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$480+ Cheap flights from Missouri to Brussels

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BRU
dic. 10 — dic. 171
mié. 12/10
mié. 12/17
1 adult, Economy
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Cheap flight deals from Missouri to Brussels

Keep the following information in mind while searching for Missouri to Brussels flight deals. Data was last updated noviembre 10, 2025.

Round-trip from

$480
(United Airlines)

Popular in

December

Cheapest in

November

Average price

$680
From Missouri to Brussels
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($305 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($111 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
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Find flight deals from Missouri to Brussels

Cheapest flights from Missouri to Brussels
Explore the most affordable flight options available from Missouri to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 10, 2025.

This KAYAK deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2711:04 amSTL - BRU
2 stops39h 36mScandinavian Airlines
jue. 12/410:20 amBRU - STL
2 stops20h 22mScandinavian Airlines
Deal found 11/8$678
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2710:00 amSTL - BRU
1 stop15h 55mUnited Airlines
jue. 12/410:00 amBRU - STL
2 stops35h 23mUnited Airlines
Deal found 11/8$684
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/153:19 pmSTL - BRU
2 stops14h 56mUnited Airlines
jue. 12/2511:55 amBRU - STL
1 stop14h 27mUnited Airlines
Deal found 11/9$723
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/2411:24 amSGF - BRU
2 stops18h 51mUnited Airlines
mié. 12/312:25 pmBRU - SGF
2 stops31h 13mUnited Airlines
Deal found 11/9$769
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/237:02 pmSTL - BRU
2 stops29h 33mDelta
mar. 12/306:15 amBRU - STL
2 stops23h 01mDelta
Deal found 11/8$773
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/246:24 pmJLN - BRU
2 stops15h 51mUnited Airlines
mié. 12/312:25 pmBRU - JLN
2 stops40h 19mUnited Airlines
Deal found 11/9$775
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/246:24 pmJLN - BRU
2 stops18h 31mMultiple Airlines
mié. 12/3110:10 amBRU - JLN
1 stop12h 59mMultiple Airlines
Deal found 11/9$798
This Cheapflightsfares deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/138:39 amSTL - BRU
2 stops17h 56mAer Lingus
jue. 11/2010:15 amBRU - STL
2 stops20h 41mAer Lingus
Deal found 11/8$1,059
This eDestinos deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:00 amSTL - BRU
2 stops20h 35mAer Lingus
dom. 11/168:50 pmBRU - STL
2 stops31h 10mAer Lingus
Deal found 11/8$1,111
This Lufthansa deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/243:50 pmSTL - BRU
1 stop18h 40mLufthansa
mié. 12/317:00 amBRU - STL
1 stop13h 55mLufthansa
Deal found 11/9$1,113
This Mytrip deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/216:43 pmMCI - BRU
1 stop31h 12mMultiple Airlines
dom. 11/3010:00 amBRU - MCI
2 stops55h 39mMultiple Airlines
Deal found 11/9$1,176
This KLM deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/234:55 pmSTL - BRU
1 stop33h 05mKLM
mar. 12/3010:45 amBRU - STL
2 stops16h 56mKLM
Deal found 11/8$1,181

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 10, 2025.
Use the filters below to find and compare flights from Missouri to Brussels that are best for you.

Fly from

Missouri

Fly to

Brussels

Route

Depart

Return

Price

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

dom. 2/1

3:24 pm-1:15 pm

2 stops14h 51m

Brussels Bruxelles-National

mar. 2/10

10:00 am-5:41 pm

2 stops38h 41m

$480

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

dom. 2/1

12:35 pm-7:15 am

1 stop11h 40m

Brussels Bruxelles-National

mar. 2/10

10:00 am-3:10 pm

2 stops36h 10m

$484

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

mié. 1/28

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

mié. 2/4

10:10 am-5:43 pm

1 stop14h 33m

$505

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

vie. 1/30

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

lun. 2/2

10:10 am-10:58 pm

1 stop19h 48m

$505

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

mié. 1/28

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

mar. 2/3

10:10 am-9:13 pm

1 stop18h 03m

$505

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

vie. 1/30

11:20 am-8:55 am

1 stop14h 35m

Brussels Bruxelles-National

mié. 2/4

10:10 am-4:03 pm

1 stop12h 53m

$507

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

jue. 1/29

11:22 am-8:05 am

1 stop13h 43m

Brussels Bruxelles-National

mar. 2/3

11:15 am-5:18 pm

1 stop13h 03m

$507

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

mié. 1/28

1:15 pm-8:55 am

1 stop12h 40m

Brussels Bruxelles-National

lun. 2/2

11:15 am-5:18 pm

1 stop13h 03m

$507

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

jue. 1/29

9:59 am-7:35 am

2 stops14h 36m

Brussels Bruxelles-National

mié. 2/4

10:45 am-8:39 pm

2 stops16h 54m

$526

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

jue. 11/27

11:04 am-9:40 am

2 stops39h 36m

Brussels Bruxelles-National

jue. 12/4

10:20 am-11:42 pm

2 stops20h 22m

$678

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/7

Showing 1-10 of 22 results
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Best time to book a flight from Missouri to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Brussels

What is the cheapest month to book a flight from Missouri to Brussels?

Currently, November is the cheapest month in which you can book a flight from Missouri to Brussels (average of $592). Flying from Missouri to Brussels in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BRU?

Find hourly flight availability from Missouri to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 10, 2025.

It’s optimal to fly from Missouri to Brussels in the afternoon. By choosing this option you can save up to 25% on the cost of your flight, compared to a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Brussels?

    A quick flight from Missouri to Brussels can take about 11h 40m. United Airlines provides one of the quickest options available for as low as $484. Missouri and Brussels are separated by a distance of 4528 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Missouri to Brussels?

    When deciding which route to take from Missouri to Brussels consider Lambert-St Louis - Brussels Bruxelles-National, Kansas City - Brussels Bruxelles-National or Springfield-Branson - Brussels Bruxelles-National as they are the most popular.

  • Can I find deals for flights from Missouri to Brussels that include hotel bookings?

    Yes. In addition to deals on Missouri to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Brussels.

  • Can I find deals for business class flights from Missouri to Brussels?

    Yes. Cheapflights offers flight deals from Missouri to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Brussels?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Brussels (average of $592). Flying from Missouri to Brussels in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Missouri to Brussels

Discover the top 2 airlines that operate flights from Missouri to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$640Average$1,021FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$829Average$2,205FlexibilityNo cancel feeOn-time76%

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