$355+ Cheap flights from Missouri to Spain
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Oct 30 — Nov 61
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This Expedia deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:50 pm -
2 stops30h 10m
Wed 12/96:05 am -
1 stop14h 40m
Deal found 9/27![Multiple Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am -
2 stops20h 00m
Fri 1/151:35 pm -
2 stops32h 15m
Deal found 9/26![United Airlines logo]()
$706
This Expedia deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:41 am -
1 stop15h 29m
Fri 12/111:00 pm -
1 stop16h 02m
Deal found 9/25![Iberia logo]()
$708
This Flighttix deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:00 pm -
1 stop12h 45m
Wed 11/116:05 am -
1 stop14h 40m
Deal found 9/25![Lufthansa logo]()
$708
This Air Canada deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
2 stops20h 35m
Wed 11/111:35 pm -
2 stops39h 05m
Deal found 9/27![Air Canada logo]()
$709
This Flighttix deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:50 pm -
1 stop12h 25m
Wed 11/116:50 am -
1 stop13h 55m
Deal found 9/28![Lufthansa logo]()
$710
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:10 am -
1 stop20h 20m
Wed 11/181:25 pm -
2 stops37h 30m
Deal found 9/28![United Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:00 pm -
1 stop11h 45m
Tue 11/171:25 pm -
2 stops33h 18m
Deal found 9/29![United Airlines logo]()
$710
This Expedia deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:45 am -
2 stops19h 15m
Wed 1/137:30 pm -
2 stops33h 15m
Deal found 9/27![Multiple Airlines logo]()
$711
This Flighttix deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:45 pm -
1 stop12h 30m
Tue 11/105:55 am -
2 stops22h 56m
Deal found 9/26![Lufthansa logo]()
$711
This Gotogate deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:40 pm -
1 stop13h 55m
Wed 11/186:05 am -
1 stop14h 40m
Deal found 9/27![Lufthansa logo]()
$712
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:45 am -
2 stops16h 15m
Thu 11/261:25 pm -
2 stops37h 18m
Deal found 9/28![United Airlines logo]()
$713
Best flights from Missouri to SpainDiscover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am -
2 stops20h 00m
Fri 1/151:35 pm -
2 stops32h 15m
Deal found 9/26![United Airlines logo]()
$706
This Expedia deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:29 am -
1 stop16h 26m
Tue 11/2412:00 pm -
1 stop15h 33m
Deal found 9/26![Iberia logo]()
$726
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:10 am -
1 stop17h 30m
Tue 12/810:35 am -
1 stop15h 17m
Deal found 9/25![Delta logo]()
$726
This Justfly.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:45 pm -
2 stops15h 45m
Tue 11/247:35 pm -
2 stops33h 16m
Deal found 9/28![Multiple Airlines logo]()
$774
This Virgin Atlantic deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2912:29 pm -
1 stop14h 16m
Sun 12/612:20 pm -
1 stop16h 18m
Deal found 9/25![Virgin Atlantic logo]()
$777
This Lufthansa deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:08 pm -
2 stops20h 07m
Tue 11/175:10 pm -
1 stop27h 35m
Deal found 9/26![Lufthansa logo]()
$879
This KLM deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:00 pm -
2 stops14h 30m
Fri 10/301:05 pm -
2 stops16h 49m
Deal found 9/29![KLM logo]()
$959
This Air Canada deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:09 pm -
3 stops22h 36m
Tue 11/2412:50 pm -
3 stops30h 33m
Deal found 9/29![Air Canada logo]()
$979
This Turkish Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:00 am -
2 stops31h 35m
Mon 11/26:00 pm -
2 stops34h 40m
Deal found 9/25![Turkish Airlines logo]()
$1,040
This British Airways deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/11:05 pm -
2 stops16h 40m
Fri 2/59:15 am -
2 stops20h 19m
Deal found 9/25![British Airways logo]()
$1,061
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:16 pm -
1 stop13h 59m
Tue 11/1010:30 am -
2 stops18h 21m
Deal found 9/25![United Airlines logo]()
$716
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:44 pm -
2 stops15h 46m
Tue 11/106:00 am -
2 stops18h 10m
Deal found 9/25![Delta logo]()
$738
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:33 am -
1 stop14h 27m
Tue 11/1010:30 am -
1 stop16h 25m
Deal found 9/28![United Airlines logo]()
$726
This Air France deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:21 pm -
2 stops14h 39m
Tue 11/178:25 pm -
2 stops27h 06m
Deal found 9/26![Multiple Airlines logo]()
$799
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:47 am -
2 stops17h 33m
Thu 10/291:10 pm -
2 stops16h 44m
Deal found 9/25![Delta logo]()
$789
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:02 am -
1 stop19h 18m
Tue 12/811:00 am -
1 stop19h 35m
Deal found 9/29![United Airlines logo]()
$726
This Lufthansa deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:08 pm -
2 stops15h 52m
Thu 11/196:20 pm -
1 stop26h 25m
Deal found 9/28![Lufthansa logo]()
$883
This Finnair deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/151:43 pm -
1 stop12h 07m
Fri 12/2512:00 pm -
2 stops28h 27m
Deal found 9/27![Multiple Airlines logo]()
$815
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:41 pm -
1 stop12h 34m
Tue 11/1710:30 am -
1 stop16h 25m
Deal found 9/27![United Airlines logo]()
$726
This Lufthansa deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:08 pm -
2 stops20h 02m
Thu 11/195:10 pm -
1 stop27h 35m
Deal found 9/28![Lufthansa logo]()
$884
This KLM deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:06 am -
2 stops17h 09m
Fri 12/2510:45 am -
2 stops29h 22m
Deal found 9/25![KLM logo]()
$977
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:58 pm -
1 stop10h 47m
Mon 12/1412:20 pm -
1 stop14h 59m
Deal found 9/25![Delta logo]()
$830
This Finnair deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:47 pm -
1 stop14h 03m
Tue 11/36:45 pm -
2 stops25h 33m
Deal found 9/28![Multiple Airlines logo]()
$845
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:50 pm -
2 stops31h 45m
Tue 11/173:10 pm -
1 stop13h 30m
Deal found 9/29![United Airlines logo]()
$729
This FlightHub deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:00 pm -
2 stops17h 30m
Thu 11/51:20 pm -
1 stop31h 25m
Deal found 9/25![Lufthansa logo]()
$904
This Air France deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:00 pm -
2 stops21h 45m
Thu 11/510:50 am -
2 stops40h 06m
Deal found 9/25![Multiple Airlines logo]()
$878
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:33 am -
1 stop13h 12m
Tue 11/176:05 am -
2 stops20h 50m
Deal found 9/26![United Airlines logo]()
$730
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:28 pm -
2 stops14h 02m
Fri 10/3010:50 am -
2 stops19h 04m
Deal found 9/28![Delta logo]()
$959
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:33 am -
1 stop13h 12m
Thu 11/2611:00 am -
1 stop15h 55m
Deal found 9/29![United Airlines logo]()
$730
This Iberia deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/153:41 pm -
2 stops18h 09m
Wed 11/189:10 am -
2 stops20h 40m
Deal found 9/25![Iberia logo]()
$1,310
Last-minute flights from Missouri to SpainDiscover last-minute flight deals from Missouri to Spain. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Spain. Data last updated September 30, 2026 and is based on user searches.
This Flighttix deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:00 pm -
1 stop12h 45m
Wed 11/116:05 am -
1 stop14h 40m
Deal found 9/25![Lufthansa logo]()
$708
This Flighttix deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:50 pm -
1 stop12h 25m
Wed 11/116:50 am -
1 stop13h 55m
Deal found 9/28![Lufthansa logo]()
$710
This Gotogate deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:05 pm -
2 stops32h 55m
Wed 11/111:25 pm -
2 stops33h 01m
Deal found 9/25![Air Canada logo]()
$714
This United deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
2 stops21h 00m
Wed 11/116:50 am -
1 stop13h 55m
Deal found 9/28![Multiple Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:00 pm -
1 stop12h 45m
Wed 11/116:05 am -
1 stop14h 40m
Deal found 9/25![United Airlines logo]()
$716
This Flighttix deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:33 am -
1 stop14h 12m
Wed 11/1111:15 am -
1 stop16h 24m
Deal found 9/27![Lufthansa logo]()
$717
This Expedia deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:14 pm -
2 stops15h 21m
Wed 11/1112:00 pm -
1 stop13h 48m
Deal found 9/27![Iberia logo]()
$720
This United deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:50 pm -
2 stops30h 55m
Wed 11/116:05 am -
1 stop14h 40m
Deal found 9/25![Multiple Airlines logo]()
$721
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:32 pm -
1 stop11h 58m
Wed 11/116:05 am -
2 stops20h 50m
Deal found 9/27![United Airlines logo]()
$722
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:33 am -
1 stop14h 12m
Tue 11/108:35 am -
2 stops19h 04m
Deal found 9/29![United Airlines logo]()
$730
This Priceline deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:14 pm -
2 stops16h 01m
Wed 11/111:30 pm -
1 stop17h 07m
Deal found 9/29![Iberia logo]()
$727
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:18 am -
2 stops14h 27m
Wed 11/116:25 am -
2 stops17h 09m
Deal found 9/29![United Airlines logo]()
$731
One-way flights from Missouri to SpainSearch for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:32 pm -
3 stops42h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$355
This Cheapflightsfares deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/93:22 pm -
2 stops24h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![SWISS logo]()
$367
This Justfly.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/92:49 pm -
2 stops20h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![British Airways logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:43 pm -
3 stops53h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/97:00 am -
1 stop17h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![American Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:43 pm -
3 stops43h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$378
This Expedia deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/318:26 am -
1 stop17h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Iberia logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/218:31 pm -
3 stops43h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$390
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/319:35 am -
2 stops16h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![United Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:43 pm -
3 stops42h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:43 pm -
3 stops39h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:43 pm -
3 stops44h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$409
Find flight deals from Missouri to Spain
Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated September 30, 2026.
Round-trip from | $701 (Expedia) |
|---|---|
One-way from | $355 (Kiwi.com) |
Popular in | June |
Cheapest in | April |
Average price | $980 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Sat 12/12
8:32 pm-9:55 pm
3 stops42h 23m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$355
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Tue 3/9
2:49 pm-6:25 pm
2 stops20h 36m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$371
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Tue 3/9
7:00 am-7:05 am
1 stop17h 05m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$375
Kansas CityValencia
MCI Kansas City - VLC Valencia
MCIVLC
Kansas City
Tue 11/10
8:43 pm-11:10 pm
3 stops43h 27m
Valencia
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$378
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Thu 12/31
8:26 am-9:25 am
1 stop17h 59m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$380
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Thu 1/21
8:31 pm-10:55 pm
3 stops43h 24m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$390
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Thu 12/31
9:35 am-9:30 am
2 stops16h 55m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$391
Kansas CityMálaga
MCI Kansas City - AGP Malaga
MCIAGP
Kansas City
Tue 11/10
8:43 pm-7:25 pm
3 stops39h 42m
Malaga
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$401
Kansas CityMálaga
MCI Kansas City - AGP Malaga
MCIAGP
Kansas City
Thu 11/12
8:43 pm-11:55 pm
3 stops44h 12m
Malaga
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$409
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Mon 11/2
6:44 pm-8:00 am
3 stops30h 16m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$409
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
STL-MAD
STL-BCN
MCI-MAD
MCI-BCN
MCI-VLC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Spain
USMO-ES0
STL-MAD
STL-BCN
MCI-MAD
MCI-BCN
What is the cheapest month to book a flight from Missouri to Spain?
Currently, February is the cheapest month in which you can book a flight from Missouri to Spain (average of $630). Flying from Missouri to Spain in June is currently the most expensive (average of $1,474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Missouri to Spain?
Booking 70 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Top regions
Alternative routes for Missouri to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Spain by cabin class
Find flights from Missouri to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Spain flights
Browse other Missouri and Spain flight options. Last updated on September 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Spain
Find the right flight back to Missouri after your stay in Spain
Missouri to Spain flights
Consider these flights traveling from Missouri to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 8 airlines flying from Missouri to Spain
Discover the top 8 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$382 | Average$656 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$452 | Average$857 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$461 | Average$941 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$480 | Average$1,207 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$485 | Average$938 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$488 | Average$938 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$490 | Average$1,012 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$648 | Average$1,173 | FlexibilityNo cancel fee | On-time67% |