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$100+ Cheap flights from Santo Domingo (SDQ) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — MDE
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Medellín are usually found in February or March, booked 55 days in advance, depart on a Monday or Saturday and return on a Wednesday

Cheap flight deals from Santo Domingo to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$209
(CheapOair)

One-way from

$100
(Wingo)

Popular in

December

Cheapest in

February

Average price

$263
From Santo Domingo Las Americas to Medellín
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One-way flight from Santo Domingo Las Americas to Medellín
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Highest demand for flights based on searches. 2% potential increase in price ($6 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santo Domingo to Medellín

Cheapest flights from Santo Domingo to Medellín
Explore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:07 pmSDQ - MDE
Nonstop2h 35mArajet
Wed 10/298:25 pmMDE - SDQ
Nonstop2h 32mArajet
Deal found 9/16$209
This Orbitz deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:48 amSDQ - MDE
Nonstop2h 32mArajet
Fri 11/218:25 pmMDE - SDQ
Nonstop2h 32mArajet
Deal found 9/16$210
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/209:40 amSDQ - MDE
Nonstop2h 35mArajet
Fri 10/249:27 pmMDE - SDQ
Nonstop2h 32mArajet
Deal found 9/16$211
This Orbitz deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/124:25 pmSDQ - MDE
Nonstop2h 35mArajet
Fri 10/179:27 pmMDE - SDQ
Nonstop2h 32mArajet
Deal found 9/16$218
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:55 amSDQ - MDE
Nonstop2h 35mArajet
Sun 10/126:45 pmMDE - SDQ
Nonstop2h 32mArajet
Deal found 9/16$221
This Wingo deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/252:33 pmSDQ - MDE
Nonstop2h 28mWingo
Sat 11/110:24 amMDE - SDQ
Nonstop2h 33mWingo
Deal found 9/15$224
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/42:33 pmSDQ - MDE
Nonstop2h 28mWingo
Sat 10/1110:13 amMDE - SDQ
Nonstop2h 30mWingo
Deal found 9/15$227
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:08 pmSDQ - MDE
Nonstop2h 32mArajet
Tue 11/410:17 amMDE - SDQ
Nonstop2h 32mArajet
Deal found 9/14$230
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:00 amSDQ - MDE
Nonstop2h 32mArajet
Sat 12/1310:05 amMDE - SDQ
Nonstop2h 32mArajet
Deal found 9/16$232

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Santo Domingo to Medellín that are best for you.

Fly from

Santo Domingo

Fly to

Medellín

Route

Depart

Return

Price

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 12/6

7:48 am-9:20 am

Nonstop2h 32m

Medellín Jose Maria Cordova Intl

Tue 12/9

10:17 am-1:49 pm

Nonstop2h 32m

$210

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Wed 1/14

6:08 pm-7:40 pm

Nonstop2h 32m

Medellín Jose Maria Cordova Intl

Mon 1/19

8:25 pm-11:57 pm

Nonstop2h 32m

$214

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 2/19

7:32 pm-9:02 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Sat 2/28

10:24 am-1:57 pm

Nonstop2h 33m

$218

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 10/30

7:32 pm-9:02 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Thu 11/6

3:09 pm-6:42 pm

Nonstop2h 33m

$218

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Tue 3/10

4:12 pm-5:42 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Tue 3/17

11:49 am-3:22 pm

Nonstop2h 33m

$218

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 10/25

2:33 pm-4:01 pm

Nonstop2h 28m

Medellín Jose Maria Cordova Intl

Sat 11/1

10:24 am-1:57 pm

Nonstop2h 33m

$233

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 11/22

2:47 pm-4:17 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Sat 11/29

10:24 am-1:57 pm

Nonstop2h 33m

$240

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 11/27

7:32 pm-9:02 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Tue 12/2

11:49 am-3:22 pm

Nonstop2h 33m

$243

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 11/15

2:47 pm-4:17 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Sat 11/22

10:24 am-1:57 pm

Nonstop2h 33m

$245

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 11/22

2:47 pm-4:17 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Tue 11/25

11:49 am-3:22 pm

Nonstop2h 33m

$258

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 21 results
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Best time to book a flight from Santo Domingo to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Medellín

How far ahead should I book a flight from Santo Domingo to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Medellín. Price data was last updated on September 12, 2025.

The price you pay for your flight from Santo Domingo to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 55 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santo Domingo to Medellín?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $378). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to MDE?

Find hourly flight availability from Santo Domingo to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Medellín at noon. If you’re flexible enough to do this you can expect to save up to 9% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Santo Domingo to Medellín?

Use this chart to determine the cheapest time to fly round-trip from Santo Domingo to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Santo Domingo to Medellín flight should consider departing on Wednesday at noon when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated September 16, 2025.
See what other customers who have flown with Copa Airlines and Avianca from Santo Domingo to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Food

6.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Food

6.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Food

6.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to Medellín?

    For a flight from Santo Domingo to Medellín, you will be flying from Las Americas. Santo Domingo Las Americas (SDQ) is just 17.5 mi from the center of the city. Las Americas is the only Santo Domingo airport and it handles 0 outbound flights to Medellín per day. 4 airlines have flights to Medellín from Santo Domingo Las Americas on a regular basis.

  • How long is the flight from Santo Domingo to Medellín?

    Arajet and Wingo can get you from Santo Domingo to Medellín in just under 2h 30m. Your travel time will be generally consistent. There are 931 mi between Santo Domingo and Medellín. Generally, flights for this route are nonstop.

  • What are the cheapest airlines flying from Santo Domingo to Medellín round-trip?

    Flying on Wingo is currently your cheapest option to Medellín, with prices starting at $115. Additional round-trip tickets that might be worth considering are offered by Copa Airlines and Arajet, with the lowest prices starting at $176 and $198, respectively. You may be able to fly from Santo Domingo to Medellín for 56% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Santo Domingo to Medellín?

    The top 3 most reliable airlines when flying from Santo Domingo to Medellín are Arajet (87%), Wingo (81%) and Euroairlines (76%).

  • What are the cheapest flights from Santo Domingo to Medellín?

    On average you can expect to pay $206 for a flight from Santo Domingo to Medellín. The cheapest flight overall is $103 while the most popular route, (Santo Domingo Las Americas - Medellín Jose Maria Cordova Intl) is currently priced at $210.

  • Can I find deals for flights from Santo Domingo to Medellín that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Medellín.

  • Can I find deals for business class flights from Santo Domingo to Medellín?

    Yes. Cheapflights offers flight deals from Santo Domingo to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Medellín?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $378). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Santo Domingo to Medellín

Discover the top 4 airlines that operate flights from Santo Domingo to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$115Average$257FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$176Average$264FlexibilityNo cancel feeOn-time70%
ArajetCheapest$198Average$278FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$238Average$398FlexibilityNo cancel feeOn-time71%

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