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$96+ Cheap flights from Santo Domingo (SDQ) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — MDE
Mar 10 — Mar 171
Tue 3/10
Tue 3/17
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Medellín are usually found in February or September, booked 90 days in advance, depart on a Saturday or Thursday and return on a Tuesday

Cheap flight deals from Santo Domingo to Medellín

Cheapest flights from Santo Domingo to Medellín
Explore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.

This Travelocity deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:58 pm
SDQ
-
MDE
Nonstop2h 32m
Arajet
Tue 3/244:15 pm
MDE
-
SDQ
Nonstop2h 32m
Arajet
Deal found 2/8$205
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:31 pm
SDQ
-
MDE
Nonstop2h 30m
Wingo
Tue 3/1711:49 am
MDE
-
SDQ
Nonstop2h 33m
Wingo
Deal found 2/5$212
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:23 am
SDQ
-
MDE
Nonstop2h 28m
Wingo
Tue 4/146:00 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 2/5$213
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:23 am
SDQ
-
MDE
Nonstop2h 28m
Wingo
Sat 8/110:24 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 2/5$215
This Wingo deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:32 pm
SDQ
-
MDE
Nonstop2h 30m
Wingo
Tue 3/1011:49 am
MDE
-
SDQ
Nonstop2h 33m
Wingo
Deal found 2/6$217
This Wingo deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:12 pm
SDQ
-
MDE
Nonstop2h 30m
Wingo
Tue 2/2411:49 am
MDE
-
SDQ
Nonstop2h 33m
Wingo
Deal found 2/5$226
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:31 pm
SDQ
-
MDE
Nonstop2h 30m
Wingo
Sat 3/144:08 pm
MDE
-
SDQ
Nonstop2h 33m
Wingo
Deal found 2/7$227
This Wingo deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:23 am
SDQ
-
MDE
Nonstop2h 28m
Wingo
Thu 5/76:00 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 2/8$228
This Wingo deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:12 pm
SDQ
-
MDE
Nonstop2h 30m
Wingo
Sat 3/144:08 pm
MDE
-
SDQ
Nonstop2h 33m
Wingo
Deal found 2/7$229
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:32 pm
SDQ
-
MDE
Nonstop2h 30m
Wingo
Tue 2/2411:49 am
MDE
-
SDQ
Nonstop2h 33m
Wingo
Deal found 2/6$234

Find flight deals from Santo Domingo to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 8, 2026.

Round-trip from

$205
(Travelocity)

One-way from

$96
(Wingo)

Popular in

December

Cheapest in

February

Average price

$240
From Santo Domingo Las Americas to Medellín
Search Deals
One-way flight from Santo Domingo Las Americas to Medellín
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Santo Domingo to Medellín that are best for you.

Fly from

Santo Domingo

Fly to

Medellín

Route

Depart

Return

Price

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 3/5

7:32 pm-9:02 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Tue 3/10

11:49 am-3:22 pm

Nonstop2h 33m

$217

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Tue 3/17

4:12 pm-5:42 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Thu 3/19

3:09 pm-6:42 pm

Nonstop2h 33m

$217

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 2/21

2:47 pm-4:17 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Sat 3/7

10:24 am-1:57 pm

Nonstop2h 33m

$217

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 4/9

10:23 am-11:51 am

Nonstop2h 28m

Medellín Jose Maria Cordova Intl

Tue 4/14

6:00 am-9:30 am

Nonstop2h 30m

$217

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 5/30

2:47 pm-4:15 pm

Nonstop2h 28m

Medellín Jose Maria Cordova Intl

Sat 6/13

10:24 am-1:54 pm

Nonstop2h 30m

$217

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Tue 3/10

4:12 pm-5:42 pm

Nonstop2h 30m

Medellín Jose Maria Cordova Intl

Tue 3/17

11:49 am-3:22 pm

Nonstop2h 33m

$217

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 4/16

10:23 am-11:51 am

Nonstop2h 28m

Medellín Jose Maria Cordova Intl

Tue 4/21

6:00 am-9:30 am

Nonstop2h 30m

$226

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 3/12

7:32 pm-9:02 pm

Nonstop2h 30m

$96

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 3/7

2:47 pm-4:17 pm

Nonstop2h 30m

$96

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 3/21

8:31 pm-10:01 pm

Nonstop2h 30m

$96

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/6

Showing 1-10 of 13 results
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Best time to book a flight from Santo Domingo to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Medellín

How far ahead should I book a flight from Santo Domingo to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Medellín. Price data was last updated on February 6, 2026.

The price you pay for your flight from Santo Domingo to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santo Domingo to Medellín?

Currently, November is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $112). Flying from Santo Domingo to Medellín in March is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to MDE?

Find hourly flight availability from Santo Domingo to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 8, 2026.

A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Medellín at noon. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the morning.

How often are flights from Santo Domingo to Medellín delayed?

About 13% of weekly flights between Santo Domingo and Medellín have experienced delays in the past year, with the average delay time being 139 minutes.

What is the most punctual flight time for Santo Domingo to Medellín flights?

Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Santo Domingo to Medellín flights?

Over the last year, Wingo have had the lowest number of delays on this route, with just 7% of flights being delayed.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated February 8, 2026.
See what other customers who have flown with Copa Airlines and Avianca from Santo Domingo to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,557 reviews

Entertainment

6.8

Crew

8.1

Food

6.8

Overall

7.5

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.5
Good
1,557 reviews
Copa Airlines
7.5
Good
1,557 reviews

Entertainment

6.8

Crew

8.1

Food

6.8

Overall

7.5

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Avianca
6.5
Okay
2,496 reviews
Copa Airlines
7.5
Good
1,557 reviews

Entertainment

6.8

Crew

8.1

Food

6.8

Overall

7.5

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to Medellín?

    For a flight from Santo Domingo to Medellín, you will be flying from Las Americas. Santo Domingo Las Americas (SDQ) is just 17.5 mi from the center of the city. Las Americas is the only Santo Domingo airport and it handles 1 outbound flight to Medellín per day. 4 airlines have flights to Medellín from Santo Domingo Las Americas on a regular basis.

  • How long is the flight from Santo Domingo to Medellín?

    Wingo can get you from Santo Domingo to Medellín in just under 2h 30m. Your travel time will be generally consistent. There are 931 mi between Santo Domingo and Medellín. Generally, flights for this route are nonstop.

  • What are the cheapest airlines flying from Santo Domingo to Medellín round-trip?

    Flying on Wingo is currently your cheapest option to Medellín, with prices starting at $101. Additional round-trip tickets that might be worth considering are offered by Avianca and Copa Airlines, with the lowest prices starting at $132 and $144, respectively. You may be able to fly from Santo Domingo to Medellín for 61% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Santo Domingo to Medellín one-way?

    For one-way options, check prices for Wingo. According to our data, you can fly for as low as $98. Users have also found prices from $103 and $127 on Arajet and Avianca, respectively.

  • What are the most reliable airlines from Santo Domingo to Medellín?

    The top 3 most reliable airlines when flying from Santo Domingo to Medellín are Wingo (83%), Euroairlines (62%) and Arajet (48%).

  • What are the cheapest flights from Santo Domingo to Medellín?

    On average you can expect to pay $202 for a flight from Santo Domingo to Medellín. The cheapest flight overall is $93 while the most popular route, (Santo Domingo Las Americas - Medellín Jose Maria Cordova Intl) is currently priced at $213.

  • Can I find deals for flights from Santo Domingo to Medellín that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Medellín.

  • Can I find deals for business class flights from Santo Domingo to Medellín?

    Yes. Cheapflights offers flight deals from Santo Domingo to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Medellín?

    Currently, November is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $112). Flying from Santo Domingo to Medellín in March is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Santo Domingo to Medellín

Discover the top 4 airlines that operate flights from Santo Domingo to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$101Average$248FlexibilityNo cancel feeOn-time83%
AviancaCheapest$132Average$353FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$144Average$264FlexibilityNo cancel feeOn-time70%
ArajetCheapest$188Average$288FlexibilityNo cancel feeOn-timeN/A

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