HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Biloxi

$156+ Cheap flights from Portland (PDX) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — MSY
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Biloxi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated September 17, 2025.

Round-trip from

$279
(American Airlines)

One-way from

$156
(Kiwi.com)

Popular in

March

Cheapest in

October

Average price

$422
From Portland to Biloxi
Search Deals
One-way flight from Portland to Biloxi
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:07 pmPDX - GPT
1 stop7h 25mAmerican Airlines
Sat 12/66:14 pmGPT - PDX
1 stop7h 09mAmerican Airlines
Deal found 9/15$279
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:02 amPDX - GPT
1 stop7h 10mUnited Airlines
Wed 10/222:00 pmGPT - PDX
1 stop7h 13mUnited Airlines
Deal found 9/17$305
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:02 amPDX - GPT
1 stop7h 10mUnited Airlines
Tue 10/215:25 pmGPT - PDX
1 stop7h 02mUnited Airlines
Deal found 9/16$328
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/161:47 pmPDX - GPT
1 stop7h 20mAmerican Airlines
Fri 11/215:20 amGPT - PDX
1 stop7h 50mAmerican Airlines
Deal found 9/16$351
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:46 amPDX - GPT
1 stop7h 10mAmerican Airlines
Sat 11/812:10 pmGPT - PDX
2 stops9h 39mAmerican Airlines
Deal found 9/16$377
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:38 pmPDX - GPT
2 stops13h 39mUnited Airlines
Sat 11/81:57 pmGPT - PDX
2 stops10h 54mUnited Airlines
Deal found 9/16$403
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/101:51 pmPDX - GPT
1 stop7h 04mAmerican Airlines
Tue 10/141:15 pmGPT - PDX
1 stop8h 31mAmerican Airlines
Deal found 9/16$429

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Portland

Fly to

Biloxi

Route

Depart

Return

Price

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Wed 12/3

2:07 pm-11:32 pm

1 stop7h 25m

Gulfport Biloxi Regional

Sat 12/6

6:14 pm-11:23 pm

1 stop7h 09m

$279

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Tue 3/10

9:45 pm-9:41 am

1 stop9h 56m

Gulfport Biloxi Regional

Fri 3/13

10:30 am-8:47 pm

2 stops12h 17m

$299

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Wed 10/15

7:02 am-4:12 pm

1 stop7h 10m

Gulfport Biloxi Regional

Wed 10/22

2:00 pm-7:13 pm

1 stop7h 13m

$305

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Tue 10/14

7:02 am-4:12 pm

1 stop7h 10m

Gulfport Biloxi Regional

Tue 10/21

5:25 pm-10:27 pm

1 stop7h 02m

$328

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Wed 10/29

7:38 pm-11:17 am

2 stops13h 39m

Gulfport Biloxi Regional

Sat 11/8

1:57 pm-10:51 pm

2 stops10h 54m

$403

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Sat 2/21

9:45 pm-9:41 am

1 stop9h 56m

Gulfport Biloxi Regional

Wed 2/25

6:00 am-7:11 pm

2 stops15h 11m

$428

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Wed 10/22

12:43 pm-7:15 pm

2 stops28h 32m

$156

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Wed 10/22

11:55 pm-11:06 am

1 stop9h 11m

$189

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Thu 10/23

12:43 pm-8:59 am

2 stops18h 16m

$196

PortlandGulfport

PDX - GPT

PDXGPT

Portland

Thu 10/23

1:51 pm-10:55 pm

1 stop7h 04m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 12 results
1
2

Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

What is the cheapest month to book a flight from Portland to Biloxi?

Currently, August is the cheapest month in which you can book a flight from Portland to Biloxi (average of $256). Flying from Portland to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to B1L?

Find hourly flight availability from Portland to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Portland to Biloxi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Portland to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Portland to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Portland to Biloxi flight should consider departing on Monday at noon when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Portland to Biloxi?

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Portland to Biloxi, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    Most people fly from Portland (PDX) if they book a flight from Portland to Biloxi. On average, Portland has 0 outbound flights to Biloxi per day from 8 airlines. Portland is conveniently located just 6.0 mi from Portland’s city center.

  • How popular is this Portland to Biloxi flight route?

    The Portland to Biloxi flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Portland to Biloxi?

    For as low as $305, American Airlines can have you in Biloxi from Portland in 7h 10m. The distance from Portland to Biloxi is about 2082 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Portland to Biloxi?

    Looking for the cheapest flight from Portland to Biloxi? While on average our users pay $463, our data indicates the cheapest price to be $292. The most popular route (Portland - Gulfport Biloxi Regional), is priced around $299.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Biloxi?

    Currently, August is the cheapest month in which you can book a flight from Portland to Biloxi (average of $256). Flying from Portland to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 8 airlines flying from Portland to Biloxi

Discover the top 8 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$89Average$175FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$163Average$221FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$188Average$408FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$188Average$450FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$189Average$441FlexibilityNo cancel feeOn-time69%
DeltaCheapest$196Average$445FlexibilityNo cancel feeOn-timeN/A
Hawaiian AirlinesCheapest$198Average$406FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$256Average$459FlexibilityNo cancel feeOn-time75%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.