Spain

$249+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Jan 3 — Jan 101
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Cheap flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Justfly.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:50 amSTL - BCN
1 stop14h 10mMultiple Airlines
Thu 12/251:35 pmBCN - STL
2 stops31h 51mMultiple Airlines
Deal found 12/2$411
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:30 amSTL - BCN
1 stop16h 50mUnited Airlines
Thu 12/251:35 pmBCN - STL
2 stops36h 43mUnited Airlines
Deal found 12/2$414
This oojo deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:59 pmMCI - BCN
2 stops16h 31mBritish Airways
Wed 1/1410:40 amBCN - MCI
1 stop19h 32mBritish Airways
Deal found 12/3$422
This KLM deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:35 pmMCI - BCN
1 stop31h 05mKLM
Wed 1/1410:55 amBCN - MCI
1 stop16h 07mKLM
Deal found 12/3$425
This FlightHub deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:50 amSTL - BCN
1 stop14h 10mLufthansa
Thu 12/2511:00 amBCN - STL
1 stop19h 43mLufthansa
Deal found 12/2$430
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amSTL - BCN
1 stop19h 40mDelta
Thu 12/2510:55 amBCN - STL
1 stop19h 43mDelta
Deal found 12/2$434
This FlightHub deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:45 pmMCI - MAD
1 stop12h 20mLufthansa
Tue 12/1611:15 amMAD - MCI
1 stop19h 29mLufthansa
Deal found 12/2$434
This KLM deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:05 amMCI - BCN
1 stop18h 35mKLM
Wed 1/1410:55 amBCN - MCI
1 stop16h 07mKLM
Deal found 12/3$434
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amMCI - MAD
2 stops20h 15mUnited Airlines
Tue 12/1611:15 amMAD - MCI
2 stops17h 43mUnited Airlines
Deal found 12/2$443
This Booking.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/91:40 pmMCI - BCN
1 stop12h 20mBritish Airways
Tue 12/1612:30 pmBCN - MCI
1 stop15h 55mBritish Airways
Deal found 12/2$449
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:05 amMCI - BCN
1 stop18h 35mDelta
Sat 1/1710:15 amBCN - MCI
1 stop31h 58mDelta
Deal found 12/3$450
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:35 pmMCI - BCN
1 stop31h 05mDelta
Fri 1/166:00 amBCN - MCI
2 stops24h 04mDelta
Deal found 12/3$452

Find flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated December 4, 2025.

Round-trip from

$411
(Justfly.com)

One-way from

$249
(Mytrip)

Popular in

June

Cheapest in

February

Average price

$832
From Missouri to Spain
One-way flight from Missouri to Spain
Highest demand for flights based on searches. 24% potential increase in price ($289 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($35 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

SpringfieldBarcelona

SGF - BCN

SGFBCN

Springfield-Branson

Sun 1/18

5:00 pm-5:00 pm

2 stops17h 00m

Barcelona-El Prat

Tue 1/27

10:40 am-7:13 pm

1 stop15h 33m

$422

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Wed 3/4

6:30 am-8:00 am

1 stop18h 30m

Barcelona-El Prat

Tue 3/10

9:15 am-8:44 am

1 stop29h 29m

$425

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Tue 12/30

6:35 pm-8:40 am

1 stop31h 05m

Barcelona-El Prat

Thu 1/15

10:15 am-7:19 pm

1 stop16h 04m

$425

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 1/13

11:34 am-11:55 am

2 stops17h 21m

Madrid Barajas

Tue 1/20

1:15 pm-9:06 pm

1 stop14h 51m

$425

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Wed 12/31

12:38 pm-8:40 am

1 stop13h 02m

Barcelona-El Prat

Fri 1/16

10:55 am-11:06 pm

1 stop19h 11m

$425

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Wed 12/31

7:05 am-8:40 am

1 stop18h 35m

Barcelona-El Prat

Thu 1/15

10:15 am-8:02 pm

2 stops16h 47m

$425

Kansas CityMálaga

MCI - AGP

MCIAGP

Kansas City

Mon 1/26

3:01 pm-4:50 pm

2 stops18h 49m

Malaga

Wed 2/4

5:35 pm-8:43 am

2 stops22h 08m

$429

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Sun 2/1

11:55 am-8:50 am

1 stop13h 55m

Barcelona-El Prat

Tue 2/17

11:00 am-10:05 pm

1 stop18h 05m

$434

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Tue 1/13

7:00 am-8:50 am

1 stop18h 50m

Barcelona-El Prat

Wed 1/21

12:30 pm-9:06 pm

1 stop15h 36m

$434

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 12/9

6:00 am-8:40 am

1 stop19h 40m

Barcelona-El Prat

Thu 12/25

10:55 am-11:38 pm

1 stop19h 43m

$434

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

Showing 1-10 of 57 results
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $451). Flying from Missouri to Spain in May is currently the most expensive (average of $838). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

It’s optimal to fly from Missouri to Spain at noon. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from Missouri to Spain?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Spain. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Spain flight should consider departing on Wednesday mornings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Spain?

    British Airways, Delta, and KLM can get you from Missouri to Spain in just under 17h. Your travel time can differ by up to 14h 05m. There are 4832 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $380. However, be on the lookout for offers from Iberia and United Airlines, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $451). Flying from Missouri to Spain in May is currently the most expensive (average of $838). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Missouri to Spain

Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$433Average$751FlexibilityNo cancel feeOn-time75%
British AirwaysCheapest$483Average$892FlexibilityNo cancel feeOn-time70%
DeltaCheapest$487Average$868FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$498Average$964FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$524Average$1,066FlexibilityNo cancel feeOn-time76%
American AirlinesCheapest$532Average$1,120FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$533Average$752FlexibilityNo cancel feeOn-time77%
IberiaCheapest$578Average$1,011FlexibilityNo cancel feeOn-time77%
Virgin AtlanticCheapest$582Average$707FlexibilityNo cancel feeOn-time72%
Air CanadaCheapest$624Average$1,086FlexibilityNo cancel feeOn-time67%

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