$161+ Cheap flights from Detroit (DTT) to Biloxi, MS
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — MSY
Jul 18 — Jul 251
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Biloxi with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Biloxi
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Best
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One-way
Cheapest flights from Detroit to BiloxiExplore the most affordable flight options available from Detroit to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
Explore the most affordable flight options available from Detroit to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:27 pm
DTW
- GPT
1 stop7h 18m
Multiple Airlines
Mon 8/175:31 pm
GPT
- DTW
1 stop18h 13m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:43 pm
DTW
- GPT
1 stop4h 52m
American Airlines
Wed 8/121:50 pm
GPT
- DTW
1 stop7h 40m
American Airlines
Deal found 6/14![American Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:27 pm
DTW
- GPT
1 stop7h 18m
Multiple Airlines
Sun 8/167:25 pm
GPT
- DTW
2 stops20h 15m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:31 pm
DTW
- GPT
1 stop24h 14m
Multiple Airlines
Mon 8/245:31 pm
GPT
- DTW
2 stops18h 36m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:58 pm
DTW
- GPT
1 stop4h 58m
American Airlines
Tue 7/76:35 pm
GPT
- DTW
1 stop5h 06m
American Airlines
Deal found 6/16![American Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:31 pm
DTW
- GPT
1 stop24h 14m
Multiple Airlines
Sun 8/237:25 pm
GPT
- DTW
2 stops20h 15m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:30 am
DTW
- GPT
1 stop7h 05m
Delta
Tue 10/136:00 am
GPT
- DTW
1 stop4h 22m
Delta
Deal found 6/17![Delta logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/162:56 pm
DTW
- GPT
2 stops17h 45m
Multiple Airlines
Sun 8/237:25 pm
GPT
- DTW
1 stop15h 22m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$346
Best flights from Detroit to BiloxiDiscover carefully curated flight deals from Detroit to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
Discover carefully curated flight deals from Detroit to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:58 pm
DTW
- GPT
1 stop4h 58m
American Airlines
Tue 7/76:35 pm
GPT
- DTW
1 stop5h 06m
American Airlines
Deal found 6/15![American Airlines logo]()
$316
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:24 pm
DTW
- GPT
1 stop4h 57m
Delta
Mon 8/176:00 pm
GPT
- DTW
1 stop4h 46m
Delta
Deal found 6/17![Delta logo]()
$401
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:30 am
DTW
- GPT
2 stops9h 42m
United Airlines
Sat 8/152:00 pm
GPT
- DTW
1 stop7h 30m
United Airlines
Deal found 6/17![United Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:10 pm
DTW
- GPT
1 stop7h 51m
American Airlines
Fri 7/37:04 am
GPT
- DTW
1 stop7h 25m
American Airlines
Deal found 6/18![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:37 am
DTW
- GPT
1 stop6h 15m
American Airlines
Sat 6/276:38 pm
GPT
- DTW
1 stop4h 55m
American Airlines
Deal found 6/16![American Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/277:58 pm
DTW
- GPT
1 stop5h 01m
American Airlines
Tue 6/307:04 am
GPT
- DTW
2 stops10h 34m
American Airlines
Deal found 6/15![American Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:37 am
DTW
- GPT
1 stop6h 15m
American Airlines
Fri 7/37:04 am
GPT
- DTW
2 stops9h 37m
American Airlines
Deal found 6/16![American Airlines logo]()
$457
Last-minute flights from Detroit to BiloxiDiscover last-minute flight deals from Detroit to Biloxi. Data last updated June 18, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Biloxi. Data last updated June 18, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/274:15 pm
DTW
- GPT
1 stop7h 46m
American Airlines
Tue 6/306:38 pm
GPT
- DTW
1 stop4h 55m
American Airlines
Deal found 6/17![American Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:10 pm
DTW
- GPT
1 stop7h 51m
American Airlines
Fri 7/37:04 am
GPT
- DTW
1 stop7h 25m
American Airlines
Deal found 6/18![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:37 am
DTW
- GPT
1 stop6h 15m
American Airlines
Sat 7/410:36 am
GPT
- DTW
1 stop7h 37m
American Airlines
Deal found 6/16![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:58 pm
DTW
- GPT
1 stop4h 58m
American Airlines
Tue 7/76:35 pm
GPT
- DTW
1 stop5h 06m
American Airlines
Deal found 6/16![American Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:37 am
DTW
- GPT
1 stop6h 18m
American Airlines
Sat 7/1110:36 am
GPT
- DTW
2 stops10h 08m
American Airlines
Deal found 6/16![American Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:17 am
DTW
- GPT
1 stop5h 02m
Delta
Mon 7/275:57 pm
GPT
- DTW
1 stop4h 47m
Delta
Deal found 6/16![Delta logo]()
$380
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:09 pm
DTW
- GPT
1 stop5h 05m
Delta
Fri 7/245:57 pm
GPT
- DTW
1 stop6h 02m
Delta
Deal found 6/17![Delta logo]()
$401
One-way flights from Detroit to BiloxiSearch for one-way flight options from Detroit to Biloxi. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
Search for one-way flight options from Detroit to Biloxi. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:40 pm
DTW
- GPT
2 stops26h 05m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/912:27 pm
DTW
- GPT
1 stop7h 18m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:30 am
DTW
- GPT
2 stops26h 11m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:42 pm
DTW
- GPT
2 stops43h 59m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:15 am
DTW
- GPT
1 stop8h 09m
United Airlines
Deal found 6/13![United Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:15 am
DTW
- GPT
1 stop8h 10m
United Airlines
Deal found 6/17![United Airlines logo]()
$364
Find flight deals from Detroit to Biloxi
Keep the following information in mind while searching for Detroit to Biloxi flight deals. Data was last updated June 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (Kiwi.com) |
One-way from | $161 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Detroit to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Fri 7/3
7:58 pm-11:56 pm
1 stop4h 58m
Gulfport Biloxi Regional
Tue 7/7
6:35 pm-12:41 am
1 stop5h 06m
$316
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Tue 6/30
4:10 pm-11:01 pm
1 stop7h 51m
Gulfport Biloxi Regional
Fri 7/3
7:04 am-3:29 pm
1 stop7h 25m
$381
Quickest round-trip
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Fri 8/14
6:24 pm-10:21 pm
1 stop4h 57m
Gulfport Biloxi Regional
Mon 8/17
6:00 pm-11:46 pm
1 stop4h 46m
$401
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Wed 6/24
5:37 am-10:52 am
1 stop6h 15m
Gulfport Biloxi Regional
Sat 6/27
6:38 pm-12:33 am
1 stop4h 55m
$402
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Sat 6/27
7:58 pm-11:59 pm
1 stop5h 01m
Gulfport Biloxi Regional
Tue 6/30
7:04 am-6:38 pm
2 stops10h 34m
$407
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Thu 8/13
7:30 am-4:12 pm
2 stops9h 42m
Gulfport Biloxi Regional
Sat 8/15
2:00 pm-10:30 pm
1 stop7h 30m
$454
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Wed 7/1
5:37 am-10:52 am
1 stop6h 15m
Gulfport Biloxi Regional
Fri 7/3
7:04 am-5:41 pm
2 stops9h 37m
$457
Cheapest one-way
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Thu 7/9
12:27 pm-6:45 pm
1 stop7h 18m
$177
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Wed 8/19
5:40 pm-6:45 pm
3 stops26h 05m
$178
DetroitGulfport
DTW - GPT
DTWGPT
Detroit Metropolitan Wayne County
Thu 7/2
6:30 am-7:41 am
2 stops26h 11m
$239
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from Detroit to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from Detroit with our price prediction graph.
DTW-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Biloxi
DTT-B1L
DTW-GPT
What is the cheapest time of day to fly from DTT to B1L?
Find hourly flight availability from Detroit to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2026.
When flying from Detroit to Biloxi, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 66% versus a flight in the afternoon.
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated June 18, 2026.
Read through reviews of airlines operating flights from Detroit to Biloxi, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Detroit to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to Biloxi
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Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Detroit to Biloxi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and Biloxi flights
Browse other Detroit and Biloxi flight options. Last updated on June 18, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on June 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 6 airlines flying from Detroit to Biloxi
Discover the top 6 airlines that operate flights from Detroit to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$85 | Average$246 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$198 | Average$377 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$246 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$219 | Average$349 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$223 | Average$440 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$258 | Average$337 | FlexibilityNo cancel fee | On-time69% |