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Manchester

$267+ Cheap flights from South Carolina to Manchester (MAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
Mar 4 — Mar 111
Wed 3/4
Wed 3/11
1 adult, Economy
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Cheap flight deals from South Carolina to Manchester

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:47 pm
CHS
-
MAN
2 stops17h 23m
Air France
Wed 3/251:30 pm
MAN
-
CHS
1 stop14h 25m
Air France
Deal found 2/1$620
This Expedia deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:16 pm
MYR
-
MAN
2 stops14h 04m
KLM
Tue 3/241:30 pm
MAN
-
MYR
1 stop14h 34m
KLM
Deal found 1/31$627
This Cheapflightsfares deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:40 pm
CLT
-
MAN
1 stop17h 25m
Lufthansa
Thu 5/147:00 am
MAN
-
CLT
1 stop14h 45m
Lufthansa
Deal found 2/2$628
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:27 am
SAV
-
MAN
1 stop19h 03m
Delta
Tue 3/101:30 pm
MAN
-
SAV
1 stop14h 29m
Delta
Deal found 2/1$628
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:18 pm
CLT
-
MAN
2 stops13h 47m
British Airways
Thu 5/148:00 pm
MAN
-
CLT
2 stops24h 05m
British Airways
Deal found 2/2$629
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:59 am
SAV
-
MAN
2 stops17h 56m
American Airlines
Tue 3/109:40 am
MAN
-
SAV
2 stops17h 08m
American Airlines
Deal found 2/1$637
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/182:26 pm
CHS
-
MAN
1 stop16h 04m
Multiple Airlines
Wed 3/251:30 pm
MAN
-
CHS
1 stop23h 11m
Multiple Airlines
Deal found 2/1$642
This lastminute.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:23 am
MYR
-
MAN
2 stops17h 32m
Virgin Atlantic
Tue 3/245:05 pm
MAN
-
MYR
2 stops34h 59m
Virgin Atlantic
Deal found 1/31$646
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:50 am
SAV
-
MAN
2 stops20h 30m
United Airlines
Tue 3/246:10 am
MAN
-
SAV
2 stops17h 03m
United Airlines
Deal found 1/31$647
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/128:15 am
CHS
-
MAN
2 stops22h 05m
United Airlines
Wed 3/186:10 am
MAN
-
CHS
2 stops15h 54m
United Airlines
Deal found 2/1$647
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:55 pm
CLT
-
MAN
1 stop10h 55m
American Airlines
Thu 5/148:50 am
MAN
-
CLT
1 stop12h 00m
American Airlines
Deal found 2/2$650
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:57 pm
CLT
-
MAN
2 stops19h 33m
British Airways
Tue 9/88:05 pm
MAN
-
CLT
2 stops24h 00m
British Airways
Deal found 2/1$658

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated February 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$620
(Expedia)

One-way from

$267
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Manchester flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Manchester flights.
Search Deals
From South Carolina to Manchester
Search Deals
One-way flight from South Carolina to Manchester
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

South Carolina

Fly to

Manchester

Route

Depart

Return

Price

Myrtle BeachManchester

MYR - MAN

MYRMAN

Myrtle Beach Intl

Tue 3/17

2:16 pm-8:20 am

2 stops14h 04m

Manchester

Tue 3/24

1:30 pm-12:04 am

1 stop14h 34m

$627

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 3/4

10:27 am-10:30 am

1 stop19h 03m

Manchester

Tue 3/10

1:30 pm-11:59 pm

1 stop14h 29m

$628

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 5/6

4:34 pm-1:10 pm

2 stops15h 36m

Manchester

Thu 5/14

8:00 pm-3:05 pm

2 stops24h 05m

$629

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 3/4

11:59 am-10:55 am

2 stops17h 56m

Manchester

Tue 3/10

9:40 am-10:48 pm

2 stops17h 08m

$637

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 3/18

2:26 pm-10:30 am

1 stop16h 04m

Manchester

Wed 3/25

1:30 pm-8:41 am

1 stop23h 11m

$642

Myrtle BeachManchester

MYR - MAN

MYRMAN

Myrtle Beach Intl

Tue 3/17

10:23 am-7:55 am

2 stops17h 32m

Manchester

Tue 3/24

5:05 pm-12:04 am

2 stops34h 59m

$646

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Tue 3/17

9:50 am-10:20 am

2 stops20h 30m

Manchester

Tue 3/24

6:10 am-7:13 pm

2 stops17h 03m

$647

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 3/18

8:15 am-10:20 am

2 stops22h 05m

Manchester

Wed 3/25

6:10 am-10:04 am

2 stops31h 54m

$647

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 3/17

9:18 am-7:35 am

2 stops18h 17m

Manchester

Tue 3/24

8:05 am-11:53 pm

2 stops19h 48m

$668

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 3/1

9:54 am-7:55 am

2 stops17h 01m

Manchester

Tue 3/17

10:25 am-11:58 pm

2 stops17h 33m

$677

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 38 results
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of $491). Flying from South Carolina to Manchester in June is currently the most expensive (average of $899). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Manchester (MAN), located 8.9 mi from the city center, is the airport you fly into when you book flights from South Carolina to Manchester.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 14h 04m. KLM provides one of the quickest options available for as low as $627. The distance from South Carolina to Manchester is about 3864 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Manchester?

    The most popular route from South Carolina to Manchester is Charlotte Douglas - Manchester. You may also consider Greenville - Manchester or Myrtle Beach Intl - Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of $491). Flying from South Carolina to Manchester in June is currently the most expensive (average of $899). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Bury
Salford
Bolton
Barrow-in-Furness
Buxton
Huddersfield
Southport
Wakefield
Stockport
Derby
Bromborough
Lancaster
Llandudno
Conwy
Morecambe

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Alternative routes for South Carolina to Manchester

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Manchester

Discover the top 2 airlines that operate flights from South Carolina to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$655Average$1,090FlexibilityNo cancel feeOn-timeN/A
Virgin AtlanticCheapest$655Average$1,112FlexibilityNo cancel feeOn-time72%

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