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Des Moines

$119+ Cheap flights from North Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
Jul 12 — Jul 191
Sun 7/12
Sun 7/19
1 adult, Economy
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Cheap flight deals from North Carolina to Des Moines

Cheapest flights from North Carolina to Des Moines
Explore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:44 pm
TYS
-
DSM
1 stop6h 48m
Allegiant Air
Thu 7/165:08 pm
DSM
-
TYS
1 stop27h 52m
Allegiant Air
Deal found 6/9$155
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:08 pm
TYS
-
DSM
1 stop29h 07m
Allegiant Air
Thu 7/305:08 pm
DSM
-
TYS
1 stop27h 52m
Allegiant Air
Deal found 6/12$216
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:44 pm
TYS
-
DSM
1 stop6h 48m
Allegiant Air
Sun 7/1210:57 am
DSM
-
TYS
1 stop24h 06m
Allegiant Air
Deal found 6/12$226
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:05 am
RDU
-
DSM
1 stop17h 02m
Multiple Airlines
Mon 7/134:40 pm
DSM
-
RDU
1 stop23h 29m
Multiple Airlines
Deal found 6/9$228
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:05 am
RDU
-
DSM
1 stop17h 02m
Multiple Airlines
Sun 7/123:59 pm
DSM
-
RDU
1 stop5h 44m
Multiple Airlines
Deal found 6/9$236
This Mytrip deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:14 pm
CLT
-
DSM
1 stop19h 17m
Frontier
Wed 8/262:16 pm
DSM
-
CLT
1 stop27h 03m
Frontier
Deal found 6/8$239
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:04 am
TYS
-
DSM
1 stop8h 01m
Allegiant Air
Sun 9/131:58 pm
DSM
-
TYS
1 stop28h 36m
Allegiant Air
Deal found 6/11$243
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:15 am
TYS
-
DSM
2 stops16h 52m
Multiple Airlines
Thu 7/305:08 pm
DSM
-
TYS
1 stop27h 52m
Multiple Airlines
Deal found 6/12$244
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/127:05 am
RDU
-
DSM
1 stop15h 53m
Multiple Airlines
Mon 7/134:40 pm
DSM
-
RDU
1 stop23h 29m
Multiple Airlines
Deal found 6/10$245
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:25 pm
RDU
-
DSM
1 stop4h 30m
Southwest
Wed 8/192:40 pm
DSM
-
RDU
2 stops5h 50m
Southwest
Deal found 6/10$254
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:05 am
RDU
-
DSM
1 stop17h 02m
Multiple Airlines
Thu 7/165:08 pm
DSM
-
RDU
2 stops29h 56m
Multiple Airlines
Deal found 6/10$257
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:00 pm
AVL
-
DSM
1 stop27h 43m
Allegiant Air
Mon 7/134:40 pm
DSM
-
AVL
1 stop16h 50m
Allegiant Air
Deal found 6/10$266

Find flight deals from North Carolina to Des Moines

Keep the following information in mind while searching for North Carolina to Des Moines flight deals. Data was last updated June 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$155
(Kiwi.com)

One-way from

$119
(Kiwi.com)

Popular in

February

Cheapest in

May

Average price

$438

Good round-trip deal

$431 or less
Provider with most accurate pricing for Raleigh-Durham-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Des Moines flights.
Search Deals
From North Carolina to Des Moines
Search Deals
One-way flight from North Carolina to Des Moines
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from North Carolina to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 9/11

9:04 am-4:05 pm

1 stop8h 01m

Des Moines

Sun 9/13

1:58 pm-7:34 pm

1 stop28h 36m

$243

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 7/9

3:44 pm-9:32 pm

1 stop6h 48m

Des Moines

Sun 7/12

10:57 am-12:03 pm

1 stop24h 06m

$269

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 8/12

12:35 pm-9:55 pm

2 stops10h 20m

Des Moines

Wed 8/19

6:10 am-5:55 pm

2 stops10h 45m

$277

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 8/11

6:35 pm-9:55 pm

1 stop4h 20m

Des Moines

Tue 8/18

6:10 am-7:00 pm

2 stops11h 50m

$278

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 7/2

3:38 pm-9:27 pm

1 stop6h 49m

Des Moines

Mon 7/6

4:40 pm-4:10 pm

1 stop22h 30m

$285

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

Wed 9/30

6:30 am-12:04 pm

1 stop6h 34m

Des Moines

Mon 10/5

6:36 pm-11:27 pm

1 stop3h 51m

$290

NorfolkDes Moines

ORF - DSM

ORFDSM

Norfolk

Mon 9/21

2:24 pm-7:15 pm

1 stop5h 51m

Des Moines

Mon 9/28

6:45 pm-12:33 am

1 stop4h 48m

$297

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sat 9/5

6:30 am-2:10 pm

2 stops8h 40m

Des Moines

Tue 9/8

6:10 am-11:55 am

1 stop4h 45m

$299

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 7/9

3:44 pm-9:32 pm

1 stop6h 48m

Des Moines

Sun 7/12

3:59 pm-6:30 pm

2 stops25h 31m

$301

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Tue 7/14

5:12 pm-10:56 pm

1 stop6h 44m

Des Moines

Tue 7/21

3:24 pm-9:37 pm

1 stop5h 13m

$306

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from North Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Des Moines

What is the cheapest month to book a flight from North Carolina to Des Moines?

Currently, April is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $202). Flying from North Carolina to Des Moines in January is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to DSM?

Find hourly flight availability from North Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2026.

It’s typically best to fly out from North Carolina to Des Moines in the morning. Doing so could potentially save you 14% on the flight price compared to flying in the evening, which is usually more expensive.

Weekly flight availability from North Carolina to Des Moines

Explore weekly flight availability from North Carolina to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 12, 2026.

The most flights from USNC to DSM are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from North Carolina to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from North Carolina?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from North Carolina to Des Moines.

  • How popular is this North Carolina to Des Moines flight route?

    This flight path from North Carolina to Des Moines was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from North Carolina to Des Moines?

    A quick flight from North Carolina to Des Moines can take about 5h 51m. Allegiant Air provides one of the quickest options available for as low as $297. Airlines will cover a distance of 985 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Des Moines one-way?

    $92 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $135 and $170, respectively.

  • What are the most popular routes from North Carolina to Des Moines?

    When deciding which route to take from North Carolina to Des Moines consider Charlotte Douglas - Des Moines, Raleigh-Durham - Des Moines or Myrtle Beach Intl - Des Moines as they are the most popular.

  • What are the cheapest flights from North Carolina to Des Moines?

    Looking for the cheapest flight from North Carolina to Des Moines? While on average our users pay $490, our data indicates the cheapest price to be $391. The most popular route (Charlotte Douglas - Des Moines), is priced around $267.

  • Can I find deals for flights from North Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on North Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Des Moines.

  • Can I find deals for business class flights from North Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from North Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $202). Flying from North Carolina to Des Moines in January is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Clive
Boone
West Des Moines
Ankeny

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Top 4 airlines flying from North Carolina to Des Moines

Discover the top 4 airlines that operate flights from North Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$393FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$363FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$377FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$278Average$433FlexibilityNo cancel feeOn-time63%

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