pm

1 stop11h 39m

Phoenix Sky Harbor Intl

Fri 5/29

6:59 pm-9:59 am

2 stops12h 00m

$563

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Myrtle Beach to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Mesa

How far ahead should I book a flight from Myrtle Beach to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Mesa. Price data was last updated on March 13, 2026.

Booking 15 days in advance of your planned departure date is, on average, the best time to get cheap flights from Myrtle Beach to Mesa. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Myrtle Beach to Mesa?

Currently, April is the cheapest month in which you can book a flight from Myrtle Beach to Mesa (average of $198). Flying from Myrtle Beach to Mesa in November is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated March 25, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Myrtle Beach to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,332 reviews
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,327 reviews
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,494 reviews
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Mesa?

    Located just 2.1 mi from the city center, Myrtle Beach Intl is the airport most travelers will use when flying to Mesa from Myrtle Beach. Booking flights from Myrtle Beach Intl (MYR) to Mesa should be relatively easy as there are 0 daily outbound flights to Mesa from 3 different airlines.

  • How long is the flight from Myrtle Beach to Mesa?

    A quick flight from Myrtle Beach to Mesa can take about 7h 30m. Delta provides one of the quickest options available for as low as $414. Airlines will cover a distance of 1895 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Myrtle Beach to Mesa one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $156. Southwest flights start at $173 while deals on Delta start at $188 one-way.

  • Can I find deals for flights from Myrtle Beach to Mesa that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Mesa.

  • Can I find deals for business class flights from Myrtle Beach to Mesa?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Mesa?

    Currently, April is the cheapest month in which you can book a flight from Myrtle Beach to Mesa (average of $198). Flying from Myrtle Beach to Mesa in November is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Myrtle Beach to Mesa

Discover the top 3 airlines that operate flights from Myrtle Beach to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$306Average$478FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$324Average$450FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$358Average$497FlexibilityNo cancel feeOn-time63%

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