$133+ Cheap flights from Jacksonville (JAX) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
Jul 5 — Jul 121
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to South America
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Cheapest flights from Jacksonville to South AmericaExplore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
This KAYAK deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:05 am
JAX
- MDE
1 stop15h 05m
Multiple Airlines
Mon 9/219:45 am
MDE
- JAX
1 stop12h 35m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
Thu 9/179:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 6/2![United Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Mon 8/319:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 6/3![United Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
Mon 9/219:45 am
MDE
- JAX
2 stops48h 06m
United Airlines
Deal found 6/1![United Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
Sat 9/199:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 6/2![United Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:12 pm
JAX
- CTG
2 stops18h 53m
American Airlines
Tue 11/32:34 pm
CTG
- JAX
2 stops21h 08m
American Airlines
Deal found 6/4![American Airlines logo]()
$378
This Trip.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:20 am
JAX
- MDE
2 stops27h 55m
Multiple Airlines
Wed 8/266:25 am
MDE
- JAX
2 stops27h 00m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$411
This JetBlue deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 7/2212:35 pm
CTG
- JAX
1 stop6h 26m
JetBlue
Deal found 5/31![JetBlue logo]()
$429
This KAYAK deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:35 pm
JAX
- MDE
2 stops27h 35m
Multiple Airlines
Wed 7/229:45 am
MDE
- JAX
1 stop12h 35m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:28 pm
JAX
- CTG
1 stop20h 45m
American Airlines
Sat 7/41:35 pm
CTG
- JAX
1 stop18h 52m
American Airlines
Deal found 6/3![American Airlines logo]()
$439
This JetBlue deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Mon 7/2712:35 pm
CTG
- JAX
1 stop6h 26m
JetBlue
Deal found 6/5![JetBlue logo]()
$443
This Avianca deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 pm
JAX
- UIO
1 stop12h 35m
Multiple Airlines
Tue 9/295:25 pm
UIO
- JAX
1 stop20h 01m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$454
Best flights from Jacksonville to South AmericaDiscover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
Discover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
Thu 9/179:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 6/2![United Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:26 pm
JAX
- CTG
2 stops16h 39m
American Airlines
Mon 10/262:05 pm
CTG
- JAX
2 stops19h 11m
American Airlines
Deal found 6/4![American Airlines logo]()
$378
This Trip.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:20 am
JAX
- MDE
2 stops27h 55m
Multiple Airlines
Wed 8/266:25 am
MDE
- JAX
2 stops27h 00m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$411
This JetBlue deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 7/2212:35 pm
CTG
- JAX
1 stop6h 26m
JetBlue
Deal found 5/31![JetBlue logo]()
$429
This Delta deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/218:20 am
JAX
- CTG
2 stops16h 15m
Delta
Sat 7/42:30 pm
CTG
- JAX
1 stop8h 29m
Delta
Deal found 5/31![Delta logo]()
$475
This LATAM Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:10 pm
JAX
- BOG
2 stops25h 00m
LATAM Airlines
Sun 9/208:40 am
BOG
- JAX
2 stops24h 37m
LATAM Airlines
Deal found 6/3![LATAM Airlines logo]()
$575
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
Mon 9/219:45 am
MDE
- JAX
2 stops48h 06m
United Airlines
Deal found 6/1![United Airlines logo]()
$345
This JetBlue deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Mon 7/2712:35 pm
CTG
- JAX
1 stop6h 26m
JetBlue
Deal found 6/5![JetBlue logo]()
$443
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:11 pm
JAX
- CTG
2 stops19h 24m
American Airlines
Fri 7/103:17 pm
CTG
- JAX
2 stops20h 33m
American Airlines
Deal found 5/31![American Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:37 pm
JAX
- BAQ
1 stop20h 01m
American Airlines
Mon 7/201:34 pm
BAQ
- JAX
1 stop18h 53m
American Airlines
Deal found 6/1![American Airlines logo]()
$472
This oojo deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:36 pm
JAX
- UIO
2 stops20h 29m
Multiple Airlines
Mon 8/105:00 pm
UIO
- JAX
2 stops22h 32m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$556
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Wed 8/269:45 am
MDE
- JAX
3 stops34h 09m
United Airlines
Deal found 5/31![United Airlines logo]()
$518
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:10 pm
JAX
- BOG
1 stop18h 30m
Delta
Sun 9/202:55 pm
BOG
- JAX
1 stop7h 54m
Delta
Deal found 6/3![Delta logo]()
$576
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:37 pm
JAX
- CTG
1 stop19h 40m
American Airlines
Tue 8/43:17 pm
CTG
- JAX
1 stop7h 58m
American Airlines
Deal found 5/31![American Airlines logo]()
$479
This KAYAK deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 7/2212:35 pm
CTG
- JAX
1 stop25h 05m
JetBlue
Deal found 6/1![JetBlue logo]()
$535
This KAYAK deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:11 pm
JAX
- BOG
1 stop10h 14m
Multiple Airlines
Wed 9/168:30 am
BOG
- JAX
1 stop13h 50m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:35 pm
JAX
- MDE
2 stops27h 35m
United Airlines
Wed 7/159:45 am
MDE
- JAX
2 stops23h 59m
United Airlines
Deal found 6/2![United Airlines logo]()
$518
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:22 am
JAX
- BOG
1 stop8h 53m
Delta
Sun 9/272:55 pm
BOG
- JAX
1 stop16h 42m
Delta
Deal found 6/4![Delta logo]()
$580
This LATAM Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:51 pm
JAX
- LIM
2 stops17h 09m
LATAM Airlines
Thu 9/1012:05 pm
LIM
- JAX
1 stop10h 59m
LATAM Airlines
Deal found 6/1![LATAM Airlines logo]()
$646
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:35 pm
JAX
- CTG
1 stop19h 40m
American Airlines
Mon 8/173:15 pm
CTG
- JAX
1 stop23h 49m
American Airlines
Deal found 6/4![American Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:45 pm
JAX
- BOG
2 stops13h 09m
United Airlines
Tue 8/2512:14 am
BOG
- JAX
1 stop9h 31m
United Airlines
Deal found 6/1![United Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:00 am
JAX
- BAQ
1 stop5h 34m
American Airlines
Mon 8/31:34 pm
BAQ
- JAX
2 stops17h 55m
American Airlines
Deal found 6/3![American Airlines logo]()
$513
This LATAM Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:46 pm
JAX
- UIO
2 stops10h 12m
LATAM Airlines
Fri 11/137:00 pm
UIO
- JAX
2 stops22h 27m
LATAM Airlines
Deal found 6/4![LATAM Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:30 am
JAX
- BOG
2 stops12h 50m
United Airlines
Tue 8/2512:14 am
BOG
- JAX
3 stops19h 40m
United Airlines
Deal found 6/1![United Airlines logo]()
$565
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
JAX
- BAQ
1 stop9h 38m
American Airlines
Tue 8/41:34 pm
BAQ
- JAX
1 stop19h 31m
American Airlines
Deal found 5/31![American Airlines logo]()
$528
This LATAM Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:05 am
JAX
- LIM
2 stops15h 00m
LATAM Airlines
Mon 8/3112:05 pm
LIM
- JAX
1 stop10h 50m
LATAM Airlines
Deal found 6/4![LATAM Airlines logo]()
$751
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am
JAX
- BOG
2 stops21h 55m
United Airlines
Tue 9/1512:14 am
BOG
- JAX
3 stops19h 40m
United Airlines
Deal found 6/1![United Airlines logo]()
$565
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:05 am
JAX
- LIM
2 stops14h 15m
Delta
Mon 8/3112:05 pm
LIM
- JAX
1 stop20h 32m
Delta
Deal found 6/3![Delta logo]()
$755
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:03 am
JAX
- BOG
2 stops11h 14m
American Airlines
Wed 8/266:30 am
BOG
- JAX
2 stops13h 16m
American Airlines
Deal found 6/1![American Airlines logo]()
$565
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
JAX
- LIM
2 stops15h 20m
Delta
Mon 8/178:15 am
LIM
- JAX
2 stops14h 40m
Delta
Deal found 6/1![Delta logo]()
$760
Last-minute flights from Jacksonville to South AmericaDiscover last-minute flight deals from Jacksonville to South America. Data last updated June 5, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to South America. Data last updated June 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:28 pm
JAX
- CTG
1 stop20h 45m
American Airlines
Sat 7/41:35 pm
CTG
- JAX
1 stop18h 52m
American Airlines
Deal found 6/3![American Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/218:20 am
JAX
- CTG
2 stops16h 15m
Delta
Sat 7/42:30 pm
CTG
- JAX
1 stop8h 29m
Delta
Deal found 5/31![Delta logo]()
$475
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:11 pm
JAX
- CTG
2 stops19h 24m
American Airlines
Fri 7/103:17 pm
CTG
- JAX
2 stops20h 33m
American Airlines
Deal found 6/3![American Airlines logo]()
$459
This JetBlue deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 7/2212:35 pm
CTG
- JAX
1 stop6h 26m
JetBlue
Deal found 5/31![JetBlue logo]()
$455
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:37 pm
JAX
- BAQ
1 stop20h 01m
American Airlines
Mon 7/201:34 pm
BAQ
- JAX
1 stop18h 53m
American Airlines
Deal found 6/1![American Airlines logo]()
$472
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:35 pm
JAX
- MDE
2 stops27h 35m
United Airlines
Wed 7/229:45 am
MDE
- JAX
2 stops35h 14m
United Airlines
Deal found 6/2![United Airlines logo]()
$345
This JetBlue deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 7/2212:35 pm
CTG
- JAX
1 stop6h 26m
JetBlue
Deal found 5/31![JetBlue logo]()
$429
This KAYAK deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:35 pm
JAX
- MDE
2 stops27h 35m
Multiple Airlines
Wed 7/229:45 am
MDE
- JAX
1 stop12h 35m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$436
This JetBlue deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Mon 7/2712:35 pm
CTG
- JAX
1 stop6h 26m
JetBlue
Deal found 6/5![JetBlue logo]()
$443
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 7/2912:35 pm
CTG
- JAX
1 stop6h 26m
JetBlue
Deal found 6/4![JetBlue logo]()
$458
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:00 am
JAX
- BAQ
1 stop5h 34m
American Airlines
Mon 8/31:34 pm
BAQ
- JAX
2 stops17h 55m
American Airlines
Deal found 6/3![American Airlines logo]()
$513
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:17 pm
JAX
- CTG
2 stops19h 00m
American Airlines
Tue 8/43:17 pm
CTG
- JAX
1 stop7h 58m
American Airlines
Deal found 5/31![American Airlines logo]()
$477
One-way flights from Jacksonville to South AmericaSearch for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated June 5, 2026.
Search for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated June 5, 2026.
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:58 pm
JAX
- MDE
1 stop5h 41m
American Airlines
Deal found 6/2![American Airlines logo]()
$133
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:49 am
JAX
- MDE
2 stops38h 16m
United Airlines
Deal found 6/2![United Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:44 am
JAX
- MDE
2 stops13h 51m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:44 am
JAX
- MDE
2 stops24h 36m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:20 am
JAX
- LIM
2 stops14h 30m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:06 pm
JAX
- BOG
3 stops46h 09m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$271
This BusinessClass deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:37 pm
JAX
- CTG
1 stop19h 40m
GOL
Deal found 6/2![GOL logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:49 am
JAX
- UIO
2 stops15h 26m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:44 am
JAX
- MDE
2 stops13h 51m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$282
This Avianca deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:05 am
JAX
- BOG
1 stop12h 05m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$283
This Avianca deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:10 am
JAX
- BOG
1 stop7h 15m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$286
This Avianca deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:05 am
JAX
- BOG
1 stop7h 20m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$293
Find flight deals from Jacksonville to South America
Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated June 5, 2026.
Round-trip from | $326 (KAYAK) |
|---|---|
One-way from | $133 (American Airlines) |
Popular in | July |
Cheapest in | April |
Average price | $623 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Mon 9/14
7:05 am-9:10 pm
1 stop15h 05m
Medellín Jose Maria Cordova Intl
Thu 9/17
9:45 am-11:20 pm
1 stop12h 35m
$327
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Thu 9/17
7:05 am-9:10 pm
1 stop15h 05m
Medellín Jose Maria Cordova Intl
Mon 9/21
9:45 am-10:51 am
2 stops48h 06m
$345
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Mon 10/19
8:26 pm-12:05 pm
2 stops16h 39m
Cartagena Rafael Nunez
Mon 10/26
2:05 pm-10:16 am
2 stops19h 11m
$378
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Fri 8/21
11:20 am-2:15 pm
2 stops27h 55m
Medellín Jose Maria Cordova Intl
Wed 8/26
6:25 am-10:25 am
2 stops27h 00m
$411
Quickest round-trip
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sat 7/18
7:10 am-11:35 am
1 stop5h 25m
Cartagena Rafael Nunez
Wed 7/22
12:35 pm-8:01 pm
1 stop6h 26m
$429
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Mon 7/20
7:10 am-11:35 am
1 stop5h 25m
Cartagena Rafael Nunez
Mon 7/27
12:35 pm-8:01 pm
1 stop6h 26m
$443
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Fri 7/3
6:11 pm-12:35 pm
2 stops19h 24m
Cartagena Rafael Nunez
Fri 7/10
3:17 pm-12:50 pm
2 stops20h 33m
$459
JacksonvilleBarranquilla
JAX - BAQ
JAXBAQ
Jacksonville
Fri 7/17
7:37 pm-2:38 pm
1 stop20h 01m
Barranquilla E Cortissoz
Mon 7/20
1:34 pm-9:27 am
1 stop18h 53m
$472
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sun 6/21
8:20 am-11:35 pm
2 stops16h 15m
Cartagena Rafael Nunez
Sat 7/4
2:30 pm-11:59 pm
1 stop8h 29m
$475
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Wed 7/29
7:37 pm-2:17 pm
1 stop19h 40m
Cartagena Rafael Nunez
Tue 8/4
3:17 pm-12:15 am
1 stop7h 58m
$479
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
JAX-MDE
JAX-CTG
JAX-UIO
JAX-BOG
JAX-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to South America
JAX-0SA
JAX-MDE
JAX-CTG
JAX-UIO
JAX-BOG
What is the cheapest month to book a flight from Jacksonville to South America?
Currently, February is the cheapest month in which you can book a flight from Jacksonville to South America (average of $154). Flying from Jacksonville to South America in September is currently the most expensive (average of $507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Jacksonville to South America?
To ensure you get the cheapest price possible for a flight from Jacksonville to South America, you should look to book at least 70 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 5, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.9
Food
7.2
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.9
Food
7.2
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.9
Food
7.2
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.9
Food
7.2
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.9
Food
7.2
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Jacksonville to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to South America by cabin class
Find flights from Jacksonville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and South America flights
Browse other Jacksonville and South America flight options. Last updated on June 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Jacksonville to South America flights
Consider these flights traveling from Jacksonville to South America.
Top 4 airlines flying from Jacksonville to South America
Discover the top 4 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$154 | Average$367 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$407 | Average$888 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$408 | Average$828 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$590 | Average$687 | FlexibilityNo cancel fee | On-time81% |