$210+ Cheap flights from Santo Domingo (SDQ) to Chile
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SCL
May 1 — May 81
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Santo Domingo to ChileExplore the most affordable flight options available from Santo Domingo to Chile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.
Explore the most affordable flight options available from Santo Domingo to Chile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.
This Arajet deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:45 pm
SDQ
- SCL
1 stop12h 50m
Multiple Airlines
Mon 10/196:00 am
SCL
- SDQ
1 stop11h 55m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$441
This Arajet deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:45 pm
SDQ
- SCL
1 stop12h 50m
Multiple Airlines
Mon 10/196:00 am
SCL
- SDQ
1 stop11h 55m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$519
This Arajet deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:55 am
SDQ
- SCL
1 stop14h 00m
Multiple Airlines
Mon 6/85:00 am
SCL
- SDQ
1 stop11h 55m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$525
This Arajet deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:45 pm
SDQ
- SCL
1 stop12h 50m
Multiple Airlines
Thu 9/33:35 am
SCL
- SDQ
1 stop12h 10m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$531
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:00 pm
SDQ
- SCL
1 stop22h 46m
Multiple Airlines
Mon 6/85:00 am
SCL
- SDQ
1 stop11h 55m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$558
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:00 pm
SDQ
- SCL
1 stop17h 26m
Multiple Airlines
Mon 6/155:00 am
SCL
- SDQ
1 stop11h 55m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$560
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:13 pm
SDQ
- SCL
1 stop29h 23m
Multiple Airlines
Mon 5/185:00 am
SCL
- SDQ
1 stop11h 55m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:00 pm
SDQ
- SCL
1 stop31h 16m
Multiple Airlines
Thu 5/216:40 am
SCL
- SDQ
1 stop11h 15m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$583
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:00 pm
SDQ
- SCL
1 stop22h 46m
Multiple Airlines
Tue 6/94:41 am
SCL
- SDQ
1 stop28h 04m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$592
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:00 pm
SDQ
- SCL
1 stop22h 46m
Multiple Airlines
Tue 5/54:46 am
SCL
- SDQ
1 stop27h 59m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$602
Best flights from Santo Domingo to ChileDiscover carefully curated flight deals from Santo Domingo to Chile that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2026.
Discover carefully curated flight deals from Santo Domingo to Chile that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2026.
This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:40 pm
SDQ
- SCL
1 stop14h 20m
Copa Airlines
Sun 6/74:09 am
SCL
- SDQ
1 stop18h 47m
Copa Airlines
Deal found 3/30![Copa Airlines logo]()
$800
This FlightHub deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:50 pm
SDQ
- SCL
1 stop9h 55m
Multiple Airlines
Wed 5/1312:30 am
SCL
- SDQ
2 stops12h 43m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$1,454
This Copa Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/612:13 pm
SDQ
- SCL
1 stop13h 37m
Copa Airlines
Sun 7/194:14 am
SCL
- SDQ
1 stop12h 01m
Copa Airlines
Deal found 3/29![Copa Airlines logo]()
$823
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:05 am
SDQ
- SCL
2 stops25h 10m
Delta
Sun 5/1010:30 am
SCL
- SDQ
2 stops26h 54m
Delta
Deal found 3/28![Delta logo]()
$2,753
This British Airways deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:00 am
SDQ
- SCL
2 stops48h 45m
British Airways
Tue 6/233:00 pm
SCL
- SDQ
2 stops42h 24m
British Airways
Deal found 3/31![British Airways logo]()
$3,032
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:05 am
SDQ
- SCL
2 stops25h 10m
Delta
Tue 6/910:30 am
SCL
- SDQ
2 stops26h 46m
Delta
Deal found 3/30![Delta logo]()
$2,785
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
SDQ
- SCL
2 stops25h 15m
Delta
Tue 8/2510:30 am
SCL
- SDQ
2 stops26h 42m
Delta
Deal found 3/29![Delta logo]()
$2,785
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:48 pm
SDQ
- SCL
1 stop16h 27m
Delta
Sun 6/78:40 pm
SCL
- SDQ
2 stops28h 02m
Delta
Deal found 3/29![Delta logo]()
$2,832
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:05 am
SDQ
- SCL
2 stops25h 10m
Delta
Sun 4/2610:30 am
SCL
- SDQ
2 stops26h 42m
Delta
Deal found 3/28![Delta logo]()
$2,986
Last-minute flights from Santo Domingo to ChileDiscover last-minute flight deals from Santo Domingo to Chile. Data last updated April 1, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to Chile. Data last updated April 1, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:45 pm
SDQ
- SCL
1 stop16h 00m
Avianca
Thu 4/166:40 am
SCL
- SDQ
1 stop11h 15m
Avianca
Deal found 3/29![Avianca logo]()
$673
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:00 pm
SDQ
- SCL
1 stop22h 46m
Multiple Airlines
Tue 5/54:46 am
SCL
- SDQ
1 stop27h 59m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$602
This Mytrip deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:45 pm
SDQ
- SCL
2 stops24h 45m
Multiple Airlines
Wed 5/136:40 am
SCL
- SDQ
1 stop11h 15m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$666
This Mytrip deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:20 am
SDQ
- SCL
3 stops44h 57m
Multiple Airlines
Thu 5/143:20 pm
SCL
- SDQ
1 stop26h 35m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$647
This FlightHub deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:45 pm
SDQ
- SCL
1 stop10h 35m
Avianca
Thu 5/146:40 am
SCL
- SDQ
1 stop11h 15m
Avianca
Deal found 3/28![Avianca logo]()
$670
This Trip.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:00 pm
SDQ
- SCL
1 stop16h 30m
Multiple Airlines
Thu 5/146:40 am
SCL
- SDQ
1 stop11h 15m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$626
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:13 pm
SDQ
- SCL
1 stop29h 23m
Multiple Airlines
Mon 5/185:00 am
SCL
- SDQ
1 stop11h 55m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:00 pm
SDQ
- SCL
1 stop31h 16m
Multiple Airlines
Thu 5/216:40 am
SCL
- SDQ
1 stop11h 15m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$583
This Arajet deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:55 am
SDQ
- SCL
1 stop14h 00m
Multiple Airlines
Mon 6/85:00 am
SCL
- SDQ
1 stop11h 55m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$525
One-way flights from Santo Domingo to ChileSearch for one-way flight options from Santo Domingo to Chile. Find affordable one-way fares based on user searches. Data last updated April 1, 2026.
Search for one-way flight options from Santo Domingo to Chile. Find affordable one-way fares based on user searches. Data last updated April 1, 2026.
This Arajet deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:45 pm
SDQ
- SCL
1 stop12h 50m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$210
This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:12 pm
SDQ
- SCL
1 stop14h 44m
Copa Airlines
Deal found 3/30![Copa Airlines logo]()
$393
This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:53 am
SDQ
- SCL
1 stop10h 30m
Copa Airlines
Deal found 3/30![Copa Airlines logo]()
$404
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:04 am
SDQ
- SCL
1 stop17h 22m
Copa Airlines
Deal found 3/31![Copa Airlines logo]()
$405
This Arajet deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:55 am
SDQ
- SCL
1 stop14h 00m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$406
This FlightHub deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:39 pm
SDQ
- SCL
2 stops19h 36m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$896
Find flight deals from Santo Domingo to Chile
Keep the following information in mind while searching for Santo Domingo to Chile flight deals. Data was last updated April 1, 2026.
Round-trip from | $525 (Arajet) |
|---|---|
One-way from | $210 (Arajet) |
Popular in | January |
Cheapest in | October |
Average price | $580 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Santo Domingo to Chile that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Mon 6/1
12:40 pm-3:00 am
1 stop14h 20m
Santiago Arturo Merino Benitez
Sun 6/7
4:09 am-10:56 pm
1 stop18h 47m
$800
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Mon 7/6
12:13 pm-1:50 am
1 stop13h 37m
Santiago Arturo Merino Benitez
Sun 7/19
4:14 am-4:15 pm
1 stop12h 01m
$823
Quickest round-trip
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Sat 5/9
6:50 pm-4:45 am
1 stop9h 55m
Santiago Arturo Merino Benitez
Wed 5/13
12:30 am-1:13 pm
2 stops12h 43m
$1,454
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Thu 4/30
6:05 am-7:15 am
2 stops25h 10m
Santiago Arturo Merino Benitez
Sun 5/10
10:30 am-1:24 pm
2 stops26h 54m
$2,753
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Wed 6/3
6:05 am-7:15 am
2 stops25h 10m
Santiago Arturo Merino Benitez
Tue 6/9
10:30 am-1:16 pm
2 stops26h 46m
$2,785
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Thu 8/20
6:00 am-7:15 am
2 stops25h 15m
Santiago Arturo Merino Benitez
Tue 8/25
10:30 am-1:12 pm
2 stops26h 42m
$2,785
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Mon 6/1
2:48 pm-7:15 am
1 stop16h 27m
Santiago Arturo Merino Benitez
Sun 6/7
8:40 pm-12:42 am
2 stops28h 02m
$2,832
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Sun 4/19
6:05 am-7:15 am
2 stops25h 10m
Santiago Arturo Merino Benitez
Sun 4/26
10:30 am-1:12 pm
2 stops26h 42m
$2,986
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Fri 6/19
7:00 am-7:45 am
2 stops48h 45m
Santiago Arturo Merino Benitez
Tue 6/23
3:00 pm-9:24 am
2 stops42h 24m
$3,032
Cheapest one-way
Santo DomingoSantiago
SDQ - SCL
SDQSCL
Santo Domingo Las Americas
Thu 4/16
1:45 pm-2:35 am
1 stop12h 50m
$210
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Santo Domingo to Chile
Have a flexible travel schedule? Discover the best time to fly to Chile from Santo Domingo with our price prediction graph.
SDQ-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santo Domingo to Chile
SDQ-CL0
SDQ-SCL
What is the cheapest month to book a flight from Santo Domingo to Chile?
Currently, September is the cheapest month in which you can book a flight from Santo Domingo to Chile (average of $237). Flying from Santo Domingo to Chile in January is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Chile
Get insights into the airlines that provide service to Chile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chile. Reviews last updated April 1, 2026.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Santo Domingo to Chile by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Food
6.8
Comfort
7.4
Crew
8.1
Entertainment
6.8
Overall
7.5
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Food
6.8
Comfort
7.4
Crew
8.1
Entertainment
6.8
Overall
7.5
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Food
6.8
Comfort
7.4
Crew
8.1
Entertainment
6.8
Overall
7.5
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to Chile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Santo Domingo to Chile
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Chile by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Santo Domingo to Chile, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Santo Domingo and Chile flights
Browse other Santo Domingo and Chile flight options. Last updated on April 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Chile regions
Consider these flights traveling to Chile regions.
Top 2 airlines flying from Santo Domingo to Chile
Discover the top 2 airlines that operate flights from Santo Domingo to Chile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$281 | Average$772 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$465 | Average$611 | FlexibilityNo cancel fee | On-time71% |