$115+ Cheap flights from Portland (PDX) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Jul 12 — Jul 191
Round-trip
1 adult, Economy
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Find cheap flights from Portland to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Portland to South CarolinaExplore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from Portland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:35 pm
PDX
- CHS
1 stop10h 32m
Delta
Tue 8/113:14 pm
CHS
- PDX
1 stop8h 03m
Delta
Deal found 6/9![Delta logo]()
$229
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:02 pm
PDX
- GSP
1 stop7h 33m
United Airlines
Tue 9/154:33 pm
GSP
- PDX
1 stop7h 32m
United Airlines
Deal found 6/10![United Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:45 pm
PDX
- CHS
1 stop8h 57m
Delta
Sat 11/76:30 am
CHS
- PDX
1 stop7h 26m
Delta
Deal found 6/11![Delta logo]()
$251
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:35 pm
PDX
- CHS
1 stop10h 32m
Delta
Mon 8/106:15 am
CHS
- PDX
1 stop7h 12m
Delta
Deal found 6/8![Delta logo]()
$252
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:02 pm
PDX
- CHS
1 stop8h 39m
United Airlines
Wed 9/232:54 pm
CHS
- PDX
1 stop8h 16m
United Airlines
Deal found 6/11![United Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:30 pm
PDX
- GSP
2 stops10h 00m
Southwest
Tue 9/151:20 pm
GSP
- PDX
2 stops11h 55m
Southwest
Deal found 6/10![Southwest logo]()
$258
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:06 pm
PDX
- MYR
1 stop9h 14m
American Airlines
Tue 10/64:26 pm
MYR
- PDX
1 stop9h 47m
American Airlines
Deal found 6/10![American Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:35 pm
PDX
- CHS
1 stop10h 32m
Delta
Mon 8/245:10 am
CHS
- PDX
1 stop8h 17m
Delta
Deal found 6/10![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:30 pm
PDX
- CHS
1 stop8h 55m
Southwest
Wed 9/236:45 am
CHS
- PDX
2 stops11h 15m
Southwest
Deal found 6/11![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:00 pm
PDX
- CHS
1 stop11h 09m
Delta
Mon 9/285:33 pm
CHS
- PDX
1 stop7h 12m
Delta
Deal found 6/11![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:35 am
PDX
- CHS
1 stop7h 59m
United Airlines
Fri 8/214:30 pm
CHS
- PDX
1 stop7h 35m
United Airlines
Deal found 6/8![United Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:44 pm
PDX
- MYR
1 stop7h 51m
American Airlines
Tue 9/1512:10 pm
MYR
- PDX
1 stop8h 42m
American Airlines
Deal found 6/11![American Airlines logo]()
$312
Best flights from Portland to South CarolinaDiscover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from Portland to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:30 pm
PDX
- GSP
2 stops10h 00m
Southwest
Tue 9/151:20 pm
GSP
- PDX
2 stops11h 55m
Southwest
Deal found 6/10![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:35 pm
PDX
- CHS
1 stop10h 32m
Delta
Mon 8/245:10 am
CHS
- PDX
1 stop8h 17m
Delta
Deal found 6/10![Delta logo]()
$275
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:00 am
PDX
- GSP
1 stop7h 15m
United Airlines
Fri 8/284:33 pm
GSP
- PDX
1 stop9h 21m
United Airlines
Deal found 6/9![United Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:59 pm
PDX
- CLT
Nonstop4h 56m
American Airlines
Tue 8/185:20 pm
CLT
- PDX
Nonstop5h 28m
American Airlines
Deal found 6/7![American Airlines logo]()
$494
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:30 pm
PDX
- CHS
1 stop8h 55m
Southwest
Wed 9/236:45 am
CHS
- PDX
2 stops11h 15m
Southwest
Deal found 6/11![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:35 pm
PDX
- SAV
1 stop9h 12m
Delta
Tue 8/115:35 am
SAV
- PDX
1 stop7h 52m
Delta
Deal found 6/8![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:15 pm
PDX
- GSP
2 stops11h 20m
United Airlines
Tue 9/154:33 pm
GSP
- PDX
1 stop7h 32m
United Airlines
Deal found 6/11![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:45 pm
PDX
- CHS
1 stop7h 55m
Delta
Sat 11/72:25 pm
CHS
- PDX
2 stops12h 27m
Delta
Deal found 6/10![Delta logo]()
$346
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:45 am
PDX
- CHS
1 stop7h 05m
Southwest
Mon 11/166:35 am
CHS
- PDX
2 stops9h 35m
Southwest
Deal found 6/8![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:02 pm
PDX
- CAE
1 stop7h 41m
United Airlines
Wed 9/92:56 pm
CAE
- PDX
1 stop8h 14m
United Airlines
Deal found 6/8![United Airlines logo]()
$365
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:00 pm
PDX
- CHS
1 stop10h 22m
Delta
Fri 9/255:33 pm
CHS
- PDX
1 stop7h 12m
Delta
Deal found 6/11![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:40 pm
PDX
- CHS
1 stop8h 43m
United Airlines
Tue 7/146:00 am
CHS
- PDX
1 stop8h 38m
United Airlines
Deal found 6/11![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:35 pm
PDX
- SAV
2 stops9h 45m
Southwest
Sat 10/3112:05 pm
SAV
- PDX
2 stops10h 15m
Southwest
Deal found 6/8![Southwest logo]()
$388
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:55 pm
PDX
- CAE
1 stop9h 14m
Delta
Mon 9/143:53 pm
CAE
- PDX
1 stop8h 52m
Delta
Deal found 6/11![Delta logo]()
$360
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:59 pm
PDX
- CAE
1 stop8h 11m
United Airlines
Mon 11/165:25 pm
CAE
- PDX
1 stop7h 53m
United Airlines
Deal found 6/9![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/69:47 pm
PDX
- AGS
1 stop7h 42m
American Airlines
Mon 7/136:31 pm
AGS
- PDX
1 stop8h 24m
American Airlines
Deal found 6/12![American Airlines logo]()
$507
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:05 am
PDX
- MYR
1 stop8h 30m
Southwest
Mon 9/141:55 pm
MYR
- PDX
2 stops10h 15m
Southwest
Deal found 6/7![Southwest logo]()
$399
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:05 am
PDX
- CHS
1 stop11h 25m
Delta
Wed 7/155:00 pm
CHS
- PDX
1 stop7h 44m
Delta
Deal found 6/7![Delta logo]()
$372
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:11 am
PDX
- GSP
1 stop6h 49m
United Airlines
Wed 11/185:41 pm
GSP
- PDX
1 stop7h 37m
United Airlines
Deal found 6/8![United Airlines logo]()
$383
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:49 pm
PDX
- HHH
2 stops15h 24m
American Airlines
Tue 10/273:58 pm
HHH
- PDX
1 stop7h 28m
American Airlines
Deal found 6/8![American Airlines logo]()
$514
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:04 am
PDX
- CAE
1 stop7h 24m
Delta
Mon 11/167:00 am
CAE
- PDX
1 stop9h 25m
Delta
Deal found 6/9![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:44 pm
PDX
- HHH
1 stop8h 29m
American Airlines
Tue 10/2712:35 pm
HHH
- PDX
2 stops13h 29m
American Airlines
Deal found 6/8![American Airlines logo]()
$514
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:45 am
PDX
- GSP
2 stops8h 35m
Southwest
Mon 8/241:05 pm
GSP
- PDX
2 stops10h 40m
Southwest
Deal found 6/8![Southwest logo]()
$425
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:51 pm
PDX
- SAV
1 stop7h 24m
United Airlines
Wed 11/181:50 pm
SAV
- PDX
2 stops11h 48m
United Airlines
Deal found 6/12![United Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:55 pm
PDX
- GSP
1 stop9h 02m
Delta
Wed 7/155:16 pm
GSP
- PDX
1 stop7h 28m
Delta
Deal found 6/7![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:20 pm
PDX
- GSP
1 stop12h 50m
Southwest
Sat 8/11:55 pm
GSP
- PDX
2 stops11h 55m
Southwest
Deal found 6/11![Southwest logo]()
$429
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:49 am
PDX
- HHH
1 stop7h 36m
American Airlines
Tue 7/142:48 pm
HHH
- PDX
2 stops11h 03m
American Airlines
Deal found 6/11![American Airlines logo]()
$521
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:02 pm
PDX
- CHS
2 stops12h 33m
United Airlines
Mon 8/2410:14 am
CHS
- PDX
2 stops15h 38m
United Airlines
Deal found 6/9![United Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:00 am
PDX
- GSP
1 stop9h 16m
Delta
Sat 7/115:16 pm
GSP
- PDX
1 stop7h 28m
Delta
Deal found 6/7![Delta logo]()
$392
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:45 am
PDX
- SAV
2 stops11h 00m
Southwest
Thu 10/17:25 pm
SAV
- PDX
1 stop7h 50m
Southwest
Deal found 6/11![Southwest logo]()
$438
Last-minute flights from Portland to South CarolinaDiscover last-minute flight deals from Portland to South Carolina. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to South Carolina. Data last updated June 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:30 pm
PDX
- GSP
1 stop7h 48m
Delta
Sat 7/113:06 pm
GSP
- PDX
1 stop9h 38m
Delta
Deal found 6/8![Delta logo]()
$392
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:49 am
PDX
- CHS
1 stop8h 49m
American Airlines
Mon 7/137:53 pm
CHS
- PDX
1 stop8h 02m
American Airlines
Deal found 6/10![American Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:55 pm
PDX
- GSP
1 stop7h 18m
Delta
Tue 7/143:06 pm
GSP
- PDX
1 stop9h 38m
Delta
Deal found 6/10![Delta logo]()
$395
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:49 am
PDX
- HHH
1 stop7h 36m
American Airlines
Tue 7/142:48 pm
HHH
- PDX
1 stop8h 57m
American Airlines
Deal found 6/11![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:40 pm
PDX
- CHS
1 stop10h 09m
Delta
Wed 7/155:00 pm
CHS
- PDX
1 stop7h 44m
Delta
Deal found 6/10![Delta logo]()
$372
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:50 pm
PDX
- CHS
2 stops11h 01m
United Airlines
Tue 7/146:00 am
CHS
- PDX
1 stop8h 38m
United Airlines
Deal found 6/10![United Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:40 pm
PDX
- GSP
1 stop8h 15m
United Airlines
Wed 7/156:10 am
GSP
- PDX
1 stop8h 28m
United Airlines
Deal found 6/7![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:07 am
PDX
- GSP
1 stop8h 29m
American Airlines
Tue 7/148:01 pm
GSP
- PDX
1 stop7h 54m
American Airlines
Deal found 6/10![American Airlines logo]()
$387
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:50 pm
PDX
- CHS
2 stops11h 01m
United Airlines
Wed 7/156:00 am
CHS
- PDX
1 stop8h 38m
United Airlines
Deal found 6/10![United Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/109:47 pm
PDX
- CAE
1 stop7h 34m
American Airlines
Tue 7/147:23 pm
CAE
- PDX
1 stop8h 32m
American Airlines
Deal found 6/9![American Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:40 pm
PDX
- CHS
1 stop10h 09m
Delta
Wed 8/55:10 am
CHS
- PDX
1 stop8h 17m
Delta
Deal found 6/8![Delta logo]()
$368
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:54 am
PDX
- CHS
1 stop8h 01m
American Airlines
Sat 8/17:12 pm
CHS
- PDX
1 stop8h 43m
American Airlines
Deal found 6/9![American Airlines logo]()
$387
One-way flights from Portland to South CarolinaSearch for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
Search for one-way flight options from Portland to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:45 pm
PDX
- CHS
1 stop8h 20m
Southwest
Deal found 6/8![Southwest logo]()
$115
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:05 pm
PDX
- CHS
1 stop10h 41m
Delta
Deal found 6/9![Delta logo]()
$129
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:45 pm
PDX
- GSP
1 stop14h 20m
Southwest
Deal found 6/8![Southwest logo]()
$130
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:30 pm
PDX
- MYR
2 stops11h 20m
Southwest
Deal found 6/9![Southwest logo]()
$136
This deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:20 am
PDX
- CHS
1 stop8h 46m
Alaska Airlines
Deal found 6/9![Alaska Airlines logo]()
$137
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:30 pm
PDX
- CLT
1 stop9h 25m
Southwest
Deal found 6/9![Southwest logo]()
$147
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/152:08 pm
PDX
- CHS
1 stop6h 51m
Delta
Deal found 6/9![Delta logo]()
$155
This deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:45 pm
PDX
- SAV
1 stop8h 32m
Delta
Deal found 6/9![Delta logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:16 pm
PDX
- CLT
2 stops20h 56m
Frontier
Deal found 6/12![Frontier logo]()
$164
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:20 pm
PDX
- CLT
1 stop9h 35m
Southwest
Deal found 6/11![Southwest logo]()
$178
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:50 am
PDX
- CHS
2 stops10h 55m
Southwest
Deal found 6/9![Southwest logo]()
$180
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:02 pm
PDX
- GSP
1 stop7h 34m
United Airlines
Deal found 6/12![United Airlines logo]()
$182
Find flight deals from Portland to South Carolina
Keep the following information in mind while searching for Portland to South Carolina flight deals. Data was last updated June 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $229 (Delta) |
One-way from | $115 (Southwest) |
Popular in | April |
Cheapest in | January |
Average price | $494 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Wed 9/9
11:30 pm-12:30 pm
2 stops10h 00m
Greenville
Tue 9/15
1:20 pm-10:15 pm
2 stops11h 55m
$258
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Thu 8/20
10:35 pm-12:07 pm
1 stop10h 32m
Charleston
Mon 8/24
5:10 am-10:27 am
1 stop8h 17m
$275
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Wed 9/9
11:30 pm-11:25 am
1 stop8h 55m
Charleston
Wed 9/23
6:45 am-3:00 pm
2 stops11h 15m
$295
PortlandSavannah
PDX - SAV
PDXSAV
Portland
Tue 8/4
10:35 pm-10:47 am
1 stop9h 12m
Savannah/Hilton Head
Tue 8/11
5:35 am-10:27 am
1 stop7h 52m
$313
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Tue 11/3
9:45 pm-8:40 am
1 stop7h 55m
Charleston
Sat 11/7
2:25 pm-11:52 pm
2 stops12h 27m
$346
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Mon 11/9
5:45 am-3:50 pm
1 stop7h 05m
Charleston
Mon 11/16
6:35 am-1:10 pm
2 stops9h 35m
$357
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Sun 9/20
11:00 pm-12:22 pm
1 stop10h 22m
Charleston
Fri 9/25
5:33 pm-9:45 pm
1 stop7h 12m
$357
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Wed 9/2
10:55 pm-11:09 am
1 stop9h 14m
Columbia Metropolitan
Mon 9/14
3:53 pm-9:45 pm
1 stop8h 52m
$360
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Sat 8/22
5:00 am-3:15 pm
1 stop7h 15m
Greenville
Fri 8/28
4:33 pm-10:54 pm
1 stop9h 21m
$363
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Wed 9/9
7:15 pm-9:35 am
2 stops11h 20m
Greenville
Tue 9/15
4:33 pm-9:05 pm
1 stop7h 32m
$364
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Portland with our price prediction graph.
PDX-CHS
PDX-CLT
PDX-MYR
PDX-CAE
PDX-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to South Carolina
PDX-USSC
PDX-CHS
PDX-CLT
PDX-MYR
PDX-CAE
What is the cheapest month to book a flight from Portland to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Portland to South Carolina (average of $129). Flying from Portland to South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to South Carolina?
How far ahead should I book a flight from Portland to South Carolina?
Booking 44 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2026.
See what other customers who have flown with Alaska Airlines,Southwest, andDelta from Portland to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.0
Reviews
1 / 20
4.0
OkayAnonymous,Jun 2026
SEA - RNO
Crew
8.5
Comfort
7.8
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.0
Reviews
1 / 20
4.0
OkayAnonymous,Jun 2026
SEA - RNO
Crew
8.5
Comfort
7.8
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.0
Reviews
1 / 20
4.0
OkayAnonymous,Jun 2026
SEA - RNO
Crew
8.5
Comfort
7.8
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.0
Reviews
1 / 20
4.0
OkayAnonymous,Jun 2026
SEA - RNO
Crew
8.5
Comfort
7.8
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.0
Reviews
1 / 20
4.0
OkayAnonymous,Jun 2026
SEA - RNO
Crew
8.5
Comfort
7.8
Food
7.0
Overall
7.9
Boarding
8.1
Entertainment
7.0
Reviews
1 / 20
4.0
OkayAnonymous,Jun 2026
SEA - RNO
Related info for your journey
Find useful and relevant information for your journey from Portland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to South Carolina by cabin class
Find flights from Portland to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and South Carolina flights
Browse other Portland and South Carolina flight options. Last updated on June 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to South Carolina flights
Consider these flights traveling from Portland to South Carolina.
Top 5 airlines flying from Portland to South Carolina
Discover the top 5 airlines that operate flights from Portland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$239 | Average$459 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$254 | Average$465 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$298 | Average$602 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$304 | Average$493 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$394 | Average$567 | FlexibilityNo cancel fee | On-time63% |