$171+ Cheap flights from Knoxville to Manchester, NH (TYS - MHT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MHT
Jul 8 — Jul 151
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Manchester with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Manchester
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to ManchesterExplore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:10 am
TYS
- MHT
1 stop4h 15m
Southwest
Sun 7/1211:30 am
MHT
- TYS
2 stops9h 50m
Southwest
Deal found 6/3![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:35 pm
TYS
- MHT
1 stop5h 27m
United Airlines
Fri 7/107:37 pm
MHT
- TYS
1 stop4h 17m
United Airlines
Deal found 6/3![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:25 am
TYS
- MHT
1 stop9h 20m
Southwest
Sun 8/236:05 am
MHT
- TYS
2 stops8h 55m
Southwest
Deal found 6/5![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:00 am
TYS
- MHT
2 stops8h 05m
Southwest
Fri 7/105:10 pm
MHT
- TYS
1 stop5h 25m
Southwest
Deal found 6/3![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:45 pm
TYS
- MHT
2 stops10h 05m
Southwest
Tue 7/145:45 am
MHT
- TYS
2 stops11h 15m
Southwest
Deal found 6/7![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:30 pm
TYS
- MHT
1 stop9h 20m
Southwest
Fri 10/29:10 am
MHT
- TYS
2 stops7h 35m
Southwest
Deal found 6/6![Southwest logo]()
$388
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:10 am
TYS
- MHT
2 stops8h 05m
Southwest
Wed 7/83:55 pm
MHT
- TYS
1 stop5h 25m
Southwest
Deal found 6/3![Southwest logo]()
$395
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:03 pm
TYS
- MHT
1 stop4h 36m
American Airlines
Wed 7/812:07 pm
MHT
- TYS
1 stop6h 13m
American Airlines
Deal found 6/3![American Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:30 pm
TYS
- MHT
2 stops9h 55m
Southwest
Mon 10/55:25 am
MHT
- TYS
2 stops11h 20m
Southwest
Deal found 6/6![Southwest logo]()
$407
Best flights from Knoxville to ManchesterDiscover carefully curated flight deals from Knoxville to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from Knoxville to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:10 am
TYS
- MHT
1 stop4h 15m
Southwest
Sun 7/1211:30 am
MHT
- TYS
2 stops9h 50m
Southwest
Deal found 6/3![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:35 pm
TYS
- MHT
1 stop5h 27m
United Airlines
Fri 7/107:37 pm
MHT
- TYS
1 stop4h 17m
United Airlines
Deal found 6/3![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:03 pm
TYS
- MHT
1 stop4h 36m
American Airlines
Wed 7/812:07 pm
MHT
- TYS
1 stop6h 13m
American Airlines
Deal found 6/3![American Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:25 am
TYS
- MHT
1 stop9h 20m
Southwest
Sun 8/236:05 am
MHT
- TYS
2 stops8h 55m
Southwest
Deal found 6/5![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:45 am
TYS
- MHT
1 stop4h 23m
United Airlines
Wed 8/262:46 pm
MHT
- TYS
1 stop5h 38m
United Airlines
Deal found 6/5![United Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:00 am
TYS
- MHT
2 stops8h 05m
Southwest
Fri 7/105:10 pm
MHT
- TYS
1 stop5h 25m
Southwest
Deal found 6/3![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:45 pm
TYS
- MHT
2 stops10h 05m
Southwest
Tue 7/143:55 pm
MHT
- TYS
1 stop5h 25m
Southwest
Deal found 6/7![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:10 am
TYS
- MHT
2 stops8h 05m
Southwest
Wed 7/83:55 pm
MHT
- TYS
1 stop5h 25m
Southwest
Deal found 6/3![Southwest logo]()
$395
Last-minute flights from Knoxville to ManchesterDiscover last-minute flight deals from Knoxville to Manchester. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Manchester. Data last updated June 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:03 pm
TYS
- MHT
1 stop4h 36m
American Airlines
Sat 6/135:38 am
MHT
- TYS
1 stop6h 48m
American Airlines
Deal found 6/3![American Airlines logo]()
$487
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:10 am
TYS
- MHT
2 stops8h 05m
Southwest
Wed 7/83:55 pm
MHT
- TYS
1 stop5h 25m
Southwest
Deal found 6/3![Southwest logo]()
$395
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:03 pm
TYS
- MHT
1 stop4h 36m
American Airlines
Wed 7/812:07 pm
MHT
- TYS
1 stop6h 13m
American Airlines
Deal found 6/3![American Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:35 pm
TYS
- MHT
1 stop5h 27m
United Airlines
Fri 7/107:37 pm
MHT
- TYS
1 stop4h 17m
United Airlines
Deal found 6/3![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:00 am
TYS
- MHT
2 stops8h 05m
Southwest
Fri 7/105:10 pm
MHT
- TYS
1 stop5h 25m
Southwest
Deal found 6/3![Southwest logo]()
$382
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:00 am
TYS
- MHT
1 stop4h 07m
American Airlines
Sun 7/126:00 am
MHT
- TYS
1 stop5h 27m
American Airlines
Deal found 6/7![American Airlines logo]()
$451
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:45 pm
TYS
- MHT
2 stops10h 05m
Southwest
Tue 7/145:45 am
MHT
- TYS
2 stops11h 15m
Southwest
Deal found 6/7![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:10 am
TYS
- MHT
1 stop4h 15m
Southwest
Sun 7/1211:30 am
MHT
- TYS
2 stops9h 50m
Southwest
Deal found 6/3![Southwest logo]()
$369
One-way flights from Knoxville to ManchesterSearch for one-way flight options from Knoxville to Manchester. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from Knoxville to Manchester. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:10 am
TYS
- MHT
2 stops8h 05m
Southwest
Deal found 6/4![Southwest logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:20 pm
TYS
- MHT
2 stops16h 29m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$185
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:42 am
TYS
- MHT
2 stops8h 19m
United Airlines
Deal found 6/5![United Airlines logo]()
$256
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:19 pm
TYS
- MHT
1 stop4h 40m
United Airlines
Deal found 6/7![United Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/291:35 pm
TYS
- MHT
1 stop5h 27m
United Airlines
Deal found 6/5![United Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/291:05 pm
TYS
- MHT
3 stops22h 40m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/291:35 pm
TYS
- MHT
1 stop5h 27m
United Airlines
Deal found 6/8![United Airlines logo]()
$646
Find flight deals from Knoxville to Manchester
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $369 (Southwest) |
One-way from | $171 (Southwest) |
Popular in | April |
Cheapest in | June |
Average price | $323 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Wed 7/8
8:10 am-12:25 pm
1 stop4h 15m
Manchester
Sun 7/12
11:30 am-9:20 pm
2 stops9h 50m
$369
Quickest round-trip
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Sat 7/4
1:35 pm-7:02 pm
1 stop5h 27m
Manchester
Fri 7/10
7:37 pm-11:54 pm
1 stop4h 17m
$377
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Mon 8/17
8:25 am-5:45 pm
1 stop9h 20m
Manchester
Sun 8/23
6:05 am-3:00 pm
2 stops8h 55m
$379
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Sat 7/4
7:00 am-3:05 pm
2 stops8h 05m
Manchester
Fri 7/10
5:10 pm-10:35 pm
1 stop5h 25m
$382
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Tue 7/7
12:45 pm-10:50 pm
2 stops10h 05m
Manchester
Tue 7/14
3:55 pm-9:20 pm
1 stop5h 25m
$382
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Wed 7/1
8:10 am-4:15 pm
2 stops8h 05m
Manchester
Wed 7/8
3:55 pm-9:20 pm
1 stop5h 25m
$395
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Wed 7/1
7:03 pm-11:39 pm
1 stop4h 36m
Manchester
Wed 7/8
12:07 pm-6:20 pm
1 stop6h 13m
$404
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Tue 8/25
9:45 am-2:08 pm
1 stop4h 23m
Manchester
Wed 8/26
2:46 pm-8:24 pm
1 stop5h 38m
$411
Cheapest one-way
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Wed 7/29
8:10 am-4:15 pm
2 stops8h 05m
$171
KnoxvilleManchester
TYS - MHT
TYSMHT
Knoxville McGhee Tyson
Fri 7/3
7:20 pm-11:49 am
2 stops16h 29m
$185
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Manchester
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Manchester in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Manchester, New Hampshire flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Manchester, New Hampshire flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Manchester, New Hampshire flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Manchester, New Hampshire flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Manchester, New Hampshire flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Manchester
Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
TYS-MHT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Manchester
What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?
Currently, February is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $329). Flying from Knoxville to Manchester, New Hampshire in April is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Manchester, New Hampshire?
Reviews of airlines servicing Manchester
Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated June 8, 2026.
Read through reviews of airlines operating flights from Knoxville to Manchester, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Entertainment
6.9
Overall
7.1
Boarding
7.5
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Food
6.4
Entertainment
6.9
Overall
7.1
Boarding
7.5
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Manchester?
Book flights to Manchester if you plan to visit one of these locationsKeene
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Manchester flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Manchester
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Manchester by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Manchester by cabin class
Find flights from Knoxville to Manchester, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Manchester
Explore flights to Manchester departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 8, 2026.
Knoxville and Manchester flights
Browse other Knoxville and Manchester flight options. Last updated on June 8, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on June 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Knoxville to Manchester
Discover the top airline that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$393 | FlexibilityNo cancel fee | On-time71% |