$118+ Cheap flights from Santo Domingo (SDQ) to Medellín
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — MDE
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Santo Domingo to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Santo Domingo Las Americas to Medellín are usually found in February or May, booked 77 days in advance, depart on a Saturday or Tuesday and return on a Thursday
Cheap flight deals from Santo Domingo to Medellín
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santo Domingo to MedellínExplore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:10 pm -
Nonstop2h 30m
Fri 11/2010:00 am -
Nonstop2h 32m
Deal found 9/13![Arajet logo]()
$247
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:14 pm -
Nonstop2h 28m
Tue 10/2011:54 am -
Nonstop2h 30m
Deal found 9/11![Wingo logo]()
$250
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:45 am -
Nonstop2h 30m
Fri 12/1110:00 am -
Nonstop2h 32m
Deal found 9/10![Arajet logo]()
$251
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:09 pm -
Nonstop2h 30m
Tue 11/1711:48 am -
Nonstop2h 31m
Deal found 9/11![Wingo logo]()
$253
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:06 pm -
Nonstop2h 30m
Tue 11/244:21 pm -
Nonstop2h 32m
Deal found 9/11![Arajet logo]()
$254
This Arajet deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:10 am -
1 stop9h 28m
Tue 11/34:21 pm -
Nonstop2h 32m
Deal found 9/11![Multiple Airlines logo]()
$256
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:14 pm -
Nonstop2h 28m
Tue 10/1311:54 am -
Nonstop2h 30m
Deal found 9/11![Wingo logo]()
$257
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:10 pm -
Nonstop2h 30m
Fri 11/278:25 pm -
Nonstop2h 32m
Deal found 9/10![Arajet logo]()
$259
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:42 pm -
Nonstop2h 28m
Sat 10/2410:22 am -
Nonstop2h 30m
Deal found 9/11![Wingo logo]()
$260
This Wingo deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:42 pm -
Nonstop2h 28m
Tue 9/2211:54 am -
Nonstop2h 30m
Deal found 9/14![Wingo logo]()
$264
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:45 am -
Nonstop2h 35m
Fri 11/68:25 pm -
Nonstop2h 32m
Deal found 9/10![Arajet logo]()
$265
This Wingo deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:43 pm -
Nonstop2h 30m
Sat 11/2810:22 am -
Nonstop2h 31m
Deal found 9/10![Wingo logo]()
$267
Best flights from Santo Domingo to MedellínDiscover carefully curated flight deals from Santo Domingo to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Santo Domingo to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Wingo deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/282:43 pm -
Nonstop2h 30m
Sat 12/510:22 am -
Nonstop2h 31m
Deal found 9/14![Wingo logo]()
$253
This Arajet deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/103:55 am -
1 stop10h 16m
Thu 2/181:56 pm -
1 stop6h 44m
Deal found 9/14![Multiple Airlines logo]()
$276
This Copa Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:55 am -
1 stop6h 00m
Mon 11/1610:45 am -
1 stop11h 13m
Deal found 9/13![Copa Airlines logo]()
$298
This Wingo deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:09 pm -
Nonstop2h 30m
Tue 11/1711:48 am -
Nonstop2h 31m
Deal found 9/10![Wingo logo]()
$253
This Arajet deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:10 am -
1 stop9h 35m
Fri 10/98:25 pm -
Nonstop2h 32m
Deal found 9/11![Multiple Airlines logo]()
$287
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:55 am -
1 stop6h 20m
Mon 11/305:00 am -
1 stop16h 58m
Deal found 9/10![Copa Airlines logo]()
$298
This Wingo deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:09 pm -
Nonstop2h 30m
Sat 10/3110:22 am -
Nonstop2h 31m
Deal found 9/12![Wingo logo]()
$277
This Copa Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:16 pm -
1 stop20h 24m
Wed 10/289:15 am -
1 stop5h 59m
Deal found 9/13![Copa Airlines logo]()
$298
This Copa Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:41 pm -
1 stop17h 14m
Mon 10/194:30 pm -
1 stop8h 55m
Deal found 9/13![Copa Airlines logo]()
$298
Last-minute flights from Santo Domingo to MedellínDiscover last-minute flight deals from Santo Domingo to Medellín. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to Medellín. Data last updated September 15, 2026 and is based on user searches.
This Wingo deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:42 pm -
Nonstop2h 28m
Tue 9/2211:54 am -
Nonstop2h 30m
Deal found 9/14![Wingo logo]()
$264
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:45 am -
Nonstop2h 35m
Tue 9/2910:05 am -
Nonstop2h 32m
Deal found 9/11![Arajet logo]()
$259
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:45 am -
Nonstop2h 35m
Tue 10/134:27 pm -
Nonstop2h 32m
Deal found 9/10![Arajet logo]()
$247
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:14 pm -
Nonstop2h 28m
Tue 10/2011:54 am -
Nonstop2h 30m
Deal found 9/11![Wingo logo]()
$250
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:14 pm -
Nonstop2h 28m
Tue 10/1311:54 am -
Nonstop2h 30m
Deal found 9/11![Wingo logo]()
$257
This Arajet deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:45 am -
Nonstop2h 35m
Tue 10/204:27 pm -
Nonstop2h 32m
Deal found 9/10![Arajet logo]()
$267
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:42 pm -
Nonstop2h 28m
Tue 10/2011:54 am -
Nonstop2h 30m
Deal found 9/11![Wingo logo]()
$253
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:42 pm -
Nonstop2h 28m
Sat 10/2410:22 am -
Nonstop2h 30m
Deal found 9/11![Wingo logo]()
$260
This Arajet deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:10 am -
1 stop9h 28m
Tue 11/34:21 pm -
Nonstop2h 32m
Deal found 9/11![Multiple Airlines logo]()
$256
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:05 pm -
Nonstop2h 35m
Fri 11/610:00 am -
Nonstop2h 32m
Deal found 9/11![Arajet logo]()
$254
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:45 am -
Nonstop2h 35m
Fri 11/68:25 pm -
Nonstop2h 32m
Deal found 9/10![Arajet logo]()
$265
One-way flights from Santo Domingo to MedellínSearch for one-way flight options from Santo Domingo to Medellín. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Santo Domingo to Medellín. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:14 pm -
Nonstop2h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Wingo logo]()
$118
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:42 pm -
Nonstop2h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Wingo logo]()
$122
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:45 am -
Nonstop2h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Arajet logo]()
$127
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:05 pm -
Nonstop2h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Arajet logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:45 am -
Nonstop2h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Arajet logo]()
$132
This Booking.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:22 am -
Nonstop2h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Arajet logo]()
$133
This Arajet deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:10 am -
1 stop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$135
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:05 pm -
Nonstop2h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Arajet logo]()
$136
This Arajet deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:45 am -
Nonstop2h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Arajet logo]()
$137
This Wingo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:14 pm -
Nonstop2h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Wingo logo]()
$140
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:05 pm -
Nonstop2h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Arajet logo]()
$144
Find flight deals from Santo Domingo to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Round-trip from | $247 (CheapOair) |
|---|---|
One-way from | $118 (Wingo) |
Popular in | December |
Cheapest in | February |
Average price | $274 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Santo Domingo to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Sat 10/24
2:42 pm-4:10 pm
Nonstop2h 28m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$118
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Tue 10/6
4:14 pm-5:42 pm
Nonstop2h 28m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$118
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Tue 10/27
4:09 pm-5:39 pm
Nonstop2h 30m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$122
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Wed 1/13
3:55 am-1:11 pm
1 stop10h 16m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$135
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Fri 2/19
8:55 am-3:45 pm
1 stop7h 50m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$135
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Tue 3/9
5:10 am-1:20 pm
1 stop9h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$135
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Tue 10/6
5:10 am-1:45 pm
1 stop9h 35m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$135
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Thu 1/14
7:20 pm-8:50 pm
Nonstop2h 30m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$136
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Tue 9/22
7:45 am-9:20 am
Nonstop2h 35m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$138
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Tue 10/13
4:14 pm-5:42 pm
Nonstop2h 28m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$140
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Santo Domingo to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from Santo Domingo with our price prediction graph.
SDQ-CO1
SDQ-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santo Domingo to Medellín
SDQ-CO1
SDQ-MDE
What is the cheapest month to book a flight from Santo Domingo to Medellín?
Currently, February is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $244). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDQ to MDE?
Find hourly flight availability from Santo Domingo to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2026.
A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Medellín at noon. If you’re flexible enough to do this you can expect to save up to 12% on your trip compared to booking a flight in the morning.
How much does it cost to fly round-trip from Santo Domingo to Medellín?
Airfare is typical for this route at the moment.
Santo Domingo to Medellín flights typically cost between $242 and $312 in January.The cheapest round-trip price found within the last 5 days was $247 on Arajet (Jan 13-Jan 20).
How often are flights from Santo Domingo to Medellín delayed?
About 17% of weekly flights between Santo Domingo and Medellín have experienced delays in the past year, with the average delay time being 151 minutes.
What is the most punctual flight time for Santo Domingo to Medellín flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Santo Domingo to Medellín flights?
Over the last year, Wingo have had the lowest number of delays on this route, with just 11% of flights being delayed.
How far ahead should I book a flight from Santo Domingo to Medellín?
The price you pay for your flight from Santo Domingo to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 76 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated September 15, 2026.
See what other customers who have flown with Copa Airlines and Avianca from Santo Domingo to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Boarding
7.8
Entertainment
6.9
Comfort
7.4
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Boarding
7.8
Entertainment
6.9
Comfort
7.4
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Boarding
7.8
Entertainment
6.9
Comfort
7.4
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
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Top 4 airlines flying from Santo Domingo to Medellín
Discover the top 4 airlines that operate flights from Santo Domingo to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$120 | Average$256 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$132 | Average$428 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$146 | Average$267 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$210 | Average$307 | FlexibilityNo cancel fee | On-timeN/A |