South America

$220+ Cheap flights from Charleston (CHS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Jul 6 — Jul 131
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Cheap flight deals from Charleston to South America

Cheapest flights from Charleston to South America
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 6, 2026.

This Avianca deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:00 am
CHS
-
UIO
2 stops13h 40m
Multiple Airlines
Tue 11/175:20 pm
UIO
-
CHS
1 stop16h 39m
Multiple Airlines
Deal found 6/4$454
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:13 pm
CHS
-
CTG
1 stop19h 04m
American Airlines
Tue 7/283:17 pm
CTG
-
CHS
2 stops20h 02m
American Airlines
Deal found 6/4$472
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:13 pm
CHS
-
CTG
1 stop17h 22m
American Airlines
Fri 7/103:17 pm
CTG
-
CHS
1 stop18h 05m
American Airlines
Deal found 6/3$519
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:13 pm
CHS
-
CTG
1 stop17h 22m
American Airlines
Thu 7/93:17 pm
CTG
-
CHS
1 stop27h 16m
American Airlines
Deal found 6/5$521
This Justfly.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:05 pm
CHS
-
CTG
1 stop17h 25m
JetBlue
Fri 9/1812:35 pm
CTG
-
CHS
1 stop28h 34m
JetBlue
Deal found 6/5$526
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
CHS
-
CTG
1 stop9h 17m
American Airlines
Sun 8/23:17 pm
CTG
-
CHS
2 stops20h 12m
American Airlines
Deal found 6/3$527
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:50 pm
CHS
-
CTG
2 stops17h 45m
American Airlines
Fri 7/243:17 pm
CTG
-
CHS
1 stop18h 05m
American Airlines
Deal found 6/3$531
This Despegar deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:29 pm
CHS
-
CTG
1 stop20h 31m
JetBlue
Thu 7/912:35 pm
CTG
-
CHS
1 stop28h 15m
JetBlue
Deal found 6/2$534
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:04 am
CHS
-
CTG
1 stop26h 31m
American Airlines
Sat 8/13:17 pm
CTG
-
CHS
2 stops17h 50m
American Airlines
Deal found 6/1$535
This Avianca deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:58 pm
CHS
-
BOG
1 stop13h 32m
Multiple Airlines
Fri 9/188:15 pm
BOG
-
CHS
2 stops13h 00m
Multiple Airlines
Deal found 6/5$536
This Avianca deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:50 am
CHS
-
BOG
2 stops15h 00m
Multiple Airlines
Sun 11/158:35 pm
BOG
-
CHS
2 stops13h 24m
Multiple Airlines
Deal found 6/2$547
This Avianca deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:14 pm
CHS
-
MDE
1 stop13h 56m
Multiple Airlines
Sun 9/138:00 pm
MDE
-
CHS
1 stop13h 15m
Multiple Airlines
Deal found 6/5$559

Find flight deals from Charleston to South America

Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated June 6, 2026.

Round-trip from

$454
(Avianca)

One-way from

$220
(oojo)

Popular in

May

Cheapest in

September

Average price

$699
From Charleston to South America
One-way flight from Charleston to South America
Highest demand for flights based on searches. 19% potential increase in price ($158 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonQuito

CHS - UIO

CHSUIO

Charleston

Tue 9/1

11:00 am-1:15 am

2 stops15h 15m

Quito Mariscal Sucr

Tue 11/17

5:00 pm-9:59 am

2 stops16h 59m

$487

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Fri 7/17

7:50 pm-2:17 pm

2 stops19h 27m

Cartagena Rafael Nunez

Fri 7/24

3:17 pm-10:22 am

1 stop18h 05m

$531

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Fri 7/3

6:44 pm-1:15 pm

1 stop19h 31m

Cartagena Rafael Nunez

Thu 7/9

2:30 pm-12:26 am

1 stop8h 56m

$544

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Wed 7/29

11:04 am-2:17 pm

1 stop28h 13m

Cartagena Rafael Nunez

Mon 8/3

3:17 pm-12:29 pm

2 stops20h 12m

$562

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Fri 7/24

7:50 pm-12:35 pm

2 stops17h 45m

Cartagena Rafael Nunez

Tue 7/28

3:17 pm-12:29 pm

2 stops20h 12m

$574

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Fri 7/24

8:13 pm-2:17 pm

1 stop19h 04m

Cartagena Rafael Nunez

Sat 8/1

1:35 pm-11:59 pm

1 stop9h 24m

$578

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Mon 7/27

6:50 am-7:20 pm

1 stop13h 30m

Bogotá El Dorado

Wed 8/5

7:20 am-11:52 pm

1 stop15h 32m

$585

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Mon 7/27

7:59 pm-11:10 pm

2 stops28h 11m

Bogotá El Dorado

Wed 8/5

2:55 pm-11:58 pm

1 stop8h 03m

$590

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Thu 7/23

6:00 am-2:17 pm

1 stop9h 17m

Cartagena Rafael Nunez

Sun 8/2

3:17 pm-10:22 am

1 stop18h 05m

$590

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Thu 7/9

6:50 am-4:54 am

1 stop23h 04m

Bogotá El Dorado

Thu 7/30

11:10 pm-11:52 pm

1 stop23h 42m

$596

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/5

Showing 1-10 of 58 resultsSorted by cheapest first
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Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, September is the cheapest month in which you can book a flight from Charleston to South America (average of $156). Flying from Charleston to South America in May is currently the most expensive (average of $699). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 6, 2026.
See what other customers who have flown with Delta,LATAM Airlines, andAmerican Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Boarding

8.1

Crew

8.5

Comfort

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Entertainment

7.8

Boarding

8.1

Crew

8.5

Comfort

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Entertainment

7.8

Boarding

8.1

Crew

8.5

Comfort

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Entertainment

7.8

Boarding

8.1

Crew

8.5

Comfort

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to South America?

    Airlines like American Airlines, Delta, and United Airlines fly from Charleston to South America in about 13h 30m. The time it takes to get you to your destination can typically vary by up to 6h 01m. Charleston and South America are separated by a distance of 1983 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Charleston to South America?

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, September is the cheapest month in which you can book a flight from Charleston to South America (average of $156). Flying from Charleston to South America in May is currently the most expensive (average of $699). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Charleston to South America

Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$301Average$691FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$493Average$730FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$542Average$737FlexibilityNo cancel feeOn-time81%

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