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Grand Cayman

$255+ Cheap flights from Knoxville (TYS) to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GCM
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Knoxville to Grand Cayman

Keep the following information in mind while searching for Knoxville to Grand Cayman flight deals. Data was last updated September 15, 2025.

Round-trip from

$526
(Mytrip)

One-way from

$255
(Kiwi.com)

Popular in

March

Cheapest in

January

Average price

$634
From Knoxville McGhee Tyson to Grand Cayman
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One-way flight from Knoxville McGhee Tyson to Grand Cayman
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to Grand Cayman

Cheapest flights from Knoxville to Grand Cayman
Explore the most affordable flight options available from Knoxville to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:58 amTYS - GCM
3 stops26h 27mMultiple Airlines
Thu 11/61:30 pmGCM - TYS
2 stops32h 56mMultiple Airlines
Deal found 9/14$526
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:15 amTYS - GCM
1 stop7h 55mAmerican Airlines
Thu 11/63:10 pmGCM - TYS
1 stop7h 44mAmerican Airlines
Deal found 9/14$558
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:11 pmTYS - GCM
1 stop18h 14mAmerican Airlines
Sat 10/183:15 pmGCM - TYS
2 stops17h 17mAmerican Airlines
Deal found 9/13$586
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:45 pmTYS - GCM
2 stops16h 25mAmerican Airlines
Wed 10/88:25 amGCM - TYS
1 stop14h 14mAmerican Airlines
Deal found 9/13$589
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:53 pmTYS - GCM
1 stop19h 57mAmerican Airlines
Sat 1/37:30 amGCM - TYS
1 stop10h 53mAmerican Airlines
Deal found 9/14$939
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:30 amTYS - GCM
1 stop5h 52mAmerican Airlines
Sat 9/2012:25 pmGCM - TYS
1 stop5h 40mAmerican Airlines
Deal found 9/14$950
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:00 amTYS - GCM
1 stop6h 45mUnited Airlines
Sat 12/65:30 pmGCM - TYS
1 stop25h 59mUnited Airlines
Deal found 9/13$962

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Knoxville to Grand Cayman that are best for you.

Fly from

Knoxville

Fly to

Grand Cayman

Route

Depart

Return

Price

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Thu 10/30

9:58 am-11:25 am

2 stops26h 27m

George Town Owen Roberts Intl

Thu 11/6

1:30 pm-10:26 pm

2 stops32h 56m

$526

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Tue 3/10

7:07 am-11:35 am

1 stop5h 28m

George Town Owen Roberts Intl

Wed 3/11

1:00 pm-9:43 pm

1 stop7h 43m

$550

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Thu 10/30

6:15 am-1:10 pm

1 stop7h 55m

George Town Owen Roberts Intl

Thu 11/6

3:10 pm-10:54 pm

1 stop7h 44m

$558

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Sat 10/11

6:11 pm-11:25 am

1 stop18h 14m

George Town Owen Roberts Intl

Sat 10/18

3:15 pm-9:32 am

2 stops17h 17m

$586

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Sat 10/4

7:45 pm-11:10 am

2 stops16h 25m

George Town Owen Roberts Intl

Wed 10/8

8:25 am-11:39 pm

1 stop14h 14m

$589

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Fri 10/10

7:02 pm-11:35 am

3 stops41h 33m

$255

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Fri 10/10

5:44 am-11:35 am

1 stop6h 51m

$301

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Knoxville to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Grand Cayman
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated September 15, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Knoxville to Grand Cayman by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Grand Cayman?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Grand Cayman. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Grand Cayman?

    Airlines like Delta fly from Knoxville to Grand Cayman in about 5h 28m. The time it takes to get you to your destination can typically vary by up to . There are 1151 mi between Knoxville and Grand Cayman.

  • Can I find deals for flights from Knoxville to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Knoxville to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Grand Cayman.

  • Can I find deals for business class flights from Knoxville to Grand Cayman?

    Yes. Cheapflights offers flight deals from Knoxville to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Grand Cayman (average of $467). Flying from Knoxville to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to George Town flights
Knoxville to George Town flights
Memphis to George Town flights
Blountville to George Town flights

Top 2 airlines flying from Knoxville to Grand Cayman

Discover the top 2 airlines that operate flights from Knoxville to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$469Average$529FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$519Average$684FlexibilityNo cancel feeOn-time71%

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