What are the cheapest airlines to fly from Detroit to Key Largo one-way?

The cheapest airlines for a one-way flight from Detroit to Key Largo are Frontier ($44), JetBlue ($117), and American Airlines ($118).

Weekly flight availability from Detroit to Key Largo

The most flights from DTT to KE9 are scheduled on a Saturday (19 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (13 on average).

In terms of precipitation, rainfall in Key Largo ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Key Largo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Key Largo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

What are the cheapest flights from Detroit to Key Largo?

Looking at all options, your cheapest flight can be booked for $158. While the most popular route (Detroit Metropolitan Wayne County - Miami) can be booked for $168 on average, our data indicates $1,048 when flying from Detroit to Key Largo.

What are the most reliable airlines from Detroit to Key Largo?

No one likes to see their flight delayed. When booking a flight from Detroit to Key Largo consider choosing Republic Airways (100%), Qatar Airways (93%) or American Airlines (90%) as they are the most reliable in getting you off to your destination on time.

What are the most popular airlines that fly from Detroit to Key Largo?

Consider Delta, American Airlines or Frontier when booking your flight. These represent the most popular airlines when flying from Detroit to Key Largo.

What airport do you fly from for flights from Detroit to Key Largo?

Most people fly from Detroit All airports (DTT) if they book a flight from Detroit to Key Largo. On average, All airports has 16 outbound flights to Key Largo per day from 6 airlines. Detroit All airports is conveniently located just 0.6 mi from Detroit’s city center.

Can I find deals for flights from Detroit to Key Largo that include hotel bookings?

Yes. In addition to deals on Detroit to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to Key Largo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Key Largo.

Can I find deals for business class flights from Detroit to Key Largo?

Yes. Cheapflights offers flight deals from Detroit to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Cheap Flights from Detroit to Key Largo

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Cheapflights Tip: The best prices from Detroit All airports to Key Largo are usually found in January or August, booked 90 days in advance, depart on a Monday or Sunday and return on a Thursday

Find flight deals from Detroit to Key Largo

Most accurate provider	FlightHub 3 stars
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Popular in	June
Cheapest in	January
Average price	$301

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Highest demand for flights based on searches. 10% potential increase in price ($37 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

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Average for round-trip flights in October 2026

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Everything you need to know about your flight from Detroit to Key Largo

Prices

Airlines

What is the cheapest time of day to fly from DTT to KE9?

A simple way to save on the total cost of your ticket is to fly from Detroit to Key Largo in the evening. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Detroit to Key Largo?

Travelers seeking maximum savings on their Detroit to Key Largo flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Read through reviews of airlines operating flights from Detroit to Key Largo, such as Southwest,Delta, andJetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,213 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Southwest

7.9

Good

4,213 reviews

Southwest

7.9

Good

4,213 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Delta

7.8

Good

8,650 reviews

Southwest

7.9

Good

4,213 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

JetBlue

7.1

Good

3,059 reviews

Southwest

7.9

Good

4,213 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

American Airlines

7.0

Good

12,181 reviews

Southwest

7.9

Good

4,213 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Frontier

5.5

Fair

2,524 reviews

Southwest

7.9

Good

4,213 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

What airport do you fly from for flights from Detroit to Key Largo?
Most people fly from Detroit All airports (DTT) if they book a flight from Detroit to Key Largo. On average, All airports has 16 outbound flights to Key Largo per day from 6 airlines. Detroit All airports is conveniently located just 0.6 mi from Detroit’s city center.
What are the cheapest airlines to fly from Detroit to Key Largo one-way?
The cheapest airlines for a one-way flight from Detroit to Key Largo are Frontier ($44), JetBlue ($117), and American Airlines ($118).
What are the most reliable airlines from Detroit to Key Largo?
No one likes to see their flight delayed. When booking a flight from Detroit to Key Largo consider choosing Republic Airways (100%), Qatar Airways (93%) or American Airlines (90%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Detroit to Key Largo?
Looking at all options, your cheapest flight can be booked for $158. While the most popular route (Detroit Metropolitan Wayne County - Miami) can be booked for $168 on average, our data indicates $1,048 when flying from Detroit to Key Largo.
Can I find deals for flights from Detroit to Key Largo that include hotel bookings?
Yes. In addition to deals on Detroit to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to Key Largo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Key Largo.
Can I find deals for business class flights from Detroit to Key Largo?
Yes. Cheapflights offers flight deals from Detroit to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 6 airlines flying from Detroit to Key Largo

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$59	Average$212	FlexibilityNo cancel fee	On-time62%
Southwest	Cheapest$158	Average$389	FlexibilityNo cancel fee	On-time63%
Delta	Cheapest$161	Average$396	FlexibilityNo cancel fee	On-timeN/A
JetBlue	Cheapest$175	Average$298	FlexibilityNo cancel fee	On-time62%
United Airlines	Cheapest$204	Average$392	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$211	Average$431	FlexibilityNo cancel fee	On-time71%

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Cheap flights from Detroit (DTT) to Key Largo, FL

Find cheap flights from Detroit to Key Largo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Detroit to Key Largo

Most accurate provider

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Popular in

Cheapest in

Average price

Cheapflights Insights

What is the cheapest time of day to fly from DTT to KE9?

A simple way to save on the total cost of your ticket is to fly from Detroit to Key Largo in the evening. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Detroit to Key Largo?

Travelers seeking maximum savings on their Detroit to Key Largo flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Detroit to Key Largo

The most flights from DTT to KE9 are scheduled on a Saturday (19 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (13 on average).

Reviews of airlines servicing Key Largo

Read through reviews of airlines operating flights from Detroit to Key Largo, such as Southwest,Delta, andJetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Detroit to Key Largo?

What are the cheapest airlines to fly from Detroit to Key Largo one-way?

What are the most reliable airlines from Detroit to Key Largo?

What are the cheapest flights from Detroit to Key Largo?

Can I find deals for flights from Detroit to Key Largo that include hotel bookings?

How can I find direct flights from Detroit to Key Largo?

Can I find deals for business class flights from Detroit to Key Largo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Detroit to Key Largo by cabin class

Find flights from Detroit to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Detroit and Key Largo flights

Browse other Detroit and Key Largo flight options. Last updated on October 20, 2026.

Other flights from Detroit

Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.

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Top 6 airlines flying from Detroit to Key Largo

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