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$341+ Cheap flights from Missouri to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BRU
nov. 13 — nov. 201
jue. 11/13
jue. 11/20
1 adult, Economy
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Cheap flight deals from Missouri to Brussels

Keep the following information in mind while searching for Missouri to Brussels flight deals. Data was last updated octubre 14, 2025.

Round-trip from

$525
(United Airlines)

One-way from

$341
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$873
From Missouri to Brussels
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One-way flight from Missouri to Brussels
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Highest demand for flights based on searches. 18% potential increase in price ($208 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Missouri to Brussels

Cheapest flights from Missouri to Brussels
Explore the most affordable flight options available from Missouri to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 14, 2025.

This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/147:45 amJLN - BRU
2 stops22h 30mUnited Airlines
mar. 11/1810:00 amBRU - JLN
2 stops44h 30mUnited Airlines
Deal found 10/13$525
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/286:15 amSGF - BRU
2 stops24h 00mUnited Airlines
vie. 12/510:00 amBRU - SGF
2 stops43h 13mUnited Airlines
Deal found 10/14$530
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/121:10 pmSTL - BRU
2 stops17h 05mUnited Airlines
jue. 11/2710:00 amBRU - STL
2 stops35h 24mUnited Airlines
Deal found 10/14$530
This Air Canada deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/124:05 pmSTL - BRU
2 stops14h 10mAir Canada
jue. 11/2710:00 amBRU - STL
2 stops35h 24mAir Canada
Deal found 10/14$532
This Flighttix deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/98:00 amMCI - BRU
2 stops16h 50mMultiple Airlines
dom. 11/1611:15 amBRU - MCI
1 stop16h 55mMultiple Airlines
Deal found 10/12$534
This Flighttix deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/912:45 pmMCI - BRU
1 stop11h 30mLufthansa
dom. 11/1611:15 amBRU - MCI
1 stop16h 55mLufthansa
Deal found 10/12$538
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1011:36 amMCI - BRU
2 stops18h 39mUnited Airlines
dom. 11/1611:15 amBRU - MCI
1 stop16h 55mUnited Airlines
Deal found 10/13$546
This Mytrip deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:00 amMCI - BRU
2 stops18h 50mAir Canada
dom. 11/1610:00 amBRU - MCI
2 stops53h 56mAir Canada
Deal found 10/12$550
This Flighttix deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2710:00 amSTL - BRU
1 stop15h 55mLufthansa
jue. 12/410:10 amBRU - STL
1 stop13h 53mLufthansa
Deal found 10/12$555
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3110:05 amMCI - BRU
2 stops20h 10mUnited Airlines
vie. 1/910:10 amBRU - MCI
2 stops30h 21mUnited Airlines
Deal found 10/12$557
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/317:40 amMCI - BRU
2 stops22h 35mUnited Airlines
jue. 1/84:55 pmBRU - MCI
2 stops28h 32mUnited Airlines
Deal found 10/12$572
This Flysmarter deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:43 pmMCI - BRU
3 stops31h 12mAir Canada
dom. 11/169:30 amBRU - MCI
2 stops19h 58mAir Canada
Deal found 10/13$575

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
Use the filters below to find and compare flights from Missouri to Brussels that are best for you.

Fly from

Missouri

Fly to

Brussels

Route

Depart

Return

Price

JoplinBrussels

JLN - BRU

JLNBRU

Joplin

vie. 11/14

7:45 am-1:15 pm

2 stops22h 30m

Brussels Bruxelles-National

mar. 11/18

10:00 am-11:30 pm

2 stops44h 30m

$525

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

mié. 11/12

1:10 pm-1:15 pm

2 stops17h 05m

Brussels Bruxelles-National

jue. 11/27

10:00 am-3:46 pm

2 stops36h 46m

$530

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

jue. 11/27

8:25 am-8:55 am

2 stops41h 30m

Brussels Bruxelles-National

jue. 12/4

10:00 am-2:23 pm

2 stops35h 23m

$530

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

mié. 12/10

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

lun. 2/9

10:00 am-12:29 pm

2 stops33h 29m

$532

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

mié. 12/10

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

lun. 2/9

10:00 am-12:29 pm

2 stops33h 29m

$532

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

mié. 11/12

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

jue. 11/27

10:00 am-2:24 pm

2 stops35h 24m

$532

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

dom. 11/9

8:00 am-7:50 am

2 stops16h 50m

Brussels Bruxelles-National

dom. 11/16

11:15 am-9:10 pm

1 stop16h 55m

$534

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

lun. 11/10

3:25 pm-1:15 pm

2 stops14h 50m

Brussels Bruxelles-National

dom. 11/16

11:55 am-8:56 am

2 stops28h 01m

$546

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

jue. 1/8

12:35 pm-1:15 pm

2 stops17h 40m

Brussels Bruxelles-National

dom. 1/11

10:10 am-7:57 pm

1 stop16h 47m

$553

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

mié. 1/7

1:42 pm-1:15 pm

2 stops16h 33m

Brussels Bruxelles-National

dom. 1/11

10:10 am-9:59 pm

1 stop18h 49m

$553

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 23 results
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Best time to book a flight from Missouri to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Brussels

What is the cheapest month to book a flight from Missouri to Brussels?

Currently, October is the cheapest month in which you can book a flight from Missouri to Brussels (average of $604). Flying from Missouri to Brussels in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BRU?

Find hourly flight availability from Missouri to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 14, 2025.

It’s optimal to fly from Missouri to Brussels in the afternoon. By choosing this option you can save up to 25% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Missouri to Brussels?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Brussels?

    A quick flight from Missouri to Brussels can take about 14h 10m. United Airlines provides one of the quickest options available for as low as $532. Missouri and Brussels are separated by a distance of 4393 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Brussels one-way?

    $431 is the cheapest one-way deal found within the past few days, from Lufthansa. You may also be able to find cheap deals on Air Canada and United Airlines, with prices starting from $439 and $443, respectively.

  • What are the most popular routes from Missouri to Brussels?

    When deciding which route to take from Missouri to Brussels consider Lambert-St Louis - Brussels Bruxelles-National, Kansas City - Brussels Bruxelles-National or Joplin - Brussels Bruxelles-National as they are the most popular.

  • Can I find deals for flights from Missouri to Brussels that include hotel bookings?

    Yes. In addition to deals on Missouri to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Brussels.

  • Can I find deals for business class flights from Missouri to Brussels?

    Yes. Cheapflights offers flight deals from Missouri to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Brussels?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Brussels (average of $604). Flying from Missouri to Brussels in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Missouri to Brussels

Discover the top airline that operate flights from Missouri to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$640Average$1,105FlexibilityNo cancel feeOn-time69%

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