$190+ Cheap flights from Portland (PDX) to Biloxi, MS
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — MSY
Jul 2 — Jul 91
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Biloxi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Biloxi
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Best
Last-minute
One-way
Cheapest flights from Portland to BiloxiExplore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 2, 2026.
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 2, 2026.
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:41 pm
PDX
- GPT
1 stop9h 13m
American Airlines
Wed 7/297:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 5/29![American Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:41 pm
PDX
- GPT
1 stop9h 14m
American Airlines
Wed 7/297:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 5/30![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:59 pm
PDX
- GPT
1 stop8h 52m
American Airlines
Sat 10/246:27 pm
GPT
- PDX
1 stop6h 46m
American Airlines
Deal found 5/29![American Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:41 pm
PDX
- GPT
1 stop9h 14m
American Airlines
Mon 7/277:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 5/29![American Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:40 pm
PDX
- GPT
2 stops11h 45m
United Airlines
Wed 7/292:00 pm
GPT
- PDX
1 stop7h 18m
United Airlines
Deal found 5/29![United Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:56 am
PDX
- GPT
1 stop7h 15m
United Airlines
Wed 10/285:15 pm
GPT
- PDX
1 stop7h 56m
United Airlines
Deal found 6/1![United Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:34 pm
PDX
- GPT
1 stop7h 27m
American Airlines
Tue 7/147:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 5/29![American Airlines logo]()
$441
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:40 am
PDX
- GPT
1 stop8h 08m
American Airlines
Wed 6/177:50 pm
GPT
- PDX
1 stop7h 00m
American Airlines
Deal found 5/29![American Airlines logo]()
$455
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:40 pm
PDX
- GPT
2 stops12h 45m
United Airlines
Mon 7/275:19 pm
GPT
- PDX
1 stop7h 29m
United Airlines
Deal found 5/29![United Airlines logo]()
$457
Best flights from Portland to BiloxiDiscover carefully curated flight deals from Portland to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 2, 2026.
Discover carefully curated flight deals from Portland to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 2, 2026.
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:41 pm
PDX
- GPT
1 stop9h 13m
American Airlines
Wed 7/297:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 6/1![American Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:40 pm
PDX
- GPT
2 stops11h 45m
United Airlines
Wed 7/292:00 pm
GPT
- PDX
1 stop7h 18m
United Airlines
Deal found 5/29![United Airlines logo]()
$422
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:55 pm
PDX
- GPT
2 stops12h 40m
Delta
Sat 10/246:00 am
GPT
- PDX
2 stops12h 27m
Delta
Deal found 5/29![Delta logo]()
$619
This Alaska Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:32 am
PDX
- GPT
2 stops13h 29m
Alaska Airlines
Tue 7/1411:27 am
GPT
- PDX
2 stops11h 04m
Alaska Airlines
Deal found 5/30![Alaska Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:56 am
PDX
- GPT
1 stop7h 15m
United Airlines
Wed 10/285:15 pm
GPT
- PDX
1 stop7h 56m
United Airlines
Deal found 6/1![United Airlines logo]()
$427
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:40 pm
PDX
- GPT
2 stops12h 45m
United Airlines
Mon 7/275:19 pm
GPT
- PDX
1 stop7h 29m
United Airlines
Deal found 5/29![United Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:15 pm
PDX
- GPT
2 stops14h 06m
United Airlines
Sat 10/242:00 pm
GPT
- PDX
1 stop7h 18m
United Airlines
Deal found 5/29![United Airlines logo]()
$484
Last-minute flights from Portland to BiloxiDiscover last-minute flight deals from Portland to Biloxi. Data last updated June 2, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Biloxi. Data last updated June 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:43 pm
PDX
- GPT
1 stop9h 09m
American Airlines
Wed 6/177:50 pm
GPT
- PDX
1 stop7h 00m
American Airlines
Deal found 5/29![American Airlines logo]()
$455
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:43 pm
PDX
- GPT
1 stop9h 09m
American Airlines
Fri 6/127:50 pm
GPT
- PDX
1 stop7h 00m
American Airlines
Deal found 6/1![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:34 pm
PDX
- GPT
1 stop7h 27m
American Airlines
Tue 7/147:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 5/29![American Airlines logo]()
$441
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:41 pm
PDX
- GPT
1 stop9h 14m
American Airlines
Wed 7/297:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 5/30![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:41 pm
PDX
- GPT
1 stop9h 14m
American Airlines
Mon 7/277:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 5/29![American Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:40 pm
PDX
- GPT
2 stops12h 45m
United Airlines
Mon 7/275:19 pm
GPT
- PDX
1 stop7h 29m
United Airlines
Deal found 5/29![United Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:41 pm
PDX
- GPT
1 stop9h 13m
American Airlines
Wed 7/297:43 pm
GPT
- PDX
1 stop7h 12m
American Airlines
Deal found 5/29![American Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:40 pm
PDX
- GPT
2 stops11h 45m
United Airlines
Wed 7/292:00 pm
GPT
- PDX
1 stop7h 18m
United Airlines
Deal found 5/29![United Airlines logo]()
$422
One-way flights from Portland to BiloxiSearch for one-way flight options from Portland to Biloxi. Find affordable one-way fares based on user searches. Data last updated June 2, 2026.
Search for one-way flight options from Portland to Biloxi. Find affordable one-way fares based on user searches. Data last updated June 2, 2026.
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2812:40 am
PDX
- GPT
1 stop8h 12m
American Airlines
Deal found 5/31![American Airlines logo]()
$190
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:40 pm
PDX
- GPT
2 stops12h 45m
United Airlines
Deal found 5/31![United Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/299:48 pm
PDX
- GPT
3 stops33h 33m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$654
Find flight deals from Portland to Biloxi
Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated June 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $323 (American Airlines) |
One-way from | $190 (American Airlines) |
Popular in | March |
Cheapest in | October |
Average price | $417 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Fri 7/24
11:41 pm-10:54 am
1 stop9h 13m
Gulfport Biloxi Regional
Wed 7/29
7:43 pm-12:55 am
1 stop7h 12m
$323
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Fri 7/24
11:40 pm-1:25 pm
2 stops11h 45m
Gulfport Biloxi Regional
Wed 7/29
2:00 pm-7:18 pm
1 stop7h 18m
$422
Quickest round-trip
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Sat 10/24
6:56 am-4:11 pm
1 stop7h 15m
Gulfport Biloxi Regional
Wed 10/28
5:15 pm-11:11 pm
1 stop7h 56m
$427
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Wed 7/22
10:40 pm-1:25 pm
2 stops12h 45m
Gulfport Biloxi Regional
Mon 7/27
5:19 pm-10:48 pm
1 stop7h 29m
$457
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Sat 10/10
7:15 pm-11:21 am
2 stops14h 06m
Gulfport Biloxi Regional
Sat 10/24
2:00 pm-7:18 pm
1 stop7h 18m
$484
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Sat 10/10
10:55 pm-1:35 pm
2 stops12h 40m
Gulfport Biloxi Regional
Sat 10/24
6:00 am-4:27 pm
2 stops12h 27m
$619
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Wed 7/1
7:32 am-11:01 pm
2 stops13h 29m
Gulfport Biloxi Regional
Tue 7/14
11:27 am-8:31 pm
2 stops11h 04m
$664
Cheapest one-way
Quickest one-way
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Sun 6/28
12:40 am-10:52 am
1 stop8h 12m
$190
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Mon 6/29
10:40 pm-1:25 pm
2 stops12h 45m
$300
PortlandGulfport
PDX - GPT
PDXGPT
Portland
Mon 6/29
9:48 pm-9:21 am
3 stops33h 33m
$654
Sorted by cheapest first
Best time to book a flight from Portland to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
PDX-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Biloxi
PDX-B1L
PDX-GPT
How much does it cost to fly round-trip from Portland to Biloxi?
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated June 2, 2026.
Read through reviews of airlines operating flights from Portland to Biloxi, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Biloxi
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Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Portland to Biloxi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Biloxi flights
Browse other Portland and Biloxi flight options. Last updated on June 2, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on June 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Biloxi flights
Consider these flights traveling from Portland to Biloxi.
Top 5 airlines flying from Portland to Biloxi
Discover the top 5 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$129 | Average$449 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$188 | Average$333 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$188 | Average$424 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$197 | Average$369 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$236 | Average$434 | FlexibilityNo cancel fee | On-time69% |