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$249+ Cheap flights from South Carolina to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAD
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from South Carolina to Madrid

Cheapest flights from South Carolina to Madrid
Explore the most affordable flight options available from South Carolina to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amGSP - MAD
1 stop20h 00mDelta
Wed 12/1010:00 amMAD - GSP
2 stops17h 42mDelta
Deal found 11/1$428
This Virgin Atlantic deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:09 pmSAV - MAD
1 stop12h 06mVirgin Atlantic
Wed 12/1011:15 amMAD - SAV
1 stop15h 40mVirgin Atlantic
Deal found 11/2$438
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:00 amSAV - MAD
2 stops25h 10mMultiple Airlines
Wed 12/1012:10 pmMAD - SAV
2 stops30h 13mMultiple Airlines
Deal found 11/2$442
This KLM deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/112:51 pmCHS - MAD
1 stop14h 24mKLM
Mon 12/811:15 amMAD - CHS
1 stop16h 33mKLM
Deal found 11/2$463
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:45 pmCHS - MAD
1 stop30h 20mUnited Airlines
Mon 12/81:35 pmMAD - CHS
2 stops35h 55mUnited Airlines
Deal found 11/2$465
This Trip.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:30 pmSAV - MAD
1 stop32h 30mVirgin Atlantic
Wed 11/1210:00 amMAD - SAV
1 stop17h 19mVirgin Atlantic
Deal found 11/2$469
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/511:17 amSAV - MAD
2 stops16h 58mDelta
Wed 11/1211:15 amMAD - SAV
1 stop15h 45mDelta
Deal found 11/1$470
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:50 pmMYR - MAD
2 stops18h 50mDelta
Wed 11/1910:00 amMAD - MYR
2 stops29h 50mDelta
Deal found 11/2$474
This Air France deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:30 pmSAV - MAD
1 stop32h 30mKLM
Wed 11/1211:15 amMAD - SAV
1 stop18h 49mKLM
Deal found 11/1$478
This Finnair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:17 amSAV - MAD
1 stop17h 28mMultiple Airlines
Thu 11/201:15 pmMAD - SAV
1 stop12h 21mMultiple Airlines
Deal found 11/3$488
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:17 amCLT - MAD
3 stops28h 03mMultiple Airlines
Tue 12/910:20 amMAD - CLT
2 stops31h 44mMultiple Airlines
Deal found 11/2$496
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:50 pmCLT - MAD
1 stop17h 00mLufthansa
Tue 12/97:25 amMAD - CLT
1 stop15h 30mLufthansa
Deal found 11/2$497

Cheap flight deals from South Carolina to Madrid

Keep the following information in mind while searching for South Carolina to Madrid flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$428
(Delta)

One-way from

$249
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Madrid Barajas flights.
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From South Carolina to Madrid Barajas
Search Deals
One-way flight from South Carolina to Madrid Barajas
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from South Carolina to Madrid that are best for you.

Fly from

South Carolina

Fly to

Madrid

Route

Depart

Return

Price

GreenvilleMadrid

GSP - MAD

GSPMAD

Greenville

Mon 11/24

6:00 am-8:00 am

1 stop20h 00m

Madrid Barajas

Wed 12/10

10:00 am-9:42 pm

2 stops17h 42m

$428

SavannahMadrid

SAV - MAD

SAVMAD

Savannah/Hilton Head

Tue 12/2

10:00 am-5:10 pm

2 stops25h 10m

Madrid Barajas

Wed 12/10

12:10 pm-12:23 pm

2 stops30h 13m

$442

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 12/1

12:51 pm-9:15 am

1 stop14h 24m

Madrid Barajas

Mon 12/8

11:15 am-9:48 pm

1 stop16h 33m

$463

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 12/1

7:45 pm-8:05 am

1 stop30h 20m

Madrid Barajas

Mon 12/8

1:35 pm-7:30 pm

2 stops35h 55m

$465

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Tue 1/13

7:00 pm-8:00 am

2 stops31h 00m

Madrid Barajas

Sun 1/25

5:55 am-11:44 pm

2 stops23h 49m

$479

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Tue 1/13

10:18 am-5:45 am

1 stop13h 27m

Madrid Barajas

Sat 1/24

12:55 am-2:25 pm

1 stop19h 30m

$488

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Sun 1/11

10:59 am-8:55 am

1 stop15h 56m

Madrid Barajas

Sat 1/31

12:55 am-2:25 pm

1 stop19h 30m

$488

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Thu 1/8

12:29 pm-5:45 am

1 stop11h 16m

Madrid Barajas

Sun 2/15

10:00 am-7:25 pm

1 stop15h 25m

$488

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Thu 1/8

6:10 am-5:45 am

1 stop17h 35m

Madrid Barajas

Sat 2/14

12:55 am-11:48 am

1 stop16h 53m

$488

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Sun 1/11

7:45 pm-5:50 pm

2 stops16h 05m

Madrid Barajas

Sun 2/1

5:55 am-11:44 pm

2 stops23h 49m

$489

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 44 results
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Best time to book a flight from South Carolina to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Madrid

What is the cheapest month to book a flight from South Carolina to Madrid?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Madrid (average of $380). Flying from South Carolina to Madrid in June is currently the most expensive (average of $927). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MAD?

Find hourly flight availability from South Carolina to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Madrid in the afternoon. If you’re flexible enough to do this you can expect to save up to 25% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from South Carolina to Madrid?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Madrid. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Madrid flight should consider departing on Monday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Madrid from South Carolina?

    Madrid Barajas (MAD) is the airport you will fly into if you book a flight from South Carolina to Madrid. It is only a 8.5 mi journey from Barajas (MAD) to Madrid’s city center.

  • How long is the flight from South Carolina to Madrid?

    Airlines like Delta, KLM, and United Airlines fly from South Carolina to Madrid in about 14h 24m. The time it takes to get you to your destination can typically vary by up to 15h 56m. Airlines will cover a distance of 4134 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Madrid one-way?

    To fly one-way, consider booking your trip with Air Canada, which is currently one of the cheapest options available, starting at $390. Lufthansa flights start at $397 while deals on United Airlines start at $407 one-way.

  • What are the most popular routes from South Carolina to Madrid?

    While some choose either Charleston - Madrid Barajas or Greenville - Madrid Barajas, Charlotte Douglas - Madrid Barajas is the most popular route from South Carolina to Madrid.

  • Can I find deals for flights from South Carolina to Madrid that include hotel bookings?

    Yes. In addition to deals on South Carolina to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Madrid.

  • Can I find deals for business class flights from South Carolina to Madrid?

    Yes. Cheapflights offers flight deals from South Carolina to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Madrid?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Madrid (average of $380). Flying from South Carolina to Madrid in June is currently the most expensive (average of $927). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Fuenlabrada
Getafe

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Top 4 airlines flying from South Carolina to Madrid

Discover the top 4 airlines that operate flights from South Carolina to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$744FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$563Average$938FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$587Average$1,049FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$593Average$1,125FlexibilityNo cancel feeOn-time70%

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