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$212+ Cheap flights from Columbia, MO to Santa Ana, CA (COU - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/29. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SNA
Jul 8 — Jul 151
Wed 7/8
Wed 7/15
1 adult, Economy
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Cheap flight deals from Columbia to Santa Ana

Cheapest flights from Columbia to Santa Ana
Explore the most affordable flight options available from Columbia to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.

This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:46 am
COU
-
SNA
1 stop7h 43m
American Airlines
Tue 8/252:29 pm
SNA
-
COU
1 stop5h 58m
American Airlines
Deal found 6/4$318
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:46 am
COU
-
SNA
1 stop7h 43m
American Airlines
Mon 8/316:45 am
SNA
-
COU
1 stop8h 02m
American Airlines
Deal found 6/5$379
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:55 am
COU
-
SNA
1 stop9h 56m
United Airlines
Tue 8/256:32 pm
SNA
-
COU
2 stops13h 44m
United Airlines
Deal found 6/4$414
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:16 pm
COU
-
SNA
1 stop8h 44m
United Airlines
Sat 10/311:20 pm
SNA
-
COU
1 stop5h 10m
United Airlines
Deal found 6/7$418
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:45 am
COU
-
SNA
1 stop5h 51m
American Airlines
Tue 7/2111:31 am
SNA
-
COU
1 stop7h 30m
American Airlines
Deal found 6/4$439
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:55 am
COU
-
SNA
2 stops11h 56m
United Airlines
Mon 8/312:25 pm
SNA
-
COU
1 stop6h 30m
United Airlines
Deal found 6/5$442
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
COU
-
SNA
1 stop8h 30m
American Airlines
Sun 8/2311:20 am
SNA
-
COU
1 stop8h 00m
American Airlines
Deal found 6/5$451

Find flight deals from Columbia to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$318
(American Airlines)

One-way from

$212
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$472
Provider with most accurate pricing for Columbia Regional-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Columbia Regional to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Columbia Regional to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($106 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($83 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Columbia to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

11:46 am-5:29 pm

1 stop7h 43m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

9:07 am-4:47 pm

1 stop5h 40m

$328

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

10:55 am-6:51 pm

1 stop9h 56m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

6:32 pm-10:16 am

2 stops13h 44m

$414

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

10:55 am-5:29 pm

2 stops8h 34m

Santa Ana J. Wayne/Orange Cnty

Mon 8/31

7:59 pm-10:16 am

2 stops12h 17m

$479

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 7/11

11:45 am-5:37 pm

1 stop7h 52m

Santa Ana J. Wayne/Orange Cnty

Sat 7/18

6:46 am-4:49 pm

1 stop8h 03m

$513

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 6/24

3:25 pm-10:32 pm

1 stop9h 07m

Santa Ana J. Wayne/Orange Cnty

Mon 6/29

2:10 pm-11:33 pm

1 stop7h 23m

$553

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 6/23

9:14 am-2:56 pm

1 stop7h 42m

Santa Ana J. Wayne/Orange Cnty

Sat 6/27

10:20 am-8:39 pm

1 stop8h 19m

$553
Cheapest one-way

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 7/11

9:39 am-8:53 am

3 stops49h 14m

$302

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 7/11

9:39 am-2:51 pm

2 stops31h 12m

$307

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 6/17

11:44 am-12:34 pm

3 stops50h 50m

$309

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 7/11

9:14 am-2:56 pm

1 stop7h 42m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/7

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Compare providers for flights from Columbia to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to Santa Ana in June.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbia, Missouri-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbia, Missouri-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbia to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated June 8, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to Santa Ana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,781 reviews

Entertainment

7.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,781 reviews
United Airlines
7.4
Good
9,781 reviews

Entertainment

7.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.1
Good
11,640 reviews
United Airlines
7.4
Good
9,781 reviews

Entertainment

7.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to Santa Ana, California?

    There are many flights that can get you from Columbia, Missouri to Santa Ana, California in 7h 43m. Fly via American Airlines or United Airlines to get the fastest option. The distance from Columbia, Missouri to Santa Ana, California is about 1466 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Columbia, Missouri to Santa Ana, California round-trip?

    Our cheapest airline available from Columbia, Missouri to Santa Ana, California is United Airlines. Our recent data shows that you can find tickets from as low as $383 on this airline. An additional option worth looking into is American Airlines, starting at $437. You may be able to fly from Columbia, Missouri to Santa Ana, California for 40% less than the average price by searching for these airlines.

  • Can I find deals for flights from Columbia to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Columbia to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Santa Ana.

  • Can I find deals for business class flights from Columbia to Santa Ana?

    Yes. Cheapflights offers flight deals from Columbia to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Columbia to Santa Ana

Discover the top 2 airlines that operate flights from Columbia to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$383Average$464FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$437Average$566FlexibilityNo cancel feeOn-time71%

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