$420+ Cheap flights from San Antonio (SAT) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Santiago
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Best
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Cheapest flights from San Antonio to SantiagoExplore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:04 pm
SAT
- SCL
1 stop11h 46m
American Airlines
Tue 11/1010:15 pm
SCL
- SAT
2 stops23h 35m
American Airlines
Deal found 6/5![American Airlines logo]()
$930
This KAYAK deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:24 pm
SAT
- SCL
1 stop17h 26m
Avianca
Sun 11/810:45 pm
SCL
- SAT
1 stop13h 03m
Avianca
Deal found 6/7![Avianca logo]()
$974
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:04 pm
SAT
- SCL
1 stop11h 46m
American Airlines
Mon 10/199:30 pm
SCL
- SAT
1 stop22h 12m
American Airlines
Deal found 6/7![American Airlines logo]()
$975
This KAYAK deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:20 pm
SAT
- SCL
1 stop13h 30m
Multiple Airlines
Sun 11/810:45 pm
SCL
- SAT
2 stops17h 20m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$979
This KAYAK deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:15 pm
SAT
- SCL
3 stops20h 34m
LATAM Airlines
Tue 11/106:45 pm
SCL
- SAT
2 stops19h 41m
LATAM Airlines
Deal found 6/5![LATAM Airlines logo]()
$1,005
This FlightHub deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:43 pm
SAT
- SCL
1 stop15h 32m
LATAM Airlines
Mon 9/288:40 pm
SCL
- SAT
1 stop23h 58m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$1,015
This Orbitz deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:10 pm
SAT
- SCL
1 stop15h 30m
LATAM Airlines
Sun 11/812:25 am
SCL
- SAT
2 stops27h 03m
LATAM Airlines
Deal found 6/7![LATAM Airlines logo]()
$1,021
This FlightHub deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:10 pm
SAT
- SCL
2 stops14h 45m
LATAM Airlines
Mon 10/1911:00 pm
SCL
- SAT
2 stops23h 22m
LATAM Airlines
Deal found 6/7![LATAM Airlines logo]()
$1,026
Best flights from San Antonio to SantiagoDiscover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:35 pm
SAT
- SCL
2 stops16h 15m
United Airlines
Sun 11/810:45 pm
SCL
- SAT
2 stops20h 45m
United Airlines
Deal found 6/7![United Airlines logo]()
$980
This FlightHub deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:46 am
SAT
- SCL
2 stops16h 39m
LATAM Airlines
Mon 9/288:40 pm
SCL
- SAT
1 stop23h 58m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$1,015
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:30 am
SAT
- SCL
2 stops22h 30m
Delta
Mon 10/197:55 pm
SCL
- SAT
2 stops26h 27m
Delta
Deal found 6/5![Delta logo]()
$1,055
This Mytrip deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:56 pm
SAT
- SCL
3 stops28h 39m
Multiple Airlines
Sun 7/123:20 pm
SCL
- SAT
3 stops29h 47m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$1,233
This KAYAK deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:10 pm
SAT
- SCL
3 stops21h 15m
LATAM Airlines
Mon 10/194:50 pm
SCL
- SAT
2 stops20h 36m
LATAM Airlines
Deal found 6/7![LATAM Airlines logo]()
$1,060
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:19 pm
SAT
- SCL
2 stops18h 46m
Delta
Mon 7/137:55 pm
SCL
- SAT
2 stops20h 15m
Delta
Deal found 6/5![Delta logo]()
$1,165
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:30 am
SAT
- SCL
1 stop22h 20m
United Airlines
Mon 12/710:45 pm
SCL
- SAT
1 stop13h 03m
United Airlines
Deal found 6/7![United Airlines logo]()
$1,245
Last-minute flights from San Antonio to SantiagoDiscover last-minute flight deals from San Antonio to Santiago. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Santiago. Data last updated June 8, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:32 pm
SAT
- SCL
3 stops28h 03m
Multiple Airlines
Tue 6/233:20 pm
SCL
- SAT
2 stops29h 15m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$975
This Cheapflightsfares deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:47 am
SAT
- SCL
1 stop19h 28m
LATAM Airlines
Mon 7/138:40 pm
SCL
- SAT
1 stop15h 29m
LATAM Airlines
Deal found 6/7![LATAM Airlines logo]()
$1,161
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:19 pm
SAT
- SCL
2 stops18h 46m
Delta
Mon 7/137:55 pm
SCL
- SAT
2 stops20h 15m
Delta
Deal found 6/5![Delta logo]()
$1,165
This Mytrip deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:56 pm
SAT
- SCL
2 stops25h 24m
Multiple Airlines
Sun 7/123:20 pm
SCL
- SAT
2 stops29h 15m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$1,167
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/69:37 am
SAT
- SCL
2 stops18h 37m
Copa Airlines
Mon 7/134:21 am
SCL
- SAT
2 stops19h 21m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$1,207
This eDestinos deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:38 am
SAT
- SCL
1 stop19h 37m
LATAM Airlines
Tue 7/2811:05 pm
SCL
- SAT
2 stops22h 32m
LATAM Airlines
Deal found 6/6![LATAM Airlines logo]()
$1,157
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:30 am
SAT
- SCL
2 stops20h 30m
Copa Airlines
Fri 8/72:14 am
SCL
- SAT
2 stops31h 13m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$1,174
One-way flights from San Antonio to SantiagoSearch for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:51 pm
SAT
- SCL
3 stops33h 09m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$420
This Trip.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:56 pm
SAT
- SCL
2 stops30h 49m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:01 am
SAT
- SCL
1 stop25h 04m
American Airlines
Deal found 6/5![American Airlines logo]()
$674
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/264:15 pm
SAT
- SCL
1 stop14h 00m
LATAM Airlines
Deal found 6/3![LATAM Airlines logo]()
$734
Find flight deals from San Antonio to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $930 (American Airlines) |
One-way from | $420 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $1,328 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Mon 10/26
1:35 pm-7:50 am
2 stops16h 15m
Santiago Arturo Merino Benitez
Sun 11/8
10:45 pm-4:30 pm
2 stops20h 45m
$980
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Mon 9/7
10:46 am-5:25 am
2 stops16h 39m
Santiago Arturo Merino Benitez
Mon 9/28
8:40 pm-6:38 pm
1 stop23h 58m
$1,015
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Fri 10/9
5:30 am-6:00 am
2 stops22h 30m
Santiago Arturo Merino Benitez
Mon 10/19
7:55 pm-8:22 pm
2 stops26h 27m
$1,055
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Fri 10/9
2:10 pm-1:25 pm
3 stops21h 15m
Santiago Arturo Merino Benitez
Mon 10/19
4:50 pm-11:26 am
2 stops20h 36m
$1,060
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Mon 7/6
6:19 pm-2:05 pm
2 stops18h 46m
Santiago Arturo Merino Benitez
Mon 7/13
7:55 pm-3:10 pm
2 stops20h 15m
$1,165
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Mon 7/6
8:56 pm-2:35 am
3 stops28h 39m
Santiago Arturo Merino Benitez
Sun 7/12
3:20 pm-8:07 pm
3 stops29h 47m
$1,233
Quickest round-trip
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Thu 12/3
7:30 am-8:50 am
1 stop22h 20m
Santiago Arturo Merino Benitez
Mon 12/7
10:45 pm-8:48 am
1 stop13h 03m
$1,245
Cheapest one-way
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Wed 6/24
7:51 pm-6:00 am
3 stops33h 09m
$420
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Fri 6/26
8:56 pm-4:45 am
2 stops30h 49m
$639
Quickest one-way
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Fri 6/26
4:15 pm-7:15 am
1 stop14h 00m
$734
Sorted by cheapest first
Compare providers for flights from San Antonio to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
SAT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Santiago
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 8, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Antonio to Santiago
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Complete your trip
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San Antonio and Santiago flights
Browse other San Antonio and Santiago flight options. Last updated on June 8, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on June 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 8, 2026.
Top 3 airlines flying from San Antonio to Santiago
Discover the top 3 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$566 | Average$875 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$778 | Average$1,275 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$783 | Average$1,116 | FlexibilityNo cancel fee | On-time71% |