$328+ Cheap flights from Missouri to Brussels
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BRU
Mar 10 — Mar 171
1 adult, Economy
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Cheapest flights from Missouri to BrusselsExplore the most affordable flight options available from Missouri to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.
Explore the most affordable flight options available from Missouri to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:25 am
STL
- BRU
2 stops19h 50m
United Airlines
Tue 3/2410:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/6![United Airlines logo]()
$486
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:05 pm
STL
- BRU
2 stops15h 10m
United Airlines
Wed 3/2510:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/5![United Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:19 pm
JLN
- BRU
2 stops35h 56m
United Airlines
Sun 3/810:10 am
BRU
- JLN
1 stop13h 33m
United Airlines
Deal found 2/4![United Airlines logo]()
$501
This Cheapflightsfares deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:28 am
STL
- BRU
2 stops19h 42m
Lufthansa
Wed 3/2512:45 pm
BRU
- STL
2 stops16h 14m
Lufthansa
Deal found 2/7![Lufthansa logo]()
$505
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:54 am
MCI
- BRU
1 stop20h 06m
Delta
Thu 3/2610:00 am
BRU
- MCI
1 stop18h 04m
Delta
Deal found 2/6![Delta logo]()
$509
This oojo deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:30 pm
STL
- BRU
2 stops19h 40m
British Airways
Fri 5/810:45 am
BRU
- STL
2 stops20h 11m
British Airways
Deal found 2/5![British Airways logo]()
$510
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:04 pm
STL
- BRU
1 stop13h 56m
Delta
Wed 3/252:45 pm
BRU
- STL
2 stops24h 20m
Delta
Deal found 2/7![Delta logo]()
$519
This Finnair deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:30 am
MCI
- BRU
2 stops34h 05m
Multiple Airlines
Mon 5/117:05 pm
BRU
- MCI
2 stops31h 16m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:45 am
STL
- BRU
1 stop18h 15m
United Airlines
Fri 4/179:25 am
BRU
- STL
2 stops33h 57m
United Airlines
Deal found 2/5![United Airlines logo]()
$538
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:22 pm
MCI
- BRU
1 stop10h 38m
United Airlines
Mon 5/119:25 am
BRU
- MCI
2 stops36h 01m
United Airlines
Deal found 2/5![United Airlines logo]()
$538
This KAYAK deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:00 am
STL
- BRU
1 stop16h 00m
Multiple Airlines
Fri 5/89:25 am
BRU
- STL
1 stop17h 40m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:08 pm
SGF
- BRU
2 stops37h 07m
United Airlines
Mon 3/309:55 am
BRU
- SGF
2 stops38h 29m
United Airlines
Deal found 2/5![United Airlines logo]()
$562
Best flights from Missouri to BrusselsDiscover carefully curated flight deals from Missouri to Brussels that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 8, 2026.
Discover carefully curated flight deals from Missouri to Brussels that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 8, 2026.
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:25 am
STL
- BRU
2 stops19h 50m
United Airlines
Tue 3/2410:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/6![United Airlines logo]()
$486
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:54 am
MCI
- BRU
1 stop20h 06m
Delta
Thu 3/2610:00 am
BRU
- MCI
1 stop15h 56m
Delta
Deal found 2/4![Delta logo]()
$509
This oojo deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:30 pm
STL
- BRU
2 stops19h 40m
British Airways
Fri 5/810:45 am
BRU
- STL
2 stops20h 11m
British Airways
Deal found 2/5![British Airways logo]()
$510
This Cheapflightsfares deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:50 pm
STL
- BRU
1 stop11h 20m
Lufthansa
Wed 3/2512:45 pm
BRU
- STL
2 stops16h 14m
Lufthansa
Deal found 2/6![Lufthansa logo]()
$513
This KAYAK deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:00 am
STL
- BRU
1 stop16h 00m
Multiple Airlines
Fri 5/89:25 am
BRU
- STL
1 stop17h 40m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$551
This KLM deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:48 am
SGF
- BRU
1 stop14h 12m
KLM
Mon 3/309:45 am
BRU
- SGF
1 stop15h 26m
KLM
Deal found 2/5![KLM logo]()
$595
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:05 pm
STL
- BRU
2 stops15h 10m
United Airlines
Wed 3/2510:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/5![United Airlines logo]()
$490
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:04 pm
STL
- BRU
1 stop13h 56m
Delta
Wed 3/252:45 pm
BRU
- STL
2 stops24h 20m
Delta
Deal found 2/7![Delta logo]()
$519
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:19 pm
JLN
- BRU
2 stops35h 56m
United Airlines
Sun 3/810:10 am
BRU
- JLN
1 stop13h 33m
United Airlines
Deal found 2/4![United Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:45 am
STL
- BRU
1 stop18h 15m
United Airlines
Fri 4/179:25 am
BRU
- STL
2 stops33h 57m
United Airlines
Deal found 2/5![United Airlines logo]()
$538
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:22 pm
MCI
- BRU
1 stop10h 38m
United Airlines
Mon 5/119:25 am
BRU
- MCI
2 stops36h 01m
United Airlines
Deal found 2/5![United Airlines logo]()
$538
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:08 pm
SGF
- BRU
2 stops37h 07m
United Airlines
Mon 3/309:55 am
BRU
- SGF
2 stops38h 29m
United Airlines
Deal found 2/5![United Airlines logo]()
$562
This Mytrip deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:50 pm
STL
- CRL
2 stops24h 00m
Multiple Airlines
Tue 3/3112:25 pm
CRL
- STL
2 stops32h 00m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$870
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:22 pm
MCI
- BRU
2 stops14h 53m
United Airlines
Sun 3/110:00 am
BRU
- MCI
2 stops42h 59m
United Airlines
Deal found 2/4![United Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:32 am
MCI
- BRU
2 stops18h 43m
United Airlines
Fri 3/610:00 am
BRU
- MCI
2 stops35h 26m
United Airlines
Deal found 2/5![United Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/183:15 pm
SGF
- BRU
2 stops15h 00m
United Airlines
Sun 2/2210:10 am
BRU
- SGF
1 stop18h 49m
United Airlines
Deal found 2/4![United Airlines logo]()
$687
This Mytrip deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:30 am
STL
- CRL
3 stops31h 30m
Multiple Airlines
Mon 6/87:55 pm
CRL
- STL
2 stops24h 30m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$1,540
This Mytrip deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/212:10 pm
STL
- CRL
2 stops16h 20m
Multiple Airlines
Wed 7/159:30 am
CRL
- STL
3 stops35h 32m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$1,608
This Mytrip deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:05 pm
STL
- CRL
3 stops21h 30m
Multiple Airlines
Fri 5/88:45 am
CRL
- STL
3 stops20h 29m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$1,675
Last-minute flights from Missouri to BrusselsDiscover last-minute flight deals from Missouri to Brussels. Data last updated February 8, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Brussels. Data last updated February 8, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:19 pm
JLN
- BRU
2 stops35h 56m
United Airlines
Sun 3/810:10 am
BRU
- JLN
1 stop13h 33m
United Airlines
Deal found 2/4![United Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:25 am
STL
- BRU
1 stop14h 30m
United Airlines
Fri 3/137:00 am
BRU
- STL
1 stop13h 55m
United Airlines
Deal found 2/5![United Airlines logo]()
$656
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:25 am
STL
- BRU
2 stops19h 50m
United Airlines
Tue 3/2410:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/6![United Airlines logo]()
$486
This KLM deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:21 pm
STL
- BRU
1 stop32h 39m
KLM
Tue 3/2410:00 am
BRU
- STL
1 stop29h 05m
KLM
Deal found 2/6![KLM logo]()
$621
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:05 pm
STL
- BRU
2 stops15h 10m
United Airlines
Wed 3/2510:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/5![United Airlines logo]()
$490
This Cheapflightsfares deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:28 am
STL
- BRU
2 stops19h 42m
Lufthansa
Wed 3/2512:45 pm
BRU
- STL
2 stops16h 14m
Lufthansa
Deal found 2/7![Lufthansa logo]()
$505
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:04 pm
STL
- BRU
1 stop13h 56m
Delta
Wed 3/252:45 pm
BRU
- STL
2 stops24h 20m
Delta
Deal found 2/7![Delta logo]()
$519
This KAYAK deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:28 am
STL
- BRU
1 stop14h 37m
Austrian Airlines
Wed 3/2510:10 am
BRU
- STL
1 stop13h 50m
Austrian Airlines
Deal found 2/6![Austrian Airlines logo]()
$658
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:54 am
MCI
- BRU
1 stop20h 06m
Delta
Thu 3/2610:00 am
BRU
- MCI
1 stop18h 04m
Delta
Deal found 2/6![Delta logo]()
$509
This Expedia deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:58 pm
MCI
- BRU
2 stops14h 52m
British Airways
Thu 3/2610:15 am
BRU
- MCI
2 stops18h 13m
British Airways
Deal found 2/4![British Airways logo]()
$649
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:08 pm
SGF
- BRU
2 stops37h 07m
United Airlines
Mon 3/309:55 am
BRU
- SGF
2 stops38h 29m
United Airlines
Deal found 2/5![United Airlines logo]()
$562
This KLM deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:48 am
SGF
- BRU
1 stop14h 12m
KLM
Mon 3/309:45 am
BRU
- SGF
1 stop15h 26m
KLM
Deal found 2/5![KLM logo]()
$595
One-way flights from Missouri to BrusselsSearch for one-way flight options from Missouri to Brussels. Find affordable one-way fares based on user searches. Data last updated February 8, 2026.
Search for one-way flight options from Missouri to Brussels. Find affordable one-way fares based on user searches. Data last updated February 8, 2026.
This FlightHub deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:24 am
MCI
- BRU
2 stops19h 16m
Aer Lingus
Deal found 2/6![Aer Lingus logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2612:12 pm
MCI
- BRU
3 stops45h 48m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$336
This FlightHub deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:10 pm
MCI
- BRU
2 stops32h 30m
Aer Lingus
Deal found 2/8![Aer Lingus logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:00 am
MCI
- BRU
3 stops46h 55m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
MCI
- BRU
3 stops43h 20m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:55 pm
STL
- BRU
3 stops34h 00m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
MCI
- BRU
3 stops28h 25m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:15 am
MCI
- BRU
2 stops30h 45m
United Airlines
Deal found 2/6![United Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:50 pm
MCI
- BRU
1 stop11h 25m
United Airlines
Deal found 2/8![United Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2212:30 pm
MCI
- BRU
2 stops17h 45m
United Airlines
Deal found 2/5![United Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:21 am
STL
- BRU
3 stops48h 49m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$414
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:13 am
MCI
- BRU
3 stops42h 42m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$416
Find flight deals from Missouri to Brussels
Keep the following information in mind while searching for Missouri to Brussels flight deals. Data was last updated February 8, 2026.
Round-trip from | $486 (United Airlines) |
|---|---|
One-way from | $328 (FlightHub) |
Popular in | December |
Cheapest in | February |
Average price | $494 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Missouri to Brussels that are best for you.
Fly from
Missouri
Fly to
Brussels
Route
Depart
Return
Price
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Tue 3/17
11:25 am-1:15 pm
2 stops19h 50m
Brussels Bruxelles-National
Tue 3/24
10:00 am-6:00 pm
2 stops38h 00m
$486
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Wed 3/18
4:05 pm-1:15 pm
2 stops15h 10m
Brussels Bruxelles-National
Wed 3/25
10:00 am-6:00 pm
2 stops38h 00m
$490
JoplinBrussels
JLN - BRU
JLNBRU
Joplin
Wed 3/4
6:19 pm-1:15 pm
2 stops35h 56m
Brussels Bruxelles-National
Sun 3/8
10:10 am-5:43 pm
1 stop13h 33m
$501
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Fri 3/20
5:54 am-8:00 am
1 stop20h 06m
Brussels Bruxelles-National
Thu 3/26
10:00 am-7:56 pm
1 stop15h 56m
$509
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Mon 4/27
4:30 pm-7:10 pm
2 stops19h 40m
Brussels Bruxelles-National
Fri 5/8
10:45 am-11:56 pm
2 stops20h 11m
$510
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Wed 3/18
4:50 pm-10:10 am
1 stop11h 20m
Brussels Bruxelles-National
Wed 3/25
12:45 pm-10:59 pm
2 stops16h 14m
$513
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Wed 3/18
12:04 pm-8:00 am
1 stop13h 56m
Brussels Bruxelles-National
Wed 3/25
2:45 pm-9:05 am
2 stops24h 20m
$519
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Thu 4/9
7:45 am-9:00 am
1 stop18h 15m
Brussels Bruxelles-National
Fri 4/17
9:25 am-12:22 pm
2 stops33h 57m
$538
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Wed 5/6
3:22 pm-9:00 am
1 stop10h 38m
Brussels Bruxelles-National
Mon 5/11
9:25 am-2:26 pm
2 stops36h 01m
$538
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Mon 4/27
10:00 am-9:00 am
1 stop16h 00m
Brussels Bruxelles-National
Fri 5/8
9:25 am-8:05 pm
1 stop17h 40m
$551
Showing 1-10 of 42 results
Best time to book a flight from Missouri to Brussels
Have a flexible travel schedule? Discover the best time to fly to Brussels from Missouri with our price prediction graph.
MCI-BRU
STL-BRU
STL-CRL
JLN-BRU
SGF-BRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Brussels
USMO-BR1
MCI-BRU
STL-BRU
STL-CRL
JLN-BRU
What is the cheapest month to book a flight from Missouri to Brussels?
Currently, April is the cheapest month in which you can book a flight from Missouri to Brussels (average of $443). Flying from Missouri to Brussels in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to Brussels
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Brussels by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Brussels by cabin class
Find flights from Missouri to Brussels, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Brussels flights
Browse other Missouri and Brussels flight options. Last updated on February 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Brussels flights
Consider these flights traveling from Missouri to Brussels.
Top 2 airlines flying from Missouri to Brussels
Discover the top 2 airlines that operate flights from Missouri to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$441 | Average$2,205 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$506 | Average$747 | FlexibilityNo cancel fee | On-time69% |