Frankfurt am Main

$379+ Cheap flights from Panama City, FL (ECP) to Frankfurt am Main

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — FRA
Oct 16 — Oct 231
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Frankfurt am Main with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Frankfurt am Main

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Frankfurt am Main (FK0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$558
(KLM)

One-way from

$379
(Delta)

Popular in

July

Cheapest in

March

Average price

$986
From Panama City NW Florida Beaches to Frankfurt am Main
One-way flight from Panama City NW Florida Beaches to Frankfurt am Main
Highest demand for flights based on searches. 8% potential increase in price ($107 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($51 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Panama City to Frankfurt am Main

Cheapest flights from Panama City to Frankfurt am Main
Explore the most affordable flight options available from Panama City to Frankfurt am Main. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This KLM deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/139:29 amECP - FRA
1 stop16h 26mKLM
Tue 12/169:50 amFRA - ECP
1 stop19h 48mKLM
Deal found 9/14$558
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:00 amECP - FRA
1 stop19h 55mDelta
Tue 12/167:05 amFRA - ECP
2 stops22h 33mDelta
Deal found 9/14$578
This Flighttix deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:00 pmECP - FRA
2 stops20h 45mScandinavian Airlines
Thu 11/63:15 pmFRA - ECP
2 stops38h 55mScandinavian Airlines
Deal found 9/15$591
This Flighttix deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:00 pmECP - FRA
2 stops32h 50mVirgin Atlantic
Thu 11/69:50 amFRA - ECP
1 stop20h 20mVirgin Atlantic
Deal found 9/15$625
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/262:05 pmECP - FRA
2 stops14h 20mDelta
Wed 10/810:40 amFRA - ECP
1 stop12h 47mDelta
Deal found 9/15$746
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:32 amECP - FRA
1 stop19h 13mAmerican Airlines
Wed 10/89:20 amFRA - ECP
1 stop20h 33mAmerican Airlines
Deal found 9/15$977
This Scandinavian Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/262:05 pmECP - FRA
3 stops20h 40mScandinavian Airlines
Wed 10/87:00 amFRA - ECP
3 stops23h 10mScandinavian Airlines
Deal found 9/15$3,189

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Frankfurt am Main that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Panama City to Frankfurt am Main that are best for you.

Fly from

Panama City

Fly to

Frankfurt am Main

Route

Depart

Return

Price

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Mon 10/13

9:29 am-8:55 am

1 stop16h 26m

Frankfurt am Main

Tue 12/16

9:50 am-10:38 pm

1 stop19h 48m

$558

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Mon 10/13

6:00 am-8:55 am

1 stop19h 55m

Frankfurt am Main

Tue 12/16

7:05 am-10:38 pm

2 stops22h 33m

$578

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Thu 10/30

5:00 pm-7:50 am

2 stops32h 50m

Frankfurt am Main

Thu 11/6

9:50 am-11:10 pm

1 stop20h 20m

$625

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Fri 9/26

2:05 pm-11:25 am

2 stops14h 20m

Frankfurt am Main

Wed 10/8

10:40 am-4:27 pm

1 stop12h 47m

$746

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Thu 10/30

1:25 pm-7:45 pm

2 stops24h 20m

Frankfurt am Main

Thu 11/6

6:55 am-11:10 pm

3 stops23h 15m

$901

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Fri 9/26

6:32 am-8:45 am

1 stop19h 13m

Frankfurt am Main

Wed 10/8

9:20 am-10:53 pm

1 stop20h 33m

$977

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Fri 9/26

2:05 pm-5:45 pm

3 stops20h 40m

Frankfurt am Main

Wed 10/8

7:00 am-11:10 pm

3 stops23h 10m

$3,189

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Wed 11/19

9:20 am-8:40 am

1 stop16h 20m

Frankfurt am Main

Wed 12/17

7:05 am-10:38 pm

2 stops22h 33m

$3,561

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Tue 11/25

6:00 am-8:40 am

1 stop19h 40m

$379

Panama CityFrankfurt am Main

ECP - FRA

ECPFRA

Panama City NW Florida Beaches

Mon 11/24

6:00 am-8:40 am

1 stop19h 40m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 11 results
1
2

Best time to book a flight from Panama City to Frankfurt am Main

Have a flexible travel schedule? Discover the best time to fly to Frankfurt am Main from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Frankfurt am Main

What is the cheapest month to book a flight from Panama City, Florida to Frankfurt am Main?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Frankfurt am Main (average of $729). Flying from Panama City, Florida to Frankfurt am Main in June is currently the most expensive (average of $1,091). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to FRA?

Find hourly flight availability from Panama City to Frankfurt am Main. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 22% on flights from Panama City, Florida to Frankfurt am Main by exploring options for tickets in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Frankfurt am Main. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Panama City to Frankfurt am Main?

    If you book a flight to Frankfurt am Main from Panama City, you will be flying from NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City. There are 0 flights from NW Florida Beaches to Frankfurt am Main per day from 0 different airlines.

  • How long is the flight from Panama City, Florida to Frankfurt am Main?

    KLM, Delta, and Virgin Atlantic can get you from Panama City, Florida to Frankfurt am Main in just under 16h 26m. Your travel time can differ by up to 16h 24m. The distance from Panama City, Florida to Frankfurt am Main is about 4819 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama City to Frankfurt am Main that include hotel bookings?

    Yes. In addition to deals on Panama City to Frankfurt am Main flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Frankfurt am Main?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Frankfurt am Main.

  • Can I find deals for business class flights from Panama City to Frankfurt am Main?

    Yes. Cheapflights offers flight deals from Panama City to Frankfurt am Main by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Frankfurt am Main?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Frankfurt am Main (average of $729). Flying from Panama City, Florida to Frankfurt am Main in June is currently the most expensive (average of $1,091). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Frankfurt am Main

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.