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$492+ Cheap flights from Santiago (SCL) to Lisbon (LIS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — LIS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Lisbon Humberto Delgado are usually found in November or March, booked 58 days in advance, depart on a Tuesday or Thursday and return on a Tuesday

Cheap flight deals from Santiago to Lisbon

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Lisbon (LIS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$769
(KLM)

One-way from

$492
(British Airways)

Popular in

September

Cheapest in

November

Average price

$1,175
From Santiago Arturo Merino Benitez to Lisbon Humberto Delgado
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One-way flight from Santiago Arturo Merino Benitez to Lisbon Humberto Delgado
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Highest demand for flights based on searches. 1% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santiago to Lisbon

Cheapest flights from Santiago to Lisbon
Explore the most affordable flight options available from Santiago to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This KLM deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2210:40 amSCL - LIS
2 stops23h 55mMultiple Airlines
Mon 11/244:10 pmLIS - SCL
1 stop20h 30mMultiple Airlines
Deal found 9/12$769
This KLM deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/412:35 pmSCL - LIS
2 stops27h 15mMultiple Airlines
Tue 11/256:30 pmLIS - SCL
1 stop18h 10mMultiple Airlines
Deal found 9/14$774
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/412:35 pmSCL - LIS
2 stops27h 15mMultiple Airlines
Tue 11/186:30 pmLIS - SCL
1 stop18h 10mMultiple Airlines
Deal found 9/11$778
This LATAM Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/33:05 pmSCL - LIS
2 stops17h 15mLATAM Airlines
Fri 11/148:50 amLIS - SCL
1 stop16h 09mLATAM Airlines
Deal found 9/14$801
This LATAM Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/53:00 pmSCL - LIS
1 stop17h 20mLATAM Airlines
Wed 11/1912:30 pmLIS - SCL
2 stops30h 00mLATAM Airlines
Deal found 9/12$808
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2310:55 amSCL - LIS
2 stops31h 55mMultiple Airlines
Sun 11/306:30 pmLIS - SCL
1 stop18h 10mMultiple Airlines
Deal found 9/11$819
This Iberia deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:55 pmSCL - LIS
1 stop17h 10mIberia
Fri 1/166:30 amLIS - SCL
1 stop18h 45mIberia
Deal found 9/12$824

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Lisbon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Santiago to Lisbon that are best for you.

Fly from

Santiago

Fly to

Lisbon

Route

Depart

Return

Price

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Wed 10/22

10:40 am-6:40 pm

2 stops28h 00m

Lisbon Humberto Delgado

Mon 11/24

6:30 pm-9:40 am

1 stop18h 10m

$771

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Thu 10/23

10:55 am-10:50 pm

2 stops31h 55m

Lisbon Humberto Delgado

Sun 11/30

6:30 pm-9:40 am

1 stop18h 10m

$819

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Tue 2/3

10:45 pm-8:10 am

2 stops30h 25m

Lisbon Humberto Delgado

Tue 3/10

10:15 am-7:50 am

2 stops24h 35m

$890

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Thu 1/22

10:45 pm-8:10 am

2 stops30h 25m

Lisbon Humberto Delgado

Tue 3/3

10:15 am-8:50 am

2 stops25h 35m

$944

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Sun 10/5

9:25 am-11:05 pm

2 stops33h 40m

Lisbon Humberto Delgado

Tue 11/18

8:20 am-10:15 pm

1 stop16h 55m

$976

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Wed 12/24

11:55 pm-6:05 pm

1 stop15h 10m

Lisbon Humberto Delgado

Sat 1/10

6:40 pm-9:20 am

2 stops41h 40m

$1,005

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Thu 12/25

1:05 pm-6:05 pm

1 stop26h 00m

Lisbon Humberto Delgado

Mon 1/12

6:35 pm-9:20 am

2 stops41h 45m

$1,005

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Fri 12/26

11:55 pm-9:55 am

2 stops31h 00m

Lisbon Humberto Delgado

Fri 1/16

8:20 am-10:15 pm

1 stop16h 55m

$1,064

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Fri 12/26

11:55 pm-9:55 am

2 stops31h 00m

Lisbon Humberto Delgado

Mon 1/12

6:30 am-10:15 pm

1 stop18h 45m

$1,069

SantiagoLisbon

SCL - LIS

SCLLIS

Santiago Arturo Merino Benitez

Wed 10/29

1:05 pm-6:05 pm

1 stop26h 00m

$492

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 16 results
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Best time to book a flight from Santiago to Lisbon

Have a flexible travel schedule? Discover the best time to fly to Lisbon from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Lisbon

How far ahead should I book a flight from Santiago to Lisbon?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Lisbon. Price data was last updated on September 12, 2025.

The price you pay for your flight from Santiago to Lisbon may vary depending on when you book. For the best chance of a lower fare, look to book 58 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to Lisbon?

Currently, January is the cheapest month in which you can book a flight from Santiago to Lisbon (average of $612). Flying from Santiago to Lisbon in June is currently the most expensive (average of $1,127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to LIS?

Find hourly flight availability from Santiago to Lisbon. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

It’s optimal to fly from Santiago to Lisbon in the evening. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Santiago to Lisbon?

Reviews of airlines servicing Lisbon

Get insights into the airlines that provide service to Lisbon. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lisbon. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with LATAM Airlines from Santiago to Lisbon to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,847 reviews

Boarding

7.6

Entertainment

7.0

Crew

8.0

Food

6.7

Comfort

7.4

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
LATAM Airlines
7.5
Good
1,847 reviews
LATAM Airlines
7.5
Good
1,847 reviews

Boarding

7.6

Entertainment

7.0

Crew

8.0

Food

6.7

Comfort

7.4

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Lisbon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Lisbon?

    United Airlines can get you from Santiago to Lisbon in just under 30h 25m. Your travel time can differ by up to . Santiago and Lisbon are separated by a distance of 6355 mi.

  • What is the cheapest airline to fly from Santiago to Lisbon round-trip?

    Our cheapest airline available from Santiago to Lisbon is LATAM Airlines. Our recent data shows that you can find tickets from as low as $848 on this airline. Users have found that LATAM Airlines is 12% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Santiago to Lisbon one-way?

    For one-way options, check prices for Iberia. According to our data, you can fly for as low as $492. Users have also found prices from $577 and $583 on United Airlines and British Airways, respectively.

  • Can I find deals for flights from Santiago to Lisbon that include hotel bookings?

    Yes. In addition to deals on Santiago to Lisbon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Lisbon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Lisbon.

  • Can I find deals for business class flights from Santiago to Lisbon?

    Yes. Cheapflights offers flight deals from Santiago to Lisbon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Lisbon?

    Currently, January is the cheapest month in which you can book a flight from Santiago to Lisbon (average of $612). Flying from Santiago to Lisbon in June is currently the most expensive (average of $1,127). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lisbon?

Book flights to Lisbon if you plan to visit one of these locations
Sintra
Fátima
Oeiras
Beja
Nazaré
Ericeira
Costa da Caparica
Torres Vedras
Sesimbra
Colares

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Santiago to Lisbon

Discover the top airline that operate flights from Santiago to Lisbon. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$848Average$1,171FlexibilityNo cancel feeOn-time81%

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