HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Grand Cayman

$631+ Cheap flights from Knoxville (TYS) to Grand Cayman

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GCM
Jul 12 — Jul 191
Sun 7/12
Sun 7/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Grand Cayman with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Grand Cayman

Cheapest flights from Knoxville to Grand Cayman
Explore the most affordable flight options available from Knoxville to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.

This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am
TYS
-
GCM
1 stop5h 00m
American Airlines
Tue 9/2212:00 pm
GCM
-
TYS
1 stop8h 58m
American Airlines
Deal found 6/9$631
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
TYS
-
GCM
1 stop6h 31m
Delta
Wed 8/121:04 pm
GCM
-
TYS
1 stop9h 50m
Delta
Deal found 6/12$656
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:05 pm
TYS
-
GCM
1 stop16h 20m
American Airlines
Tue 7/215:10 pm
GCM
-
TYS
1 stop5h 49m
American Airlines
Deal found 6/11$666
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:35 am
TYS
-
GCM
1 stop4h 56m
Delta
Fri 7/3112:56 pm
GCM
-
TYS
1 stop9h 56m
Delta
Deal found 6/9$681
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:00 am
TYS
-
GCM
1 stop11h 10m
American Airlines
Sat 8/14:07 pm
GCM
-
TYS
1 stop6h 52m
American Airlines
Deal found 6/11$694
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:00 am
TYS
-
GCM
1 stop6h 00m
American Airlines
Fri 7/315:10 pm
GCM
-
TYS
2 stops16h 41m
American Airlines
Deal found 6/11$699
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am
TYS
-
GCM
1 stop8h 10m
American Airlines
Mon 9/72:10 pm
GCM
-
TYS
1 stop8h 41m
American Airlines
Deal found 6/11$701

Find flight deals from Knoxville to Grand Cayman

Keep the following information in mind while searching for Knoxville to Grand Cayman flight deals. Data was last updated June 12, 2026.

Round-trip from

$631
(American Airlines)

Popular in

May

Cheapest in

February

Average price

$596
From Knoxville McGhee Tyson to Grand Cayman
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($124 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($38 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Knoxville to Grand Cayman that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Sat 8/1

6:00 am-11:31 am

1 stop6h 31m

George Town Owen Roberts Intl

Wed 8/12

1:04 pm-11:54 pm

1 stop9h 50m

$656

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Thu 7/16

5:40 am-11:31 am

1 stop6h 51m

George Town Owen Roberts Intl

Tue 7/21

12:56 pm-11:52 pm

1 stop9h 56m

$661

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Sat 8/1

8:56 am-3:03 pm

1 stop7h 07m

George Town Owen Roberts Intl

Wed 8/12

2:10 pm-9:43 am

2 stops18h 33m

$671

KnoxvilleGeorge Town

TYS - GCM

TYSGCM

Knoxville McGhee Tyson

Thu 7/16

8:05 pm-11:00 am

2 stops15h 55m

George Town Owen Roberts Intl

Tue 7/21

12:02 pm-11:59 pm

1 stop10h 57m

$671

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Sorted by cheapest first

Best time to book a flight from Knoxville to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Grand Cayman
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated June 12, 2026.
Get a feel of what it's like to fly with American Airlines from Knoxville to Grand Cayman by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,645 reviews

Overall

7.1

Entertainment

6.9

Crew

7.9

Boarding

7.5

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,645 reviews
American Airlines
7.1
Good
11,645 reviews

Overall

7.1

Entertainment

6.9

Crew

7.9

Boarding

7.5

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Grand Cayman?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Grand Cayman. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Grand Cayman?

    Airlines like Delta fly from Knoxville to Grand Cayman in about 6h 31m. The time it takes to get you to your destination can typically vary by up to . There are 1151 mi between Knoxville and Grand Cayman.

  • Can I find deals for flights from Knoxville to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Knoxville to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Grand Cayman.

  • Can I find deals for business class flights from Knoxville to Grand Cayman?

    Yes. Cheapflights offers flight deals from Knoxville to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Grand Cayman by adding a car rental and/or hotel reservation to your travel itinerary.
George Town Owen Roberts Intl Airport car rentals
George Town car rentals

Top airline flying from Knoxville to Grand Cayman

Discover the top airline that operate flights from Knoxville to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$540Average$655FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.