HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news

Cheap flights from St. Louis (STL) to Panama from $213

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
STL — PTY
May 11 — May 181
From?
To?
Sat 5/11
Sat 5/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

What is the cheapest month to fly from St. Louis to Panama?

The best pricing can be found in the month of October. Prices to Panama from St. Louis average $544. You can even find prices in October for less than $544, as users have found deals to Panama from as low as $349. The month of December appears to be one of the more expensive times to travel to Panama from St. Louis. Flying in the targeted month can save you up to 82%.

When is the cheapest time to fly from St. Louis to Panama (STL - PA)?

When flying from St. Louis to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Cheap United Airlines flights from St. Louis to Panama

Explore cheap flight options specifically provided by United Airlines for the route between St. Louis and Panama. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,689,106 searches. Data last updated May 6, 2024.
Check out some of the cheapest United Airlines flights we've come across from St. Louis to Panama. Make sure to double check the flight details before booking.
Thu 8/16:20 amSTL - PTY
1 stop7h 59mUnited Airlines
Wed 8/283:40 pmPTY - STL
1 stop18h 11mUnited Airlines
Deal found 5/6$460
Mon 5/205:25 pmSTL - PTY
2 stops20h 54mUnited Airlines
Mon 5/277:55 amPTY - STL
1 stop14h 20mUnited Airlines
Deal found 5/6$494
Sun 6/238:55 amSTL - PTY
1 stop29h 24mUnited Airlines
Sun 6/3010:00 amPTY - STL
1 stop12h 14mUnited Airlines
Deal found 5/5$499
Fri 6/286:20 amSTL - PTY
1 stop9h 46mUnited Airlines
Thu 7/43:40 pmPTY - STL
2 stops18h 45mUnited Airlines
Deal found 5/6$524
Sat 5/186:19 amSTL - PTY
1 stop12h 18mUnited Airlines
Sat 5/2510:55 pmPTY - STL
2 stops16h 46mUnited Airlines
Deal found 5/5$534
Tue 7/96:20 amSTL - PTY
1 stop12h 17mUnited Airlines
Wed 7/317:55 amPTY - STL
1 stop14h 22mUnited Airlines
Deal found 5/5$575
Wed 6/266:15 amSTL - PTY
1 stop12h 22mUnited Airlines
Wed 7/103:40 pmPTY - STL
2 stops18h 45mUnited Airlines
Deal found 5/5$579
Mon 5/206:19 amSTL - PTY
1 stop12h 18mUnited Airlines
Mon 5/277:55 amPTY - STL
1 stop25h 58mUnited Airlines
Deal found 5/6$582
Sun 6/235:31 pmSTL - PTY
2 stops22h 35mUnited Airlines
Sun 6/3010:55 pmPTY - STL
2 stops15h 23mUnited Airlines
Deal found 5/5$599

Cheap American Airlines flights from St. Louis to Panama

Explore cheap flight options specifically provided by American Airlines for the route between St. Louis and Panama. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,689,106 searches. Data last updated May 6, 2024.
Some of the lowest-priced American Airlines flights we've found at this time heading from St. Louis to Panama. If these deals don't fit your criteria, make sure to check back soon as new deals are always added.
Wed 9/255:31 amSTL - PTY
1 stop7h 02mAmerican Airlines
Wed 10/91:55 pmPTY - STL
1 stop9h 05mAmerican Airlines
Deal found 5/5$450
Wed 9/252:03 pmSTL - PTY
2 stops22h 30mAmerican Airlines
Wed 10/91:55 pmPTY - STL
2 stops20h 20mAmerican Airlines
Deal found 5/5$454
Thu 8/16:09 pmSTL - PTY
2 stops19h 58mAmerican Airlines
Wed 8/281:46 pmPTY - STL
2 stops19h 15mAmerican Airlines
Deal found 5/6$474
Wed 6/266:08 pmSTL - PTY
2 stops20h 12mAmerican Airlines
Wed 7/101:20 pmPTY - STL
2 stops19h 46mAmerican Airlines
Deal found 5/5$514
Fri 6/285:38 pmSTL - PTY
2 stops18h 51mAmerican Airlines
Thu 7/43:10 pmPTY - STL
2 stops19h 12mAmerican Airlines
Deal found 5/6$553
Sat 9/76:58 pmSTL - PTY
2 stops17h 35mAmerican Airlines
Wed 9/111:55 pmPTY - STL
2 stops20h 09mAmerican Airlines
Deal found 5/4$601

Cheap St. Louis to Panama flights in May & June 2024

Find cheap flight options from St. Louis to Panama specifically for the months of May and June 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,689,106 searches. Prices were last updated on May 6, 2024.
Scroll through some of the best deals on flights from St. Louis to Panama in 2024. More deals are always being added, so be sure to check back regularly.
Wed 6/266:15 amSTL - PTY
1 stop12h 22mUnited Airlines
Wed 7/107:55 amPTY - STL
1 stop8h 33mUnited Airlines
Deal found 5/5$450
Fri 6/287:15 amSTL - PTY
1 stop12h 41mDelta
Thu 7/42:17 pmPTY - STL
1 stop9h 25mDelta
Deal found 5/6$470
Sat 6/295:30 pmSTL - PTY
2 stops20h 49mUnited Airlines
Thu 7/47:55 amPTY - STL
1 stop8h 33mUnited Airlines
Deal found 5/6$474
Mon 5/205:25 pmSTL - PTY
2 stops20h 54mUnited Airlines
Mon 5/277:55 amPTY - STL
1 stop14h 20mUnited Airlines
Deal found 5/6$494
Sun 6/238:55 amSTL - PTY
1 stop29h 24mUnited Airlines
Sun 6/3010:00 amPTY - STL
1 stop12h 14mUnited Airlines
Deal found 5/5$499
Wed 6/266:08 pmSTL - PTY
2 stops20h 12mAmerican Airlines
Wed 7/101:20 pmPTY - STL
2 stops19h 46mAmerican Airlines
Deal found 5/5$514
Fri 6/286:20 amSTL - PTY
1 stop9h 46mUnited Airlines
Thu 7/43:40 pmPTY - STL
2 stops18h 45mUnited Airlines
Deal found 5/6$524
Mon 5/205:25 pmSTL - PTY
2 stops20h 54mUnited Airlines
Mon 5/2710:55 pmPTY - STL
2 stops15h 19mUnited Airlines
Deal found 5/6$534
Fri 6/285:38 pmSTL - PTY
2 stops18h 51mAmerican Airlines
Thu 7/43:10 pmPTY - STL
2 stops19h 12mAmerican Airlines
Deal found 5/6$553

St. Louis to Panama 2024 flight deals

Discover exclusive flight deals for travel between St. Louis and Panama in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,689,106 searches. Data last updated May 6, 2024.
Scroll through some of the best deals on flights from St. Louis to Panama in 2024. More deals are always being added, so be sure to check back regularly.
Wed 6/266:15 amSTL - PTY
1 stop12h 22mUnited Airlines
Wed 7/107:55 amPTY - STL
1 stop8h 33mUnited Airlines
Deal found 5/5$450
Wed 9/252:03 pmSTL - PTY
2 stops22h 30mAmerican Airlines
Wed 10/91:55 pmPTY - STL
2 stops20h 20mAmerican Airlines
Deal found 5/6$454
Thu 8/16:20 amSTL - PTY
1 stop12h 17mUnited Airlines
Wed 8/283:40 pmPTY - STL
2 stops18h 27mUnited Airlines
Deal found 5/6$464
Thu 8/16:20 amSTL - PTY
1 stop7h 59mUnited Airlines
Wed 8/283:40 pmPTY - STL
1 stop24h 42mUnited Airlines
Deal found 5/6$468
Fri 6/287:15 amSTL - PTY
1 stop12h 41mDelta
Thu 7/42:17 pmPTY - STL
1 stop9h 25mDelta
Deal found 5/6$470
Thu 8/16:09 pmSTL - PTY
2 stops20h 11mAmerican Airlines
Wed 8/281:46 pmPTY - STL
2 stops18h 41mAmerican Airlines
Deal found 5/6$474
Sat 9/76:00 amSTL - PTY
1 stop6h 55mDelta
Wed 9/112:20 pmPTY - STL
1 stop9h 15mDelta
Deal found 5/6$480
Sat 9/78:05 amSTL - PTY
2 stops10h 32mUnited Airlines
Wed 9/1110:00 amPTY - STL
1 stop12h 13mUnited Airlines
Deal found 5/6$484
Sat 7/67:15 amSTL - PTY
1 stop12h 41mDelta
Sat 7/138:15 amPTY - STL
1 stop8h 05mDelta
Deal found 5/6$490

One-way flights to Panama from St. Louis

Search for one-way flight options from St. Louis to Panama. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,689,106 searches. Data last updated May 6, 2024.
Users traveling one-way from St. Louis to Panama can select one of these great deals. Users can also find round-trip St. Louis to Panama flights by using the search form above.
Wed 5/298:05 amSTL - PTY
2 stops10h 32mUnited Airlines
Deal found 5/5$213
Sun 5/126:00 amSTL - PTY
1 stop6h 48mDelta
Deal found 5/5$233
Thu 5/306:19 pmSTL - PTY
3 stops26h 26mMultiple Airlines
Deal found 5/5$238
Sun 6/306:08 pmSTL - PTY
2 stops20h 12mAmerican Airlines
Deal found 5/5$258
Sun 5/127:30 pmSTL - PTY
3 stops43h 15mMultiple Airlines
Deal found 5/5$278
Sun 6/306:55 pmSTL - PTY
3 stops25h 50mMultiple Airlines
Deal found 5/5$351

Find flights from St. Louis to Panama within your budget

Customize your flight search to find flights from St. Louis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,689,106 searches. Data last updated May 6, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$450 - $501

Route

Depart

Return

Price

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Wed 9/25

1 stop7h 02m

Panama City Tocumen Intl

Wed 10/9

1 stop9h 05m

$450

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Wed 9/25

2 stops22h 30m

Panama City Tocumen Intl

Wed 10/9

2 stops20h 20m

$454

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Thu 8/1

1 stop7h 59m

Panama City Tocumen Intl

Wed 8/28

1 stop18h 11m

$460

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sat 9/7

1 stop6h 55m

Panama City Tocumen Intl

Wed 9/11

1 stop9h 15m

$470

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Thu 8/1

2 stops19h 58m

Panama City Tocumen Intl

Wed 8/28

2 stops19h 15m

$474

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sat 8/3

1 stop9h 48m

Panama City Tocumen Intl

Sat 8/10

1 stop15h 24m

$490

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Mon 5/20

2 stops20h 54m

Panama City Tocumen Intl

Mon 5/27

1 stop14h 20m

$494

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sun 6/23

1 stop29h 24m

Panama City Tocumen Intl

Sun 6/30

1 stop12h 14m

$499

Lambert-St LouisPanama City Tocumen Intl

STL - PTY

STLPTY

Lambert-St Louis

Sat 5/18

3 stops27h 30m

Panama City Tocumen Intl

Sat 5/25

3 stops23h 45m

$501

Flights are sorted by cheapest first

Deals found on 5/5

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 6, 2024.
Read through reviews of airlines operating flights from St. Louis to Panama, such as United Airlines, American Airlines and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.1
Very good
10,818 reviews
Check prices

Crew

8.6

Entertainment

8.0

Comfort

7.9

Overall

8.1

Food

7.4

Boarding

8.2

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Delta
8.1
Very good
10,818 reviews
Delta
8.1
Very good
10,818 reviews
Check prices

Crew

8.6

Entertainment

8.0

Comfort

7.9

Overall

8.1

Food

7.4

Boarding

8.2

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

United Airlines
7.4
Good
11,090 reviews
Delta
8.1
Very good
10,818 reviews
Check prices

Crew

8.6

Entertainment

8.0

Comfort

7.9

Overall

8.1

Food

7.4

Boarding

8.2

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

American Airlines
7.3
Good
14,697 reviews
Delta
8.1
Very good
10,818 reviews
Check prices

Crew

8.6

Entertainment

8.0

Comfort

7.9

Overall

8.1

Food

7.4

Boarding

8.2

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Panama?

    For a flight from St. Louis to Panama, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • Can I find flights from St. Louis to Panama for under $500 on Cheapflights?

    Yes, there are multiple flights from St. Louis to Panama for under $500. The cheapest flight booked recently is on American Airlines for just $450, but on average you can expect to pay $532.

  • What are the cheapest airlines to fly from St. Louis to Panama one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $213. Delta flights start at $233 while deals on American Airlines start at $258 one-way.

  • What are the most popular airlines that fly from St. Louis to Panama?

    When booking a flight from St. Louis to Panama, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

  • What does STL to PTY mean?

    Lambert-St Louis Airport is STL and Panama City Tocumen Intl Airport is PTY. These codes are created by the International Air Transport Association (IATA) and airlines use them to identify the departing and arrival airports in the flight routes they service. Panama City Marcos A. Gelabert Intl Airport (PAC), David Enrique Malek Airport (DAV), Bocas Del Toro Airport (BOC), Panama City Panamá Pacifico Airport (BLB), Pedasí Capt. J. Montenegro Airport (PDM) are other airports near this flight route and their unique identifiers/IATA codes.

  • Can I find deals for flights from St. Louis to Panama that include extra baggage allowance?

    The amount of baggage you can bring on your St. Louis to Panama flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from St. Louis to Panama with specific airlines?

    Yes, Cheapflights allows you to browse and filter St. Louis to Panama flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from St. Louis to Panama that include hotel bookings?

    Yes. In addition to deals on St. Louis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Panama.

  • Can I find deals for business class flights from St. Louis to Panama?

    Yes. Cheapflights offers flight deals from St. Louis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from St. Louis to Panama that allow pets onboard?

    Many airlines flying from St. Louis to Panama offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from St. Louis to Panama?

    Yes, you can often find last-minute deals on St. Louis to Panama flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the St. Louis to Panama flight deals updated?

    The St. Louis to Panama flight deals you see on this page were last updated on 5/6.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Panama
See prices for flight routes from nearby airports that may be better suited for you.

Kansas City to San José flights
Kansas City to Panama City flights
St. Louis to San José flights
Kansas City to Philip S.W.Goldson flights
St. Louis to Panama City flights
St. Louis to Liberia flights
Kansas City to Guatemala City flights
St. Louis to Philip S.W.Goldson flights
Kansas City to San Salvador flights
St. Louis to San Pedro Sula flights
Kansas City to Liberia flights
Kansas City to Coxen Hole flights
Springfield to Philip S.W.Goldson flights
St. Louis to Guatemala City flights
St. Louis to Managua flights
Kansas City to Managua flights
Springfield to Panama City flights
Springfield to Guatemala City flights
Springfield to San José flights
Kansas City to San Pedro Sula flights
St. Louis to Coxen Hole flights
Springfield to Coxen Hole flights
Columbia to Liberia flights
St. Louis to Tegucigalpa flights
Kansas City to Tegucigalpa flights

Top 3 airlines flying from St. Louis to Panama

Discover the top 3 airlines that operate flights from St. Louis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,689,106 searches. Data last updated May 6, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$509FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
United AirlinesCheapest$349Average$419FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
American AirlinesCheapest$356Average$542FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
USA to Georgia flights
Chicago to Minneapolis flights
Dallas to Paris flights
Atlanta to New Orleans flights
Nashville to Miami flights
Chicago to London flights
Los Angeles to Italy flights
Boston to Austin flights
New York to Cancún flights
New York to Montreal flights
Austin to New Orleans flights
St. Louis to Panama City Beach flights

Search flights from St. Louis to Panama by cabin class

Find flights from St. Louis to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
First Class
Business Class
Prem Econ Class
Economy Class

Book a flight to one of these trending destinations

User searches for flights to these destinations increased 20% or more in the past 90 days compared to other destinations
Flights to Saint Peter Jersey
Flights to Kirkwall Arpt
Flights to Skiathos
Flights to Naxos
Flights to Ningbo Lishe Intl
Flights to Edremit/Korfez
Flights to Bourgas
Flights to Bodø
Flights to Pellston Emmet County
Flights to Cornwall Newquay
Flights to Ordu/Giresun
Flights to Batumi
Flights to Mason City
Flights to Biarritz Parme
Flights to Zakynthos Dionsios Salomos
Flights to Cortez Montezuma County
Flights to Clermont-Ferrand Aulnat
Flights to Nevsehir
Flights to Hyannis Barnstable
Flights to Girona Costa Brava
Flights to Kagoshima
Flights to Perugia Sant Egidio
Flights to Oran Es Senia
Flights to Chios

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from St. Louis to Panama?

Cheapflights helps you search for flights from St. Louis to Panama via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from St. Louis to Panama?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama from St. Louis.

Can Cheapflights find flights from St. Louis to Panama with no change fees?

Yes, we can. To see specific flights from St. Louis to Panama with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from St. Louis to Panama become cheaper?

Not ready to book yet? You can track prices for flights from St. Louis to Panama on Cheapflights with our Price Alert feature and get notified when better prices are available.

100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
View all available airlines