How long is the flight from Missouri to Lafayette?

United Airlines, Delta, and American Airlines can get you from Missouri to Lafayette in just under 5h 32m. Your travel time can differ by up to 4h 26m. There are 493 mi between Missouri and Lafayette. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Lafayette ranges from 3.8 - 7.1 inches per month. June is typically the wettest month, when rainfall can reach 7.1 in. March is typically the driest time to visit Lafayette when rainfall is around 3.8 in.

If weather is an important factor for your trip to Lafayette, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What airport do you fly into for flights to Lafayette from Missouri?

Most people fly into Lafayette Regional (LFT) if they book a flight to Lafayette from Missouri. Lafayette Regional is conveniently located just 2.3 mi from Lafayette’s city center.

Can I find deals for flights from Missouri to Lafayette that include hotel bookings?

Yes. In addition to deals on Missouri to Lafayette flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Lafayette?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Lafayette.

Can I find deals for business class flights from Missouri to Lafayette?

Yes. Cheapflights offers flight deals from Missouri to Lafayette by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$259+ Flights from Missouri to Lafayette

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Cheap flight deals from Missouri to Lafayette

Cheapest flights from Missouri to Lafayette
Explore the most affordable flight options available from Missouri to Lafayette. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/312:04 pmSTL - LFT

1 stop7h 52mAmerican Airlines

Sun 1/45:26 amLFT - STL

1 stop5h 24mAmerican Airlines

Deal found 12/15

$603

Best flights from Missouri to Lafayette
Discover carefully curated flight deals from Missouri to Lafayette that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Thu 1/16:15 amSGF - LFT

1 stop5h 32mUnited Airlines

Mon 1/512:22 pmLFT - SGF

1 stop6h 05mUnited Airlines

Deal found 12/17

$259

Fri 1/239:59 amSTL - LFT

1 stop6h 36mDelta

Mon 1/265:15 pmLFT - STL

1 stop6h 22mDelta

Deal found 12/16

$269

Fri 1/2311:05 amSTL - LFT

2 stops9h 58mAmerican Airlines

Mon 1/266:33 pmLFT - STL

1 stop4h 22mAmerican Airlines

Deal found 12/17

$309

Wed 2/46:00 amSTL - LFT

1 stop4h 41mDelta

Mon 2/95:17 pmLFT - STL

1 stop6h 20mDelta

Deal found 12/16

$310

Fri 1/237:00 amSTL - LFT

2 stops12h 26mUnited Airlines

Mon 1/269:50 amLFT - STL

2 stops14h 09mUnited Airlines

Deal found 12/17

$349

Wed 2/46:00 amSTL - LFT

2 stops8h 20mAmerican Airlines

Mon 2/96:33 pmLFT - STL

1 stop4h 26mAmerican Airlines

Deal found 12/16

$379

Wed 1/143:00 pmSGF - LFT

1 stop6h 36mUnited Airlines

Sat 1/179:50 amLFT - SGF

2 stops10h 46mUnited Airlines

Deal found 12/16

$349

Tue 1/133:00 pmSGF - LFT

1 stop6h 36mUnited Airlines

Sat 1/179:50 amLFT - SGF

2 stops10h 46mUnited Airlines

Deal found 12/15

$349

Thu 1/17:00 amSTL - LFT

1 stop6h 24mAmerican Airlines

Mon 1/55:54 pmLFT - STL

1 stop5h 02mAmerican Airlines

Deal found 12/17

$419

Wed 1/73:00 pmSGF - LFT

1 stop6h 36mUnited Airlines

Fri 1/912:10 pmLFT - SGF

2 stops26h 28mUnited Airlines

Deal found 12/16

$408

Wed 1/712:26 pmSGF - LFT

2 stops10h 31mAmerican Airlines

Fri 1/92:50 pmLFT - SGF

1 stop4h 23mAmerican Airlines

Deal found 12/16

$480

Tue 1/66:00 amSTL - LFT

1 stop5h 27mUnited Airlines

Sat 1/105:20 amLFT - STL

2 stops12h 23mUnited Airlines

Deal found 12/15

$449

Wed 1/710:07 amSTL - LFT

1 stop7h 35mUnited Airlines

Sat 1/105:20 amLFT - STL

1 stop16h 40mUnited Airlines

Deal found 12/16

$466

Last-minute flights from Missouri to Lafayette
Discover last-minute flight deals from Missouri to Lafayette. Data last updated December 18, 2025 and is based on user searches.

Thu 1/16:15 amSGF - LFT

1 stop5h 32mUnited Airlines

Mon 1/512:22 pmLFT - SGF

1 stop6h 05mUnited Airlines

Deal found 12/17

$259

Thu 1/17:00 amSTL - LFT

1 stop6h 24mAmerican Airlines

Mon 1/55:54 pmLFT - STL

1 stop5h 02mAmerican Airlines

Deal found 12/17

$419

Thu 1/16:00 pmSGF - LFT

1 stop4h 52mAmerican Airlines

Mon 1/51:54 pmLFT - SGF

2 stops8h 34mAmerican Airlines

Deal found 12/17

$517

Tue 1/66:00 amSTL - LFT

1 stop5h 27mUnited Airlines

Sat 1/105:20 amLFT - STL

2 stops12h 23mUnited Airlines

Deal found 12/15

$449

Wed 1/73:00 pmSGF - LFT

1 stop6h 36mUnited Airlines

Fri 1/912:10 pmLFT - SGF

1 stop25h 48mUnited Airlines

Deal found 12/17

$408

Wed 1/78:05 amSTL - LFT

2 stops9h 37mUnited Airlines

Sat 1/1012:10 pmLFT - STL

1 stop9h 50mUnited Airlines

Deal found 12/16

$471

Wed 1/76:00 amSGF - LFT

1 stop4h 00mAmerican Airlines

Fri 1/96:00 amLFT - SGF

1 stop4h 20mAmerican Airlines

Deal found 12/16

$475

Tue 1/133:00 pmSGF - LFT

1 stop6h 36mUnited Airlines

Sat 1/179:50 amLFT - SGF

2 stops10h 46mUnited Airlines

Deal found 12/15

$349

Fri 1/236:00 amSTL - LFT

1 stop4h 41mDelta

Mon 1/265:15 pmLFT - STL

1 stop6h 22mDelta

Deal found 12/17

$269

Fri 1/2311:05 amSTL - LFT

2 stops6h 56mAmerican Airlines

Mon 1/266:33 pmLFT - STL

1 stop4h 22mAmerican Airlines

Deal found 12/16

$274

Fri 1/237:00 amSTL - LFT

2 stops12h 26mUnited Airlines

Mon 1/269:50 amLFT - STL

2 stops14h 09mUnited Airlines

Deal found 12/17

$349

One-way flights from Missouri to Lafayette
Search for one-way flight options from Missouri to Lafayette. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Wed 12/2411:41 amSTL - LFT

1 stop6h 33mAmerican Airlines

Deal found 12/17

$290

Find flight deals from Missouri to Lafayette

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$259 (United Airlines)
Popular in	September
Cheapest in	February
Average price	$407

Provider with most accurate pricing for Lambert-St Louis-Lafayette Regional flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Lafayette Regional flights.

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From Missouri to Lafayette Regional

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($66 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 8% potential price decrease ($29 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Lafayette that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SpringfieldLafayette

SGF - LFT

SGFLFT

Springfield-Branson

Thu 1/1

6:15 am-11:47 am

1 stop5h 32m

Lafayette Regional

Mon 1/5

12:22 pm-6:27 pm

1 stop6h 05m

$259

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Fri 1/23

9:59 am-4:35 pm

1 stop6h 36m

Lafayette Regional

Mon 1/26

5:15 pm-11:37 pm

1 stop6h 22m

$269

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Fri 1/23

11:05 am-9:03 pm

2 stops9h 58m

Lafayette Regional

Mon 1/26

6:33 pm-10:55 pm

1 stop4h 22m

$309

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Wed 2/4

6:00 am-10:41 am

1 stop4h 41m

Lafayette Regional

Mon 2/9

5:17 pm-11:37 pm

1 stop6h 20m

$310

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Fri 1/23

7:00 am-7:26 pm

2 stops12h 26m

Lafayette Regional

Mon 1/26

9:50 am-11:59 pm

2 stops14h 09m

$349

SpringfieldLafayette

SGF - LFT

SGFLFT

Springfield-Branson

Wed 1/14

3:00 pm-9:36 pm

1 stop6h 36m

Lafayette Regional

Sat 1/17

9:50 am-8:36 pm

2 stops10h 46m

$349

SpringfieldLafayette

SGF - LFT

SGFLFT

Springfield-Branson

Tue 1/13

3:00 pm-9:36 pm

1 stop6h 36m

Lafayette Regional

Sat 1/17

9:50 am-8:36 pm

2 stops10h 46m

$349

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Wed 2/4

6:00 am-2:20 pm

2 stops8h 20m

Lafayette Regional

Mon 2/9

6:33 pm-10:59 pm

1 stop4h 26m

$379

SpringfieldLafayette

SGF - LFT

SGFLFT

Springfield-Branson

Wed 1/7

3:00 pm-9:36 pm

1 stop6h 36m

Lafayette Regional

Fri 1/9

12:10 pm-2:38 pm

2 stops26h 28m

$408

St. LouisLafayette

STL - LFT

STLLFT

Lambert-St Louis

Thu 1/1

7:00 am-1:24 pm

1 stop6h 24m

Lafayette Regional

Mon 1/5

5:54 pm-10:56 pm

1 stop5h 02m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 14 results

Best time to book a flight from Missouri to Lafayette

Have a flexible travel schedule? Discover the best time to fly to Lafayette from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Lafayette

What is the cheapest month to book a flight from Missouri to Lafayette?

Currently, July is the cheapest month in which you can book a flight from Missouri to Lafayette (average of $180). Flying from Missouri to Lafayette in November is currently the most expensive (average of $311). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to LFT?

It’s optimal to fly from Missouri to Lafayette in the evening. By choosing this option you can save up to 37% on the cost of your flight, compared to a flight in the afternoon.

Related info for your journey

What airport do you fly into for flights to Lafayette from Missouri?
Most people fly into Lafayette Regional (LFT) if they book a flight to Lafayette from Missouri. Lafayette Regional is conveniently located just 2.3 mi from Lafayette’s city center.
How long is the flight from Missouri to Lafayette?
United Airlines, Delta, and American Airlines can get you from Missouri to Lafayette in just under 5h 32m. Your travel time can differ by up to 4h 26m. There are 493 mi between Missouri and Lafayette. This flight may include one or multiple stops.
Can I find deals for flights from Missouri to Lafayette that include hotel bookings?
Yes. In addition to deals on Missouri to Lafayette flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Lafayette?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Lafayette.
Can I find deals for business class flights from Missouri to Lafayette?
Yes. Cheapflights offers flight deals from Missouri to Lafayette by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Lafayette?
Currently, July is the cheapest month in which you can book a flight from Missouri to Lafayette (average of $180). Flying from Missouri to Lafayette in November is currently the most expensive (average of $311). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Missouri to Lafayette

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$198	Average$375	FlexibilityNo cancel fee	On-time71%

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$259+ Cheap flights from Missouri to Lafayette (LFT)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Lafayette with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missouri to Lafayette

Cheapest flights from Missouri to LafayetteExplore the most affordable flight options available from Missouri to Lafayette. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Missouri to Lafayette. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Missouri to Lafayette

Keep the following information in mind while searching for Missouri to Lafayette flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Lafayette that are best for you.

Best time to book a flight from Missouri to Lafayette

Have a flexible travel schedule? Discover the best time to fly to Lafayette from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Lafayette

What is the cheapest month to book a flight from Missouri to Lafayette?

What is the cheapest time of day to fly from MO to LFT?

Find hourly flight availability from Missouri to Lafayette. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Lafayette. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Lafayette from Missouri?

How long is the flight from Missouri to Lafayette?

Can I find deals for flights from Missouri to Lafayette that include hotel bookings?

How can I find direct flights from Missouri to Lafayette?

Can I find deals for business class flights from Missouri to Lafayette?

What is the cheapest month to book a flight from Missouri to Lafayette?

Traveling to a place near Lafayette?

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Alternative routes for Missouri to Lafayette

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Top airline flying from Missouri to Lafayette

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Cheapest flights from Missouri to Lafayette
Explore the most affordable flight options available from Missouri to Lafayette. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.