$330+ Cheap flights from Missouri to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
May 31 — Jun 71
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 pm
STL
- MAD
1 stop13h 00m
British Airways
Wed 10/2110:35 am
MAD
- STL
1 stop15h 55m
British Airways
Deal found 4/28![British Airways logo]()
$720
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:59 am
STL
- MAD
1 stop14h 01m
United Airlines
Fri 10/91:30 pm
MAD
- STL
2 stops33h 56m
United Airlines
Deal found 4/27![United Airlines logo]()
$721
This oojo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:35 pm
STL
- MAD
1 stop13h 00m
British Airways
Fri 10/304:40 pm
MAD
- STL
1 stop21h 24m
British Airways
Deal found 4/30![British Airways logo]()
$723
This Gotogate deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:55 am
STL
- VLC
2 stops22h 15m
Multiple Airlines
Fri 10/236:05 am
VLC
- STL
1 stop14h 20m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$724
This Cheapflightsfares deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:35 pm
STL
- VLC
1 stop15h 00m
British Airways
Wed 10/2111:25 am
VLC
- STL
1 stop15h 05m
British Airways
Deal found 4/27![British Airways logo]()
$725
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:40 am
STL
- MAD
2 stops18h 25m
United Airlines
Wed 10/211:30 pm
MAD
- STL
2 stops29h 50m
United Airlines
Deal found 4/28![United Airlines logo]()
$725
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:30 am
STL
- MAD
1 stop19h 45m
United Airlines
Wed 11/116:00 am
MAD
- STL
1 stop14h 55m
United Airlines
Deal found 4/29![United Airlines logo]()
$726
This Gotogate deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:30 pm
STL
- VLC
1 stop19h 00m
Multiple Airlines
Thu 10/225:55 am
VLC
- STL
2 stops19h 46m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$728
This British Airways deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:35 pm
STL
- MAD
1 stop15h 30m
British Airways
Fri 10/93:55 pm
MAD
- STL
1 stop14h 46m
British Airways
Deal found 4/28![British Airways logo]()
$728
This Gotogate deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:30 pm
STL
- VLC
1 stop19h 00m
Multiple Airlines
Wed 10/216:00 am
VLC
- STL
2 stops19h 41m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$730
This oojo deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:35 pm
STL
- VLC
1 stop15h 00m
British Airways
Tue 10/208:30 pm
VLC
- STL
1 stop30h 00m
British Airways
Deal found 4/27![British Airways logo]()
$731
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:23 am
STL
- MAD
2 stops16h 37m
United Airlines
Fri 10/306:00 am
MAD
- STL
1 stop14h 55m
United Airlines
Deal found 4/29![United Airlines logo]()
$731
Best flights from Missouri to SpainDiscover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
MCI
- MAD
1 stop20h 00m
United Airlines
Tue 10/201:30 pm
MAD
- MCI
2 stops31h 38m
United Airlines
Deal found 4/27![United Airlines logo]()
$745
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:26 pm
MCI
- MAD
1 stop11h 49m
Delta
Tue 10/206:00 am
MAD
- MCI
2 stops20h 09m
Delta
Deal found 4/30![Delta logo]()
$812
This Finnair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:28 pm
MCI
- BCN
1 stop14h 42m
Finnair
Sun 9/610:05 am
BCN
- MCI
2 stops21h 31m
Finnair
Deal found 4/28![Finnair logo]()
$940
This KAYAK deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:45 am
MCI
- XRY
2 stops19h 25m
SWISS
Sun 9/2011:00 am
XRY
- MCI
2 stops41h 40m
SWISS
Deal found 4/29![SWISS logo]()
$966
This KLM deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:22 pm
STL
- BCN
1 stop16h 28m
KLM
Mon 8/311:00 am
BCN
- STL
1 stop19h 53m
KLM
Deal found 4/30![KLM logo]()
$1,045
This KLM deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:40 pm
MCI
- BCN
2 stops14h 10m
Multiple Airlines
Mon 7/1310:55 am
BCN
- MCI
1 stop14h 12m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$1,050
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:52 pm
STL
- IBZ
2 stops33h 53m
Iberia
Thu 6/189:40 pm
IBZ
- STL
2 stops33h 19m
Iberia
Deal found 4/26![Iberia logo]()
$1,267
This British Airways deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:33 pm
STL
- BCN
2 stops14h 22m
British Airways
Sat 5/912:50 pm
BCN
- STL
1 stop13h 36m
British Airways
Deal found 4/29![British Airways logo]()
$1,394
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:30 pm
MCI
- VLC
2 stops21h 35m
Lufthansa
Fri 5/296:05 am
VLC
- MCI
2 stops19h 58m
Lufthansa
Deal found 4/30![Lufthansa logo]()
$1,434
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:55 pm
MCI
- MAD
2 stops27h 55m
United Airlines
Fri 10/236:00 am
MAD
- MCI
2 stops23h 34m
United Airlines
Deal found 4/28![United Airlines logo]()
$764
This Air Canada deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:20 am
MCI
- VLC
3 stops17h 50m
Air Canada
Sat 9/266:05 am
VLC
- MCI
3 stops22h 29m
Air Canada
Deal found 4/29![Air Canada logo]()
$1,529
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:16 pm
MCI
- XRY
2 stops32h 29m
American Airlines
Tue 6/99:15 am
XRY
- MCI
2 stops35h 03m
American Airlines
Deal found 4/29![American Airlines logo]()
$1,719
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:58 pm
STL
- MAD
1 stop13h 17m
Delta
Wed 8/512:45 pm
MAD
- STL
1 stop14h 46m
Delta
Deal found 4/29![Delta logo]()
$888
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am
MCI
- MAD
1 stop20h 00m
United Airlines
Fri 9/181:30 pm
MAD
- MCI
2 stops34h 11m
United Airlines
Deal found 4/30![United Airlines logo]()
$823
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:55 pm
MCI
- BCN
2 stops29h 05m
United Airlines
Sat 12/191:35 pm
BCN
- MCI
2 stops33h 44m
United Airlines
Deal found 4/26![United Airlines logo]()
$833
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:04 pm
MCI
- BCN
1 stop17h 46m
Delta
Sat 10/173:15 pm
BCN
- MCI
1 stop25h 17m
Delta
Deal found 4/30![Delta logo]()
$923
This KLM deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/512:25 pm
MCI
- BCN
1 stop17h 25m
KLM
Mon 7/1310:55 am
BCN
- MCI
1 stop14h 12m
KLM
Deal found 4/30![KLM logo]()
$1,045
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
MCI
- BCN
2 stops19h 00m
United Airlines
Tue 9/812:15 pm
BCN
- MCI
2 stops29h 06m
United Airlines
Deal found 4/27![United Airlines logo]()
$854
This KLM deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:36 pm
STL
- VLC
2 stops15h 39m
Multiple Airlines
Tue 6/236:35 am
VLC
- STL
2 stops17h 48m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$1,173
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:22 pm
STL
- MAD
1 stop15h 53m
Delta
Fri 7/2412:45 pm
MAD
- STL
1 stop14h 46m
Delta
Deal found 4/29![Delta logo]()
$980
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:37 pm
MCI
- BCN
1 stop11h 38m
United Airlines
Sat 10/176:00 am
BCN
- MCI
2 stops18h 35m
United Airlines
Deal found 4/27![United Airlines logo]()
$855
This KLM deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:38 pm
MCI
- AGP
2 stops17h 32m
KLM
Tue 5/2610:40 am
AGP
- MCI
2 stops20h 45m
KLM
Deal found 4/28![KLM logo]()
$1,204
This KAYAK deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:14 pm
MCI
- XRY
2 stops35h 56m
SWISS
Sun 9/2011:00 am
XRY
- MCI
2 stops41h 40m
SWISS
Deal found 5/1![SWISS logo]()
$1,372
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:30 am
MCI
- BCN
1 stop18h 45m
United Airlines
Sat 10/1712:15 pm
BCN
- MCI
2 stops29h 18m
United Airlines
Deal found 4/26![United Airlines logo]()
$859
This Justfly.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:05 pm
STL
- MAD
1 stop10h 45m
Multiple Airlines
Wed 6/245:55 am
MAD
- STL
1 stop14h 30m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$1,260
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:51 am
STL
- BCN
1 stop18h 59m
Delta
Mon 8/36:10 am
BCN
- STL
2 stops21h 27m
Delta
Deal found 4/29![Delta logo]()
$1,058
This oojo deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:39 pm
STL
- IBZ
2 stops37h 56m
British Airways
Sat 6/207:45 pm
IBZ
- STL
2 stops35h 14m
British Airways
Deal found 4/28![British Airways logo]()
$1,422
This Finnair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:00 am
STL
- BCN
1 stop19h 00m
Multiple Airlines
Sun 8/27:10 pm
BCN
- STL
1 stop20h 59m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$1,276
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:08 am
MCI
- BCN
2 stops39h 52m
United Airlines
Sun 10/1112:15 pm
BCN
- MCI
2 stops42h 37m
United Airlines
Deal found 4/30![United Airlines logo]()
$883
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:38 am
SGF
- AGP
2 stops24h 02m
Delta
Wed 7/156:00 am
AGP
- SGF
2 stops23h 10m
Delta
Deal found 4/27![Delta logo]()
$1,090
Last-minute flights from Missouri to SpainDiscover last-minute flight deals from Missouri to Spain. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Spain. Data last updated May 1, 2026 and is based on user searches.
This AirNGo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:06 pm
MCI
- MAD
1 stop12h 24m
Finnair
Tue 5/1912:20 pm
MAD
- MCI
1 stop14h 01m
Finnair
Deal found 4/30![Finnair logo]()
$947
This Rumbo deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:22 pm
MCI
- AGP
2 stops17h 28m
SWISS
Tue 5/124:50 pm
AGP
- MCI
2 stops36h 14m
SWISS
Deal found 4/27![SWISS logo]()
$823
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
MCI
- AGP
1 stop18h 35m
United Airlines
Tue 5/129:35 am
AGP
- MCI
1 stop19h 43m
United Airlines
Deal found 4/27![United Airlines logo]()
$837
This Ticket deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:21 pm
STL
- MAD
1 stop13h 09m
Finnair
Wed 5/201:35 pm
MAD
- STL
1 stop15h 44m
Finnair
Deal found 4/30![Finnair logo]()
$897
This Sembo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sembo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:45 am
STL
- MAD
2 stops16h 05m
Multiple Airlines
Wed 5/205:55 am
MAD
- STL
1 stop14h 30m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$938
This Kissandfly.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:25 am
STL
- MAD
2 stops14h 40m
Lufthansa
Wed 5/206:20 am
MAD
- STL
2 stops17h 19m
Lufthansa
Deal found 4/27![Lufthansa logo]()
$949
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:25 am
STL
- MAD
2 stops14h 40m
United Airlines
Wed 5/2010:50 am
MAD
- STL
2 stops17h 28m
United Airlines
Deal found 4/30![United Airlines logo]()
$957
This deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:05 pm
STL
- MAD
1 stop10h 45m
Air Canada
Fri 5/1512:45 pm
MAD
- STL
1 stop14h 40m
Air Canada
Deal found 4/30![Air Canada logo]()
$960
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:15 am
STL
- MAD
1 stop19h 45m
United Airlines
Tue 5/1212:45 pm
MAD
- STL
2 stops32h 47m
United Airlines
Deal found 4/27![United Airlines logo]()
$948
This Gotogate deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:15 pm
STL
- MAD
2 stops33h 35m
Multiple Airlines
Fri 5/226:00 am
MAD
- STL
1 stop14h 25m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$936
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:17 am
MCI
- AGP
2 stops18h 18m
United Airlines
Fri 5/229:35 am
AGP
- MCI
1 stop14h 27m
United Airlines
Deal found 4/29![United Airlines logo]()
$937
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:45 pm
MCI
- AGP
2 stops29h 50m
United Airlines
Wed 6/109:35 am
AGP
- MCI
1 stop21h 24m
United Airlines
Deal found 4/30![United Airlines logo]()
$960
One-way flights from Missouri to SpainSearch for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This oojo deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:18 am
STL
- MAD
2 stops21h 32m
British Airways
Deal found 4/27![British Airways logo]()
$330
This oojo deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am
MCI
- MAD
1 stop14h 30m
British Airways
Deal found 4/27![British Airways logo]()
$352
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:04 pm
MCI
- MAD
2 stops16h 16m
Delta
Deal found 4/27![Delta logo]()
$358
This oojo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:43 pm
MCI
- BCN
2 stops17h 32m
British Airways
Deal found 4/30![British Airways logo]()
$365
This Orbitz deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:51 pm
STL
- VLC
2 stops32h 14m
Iberia
Deal found 4/28![Iberia logo]()
$369
This TravelUp deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:36 pm
MCI
- BCN
1 stop11h 39m
Lufthansa
Deal found 4/28![Lufthansa logo]()
$373
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:45 am
MCI
- BCN
2 stops17h 35m
United Airlines
Deal found 4/28![United Airlines logo]()
$375
This oojo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:49 pm
MCI
- BCN
2 stops32h 51m
British Airways
Deal found 4/30![British Airways logo]()
$376
This Iberia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:13 am
MCI
- BCN
2 stops20h 32m
Iberia
Deal found 4/29![Iberia logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:16 pm
MCI
- BCN
2 stops59h 44m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$400
This Air France deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:45 pm
STL
- VLC
2 stops15h 50m
Air France
Deal found 4/30![Air France logo]()
$405
This Travelocity deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:30 pm
STL
- VLC
1 stop13h 25m
Lufthansa
Deal found 4/30![Lufthansa logo]()
$412
Find flight deals from Missouri to Spain
Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated May 1, 2026.
Round-trip from | $720 (Cheapflightsfares) |
|---|---|
One-way from | $330 (oojo) |
Popular in | June |
Cheapest in | January |
Average price | $921 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/6
6:00 am-9:00 am
1 stop20h 00m
Madrid Barajas
Tue 10/20
1:30 pm-2:08 pm
2 stops31h 38m
$745
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Sat 10/17
7:55 pm-6:50 am
2 stops27h 55m
Madrid Barajas
Fri 10/23
6:00 am-10:34 pm
2 stops23h 34m
$764
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Thu 10/1
5:26 pm-12:15 pm
1 stop11h 49m
Madrid Barajas
Tue 10/20
6:00 am-7:09 pm
2 stops20h 09m
$812
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 9/8
6:00 am-9:00 am
1 stop20h 00m
Madrid Barajas
Fri 9/18
1:30 pm-4:41 pm
2 stops34h 11m
$823
Kansas CityBarcelona
MCI - BCN
MCIBCN
Kansas City
Sat 8/15
7:55 pm-8:00 am
2 stops29h 05m
Barcelona-El Prat
Sat 12/19
1:35 pm-4:19 pm
2 stops33h 44m
$833
Kansas CityBarcelona
MCI - BCN
MCIBCN
Kansas City
Wed 9/2
6:00 am-8:00 am
2 stops19h 00m
Barcelona-El Prat
Tue 9/8
12:15 pm-10:21 am
2 stops29h 06m
$854
Kansas CityBarcelona
MCI - BCN
MCIBCN
Kansas City
Mon 10/5
6:37 pm-1:15 pm
1 stop11h 38m
Barcelona-El Prat
Sat 10/17
6:00 am-5:35 pm
2 stops18h 35m
$855
Kansas CityBarcelona
MCI - BCN
MCIBCN
Kansas City
Sun 10/4
11:30 am-1:15 pm
1 stop18h 45m
Barcelona-El Prat
Sat 10/17
12:15 pm-10:33 am
2 stops29h 18m
$859
Kansas CityBarcelona
MCI - BCN
MCIBCN
Kansas City
Sat 10/3
9:08 am-8:00 am
2 stops39h 52m
Barcelona-El Prat
Sun 10/11
12:15 pm-11:52 pm
2 stops42h 37m
$883
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Wed 7/29
3:58 pm-12:15 pm
1 stop13h 17m
Madrid Barajas
Wed 8/5
12:45 pm-8:31 pm
1 stop14h 46m
$888
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
STL-MAD
MCI-MAD
MCI-BCN
STL-VLC
MCI-AGP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Spain
USMO-ES0
STL-MAD
MCI-MAD
MCI-BCN
STL-VLC
How far ahead should I book a flight from Missouri to Spain?
Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Missouri to Spain?
Currently, March is the cheapest month in which you can book a flight from Missouri to Spain (average of $405). Flying from Missouri to Spain in June is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Top regions
Alternative routes for Missouri to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Spain by cabin class
Find flights from Missouri to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Spain flights
Browse other Missouri and Spain flight options. Last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Spain
Find the right flight back to Missouri after your stay in Spain
Missouri to Spain flights
Consider these flights traveling from Missouri to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 10 airlines flying from Missouri to Spain
Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$433 | Average$741 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$437 | Average$719 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$449 | Average$784 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$457 | Average$753 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$480 | Average$1,104 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$485 | Average$838 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$487 | Average$808 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$488 | Average$782 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$490 | Average$838 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$560 | Average$974 | FlexibilityNo cancel fee | On-time67% |