How long is the flight from Missouri to Spain?

United Airlines, Air Canada, and Scandinavian Airlines can get you from Missouri to Spain in just under 10h 10m. Your travel time can differ by up to 15h 11m. There are 4414 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Missouri to Spain one-way?

The cheapest airline one-way is Scandinavian Airlines, with whom users have recently found tickets for as low as $376. However, be on the lookout for offers from KLM and Delta, as they are both options that can get you from Missouri to Spain for a low price.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Can I find deals for flights from Missouri to Spain that include hotel bookings?

Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Spain?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

Can I find deals for business class flights from Missouri to Spain?

Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$306+ Cheap Flights from Missouri to Spain

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Cheap flight deals from Missouri to Spain

Round-trip from	$417 (Mytrip)
One-way from	$306 (Kiwi.com)
Popular in	June
Cheapest in	February
Average price	$726

From Missouri to Spain

Search Deals

One-way flight from Missouri to Spain

Search Deals

Highest demand for flights based on searches. 32% potential increase in price ($453 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($51 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Mon 10/61:30 pmSTL - MAD

1 stop10h 10mAir Canada

Wed 10/2212:45 pmMAD - STL

2 stops33h 33mAir Canada

Deal found 9/15

$417

Sun 10/121:30 pmSTL - MAD

1 stop10h 10mUnited Airlines

Wed 10/2212:45 pmMAD - STL

2 stops32h 42mUnited Airlines

Deal found 9/16

$418

Wed 12/32:48 pmSTL - MAD

1 stop12h 32mIberia

Mon 12/811:35 amMAD - STL

1 stop14h 31mIberia

Deal found 9/15

$419

Sat 11/16:43 pmSTL - MAD

2 stops31h 17mUnited Airlines

Fri 11/141:35 pmMAD - STL

2 stops33h 11mUnited Airlines

Deal found 9/15

$422

Mon 10/612:25 pmSTL - MAD

2 stops35h 15mUnited Airlines

Wed 10/2212:45 pmMAD - STL

2 stops33h 59mUnited Airlines

Deal found 9/13

$428

Tue 10/79:15 amSTL - MAD

1 stop16h 05mUnited Airlines

Wed 10/2211:15 amMAD - STL

2 stops18h 20mUnited Airlines

Deal found 9/13

$452

Tue 11/119:59 amMCI - BCN

2 stops25h 21mScandinavian Airlines

Sat 11/157:10 pmBCN - MCI

2 stops34h 25mScandinavian Airlines

Deal found 9/14

$499

Mon 9/221:30 pmSTL - BCN

1 stop11h 20mAir Canada

Wed 10/812:10 pmBCN - STL

1 stop14h 47mAir Canada

Deal found 9/15

$517

Mon 9/291:30 pmSTL - BCN

1 stop11h 20mUnited Airlines

Tue 10/1412:10 pmBCN - STL

2 stops29h 38mUnited Airlines

Deal found 9/15

$525

Tue 9/2311:33 amMCI - BCN

2 stops13h 17mUnited Airlines

Tue 9/3012:10 pmBCN - MCI

2 stops36h 16mUnited Airlines

Deal found 9/15

$525

Sun 11/21:37 pmMCI - MAD

1 stop12h 38mVirgin Atlantic

Tue 11/1811:15 amMAD - MCI

1 stop16h 55mVirgin Atlantic

Deal found 9/14

$528

Sun 9/285:00 amSTL - BCN

2 stops19h 50mUnited Airlines

Wed 10/1512:10 pmBCN - STL

2 stops29h 39mUnited Airlines

Deal found 9/15

$530

Best flights from Missouri to Spain
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2025.

Sun 10/121:30 pmSTL - MAD

1 stop10h 10mUnited Airlines

Wed 10/2212:45 pmMAD - STL

2 stops32h 42mUnited Airlines

Deal found 9/16

$418

Sun 10/121:30 pmSTL - MAD

1 stop10h 10mAir Canada

Wed 10/2212:30 pmMAD - STL

1 stop33h 48mAir Canada

Deal found 9/16

$437

Sat 10/115:25 pmSTL - MAD

1 stop33h 10mDelta

Tue 10/216:00 amMAD - STL

2 stops18h 29mDelta

Deal found 9/15

$476

Sun 11/234:05 pmSTL - MAD

2 stops56h 55mMultiple Airlines

Tue 12/22:00 pmMAD - STL

1 stop30h 55mMultiple Airlines

Deal found 9/16

$482

Wed 12/32:48 pmSTL - MAD

2 stops14h 52mIberia

Mon 12/811:35 amMAD - STL

1 stop14h 31mIberia

Deal found 9/16

$486

Tue 11/119:59 amMCI - BCN

2 stops25h 21mScandinavian Airlines

Sat 11/157:10 pmBCN - MCI

2 stops34h 25mScandinavian Airlines

Deal found 9/14

$499

Wed 9/2410:28 amMCI - MAD

1 stop16h 07mKLM

Tue 10/1412:40 pmMAD - MCI

1 stop35h 13mKLM

Deal found 9/13

$548

Sun 10/53:30 pmSTL - BIO

1 stop19h 55mLufthansa

Wed 10/156:45 amBIO - STL

2 stops15h 59mLufthansa

Deal found 9/15

$551

Wed 10/226:27 amSGF - MAD

1 stop16h 03mAmerican Airlines

Wed 11/1211:35 amMAD - SGF

1 stop16h 12mAmerican Airlines

Deal found 9/14

$557

Wed 10/812:36 pmMCI - BCN

1 stop13h 44mVirgin Atlantic

Wed 10/159:30 amBCN - MCI

2 stops18h 33mVirgin Atlantic

Deal found 9/14

$557

Mon 10/69:15 amSTL - MAD

1 stop16h 05mUnited Airlines

Wed 10/2212:30 pmMAD - STL

1 stop33h 48mUnited Airlines

Deal found 9/15

$444

Tue 10/73:59 pmSTL - MAD

2 stops17h 46mDelta

Tue 10/211:05 pmMAD - STL

2 stops26h 00mDelta

Deal found 9/15

$490

Sat 12/136:00 amSTL - SVQ

2 stops29h 05mAer Lingus

Fri 12/196:45 pmSVQ - STL

2 stops33h 22mAer Lingus

Deal found 9/14

$1,065

Tue 10/71:30 pmSTL - MAD

1 stop10h 10mUnited Airlines

Fri 10/1711:15 amMAD - STL

2 stops30h 34mUnited Airlines

Deal found 9/13

$491

Mon 9/225:27 pmMCI - MAD

1 stop33h 08mKLM

Tue 10/710:05 amMAD - MCI

1 stop13h 39mKLM

Deal found 9/16

$549

Sun 9/215:26 pmMCI - MAD

1 stop33h 09mMultiple Airlines

Tue 10/710:05 amMAD - MCI

1 stop13h 39mMultiple Airlines

Deal found 9/14

$550

Wed 10/2910:36 amSTL - VLC

2 stops27h 24mIberia

Wed 11/55:45 pmVLC - STL

2 stops34h 10mIberia

Deal found 9/14

$564

Mon 10/61:30 pmSTL - MAD

1 stop10h 10mUnited Airlines

Fri 10/1711:15 amMAD - STL

2 stops30h 34mUnited Airlines

Deal found 9/13

$491

Fri 10/314:05 pmSTL - VLC

2 stops20h 55mAir Canada

Fri 11/712:45 pmVLC - STL

2 stops33h 44mAir Canada

Deal found 9/15

$599

Mon 10/612:36 pmMCI - MAD

1 stop13h 59mKLM

Wed 10/2212:40 pmMAD - MCI

1 stop35h 13mKLM

Deal found 9/16

$549

Sun 9/218:04 amMCI - MAD

1 stop18h 31mDelta

Tue 10/712:40 pmMAD - MCI

2 stops17h 20mDelta

Deal found 9/14

$550

Tue 10/214:05 pmSGF - MAD

1 stop14h 20mMultiple Airlines

Tue 11/186:45 amMAD - SGF

2 stops17h 45mMultiple Airlines

Deal found 9/13

$596

Wed 12/33:27 pmMCI - MAD

1 stop10h 48mDelta

Tue 12/910:00 amMAD - MCI

2 stops18h 12mDelta

Deal found 9/15

$550

Wed 10/812:36 pmMCI - BCN

1 stop13h 44mKLM

Wed 10/159:30 amBCN - MCI

1 stop15h 34mKLM

Deal found 9/14

$553

Mon 9/291:30 pmSTL - BCN

1 stop11h 20mUnited Airlines

Wed 10/1512:10 pmBCN - STL

2 stops29h 39mUnited Airlines

Deal found 9/15

$525

Wed 10/299:43 amSTL - SVQ

2 stops40h 47mIberia

Wed 11/59:45 pmSVQ - STL

2 stops30h 10mIberia

Deal found 9/14

$654

Fri 10/314:05 pmSTL - VLC

2 stops20h 55mMultiple Airlines

Fri 11/76:10 amVLC - STL

1 stop14h 45mMultiple Airlines

Deal found 9/15

$600

Sun 10/129:50 amMCI - MAD

1 stop15h 00mDelta

Wed 10/2210:05 amMAD - MCI

1 stop13h 39mDelta

Deal found 9/14

$550

Wed 10/812:25 pmSTL - SVQ

2 stops16h 10mLufthansa

Tue 10/141:10 pmSVQ - STL

2 stops33h 34mLufthansa

Deal found 9/15

$734

Tue 11/2512:18 pmMCI - BCN

1 stop13h 22mKLM

Tue 12/210:55 amBCN - MCI

1 stop18h 49mKLM

Deal found 9/16

$553

Last-minute flights from Missouri to Spain
Discover last-minute flight deals from Missouri to Spain. Data last updated September 16, 2025 and is based on user searches.

Mon 9/221:30 pmSTL - BCN

1 stop11h 20mAir Canada

Wed 10/812:10 pmBCN - STL

1 stop14h 47mAir Canada

Deal found 9/15

$517

Tue 9/2311:33 amMCI - BCN

2 stops13h 17mUnited Airlines

Tue 9/3012:10 pmBCN - MCI

2 stops36h 16mUnited Airlines

Deal found 9/15

$525

Sun 9/285:00 amSTL - BCN

2 stops19h 50mUnited Airlines

Wed 10/1512:10 pmBCN - STL

2 stops29h 39mUnited Airlines

Deal found 9/15

$530

Mon 9/291:30 pmSTL - BCN

1 stop11h 20mUnited Airlines

Tue 10/1412:10 pmBCN - STL

2 stops29h 38mUnited Airlines

Deal found 9/15

$525

Mon 10/61:30 pmSTL - MAD

1 stop10h 10mAir Canada

Wed 10/2212:45 pmMAD - STL

2 stops33h 33mAir Canada

Deal found 9/15

$417

Mon 10/612:25 pmSTL - MAD

2 stops35h 15mUnited Airlines

Wed 10/2212:45 pmMAD - STL

2 stops33h 59mUnited Airlines

Deal found 9/13

$428

Mon 10/61:30 pmSTL - MAD

1 stop10h 10mUnited Airlines

Thu 10/166:00 amMAD - STL

2 stops16h 44mUnited Airlines

Deal found 9/15

$466

Tue 10/79:15 amSTL - MAD

1 stop16h 05mUnited Airlines

Wed 10/2211:15 amMAD - STL

2 stops18h 20mUnited Airlines

Deal found 9/13

$452

Tue 10/711:10 amSTL - MAD

2 stops14h 10mAir Canada

Tue 10/146:20 amMAD - STL

2 stops15h 58mAir Canada

Deal found 9/13

$465

Tue 10/76:30 amSTL - MAD

2 stops17h 10mAir Canada

Wed 10/2212:45 pmMAD - STL

2 stops32h 42mAir Canada

Deal found 9/13

$468

Sun 10/121:30 pmSTL - MAD

1 stop10h 10mUnited Airlines

Wed 10/2212:45 pmMAD - STL

2 stops32h 42mUnited Airlines

Deal found 9/16

$418

Mon 10/134:05 pmSTL - BCN

2 stops32h 45mAir Canada

Fri 10/3112:35 pmBCN - STL

2 stops35h 04mAir Canada

Deal found 9/14

$532

One-way flights from Missouri to Spain
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated September 16, 2025.

Wed 12/105:11 pmSTL - BCN

2 stops57h 39mMultiple Airlines

Deal found 9/14

$306

Mon 11/109:07 pmSTL - BCN

3 stops53h 08mMultiple Airlines

Deal found 9/14

$343

Wed 10/152:55 pmMCI - MAD

3 stops45h 25mMultiple Airlines

Deal found 9/15

$350

Thu 11/209:54 pmSTL - BCN

3 stops41h 51mMultiple Airlines

Deal found 9/14

$354

Tue 12/95:11 pmSTL - BIO

3 stops42h 24mMultiple Airlines

Deal found 9/15

$367

Tue 10/211:30 pmSTL - BCN

2 stops21h 40mScandinavian Airlines

Deal found 9/14

$376

Fri 11/73:59 pmSTL - MAD

2 stops18h 46mScandinavian Airlines

Deal found 9/14

$376

Sat 11/157:45 pmSTL - SVQ

3 stops31h 25mMultiple Airlines

Deal found 9/15

$380

Wed 10/156:40 amSTL - MAD

2 stops18h 10mDelta

Deal found 9/14

$382

Wed 10/153:57 pmSTL - MAD

3 stops43h 38mMultiple Airlines

Deal found 9/14

$387

Mon 10/203:59 pmSTL - BCN

2 stops19h 11mScandinavian Airlines

Deal found 9/14

$391

Sun 11/234:05 pmSTL - MAD

2 stops56h 55mAir Canada

Deal found 9/15

$394

Fly from

Fly to

Route

Depart

Return

Price

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Sun 10/12

1:30 pm-6:40 am

1 stop10h 10m

Madrid Barajas

Wed 10/22

12:45 pm-2:27 pm

2 stops32h 42m

$418

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Sun 10/12

1:30 pm-6:40 am

1 stop10h 10m

Madrid Barajas

Wed 10/22

12:30 pm-3:18 pm

1 stop33h 48m

$437

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Mon 10/6

9:15 am-8:20 am

1 stop16h 05m

Madrid Barajas

Wed 10/22

12:30 pm-3:18 pm

1 stop33h 48m

$444

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Sat 10/11

5:25 pm-9:35 am

1 stop33h 10m

Madrid Barajas

Tue 10/21

6:00 am-5:29 pm

2 stops18h 29m

$476

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Sun 11/23

4:05 pm-8:00 am

2 stops56h 55m

Madrid Barajas

Tue 12/2

2:00 pm-1:55 pm

1 stop30h 55m

$482

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 12/3

2:48 pm-12:40 pm

2 stops14h 52m

Madrid Barajas

Mon 12/8

11:35 am-7:06 pm

1 stop14h 31m

$486

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 10/7

3:59 pm-4:45 pm

2 stops17h 46m

Madrid Barajas

Tue 10/21

1:05 pm-8:05 am

2 stops26h 00m

$490

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 10/7

1:30 pm-6:40 am

1 stop10h 10m

Madrid Barajas

Fri 10/17

11:15 am-10:49 am

2 stops30h 34m

$491

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Mon 10/6

1:30 pm-6:40 am

1 stop10h 10m

Madrid Barajas

Fri 10/17

11:15 am-10:49 am

2 stops30h 34m

$491

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Tue 11/11

9:59 am-6:20 pm

2 stops25h 21m

Barcelona-El Prat

Sat 11/15

7:10 pm-10:35 pm

2 stops34h 25m

$499

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Spain as you normally would.

Related info for your journey

How long is the flight from Missouri to Spain?
United Airlines, Air Canada, and Scandinavian Airlines can get you from Missouri to Spain in just under 10h 10m. Your travel time can differ by up to 15h 11m. There are 4414 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Missouri to Spain one-way?
The cheapest airline one-way is Scandinavian Airlines, with whom users have recently found tickets for as low as $376. However, be on the lookout for offers from KLM and Delta, as they are both options that can get you from Missouri to Spain for a low price.
Can I find deals for flights from Missouri to Spain that include hotel bookings?
Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Spain?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.
Can I find deals for business class flights from Missouri to Spain?
Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Spain?
Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 10 airlines flying from Missouri to Spain

Airline	Cheapest	Average	Flexibility	On-time
KLM	Cheapest$483	Average$753	FlexibilityNo cancel fee	On-time75%
Delta	Cheapest$492	Average$888	FlexibilityNo cancel fee	On-timeN/A
Air France	Cheapest$533	Average$793	FlexibilityNo cancel fee	On-time77%
United Airlines	Cheapest$533	Average$968	FlexibilityNo cancel fee	On-time69%
British Airways	Cheapest$546	Average$929	FlexibilityNo cancel fee	On-time70%
Iberia	Cheapest$578	Average$1,073	FlexibilityNo cancel fee	On-time77%
Virgin Atlantic	Cheapest$580	Average$655	FlexibilityNo cancel fee	On-time72%
American Airlines	Cheapest$584	Average$1,113	FlexibilityNo cancel fee	On-time71%
Lufthansa	Cheapest$605	Average$1,093	FlexibilityNo cancel fee	On-time76%
Air Canada	Cheapest$624	Average$1,108	FlexibilityNo cancel fee	On-time67%

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$306+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated September 16, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Spain

Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missouri to Spain?

What are the cheapest airlines to fly from Missouri to Spain one-way?

Can I find deals for flights from Missouri to Spain that include hotel bookings?

How can I find direct flights from Missouri to Spain?

Can I find deals for business class flights from Missouri to Spain?

What is the cheapest month to book a flight from Missouri to Spain?

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Missouri to Spain

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Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.