$156+ Cheap flights from Missouri to Grand Cayman
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Grand Cayman with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Grand Cayman
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Best
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One-way
Cheapest flights from Missouri to Grand CaymanExplore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Air Canada deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:10 pm -
2 stops47h 15m
Sat 10/1011:25 am -
1 stop26h 35m
Deal found 9/6![Air Canada logo]()
$402
This Travelocity deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:05 pm -
1 stop19h 05m
Tue 11/241:10 pm -
1 stop27h 16m
Deal found 9/9![Air Canada logo]()
$412
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:00 am -
1 stop14h 00m
Fri 11/68:15 am -
1 stop14h 32m
Deal found 9/5![American Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:00 am -
1 stop8h 45m
Sun 12/138:15 am -
1 stop16h 44m
Deal found 9/5![American Airlines logo]()
$422
This Booking.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:40 pm -
1 stop19h 50m
Fri 10/3012:10 pm -
1 stop27h 13m
Deal found 9/8![Air Canada logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:01 am -
1 stop9h 24m
Wed 10/148:00 am -
1 stop14h 59m
Deal found 9/8![American Airlines logo]()
$455
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:15 am -
1 stop6h 20m
Fri 11/201:30 pm -
1 stop11h 20m
Deal found 9/8![Southwest logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:32 pm -
1 stop16h 58m
Thu 10/292:10 pm -
1 stop8h 49m
Deal found 9/7![American Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:30 pm -
1 stop6h 28m
Fri 12/1112:55 pm -
1 stop12h 04m
Deal found 9/6![American Airlines logo]()
$497
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:03 am -
2 stops12h 55m
Sun 12/208:30 am -
1 stop9h 13m
Deal found 9/5![American Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop5h 40m
Thu 10/2912:55 pm -
1 stop8h 19m
Deal found 9/6![Delta logo]()
$527
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:00 am -
1 stop6h 30m
Thu 10/298:00 am -
2 stops10h 20m
Deal found 9/6![American Airlines logo]()
$532
Best flights from Missouri to Grand CaymanDiscover carefully curated flight deals from Missouri to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Missouri to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:00 am -
1 stop14h 00m
Fri 11/68:15 am -
1 stop14h 32m
Deal found 9/5![American Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:15 am -
1 stop6h 20m
Fri 11/201:30 pm -
1 stop11h 20m
Deal found 9/8![Southwest logo]()
$467
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/196:00 am -
1 stop5h 40m
Tue 1/262:05 pm -
1 stop10h 34m
Deal found 9/7![Delta logo]()
$527
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:15 am -
1 stop9h 15m
Wed 11/45:45 pm -
2 stops19h 25m
Deal found 9/8![United Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:32 pm -
1 stop16h 58m
Thu 10/292:10 pm -
1 stop8h 49m
Deal found 9/7![American Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:05 am -
2 stops11h 53m
Fri 12/1112:55 pm -
1 stop12h 04m
Deal found 9/6![American Airlines logo]()
$502
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/196:00 am -
1 stop5h 40m
Mon 1/252:05 pm -
1 stop10h 34m
Deal found 9/7![Delta logo]()
$575
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:20 pm -
2 stops14h 15m
Tue 11/241:30 pm -
1 stop11h 25m
Deal found 9/6![Southwest logo]()
$608
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:19 am -
1 stop6h 06m
Wed 10/284:45 pm -
2 stops19h 38m
Deal found 9/8![United Airlines logo]()
$654
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/318:25 pm -
2 stops15h 10m
Wed 1/61:50 pm -
2 stops20h 35m
Deal found 9/7![Southwest logo]()
$628
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
2 stops13h 00m
Mon 10/192:10 pm -
2 stops10h 18m
Deal found 9/8![American Airlines logo]()
$601
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:39 pm -
2 stops17h 46m
Sun 9/271:35 pm -
2 stops19h 32m
Deal found 9/8![United Airlines logo]()
$672
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:40 pm -
2 stops15h 55m
Wed 1/61:50 pm -
2 stops18h 50m
Deal found 9/7![Southwest logo]()
$628
Last-minute flights from Missouri to Grand CaymanDiscover last-minute flight deals from Missouri to Grand Cayman. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Grand Cayman. Data last updated September 10, 2026 and is based on user searches.
This Air Canada deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:10 pm -
2 stops47h 15m
Sat 10/1011:25 am -
1 stop26h 35m
Deal found 9/6![Air Canada logo]()
$402
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:00 am -
1 stop5h 55m
Sat 10/102:10 pm -
1 stop7h 49m
Deal found 9/6![American Airlines logo]()
$575
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:01 am -
1 stop9h 24m
Wed 10/148:00 am -
1 stop14h 59m
Deal found 9/8![American Airlines logo]()
$455
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:10 pm -
1 stop17h 50m
Thu 10/152:10 pm -
1 stop8h 49m
Deal found 9/8![American Airlines logo]()
$573
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:01 am -
1 stop13h 59m
Fri 10/162:10 pm -
2 stops10h 18m
Deal found 9/8![American Airlines logo]()
$642
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:32 pm -
1 stop16h 58m
Mon 10/192:10 pm -
1 stop8h 49m
Deal found 9/8![American Airlines logo]()
$596
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:32 pm -
1 stop16h 58m
Thu 10/292:10 pm -
1 stop8h 49m
Deal found 9/7![American Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop5h 40m
Thu 10/2912:55 pm -
1 stop8h 19m
Deal found 9/6![Delta logo]()
$527
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
2 stops13h 00m
Thu 10/298:00 am -
2 stops10h 20m
Deal found 9/6![American Airlines logo]()
$532
This Booking.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:40 pm -
1 stop19h 50m
Fri 10/3012:10 pm -
1 stop27h 13m
Deal found 9/8![Air Canada logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:00 am -
2 stops14h 00m
Fri 10/3012:00 pm -
2 stops9h 59m
Deal found 9/8![American Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:00 am -
1 stop14h 00m
Fri 11/68:15 am -
1 stop14h 32m
Deal found 9/5![American Airlines logo]()
$417
One-way flights from Missouri to Grand CaymanSearch for one-way flight options from Missouri to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Missouri to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Air Canada deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:55 am -
1 stop25h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Air Canada logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:35 pm -
3 stops20h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:50 pm -
2 stops43h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:15 am -
1 stop6h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Southwest logo]()
$441
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:05 pm -
3 stops40h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$640
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/265:20 am -
1 stop8h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$973
Find flight deals from Missouri to Grand Cayman
Keep the following information in mind while searching for Missouri to Grand Cayman flight deals. Data was last updated September 10, 2026.
Round-trip from | $402 (Air Canada) |
|---|---|
One-way from | $156 (Air Canada) |
Popular in | June |
Cheapest in | April |
Average price | $627 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Missouri to Grand Cayman that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Fri 10/23
6:35 pm-2:50 pm
3 stops20h 15m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$275
Kansas CityGeorge Town
MCI Kansas City - GCM George Town Owen Roberts Intl
MCIGCM
Kansas City
Fri 11/20
5:50 pm-2:35 pm
2 stops43h 45m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$346
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Sat 10/31
5:00 am-7:00 pm
1 stop14h 00m
George Town Owen Roberts Intl
Fri 11/6
8:15 am-9:47 pm
1 stop14h 32m
$417
Quickest round-trip
Kansas CityGeorge Town
MCI Kansas City - GCM George Town Owen Roberts Intl
MCIGCM
Kansas City
Fri 11/20
5:15 am-12:35 pm
1 stop6h 20m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$441
Kansas CityGeorge Town
MCI Kansas City - GCM George Town Owen Roberts Intl
MCIGCM
Kansas City
Sun 11/15
5:15 am-12:35 pm
1 stop6h 20m
George Town Owen Roberts Intl
Fri 11/20
1:30 pm-11:50 pm
1 stop11h 20m
$467
Kansas CityGeorge Town
MCI Kansas City - GCM George Town Owen Roberts Intl
MCIGCM
Kansas City
Thu 10/22
6:32 pm-11:30 am
1 stop16h 58m
George Town Owen Roberts Intl
Thu 10/29
2:10 pm-10:59 pm
1 stop8h 49m
$496
Kansas CityGeorge Town
MCI Kansas City - GCM George Town Owen Roberts Intl
MCIGCM
Kansas City
Sat 12/5
7:05 am-7:58 pm
2 stops11h 53m
George Town Owen Roberts Intl
Fri 12/11
12:55 pm-11:59 pm
1 stop12h 04m
$502
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Tue 1/19
6:00 am-12:40 pm
1 stop5h 40m
George Town Owen Roberts Intl
Tue 1/26
2:05 pm-11:39 pm
1 stop10h 34m
$527
St. LouisGeorge Town
STL Lambert-St Louis - GCM George Town Owen Roberts Intl
STLGCM
Lambert-St Louis
Tue 1/19
6:00 am-12:40 pm
1 stop5h 40m
George Town Owen Roberts Intl
Mon 1/25
2:05 pm-11:39 pm
1 stop10h 34m
$575
Kansas CityGeorge Town
MCI Kansas City - GCM George Town Owen Roberts Intl
MCIGCM
Kansas City
Thu 10/15
6:00 am-7:00 pm
2 stops13h 00m
George Town Owen Roberts Intl
Mon 10/19
2:10 pm-12:28 am
2 stops10h 18m
$601
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Missouri to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Missouri with our price prediction graph.
STL-GCM
MCI-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Grand Cayman
USMO-zzLAW
STL-GCM
MCI-GCM
What is the cheapest month to book a flight from Missouri to Grand Cayman?
Currently, August is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $500). Flying from Missouri to Grand Cayman in June is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
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Popular flights
Alternative routes for Missouri to Grand Cayman
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Grand Cayman by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Grand Cayman by cabin class
Find flights from Missouri to Grand Cayman, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Grand Cayman flights
Browse other Missouri and Grand Cayman flight options. Last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Missouri to Grand Cayman
Discover the top 4 airlines that operate flights from Missouri to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$237 | Average$567 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$364 | Average$608 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$419 | Average$655 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$483 | Average$774 | FlexibilityNo cancel fee | On-time63% |