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Grand Cayman

$340+ Cheap flights from Knoxville (TYS) to Grand Cayman

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GCM
jan 20 — jan 271
tis 1/20
tis 1/27
1 adult, Economy
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Cheap flight deals from Knoxville to Grand Cayman

Cheapest flights from Knoxville to Grand Cayman
Explore the most affordable flight options available from Knoxville to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on december 21, 2025.

This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lör 12/277:29 pmTYS - GCM
1 stop18h 52mAmerican Airlines
lör 1/37:30 amGCM - TYS
1 stop10h 53mAmerican Airlines
Deal found 12/19$990

Find flight deals from Knoxville to Grand Cayman

Keep the following information in mind while searching for Knoxville to Grand Cayman flight deals. Data was last updated december 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$340
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$581
Provider with most accurate pricing for Knoxville McGhee Tyson-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-George Town Owen Roberts Intl flights.
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From Knoxville McGhee Tyson to Grand Cayman
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($85 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated december 21, 2025.
Use the filters below to find and compare flights from Knoxville to Grand Cayman that are best for you.

Fly from

Knoxville

Fly to

Grand Cayman

Route

Depart

Return

Price

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

lör 1/31

5:59 pm-1:53 pm

1 stop19h 54m

George Town Owen Roberts Intl

lör 2/7

2:34 pm-8:39 am

1 stop18h 05m

$340

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

tis 2/3

6:05 am-11:26 am

1 stop5h 21m

George Town Owen Roberts Intl

tis 2/10

8:50 am-10:54 pm

2 stops14h 04m

$538

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

lör 3/28

7:39 pm-1:25 pm

1 stop18h 46m

George Town Owen Roberts Intl

lör 4/4

7:45 am-7:09 pm

1 stop10h 24m

$587

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

tors 1/22

5:40 am-12:40 pm

1 stop7h 00m

George Town Owen Roberts Intl

mån 1/26

2:05 pm-9:24 pm

1 stop7h 19m

$600

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

tors 1/22

8:09 am-8:20 pm

2 stops12h 11m

George Town Owen Roberts Intl

mån 1/26

12:50 pm-9:44 pm

2 stops8h 54m

$605

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

tors 2/12

6:02 am-8:15 pm

1 stop14h 13m

George Town Owen Roberts Intl

mån 2/16

8:45 am-11:55 pm

1 stop15h 10m

$615

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

Best time to book a flight from Knoxville to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Grand Cayman
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated december 21, 2025.
Get a feel of what it's like to fly with American Airlines from Knoxville to Grand Cayman by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Overall

7.2

Food

6.5

Entertainment

6.9

Comfort

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Overall

7.2

Food

6.5

Entertainment

6.9

Comfort

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Grand Cayman?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Grand Cayman. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Grand Cayman?

    Airlines like American Airlines fly from Knoxville to Grand Cayman in about 5h 21m. The time it takes to get you to your destination can typically vary by up to . There are 1151 mi between Knoxville and Grand Cayman.

  • Can I find deals for flights from Knoxville to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Knoxville to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Grand Cayman.

  • Can I find deals for business class flights from Knoxville to Grand Cayman?

    Yes. Cheapflights offers flight deals from Knoxville to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Knoxville to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to George Town flights
Knoxville to George Town flights
Memphis to George Town flights
Blountville to George Town flights

Top airline flying from Knoxville to Grand Cayman

Discover the top airline that operate flights from Knoxville to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated december 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$503Average$666FlexibilityNo cancel feeOn-time71%

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