$478+ Cheap flights from Tampa (TPA) to Little Cayman (LYB)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — LYB
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tampa to Little Cayman
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Best
Last-minute
Cheapest flights from Tampa to Little CaymanExplore the most affordable flight options available from Tampa to Little Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Tampa to Little Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Cayman Airways deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cayman Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:15 pm -
1 stop19h 55m
Mon 11/28:50 am -
1 stop5h 40m
Deal found 9/15![Cayman Airways logo]()
$479
This Gotogate deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/283:30 pm -
1 stop23h 35m
Sat 1/23:45 pm -
1 stop22h 45m
Deal found 9/14![Cayman Airways logo]()
$669
This Justfly.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/294:00 pm -
2 stops39h 40m
Sat 1/23:45 pm -
1 stop22h 45m
Deal found 9/14![Multiple Airlines logo]()
$965
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2810:05 pm -
3 stops34h 30m
Sat 1/25:35 pm -
2 stops20h 55m
Deal found 9/14![Multiple Airlines logo]()
$1,171
Best flights from Tampa to Little CaymanDiscover carefully curated flight deals from Tampa to Little Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Tampa to Little Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Booking.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/283:30 pm -
1 stop16h 10m
Sun 1/317:50 am -
2 stops6h 40m
Deal found 9/12![Cayman Airways logo]()
$478
This Cayman Airways deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cayman Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:15 pm -
1 stop19h 55m
Mon 11/28:50 am -
1 stop5h 40m
Deal found 9/12![Cayman Airways logo]()
$479
Last-minute flights from Tampa to Little CaymanDiscover last-minute flight deals from Tampa to Little Cayman. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to Little Cayman. Data last updated September 17, 2026 and is based on user searches.
This Cayman Airways deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cayman Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:15 pm -
1 stop19h 55m
Mon 11/28:50 am -
1 stop5h 40m
Deal found 9/15![Cayman Airways logo]()
$479
Find flight deals from Tampa to Little Cayman
Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Little Cayman (LYB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Round-trip from | $448 (Trip.com) |
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Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to Little Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Tampa to Little Cayman that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
TampaLittle Cayman
TPA Tampa - LYB Little Cayman
TPALYB
Tampa
Thu 1/28
3:30 pm-7:40 am
1 stop16h 10m
Little Cayman
Sun 1/31
7:50 am-2:30 pm
2 stops6h 40m
$478
TampaLittle Cayman
TPA Tampa - LYB Little Cayman
TPALYB
Tampa
Fri 10/30
3:15 pm-10:10 am
1 stop19h 55m
Little Cayman
Mon 11/2
8:50 am-2:30 pm
1 stop5h 40m
$479
Sorted by cheapest first
Best time to book a flight from Tampa to Little Cayman
Have a flexible travel schedule? Discover the best time to fly to Little Cayman from Tampa with our price prediction graph.
TPA-LYB
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
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