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Lyon

$226+ Cheap flights from Mesa, AZ to Lyon (LYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — LYS
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Mesa to Lyon

Cheapest flights from Mesa to Lyon
Explore the most affordable flight options available from Mesa to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Air Canada deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:30 pm
PHX
-
LYS
2 stops32h 35m
Air Canada
Thu 3/2612:55 pm
LYS
-
PHX
2 stops35h 30m
Air Canada
Deal found 2/2$682
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/153:50 pm
PHX
-
LYS
1 stop17h 45m
Delta
Fri 3/276:55 am
LYS
-
PHX
2 stops22h 36m
Delta
Deal found 2/3$708
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:33 pm
PHX
-
LYS
2 stops30h 32m
United Airlines
Sun 3/291:55 pm
LYS
-
PHX
2 stops41h 20m
United Airlines
Deal found 2/2$723
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:36 am
PHX
-
LYS
2 stops18h 34m
United Airlines
Mon 3/910:40 am
LYS
-
PHX
2 stops37h 39m
United Airlines
Deal found 2/1$724
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1510:05 am
PHX
-
LYS
2 stops18h 55m
British Airways
Fri 3/279:10 pm
LYS
-
PHX
1 stop29h 10m
British Airways
Deal found 2/1$728
This Cheapflightsfares deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:33 am
PHX
-
LYS
2 stops27h 47m
Lufthansa
Mon 3/26:25 am
LYS
-
PHX
2 stops22h 26m
Lufthansa
Deal found 2/3$730
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:36 am
PHX
-
LYS
2 stops18h 34m
United Airlines
Sun 3/152:55 pm
LYS
-
PHX
2 stops27h 33m
United Airlines
Deal found 2/1$753
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/273:50 pm
PHX
-
LYS
1 stop22h 40m
Multiple Airlines
Mon 3/26:40 am
LYS
-
PHX
2 stops20h 24m
Multiple Airlines
Deal found 2/3$754

Find flight deals from Mesa to Lyon

Keep the following information in mind while searching for Mesa to Lyon flight deals. Data was last updated February 3, 2026.

Round-trip from

$682
(Air Canada)

One-way from

$226
(oojo)

Popular in

June

Cheapest in

February

Average price

$509
From Mesa to Lyon-Saint Exupéry
Search Deals
One-way flight from Mesa to Lyon-Saint Exupéry
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($241 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Mesa to Lyon that are best for you.

Fly from

Mesa

Fly to

Lyon

Route

Depart

Return

Price

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Sun 3/15

3:50 pm-5:35 pm

1 stop17h 45m

Lyon-Saint Exupéry

Fri 3/27

6:55 am-9:31 pm

2 stops22h 36m

$708

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Fri 3/20

7:33 pm-10:05 am

2 stops30h 32m

Lyon-Saint Exupéry

Sun 3/29

1:55 pm-10:15 pm

2 stops41h 20m

$723

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Thu 3/5

8:36 am-11:10 am

2 stops18h 34m

Lyon-Saint Exupéry

Mon 3/9

10:40 am-6:19 pm

2 stops39h 39m

$724

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Sun 3/15

10:05 am-1:00 pm

2 stops18h 55m

Lyon-Saint Exupéry

Fri 3/27

9:10 pm-6:20 pm

1 stop29h 10m

$728

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Fri 2/27

11:33 am-11:20 pm

2 stops27h 47m

Lyon-Saint Exupéry

Mon 3/2

10:40 am-9:42 pm

2 stops19h 02m

$732

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Thu 3/5

8:36 am-11:10 am

2 stops18h 34m

Lyon-Saint Exupéry

Mon 3/16

6:25 am-7:47 pm

2 stops21h 22m

$753

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Thu 3/5

8:36 am-11:10 am

2 stops18h 34m

Lyon-Saint Exupéry

Sun 3/15

2:55 pm-10:28 am

2 stops27h 33m

$753

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Fri 2/27

3:50 pm-10:30 pm

1 stop22h 40m

Lyon-Saint Exupéry

Mon 3/2

6:40 am-7:04 pm

2 stops20h 24m

$754

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Fri 3/20

3:50 pm-10:30 pm

1 stop22h 40m

Lyon-Saint Exupéry

Sun 3/29

9:00 am-1:10 pm

1 stop13h 10m

$754

PhoenixLyon

PHX - LYS

PHXLYS

Phoenix Sky Harbor Intl

Wed 5/13

4:58 pm-10:20 am

2 stops32h 22m

$226

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 11 results
1
2

Best time to book a flight from Mesa to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Lyon
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Lyon

Get insights into the airlines that provide service to Lyon. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lyon. Reviews last updated February 3, 2026.
Read reviews from past customers who have flown Delta, Air France, and British Airways from Mesa to Lyon. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,139 reviews

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,139 reviews
Delta
7.9
Good
8,139 reviews

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air France
7.4
Good
1,531 reviews
Delta
7.9
Good
8,139 reviews

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,712 reviews
Delta
7.9
Good
8,139 reviews

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lyon from Mesa?

    If you book a flight to Lyon from Mesa, you will be flying to Lyon-Saint Exupéry, which is the city’s only airport. Lyon-Saint Exupéry (LYS) is located 12.5 mi from the center of Lyon. There are 0 flights from Mesa to Lyon-Saint Exupéry per day from 3 different airlines.

  • How long is the flight from Mesa to Lyon?

    Departing from Mesa to Lyon will take you 17h 45m. Mesa and Lyon are separated by a distance of 5701 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mesa to Lyon that include hotel bookings?

    Yes. In addition to deals on Mesa to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Lyon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Lyon.

  • Can I find deals for business class flights from Mesa to Lyon?

    Yes. Cheapflights offers flight deals from Mesa to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Annemasse
Huez

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Alternative routes for Mesa to Lyon

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mesa to Lyon

Discover the top 3 airlines that operate flights from Mesa to Lyon. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$705Average$878FlexibilityNo cancel feeOn-time70%
Air FranceCheapest$722Average$1,120FlexibilityNo cancel feeOn-time77%
DeltaCheapest$784Average$1,244FlexibilityNo cancel feeOn-timeN/A

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