$125+ Cheap flights from Missouri to Greenville (GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — GSP
Jul 12 — Jul 191
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to GreenvilleExplore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:43 am
STL
- GSP
1 stop4h 43m
American Airlines
Tue 7/285:28 pm
GSP
- STL
1 stop7h 30m
American Airlines
Deal found 6/10![American Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:07 pm
MCI
- GSP
2 stops24h 49m
Multiple Airlines
Thu 7/163:46 pm
GSP
- MCI
1 stop19h 04m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:18 pm
MCI
- GSP
1 stop4h 41m
Delta
Tue 8/2510:04 am
GSP
- MCI
1 stop4h 48m
Delta
Deal found 6/9![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/223:10 pm
STL
- GSP
1 stop5h 55m
Southwest
Tue 7/287:00 am
GSP
- STL
2 stops7h 05m
Southwest
Deal found 6/10![Southwest logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:57 pm
MCI
- GSP
1 stop18h 28m
Multiple Airlines
Fri 8/216:19 pm
GSP
- MCI
2 stops24h 05m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:57 pm
MCI
- GSP
1 stop18h 28m
Multiple Airlines
Thu 8/203:43 pm
GSP
- MCI
2 stops50h 41m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$285
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:15 pm
MCI
- GSP
1 stop3h 40m
Southwest
Sat 8/2212:55 pm
GSP
- MCI
1 stop7h 35m
Southwest
Deal found 6/9![Southwest logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:09 pm
MCI
- GSP
1 stop18h 14m
Multiple Airlines
Mon 8/244:40 pm
GSP
- MCI
2 stops49h 44m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$293
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:01 am
STL
- GSP
1 stop5h 02m
American Airlines
Mon 9/287:41 pm
GSP
- STL
1 stop4h 01m
American Airlines
Deal found 6/9![American Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:57 pm
MCI
- GSP
1 stop18h 28m
Multiple Airlines
Tue 8/2511:07 am
GSP
- MCI
2 stops31h 17m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:57 pm
MCI
- GSP
1 stop18h 28m
Multiple Airlines
Sun 8/233:43 pm
GSP
- MCI
2 stops26h 41m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:58 pm
MCI
- GSP
1 stop4h 34m
Delta
Thu 8/208:49 am
GSP
- MCI
1 stop4h 37m
Delta
Deal found 6/9![Delta logo]()
$301
Best flights from Missouri to GreenvilleDiscover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from Missouri to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:40 am
STL
- GSP
2 stops8h 55m
Southwest
Mon 9/284:40 pm
GSP
- STL
2 stops6h 25m
Southwest
Deal found 6/9![Southwest logo]()
$313
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:00 am
MCI
- GSP
1 stop6h 02m
United Airlines
Wed 8/266:30 am
GSP
- MCI
1 stop6h 50m
United Airlines
Deal found 6/11![United Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:43 am
MCI
- GSP
1 stop5h 58m
Delta
Tue 8/2510:04 am
GSP
- MCI
1 stop4h 48m
Delta
Deal found 6/9![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:10 pm
STL
- GSP
1 stop5h 55m
Southwest
Fri 7/246:50 pm
GSP
- STL
1 stop5h 00m
Southwest
Deal found 6/10![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:00 am
MCI
- GSP
1 stop6h 02m
United Airlines
Wed 8/126:30 am
GSP
- MCI
1 stop4h 55m
United Airlines
Deal found 6/8![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:15 pm
STL
- GSP
2 stops7h 40m
Southwest
Tue 7/287:00 am
GSP
- STL
2 stops7h 05m
Southwest
Deal found 6/10![Southwest logo]()
$345
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:08 am
STL
- GSP
1 stop5h 53m
Delta
Sun 7/195:44 am
GSP
- STL
1 stop3h 35m
Delta
Deal found 6/8![Delta logo]()
$403
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
STL
- GSP
1 stop4h 32m
United Airlines
Wed 8/267:00 am
GSP
- STL
2 stops9h 38m
United Airlines
Deal found 6/10![United Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:15 am
MCI
- GSP
2 stops7h 35m
Southwest
Fri 7/106:50 pm
GSP
- MCI
1 stop6h 25m
Southwest
Deal found 6/7![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:30 am
SGF
- GSP
1 stop5h 02m
United Airlines
Tue 9/110:33 am
GSP
- SGF
1 stop4h 55m
United Airlines
Deal found 6/9![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:50 am
STL
- GSP
1 stop6h 25m
Southwest
Sun 7/267:30 pm
GSP
- STL
1 stop5h 25m
Southwest
Deal found 6/7![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:27 pm
STL
- GSP
1 stop6h 18m
United Airlines
Wed 8/127:00 am
GSP
- STL
2 stops9h 38m
United Airlines
Deal found 6/8![United Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:20 am
MCI
- GSP
2 stops6h 50m
Southwest
Wed 7/87:40 pm
GSP
- MCI
1 stop4h 50m
Southwest
Deal found 6/11![Southwest logo]()
$389
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:10 pm
MCI
- GSP
1 stop5h 55m
United Airlines
Sun 8/166:30 am
GSP
- MCI
1 stop4h 55m
United Airlines
Deal found 6/7![United Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:10 pm
MCI
- GSP
2 stops7h 40m
Southwest
Sun 7/57:30 pm
GSP
- MCI
1 stop5h 45m
Southwest
Deal found 6/8![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:35 pm
STL
- GSP
1 stop4h 20m
Southwest
Thu 7/167:05 am
GSP
- STL
2 stops6h 40m
Southwest
Deal found 6/11![Southwest logo]()
$402
Last-minute flights from Missouri to GreenvilleDiscover last-minute flight deals from Missouri to Greenville. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Greenville. Data last updated June 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:31 am
MCI
- GSP
1 stop4h 39m
American Airlines
Wed 7/87:20 pm
GSP
- MCI
1 stop5h 59m
American Airlines
Deal found 6/11![American Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:20 am
STL
- GSP
1 stop5h 40m
United Airlines
Tue 7/75:43 pm
GSP
- STL
1 stop6h 46m
United Airlines
Deal found 6/8![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:10 pm
MCI
- GSP
1 stop3h 40m
Southwest
Sun 7/57:30 pm
GSP
- MCI
1 stop5h 45m
Southwest
Deal found 6/8![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/42:20 pm
MCI
- GSP
1 stop3h 50m
Southwest
Fri 7/106:50 pm
GSP
- MCI
1 stop6h 25m
Southwest
Deal found 6/7![Southwest logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:07 pm
MCI
- GSP
2 stops24h 49m
Multiple Airlines
Thu 7/163:46 pm
GSP
- MCI
1 stop19h 04m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/812:25 pm
MCI
- GSP
2 stops8h 40m
Southwest
Thu 7/168:30 am
GSP
- MCI
2 stops9h 10m
Southwest
Deal found 6/9![Southwest logo]()
$377
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:55 am
STL
- GSP
1 stop5h 15m
Southwest
Sun 7/197:30 pm
GSP
- STL
1 stop5h 25m
Southwest
Deal found 6/12![Southwest logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:09 pm
STL
- GSP
1 stop14h 26m
Multiple Airlines
Sun 7/198:25 am
GSP
- STL
2 stops25h 32m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:43 am
STL
- GSP
1 stop4h 43m
American Airlines
Tue 7/285:28 pm
GSP
- STL
1 stop7h 30m
American Airlines
Deal found 6/10![American Airlines logo]()
$267
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/223:10 pm
STL
- GSP
1 stop5h 55m
Southwest
Tue 7/287:00 am
GSP
- STL
2 stops7h 05m
Southwest
Deal found 6/10![Southwest logo]()
$280
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:15 pm
STL
- GSP
2 stops7h 40m
Southwest
Tue 7/287:00 am
GSP
- STL
2 stops7h 05m
Southwest
Deal found 6/10![Southwest logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:50 pm
SGF
- GSP
1 stop17h 45m
Allegiant Air
Thu 7/303:46 pm
GSP
- SGF
1 stop17h 15m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$384
One-way flights from Missouri to GreenvilleSearch for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
Search for one-way flight options from Missouri to Greenville. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:45 pm
STL
- GSP
1 stop3h 10m
Southwest
Deal found 6/12![Southwest logo]()
$125
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
STL
- GSP
2 stops7h 20m
United Airlines
Deal found 6/12![United Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:07 pm
MCI
- GSP
2 stops36h 21m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:07 pm
MCI
- GSP
2 stops24h 49m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$146
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:04 pm
MCI
- GSP
1 stop5h 47m
American Airlines
Deal found 6/10![American Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:57 pm
STL
- GSP
2 stops21h 09m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$178
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:30 am
MCI
- GSP
1 stop7h 45m
Southwest
Deal found 6/7![Southwest logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
- GSP
3 stops35h 54m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$200
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/58:05 am
STL
- GSP
1 stop3h 05m
Southwest
Deal found 6/11![Southwest logo]()
$204
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:10 pm
MCI
- GSP
2 stops9h 55m
United Airlines
Deal found 6/7![United Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
MCI
- GSP
1 stop7h 04m
American Airlines
Deal found 6/8![American Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:34 pm
STL
- GSP
3 stops43h 32m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$217
Find flight deals from Missouri to Greenville
Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated June 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $267 (American Airlines) |
One-way from | $143 (Kiwi.com) |
Popular in | February |
Cheapest in | October |
Average price | $364 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Mon 9/21
11:40 am-9:35 pm
2 stops8h 55m
Greenville
Mon 9/28
4:40 pm-10:05 pm
2 stops6h 25m
$313
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 7/21
3:10 pm-10:05 pm
1 stop5h 55m
Greenville
Fri 7/24
6:50 pm-10:50 pm
1 stop5h 00m
$327
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Tue 8/25
10:00 am-5:02 pm
1 stop6h 02m
Greenville
Wed 8/26
6:30 am-12:20 pm
1 stop6h 50m
$345
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Tue 8/11
10:00 am-5:02 pm
1 stop6h 02m
Greenville
Wed 8/12
6:30 am-10:25 am
1 stop4h 55m
$345
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Fri 7/24
2:15 pm-10:55 pm
2 stops7h 40m
Greenville
Tue 7/28
7:00 am-1:05 pm
2 stops7h 05m
$345
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Thu 8/6
5:43 am-12:41 pm
1 stop5h 58m
Greenville
Tue 8/25
10:04 am-1:52 pm
1 stop4h 48m
$348
Kansas CityGreenville
MCI - GSP
MCIGSP
Kansas City
Sat 7/4
7:15 am-3:50 pm
2 stops7h 35m
Greenville
Fri 7/10
6:50 pm-12:15 am
1 stop6h 25m
$372
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Tue 8/25
8:00 am-1:32 pm
1 stop4h 32m
Greenville
Wed 8/26
7:00 am-3:38 pm
2 stops9h 38m
$373
St. LouisGreenville
STL - GSP
STLGSP
Lambert-St Louis
Fri 7/24
5:50 am-1:15 pm
1 stop6h 25m
Greenville
Sun 7/26
7:30 pm-11:55 pm
1 stop5h 25m
$387
SpringfieldGreenville
SGF - GSP
SGFGSP
Springfield-Branson
Sat 8/29
7:30 am-1:32 pm
1 stop5h 02m
Greenville
Tue 9/1
10:33 am-2:28 pm
1 stop4h 55m
$389
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from Missouri to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
STL-GSP
MCI-GSP
SGF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Greenville
USMO-GSP
STL-GSP
MCI-GSP
SGF-GSP
What is the cheapest month to book a flight from Missouri to Greenville?
Currently, August is the cheapest month in which you can book a flight from Missouri to Greenville (average of $172). Flying from Missouri to Greenville in July is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Greenville?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
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Alternative routes for Missouri to Greenville
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Complete your trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Missouri and Greenville flights
Browse other Missouri and Greenville flight options. Last updated on June 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Greenville flights
Consider these flights traveling from Missouri to Greenville.
Top 3 airlines flying from Missouri to Greenville
Discover the top 3 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$361 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$415 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$431 | FlexibilityNo cancel fee | On-time63% |