$125+ Cheap flights from San Antonio to Des Moines (SAT - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — DSM
Jul 10 — Jul 171
Round-trip
1 adult, Economy
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Cheapest flights from San Antonio to Des MoinesExplore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:20 am
SAT
- DSM
1 stop5h 23m
Delta
Tue 8/116:55 am
DSM
- SAT
1 stop4h 54m
Delta
Deal found 6/10![Delta logo]()
$263
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:57 pm
SAT
- DSM
1 stop4h 38m
United Airlines
Tue 8/116:00 am
DSM
- SAT
1 stop5h 52m
United Airlines
Deal found 6/8![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:30 pm
SAT
- DSM
2 stops6h 40m
Southwest
Tue 8/112:40 pm
DSM
- SAT
2 stops8h 15m
Southwest
Deal found 6/8![Southwest logo]()
$328
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:35 am
SAT
- DSM
1 stop7h 40m
United Airlines
Wed 10/76:00 am
DSM
- SAT
1 stop6h 11m
United Airlines
Deal found 6/9![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:30 pm
SAT
- DSM
2 stops8h 25m
Southwest
Tue 8/112:40 pm
DSM
- SAT
2 stops8h 15m
Southwest
Deal found 6/10![Southwest logo]()
$346
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:52 pm
SAT
- DSM
1 stop6h 15m
American Airlines
Tue 7/75:12 am
DSM
- SAT
1 stop4h 56m
American Airlines
Deal found 6/5![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:40 am
SAT
- DSM
1 stop5h 02m
United Airlines
Tue 8/113:20 pm
DSM
- SAT
2 stops7h 19m
United Airlines
Deal found 6/10![United Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:28 am
SAT
- DSM
1 stop5h 57m
American Airlines
Mon 8/104:13 pm
DSM
- SAT
1 stop6h 37m
American Airlines
Deal found 6/9![American Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/202:26 pm
SAT
- DSM
1 stop6h 42m
Delta
Wed 7/2210:54 am
DSM
- SAT
1 stop6h 17m
Delta
Deal found 6/9![Delta logo]()
$381
Best flights from San Antonio to Des MoinesDiscover carefully curated flight deals from San Antonio to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
Discover carefully curated flight deals from San Antonio to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:30 pm
SAT
- DSM
2 stops8h 25m
Southwest
Tue 8/112:40 pm
DSM
- SAT
2 stops8h 15m
Southwest
Deal found 6/10![Southwest logo]()
$346
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:17 pm
SAT
- DSM
2 stops7h 42m
United Airlines
Wed 10/71:27 pm
DSM
- SAT
2 stops9h 24m
United Airlines
Deal found 6/9![United Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:15 pm
SAT
- DSM
1 stop6h 14m
Delta
Mon 7/206:37 pm
DSM
- SAT
1 stop5h 43m
Delta
Deal found 6/9![Delta logo]()
$417
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:40 pm
SAT
- DSM
1 stop8h 05m
Southwest
Fri 7/244:40 pm
DSM
- SAT
1 stop7h 30m
Southwest
Deal found 6/9![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:32 pm
SAT
- DSM
1 stop5h 24m
United Airlines
Wed 7/158:00 am
DSM
- SAT
1 stop8h 29m
United Airlines
Deal found 6/8![United Airlines logo]()
$435
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/291:50 pm
SAT
- DSM
2 stops9h 40m
Southwest
Wed 7/13:45 pm
DSM
- SAT
1 stop7h 55m
Southwest
Deal found 6/5![Southwest logo]()
$396
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:50 pm
SAT
- DSM
2 stops10h 45m
Southwest
Fri 8/712:05 pm
DSM
- SAT
1 stop8h 10m
Southwest
Deal found 6/9![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:20 am
SAT
- DSM
1 stop5h 30m
Southwest
Tue 7/283:45 pm
DSM
- SAT
1 stop8h 00m
Southwest
Deal found 6/7![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:10 pm
SAT
- DSM
1 stop8h 10m
Southwest
Tue 7/73:45 pm
DSM
- SAT
1 stop8h 00m
Southwest
Deal found 6/5![Southwest logo]()
$413
Last-minute flights from San Antonio to Des MoinesDiscover last-minute flight deals from San Antonio to Des Moines. Data last updated June 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Des Moines. Data last updated June 10, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/291:50 pm
SAT
- DSM
2 stops9h 40m
Southwest
Wed 7/13:45 pm
DSM
- SAT
1 stop7h 55m
Southwest
Deal found 6/5![Southwest logo]()
$396
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:52 pm
SAT
- DSM
1 stop6h 15m
American Airlines
Tue 7/75:12 am
DSM
- SAT
1 stop4h 56m
American Airlines
Deal found 6/5![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:10 pm
SAT
- DSM
1 stop8h 10m
Southwest
Tue 7/73:45 pm
DSM
- SAT
1 stop8h 00m
Southwest
Deal found 6/5![Southwest logo]()
$413
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:55 pm
SAT
- DSM
2 stops8h 50m
Southwest
Tue 7/216:25 am
DSM
- SAT
1 stop4h 55m
Southwest
Deal found 6/6![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:20 am
SAT
- DSM
1 stop5h 25m
Delta
Thu 7/162:25 pm
DSM
- SAT
1 stop7h 54m
Delta
Deal found 6/7![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:20 am
SAT
- DSM
1 stop5h 25m
Delta
Wed 7/2210:54 am
DSM
- SAT
1 stop6h 17m
Delta
Deal found 6/9![Delta logo]()
$391
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/202:26 pm
SAT
- DSM
1 stop6h 42m
Delta
Tue 7/212:45 pm
DSM
- SAT
1 stop6h 41m
Delta
Deal found 6/9![Delta logo]()
$381
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:40 pm
SAT
- DSM
1 stop8h 05m
Southwest
Fri 7/244:40 pm
DSM
- SAT
2 stops6h 55m
Southwest
Deal found 6/9![Southwest logo]()
$386
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:05 am
SAT
- DSM
1 stop8h 00m
Delta
Tue 7/216:37 pm
DSM
- SAT
1 stop5h 43m
Delta
Deal found 6/9![Delta logo]()
$387
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:50 pm
SAT
- DSM
2 stops10h 45m
Southwest
Fri 8/712:05 pm
DSM
- SAT
1 stop8h 10m
Southwest
Deal found 6/9![Southwest logo]()
$404
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:47 pm
SAT
- DSM
1 stop6h 22m
American Airlines
Fri 8/74:13 pm
DSM
- SAT
1 stop6h 37m
American Airlines
Deal found 6/9![American Airlines logo]()
$408
One-way flights from San Antonio to Des MoinesSearch for one-way flight options from San Antonio to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
Search for one-way flight options from San Antonio to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
This Mytrip deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:39 pm
SAT
- DSM
1 stop17h 55m
Frontier
Deal found 6/8![Frontier logo]()
$125
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:30 am
SAT
- DSM
1 stop7h 34m
Delta
Deal found 6/8![Delta logo]()
$159
This Booking.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:39 pm
SAT
- DSM
1 stop17h 55m
Frontier
Deal found 6/8![Frontier logo]()
$167
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:55 pm
SAT
- DSM
2 stops8h 50m
Southwest
Deal found 6/8![Southwest logo]()
$183
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:37 am
SAT
- DSM
2 stops11h 45m
United Airlines
Deal found 6/8![United Airlines logo]()
$204
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/299:31 am
SAT
- DSM
1 stop6h 32m
American Airlines
Deal found 6/5![American Airlines logo]()
$214
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/291:50 pm
SAT
- DSM
2 stops9h 40m
Southwest
Deal found 6/5![Southwest logo]()
$219
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:01 am
SAT
- DSM
1 stop4h 10m
American Airlines
Deal found 6/8![American Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:38 pm
SAT
- DSM
3 stops16h 31m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$230
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/612:50 pm
SAT
- DSM
2 stops10h 45m
Southwest
Deal found 6/9![Southwest logo]()
$260
Find flight deals from San Antonio to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $263 (Delta) |
One-way from | $125 (Mytrip) |
Popular in | May |
Cheapest in | September |
Average price | $555 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Wed 8/5
1:30 pm-9:55 pm
2 stops8h 25m
Des Moines
Tue 8/11
2:40 pm-10:55 pm
2 stops8h 15m
$346
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Tue 10/6
4:17 pm-11:59 pm
2 stops7h 42m
Des Moines
Wed 10/7
1:27 pm-10:51 pm
2 stops9h 24m
$353
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Tue 7/21
1:40 pm-9:45 pm
1 stop8h 05m
Des Moines
Fri 7/24
4:40 pm-12:10 am
1 stop7h 30m
$381
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Mon 6/29
1:50 pm-11:30 pm
2 stops9h 40m
Des Moines
Wed 7/1
3:45 pm-11:40 pm
1 stop7h 55m
$396
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Thu 7/30
12:50 pm-11:35 pm
2 stops10h 45m
Des Moines
Fri 8/7
12:05 pm-8:15 pm
1 stop8h 10m
$404
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Sat 7/25
9:20 am-2:50 pm
1 stop5h 30m
Des Moines
Tue 7/28
3:45 pm-11:45 pm
1 stop8h 00m
$407
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Thu 7/2
2:10 pm-10:20 pm
1 stop8h 10m
Des Moines
Tue 7/7
3:45 pm-11:45 pm
1 stop8h 00m
$413
Quickest round-trip
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Fri 7/17
4:15 pm-10:29 pm
1 stop6h 14m
Des Moines
Mon 7/20
6:37 pm-12:20 am
1 stop5h 43m
$417
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Tue 7/14
5:32 pm-10:56 pm
1 stop5h 24m
Des Moines
Wed 7/15
8:00 am-4:29 pm
1 stop8h 29m
$435
Cheapest one-way
San AntonioDes Moines
SAT - DSM
SATDSM
San Antonio
Tue 7/14
7:39 pm-1:34 pm
1 stop17h 55m
$125
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Des Moines in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.
SAT-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Des Moines
What is the cheapest month to book a flight from San Antonio to Des Moines?
Currently, September is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $297). Flying from San Antonio to Des Moines in May is currently the most expensive (average of $667). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 10, 2026.
See what other customers who have flown with United Airlines and American Airlines from San Antonio to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Overall
7.4
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Crew
8.1
Overall
7.4
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Crew
8.1
Overall
7.4
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Food
6.6
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Johnston
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Boone
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Ankeny
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Top 2 airlines flying from San Antonio to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$263 | Average$436 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$412 | FlexibilityNo cancel fee | On-time71% |