$157+ Cheap flights from Missouri to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — GCM
Jul 11 — Jul 181
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to Grand CaymanExplore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
Explore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:00 am
MCI
- GCM
1 stop6h 00m
American Airlines
Tue 8/182:10 pm
GCM
- MCI
1 stop8h 35m
American Airlines
Deal found 6/10![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am
STL
- GCM
1 stop6h 00m
American Airlines
Tue 8/252:10 pm
GCM
- STL
1 stop8h 30m
American Airlines
Deal found 6/10![American Airlines logo]()
$424
This Air Canada deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:15 pm
STL
- GCM
1 stop21h 10m
Air Canada
Sat 6/2010:55 am
GCM
- STL
1 stop25h 26m
Air Canada
Deal found 6/8![Air Canada logo]()
$432
This Orbitz deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:15 pm
STL
- GCM
1 stop19h 45m
Air Canada
Sat 11/71:10 pm
GCM
- STL
1 stop27h 20m
Air Canada
Deal found 6/10![Air Canada logo]()
$499
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:10 am
MCI
- GCM
1 stop9h 20m
United Airlines
Sat 12/52:50 pm
GCM
- MCI
1 stop7h 59m
United Airlines
Deal found 6/11![United Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:10 am
STL
- GCM
1 stop14h 05m
American Airlines
Tue 12/223:35 pm
GCM
- STL
1 stop9h 24m
American Airlines
Deal found 6/9![American Airlines logo]()
$504
This Air Canada deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:15 pm
STL
- GCM
1 stop19h 45m
Air Canada
Wed 11/41:10 pm
GCM
- STL
1 stop27h 20m
Air Canada
Deal found 6/9![Air Canada logo]()
$507
This Justfly.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:15 pm
STL
- GCM
1 stop19h 45m
Air Canada
Fri 11/61:10 pm
GCM
- STL
1 stop27h 20m
Air Canada
Deal found 6/10![Air Canada logo]()
$508
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:01 am
MCI
- GCM
1 stop5h 59m
American Airlines
Sun 8/232:10 pm
GCM
- MCI
1 stop9h 49m
American Airlines
Deal found 6/9![American Airlines logo]()
$509
This FlightHub deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:15 pm
STL
- GCM
1 stop18h 45m
Air Canada
Tue 12/81:10 pm
GCM
- STL
1 stop27h 20m
Air Canada
Deal found 6/7![Air Canada logo]()
$554
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:00 am
MCI
- GCM
1 stop11h 10m
American Airlines
Tue 8/112:10 pm
GCM
- MCI
2 stops18h 30m
American Airlines
Deal found 6/10![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:41 pm
MCI
- GCM
1 stop16h 15m
American Airlines
Fri 12/183:35 pm
GCM
- MCI
1 stop7h 36m
American Airlines
Deal found 6/9![American Airlines logo]()
$589
Best flights from Missouri to Grand CaymanDiscover carefully curated flight deals from Missouri to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
Discover carefully curated flight deals from Missouri to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am
STL
- GCM
1 stop8h 10m
American Airlines
Tue 8/2512:30 pm
GCM
- STL
2 stops11h 44m
American Airlines
Deal found 6/9![American Airlines logo]()
$429
This Air Canada deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:15 pm
STL
- GCM
1 stop19h 45m
Air Canada
Wed 11/41:10 pm
GCM
- STL
1 stop27h 20m
Air Canada
Deal found 6/10![Air Canada logo]()
$509
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
STL
- GCM
1 stop5h 39m
Delta
Tue 8/251:04 pm
GCM
- STL
1 stop10h 17m
Delta
Deal found 6/8![Delta logo]()
$579
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:16 am
MCI
- GCM
1 stop6h 14m
United Airlines
Fri 7/311:35 pm
GCM
- MCI
1 stop8h 56m
United Airlines
Deal found 6/8![United Airlines logo]()
$589
This Justfly.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:15 pm
STL
- GCM
1 stop19h 45m
Air Canada
Fri 11/61:10 pm
GCM
- STL
1 stop27h 20m
Air Canada
Deal found 6/6![Air Canada logo]()
$530
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:10 am
STL
- GCM
1 stop9h 53m
American Airlines
Wed 7/292:41 pm
GCM
- STL
1 stop9h 17m
American Airlines
Deal found 6/10![American Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:30 am
MCI
- GCM
1 stop7h 05m
United Airlines
Sat 8/11:35 pm
GCM
- MCI
2 stops19h 07m
United Airlines
Deal found 6/6![United Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:00 am
MCI
- GCM
1 stop11h 10m
American Airlines
Tue 8/112:10 pm
GCM
- MCI
2 stops18h 30m
American Airlines
Deal found 6/11![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:08 pm
MCI
- GCM
2 stops17h 52m
American Airlines
Sat 8/84:00 pm
GCM
- MCI
2 stops18h 30m
American Airlines
Deal found 6/10![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:13 pm
STL
- GCM
2 stops16h 47m
American Airlines
Wed 7/292:41 pm
GCM
- STL
1 stop9h 17m
American Airlines
Deal found 6/7![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:57 pm
STL
- GCM
2 stops17h 33m
American Airlines
Fri 8/282:10 pm
GCM
- STL
1 stop8h 30m
American Airlines
Deal found 6/11![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:04 pm
MCI
- GCM
2 stops17h 56m
American Airlines
Tue 7/2812:02 pm
GCM
- MCI
2 stops12h 17m
American Airlines
Deal found 6/7![American Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:30 am
MCI
- GCM
1 stop8h 47m
American Airlines
Sat 8/2211:55 am
GCM
- MCI
1 stop12h 04m
American Airlines
Deal found 6/9![American Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:21 pm
MCI
- GCM
1 stop18h 24m
American Airlines
Mon 7/205:10 pm
GCM
- MCI
1 stop6h 49m
American Airlines
Deal found 6/7![American Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:30 am
MCI
- GCM
2 stops10h 40m
American Airlines
Sat 7/114:07 pm
GCM
- MCI
2 stops16h 25m
American Airlines
Deal found 6/6![American Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:00 am
MCI
- GCM
2 stops10h 10m
American Airlines
Fri 8/72:10 pm
GCM
- MCI
2 stops20h 20m
American Airlines
Deal found 6/10![American Airlines logo]()
$594
Last-minute flights from Missouri to Grand CaymanDiscover last-minute flight deals from Missouri to Grand Cayman. Data last updated June 11, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Grand Cayman. Data last updated June 11, 2026 and is based on user searches.
This Air Canada deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:15 pm
STL
- GCM
1 stop21h 10m
Air Canada
Sat 6/2010:55 am
GCM
- STL
1 stop25h 26m
Air Canada
Deal found 6/8![Air Canada logo]()
$432
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:14 am
STL
- GCM
1 stop6h 16m
American Airlines
Tue 6/3012:33 pm
GCM
- STL
1 stop11h 11m
American Airlines
Deal found 6/9![American Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:13 pm
STL
- GCM
2 stops16h 47m
American Airlines
Thu 7/1612:02 pm
GCM
- STL
2 stops11h 50m
American Airlines
Deal found 6/9![American Airlines logo]()
$589
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:48 pm
STL
- GCM
1 stop17h 57m
American Airlines
Wed 7/222:41 pm
GCM
- STL
1 stop9h 17m
American Airlines
Deal found 6/10![American Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:39 am
MCI
- GCM
1 stop6h 57m
American Airlines
Tue 7/2812:33 pm
GCM
- MCI
1 stop10h 25m
American Airlines
Deal found 6/7![American Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:04 pm
MCI
- GCM
2 stops17h 56m
American Airlines
Tue 7/2812:02 pm
GCM
- MCI
2 stops12h 17m
American Airlines
Deal found 6/7![American Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:30 am
MCI
- GCM
1 stop7h 05m
United Airlines
Sat 8/14:45 pm
GCM
- MCI
1 stop17h 18m
United Airlines
Deal found 6/6![United Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:20 pm
MCI
- GCM
2 stops18h 05m
American Airlines
Sat 8/84:00 pm
GCM
- MCI
2 stops18h 30m
American Airlines
Deal found 6/8![American Airlines logo]()
$603
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:48 pm
STL
- GCM
2 stops17h 12m
American Airlines
Wed 7/2912:02 pm
GCM
- STL
1 stop10h 52m
American Airlines
Deal found 6/9![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:00 am
MCI
- GCM
1 stop6h 00m
American Airlines
Thu 7/305:10 pm
GCM
- MCI
1 stop6h 49m
American Airlines
Deal found 6/9![American Airlines logo]()
$598
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:00 am
MCI
- GCM
1 stop11h 10m
American Airlines
Tue 8/112:10 pm
GCM
- MCI
2 stops18h 30m
American Airlines
Deal found 6/10![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:00 am
MCI
- GCM
2 stops10h 10m
American Airlines
Fri 8/72:10 pm
GCM
- MCI
2 stops20h 20m
American Airlines
Deal found 6/10![American Airlines logo]()
$594
One-way flights from Missouri to Grand CaymanSearch for one-way flight options from Missouri to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
Search for one-way flight options from Missouri to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:10 am
MCI
- GCM
1 stop9h 20m
United Airlines
Deal found 6/10![United Airlines logo]()
$157
This Expedia deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:10 pm
STL
- GCM
2 stops47h 20m
Air Canada
Deal found 6/6![Air Canada logo]()
$159
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:36 pm
MCI
- GCM
2 stops16h 22m
American Airlines
Deal found 6/10![American Airlines logo]()
$163
This Travelocity deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:55 am
STL
- GCM
1 stop26h 35m
Air Canada
Deal found 6/6![Air Canada logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:11 pm
MCI
- GCM
2 stops21h 54m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$233
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:40 am
MCI
- GCM
1 stop6h 00m
Delta
Deal found 6/7![Delta logo]()
$237
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:08 pm
STL
- GCM
1 stop18h 27m
American Airlines
Deal found 6/6![American Airlines logo]()
$264
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:15 pm
STL
- GCM
1 stop19h 45m
Air Canada
Deal found 6/10![Air Canada logo]()
$296
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:16 am
MCI
- GCM
1 stop6h 14m
United Airlines
Deal found 6/9![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:00 am
STL
- GCM
2 stops10h 11m
American Airlines
Deal found 6/10![American Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:29 am
STL
- GCM
2 stops9h 38m
American Airlines
Deal found 6/10![American Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:10 pm
STL
- GCM
3 stops25h 05m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$380
Find flight deals from Missouri to Grand Cayman
Keep the following information in mind while searching for Missouri to Grand Cayman flight deals. Data was last updated June 11, 2026.
Round-trip from | $419 (American Airlines) |
|---|---|
One-way from | $157 (United Airlines) |
Popular in | May |
Cheapest in | September |
Average price | $662 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from Missouri to Grand Cayman that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 8/19
5:00 am-1:10 pm
1 stop8h 10m
George Town Owen Roberts Intl
Tue 8/25
12:30 pm-12:14 am
2 stops11h 44m
$429
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 10/31
4:15 pm-12:00 pm
1 stop19h 45m
George Town Owen Roberts Intl
Wed 11/4
1:10 pm-3:30 pm
1 stop27h 20m
$509
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 10/31
4:15 pm-12:00 pm
1 stop19h 45m
George Town Owen Roberts Intl
Fri 11/6
1:10 pm-3:30 pm
1 stop27h 20m
$530
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Wed 8/19
6:00 am-11:39 am
1 stop5h 39m
George Town Owen Roberts Intl
Tue 8/25
1:04 pm-11:21 pm
1 stop10h 17m
$579
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sat 7/25
5:10 am-3:03 pm
1 stop9h 53m
George Town Owen Roberts Intl
Wed 7/29
2:41 pm-11:58 pm
1 stop9h 17m
$579
Kansas CityGeorge Town
MCI - GCM
MCIGCM
Kansas City
Tue 7/28
5:00 am-4:10 pm
1 stop11h 10m
George Town Owen Roberts Intl
Tue 8/11
2:10 pm-8:40 am
2 stops18h 30m
$584
Kansas CityGeorge Town
MCI - GCM
MCIGCM
Kansas City
Sat 7/25
5:08 pm-11:00 am
2 stops17h 52m
George Town Owen Roberts Intl
Sat 8/8
4:00 pm-10:30 am
2 stops18h 30m
$584
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Sun 7/26
6:13 pm-11:00 am
2 stops16h 47m
George Town Owen Roberts Intl
Wed 7/29
2:41 pm-11:58 pm
1 stop9h 17m
$584
St. LouisGeorge Town
STL - GCM
STLGCM
Lambert-St Louis
Fri 8/21
5:57 pm-11:30 am
2 stops17h 33m
George Town Owen Roberts Intl
Fri 8/28
2:10 pm-10:40 pm
1 stop8h 30m
$584
Quickest round-trip
Kansas CityGeorge Town
MCI - GCM
MCIGCM
Kansas City
Fri 7/24
6:16 am-12:30 pm
1 stop6h 14m
George Town Owen Roberts Intl
Fri 7/31
1:35 pm-10:31 pm
1 stop8h 56m
$589
Showing 1-10 of 29 resultsSorted by cheapest first
Best time to book a flight from Missouri to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Missouri with our price prediction graph.
STL-GCM
MCI-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Grand Cayman
USMO-zzLAW
STL-GCM
MCI-GCM
What is the cheapest month to book a flight from Missouri to Grand Cayman?
Currently, February is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $108). Flying from Missouri to Grand Cayman in October is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Grand Cayman
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Complete your trip
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Search flights from Missouri to Grand Cayman by cabin class
Find flights from Missouri to Grand Cayman, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Grand Cayman flights
Browse other Missouri and Grand Cayman flight options. Last updated on June 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Missouri to Grand Cayman
Discover the top 4 airlines that operate flights from Missouri to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$190 | Average$534 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$364 | Average$641 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$429 | Average$578 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$458 | Average$624 | FlexibilityNo cancel fee | On-time71% |