How long is the flight from Missouri to Spain?

Lufthansa, United Airlines, and Air Canada can get you from Missouri to Spain in just under 14h 36m. Your travel time can differ by up to 22h 09m. There are 4414 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Missouri to Spain one-way?

The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $322. However, be on the lookout for offers from United Airlines and Lufthansa, as they are both options that can get you from Missouri to Spain for a low price.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

What is the cheapest time of day to fly from MO to ES?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Spain as you normally would.

Can I find deals for flights from Missouri to Spain that include hotel bookings?

Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Spain?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

Can I find deals for business class flights from Missouri to Spain?

Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$271+ Flights from Missouri to Spain

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Missouri to Spain with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.

Wed 12/3112:29 pmSTL - MAD

2 stops22h 21mLufthansa

Tue 1/66:35 pmMAD - STL

2 stops35h 23mLufthansa

Deal found 12/30

$16,131

Wed 12/313:30 pmSTL - MAD

1 stop34h 55mBritish Airways

Tue 1/612:50 pmMAD - STL

2 stops33h 00mBritish Airways

Deal found 12/30

$17,603

Best flights from Missouri to Spain
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 2, 2026.

Tue 2/1711:39 amSTL - MAD

1 stop14h 36mLufthansa

Sun 3/15:55 amMAD - STL

1 stop15h 00mLufthansa

Deal found 12/30

$461

Sat 2/281:50 pmMCI - BCN

2 stops36h 45mUnited Airlines

Tue 3/1012:35 pmBCN - MCI

2 stops31h 45mUnited Airlines

Deal found 12/31

$468

Fri 3/67:41 amSTL - BCN

2 stops18h 54mAir Canada

Thu 3/1212:35 pmBCN - STL

2 stops32h 08mAir Canada

Deal found 1/1

$469

Tue 3/311:59 amSTL - BCN

2 stops16h 21mBritish Airways

Tue 3/109:35 amBCN - STL

1 stop19h 47mBritish Airways

Deal found 12/30

$473

Mon 3/95:54 amMCI - BCN

1 stop19h 41mDelta

Wed 3/189:15 amBCN - MCI

1 stop16h 04mDelta

Deal found 1/1

$484

Sat 2/1412:37 pmMCI - VLC

2 stops16h 23mMultiple Airlines

Sat 2/216:00 amVLC - MCI

2 stops22h 59mMultiple Airlines

Deal found 12/31

$488

Tue 3/1010:20 amSTL - MAD

1 stop13h 25mAmerican Airlines

Thu 3/1912:00 pmMAD - STL

1 stop15h 11mAmerican Airlines

Deal found 12/30

$489

Wed 2/410:44 amMCI - SVQ

2 stops16h 16mKLM

Wed 2/258:15 pmSVQ - MCI

2 stops30h 52mKLM

Deal found 12/30

$572

Sat 2/75:48 amMCI - SVQ

2 stops19h 42mIberia

Mon 2/169:45 pmSVQ - MCI

2 stops18h 12mIberia

Deal found 12/31

$586

Sat 2/285:21 pmMCI - BCN

2 stops33h 14mUnited Airlines

Mon 3/912:35 pmBCN - MCI

2 stops38h 06mUnited Airlines

Deal found 12/31

$468

Wed 2/2512:37 pmMCI - VLC

2 stops15h 23mLufthansa

Sun 3/16:00 amVLC - MCI

2 stops21h 06mLufthansa

Deal found 1/1

$470

Sun 3/14:05 pmSTL - BCN

2 stops34h 30mAir Canada

Mon 3/912:35 pmBCN - STL

2 stops32h 14mAir Canada

Deal found 1/2

$472

Mon 3/26:36 pmSTL - MAD

2 stops15h 19mBritish Airways

Wed 3/1111:25 amMAD - STL

1 stop17h 33mBritish Airways

Deal found 12/31

$475

Wed 3/411:59 amSTL - MAD

1 stop15h 21mMultiple Airlines

Wed 3/114:25 pmMAD - STL

1 stop24h 07mMultiple Airlines

Deal found 12/30

$489

Wed 3/116:35 amMCI - BCN

2 stops18h 25mDelta

Wed 3/189:45 amBCN - MCI

1 stop18h 18mDelta

Deal found 1/1

$490

Sat 2/217:55 amSGF - BCN

2 stops18h 05mUnited Airlines

Mon 3/21:35 pmBCN - SGF

2 stops39h 24mUnited Airlines

Deal found 12/31

$469

Mon 2/238:00 amMCI - MAD

2 stops17h 00mAir Canada

Mon 3/21:35 pmMAD - MCI

2 stops31h 49mAir Canada

Deal found 1/1

$473

Thu 3/58:00 amSTL - MAD

2 stops22h 35mBritish Airways

Thu 3/121:00 pmMAD - STL

1 stop16h 48mBritish Airways

Deal found 12/31

$475

Fri 2/2011:32 amMCI - MAD

2 stops29h 03mLufthansa

Sun 3/15:55 amMAD - MCI

2 stops23h 04mLufthansa

Deal found 12/31

$477

Mon 2/236:16 pmMCI - MAD

2 stops17h 54mDelta

Sun 3/111:15 amMAD - MCI

1 stop19h 25mDelta

Deal found 1/1

$493

Tue 4/146:30 amSTL - BCN

2 stops18h 50mUnited Airlines

Tue 4/2812:15 pmBCN - STL

2 stops39h 53mUnited Airlines

Deal found 1/1

$470

Thu 1/2911:29 amMCI - MAD

2 stops29h 06mLufthansa

Sat 2/77:25 amMAD - MCI

2 stops17h 02mLufthansa

Deal found 1/1

$481

Wed 2/186:36 pmSTL - MAD

2 stops16h 54mBritish Airways

Wed 2/2512:50 pmMAD - STL

2 stops17h 58mBritish Airways

Deal found 12/31

$481

Wed 4/156:42 pmMCI - AGP

2 stops17h 33mKLM

Thu 4/3011:55 pmAGP - MCI

2 stops22h 21mKLM

Deal found 1/1

$592

Sat 2/2110:54 amMCI - SVQ

2 stops14h 36mIberia

Sun 3/19:45 pmSVQ - MCI

2 stops31h 57mIberia

Deal found 12/31

$596

Thu 3/56:35 amSTL - MAD

2 stops25h 45mDelta

Thu 3/1210:05 amMAD - STL

1 stop19h 53mDelta

Deal found 12/30

$493

Thu 1/298:05 amMCI - MAD

2 stops16h 55mUnited Airlines

Thu 2/51:35 pmMAD - MCI

2 stops39h 24mUnited Airlines

Deal found 12/31

$472

Tue 2/176:31 pmSTL - MAD

2 stops18h 29mBritish Airways

Sun 3/17:20 pmMAD - STL

2 stops34h 44mBritish Airways

Deal found 12/31

$481

Tue 3/174:48 pmMCI - BCN

2 stops16h 12mDelta

Tue 3/249:15 amBCN - MCI

2 stops18h 48mDelta

Deal found 1/1

$493

Tue 4/145:45 pmMCI - AGP

2 stops17h 10mLufthansa

Thu 4/306:45 pmAGP - MCI

2 stops52h 39mLufthansa

Deal found 1/1

$506

Last-minute flights from Missouri to Spain
Discover last-minute flight deals from Missouri to Spain. Data last updated January 2, 2026 and is based on user searches.

Wed 1/2811:22 amSTL - MAD

1 stop14h 53mLufthansa

Wed 2/48:30 amMAD - STL

2 stops17h 57mLufthansa

Deal found 12/29

$470

Wed 1/2810:17 amSTL - MAD

1 stop12h 28mBritish Airways

Wed 2/412:40 pmMAD - STL

1 stop17h 19mBritish Airways

Deal found 12/29

$487

Wed 1/289:57 amSTL - MAD

2 stops16h 18mUnited Airlines

Wed 2/48:30 amMAD - STL

3 stops19h 43mUnited Airlines

Deal found 12/29

$494

Thu 1/296:23 pmMCI - MAD

2 stops30h 37mVirgin Atlantic

Wed 2/1110:00 amMAD - MCI

2 stops19h 02mVirgin Atlantic

Deal found 1/1

$465

Thu 1/298:05 amMCI - MAD

2 stops16h 55mUnited Airlines

Thu 2/51:35 pmMAD - MCI

2 stops39h 24mUnited Airlines

Deal found 12/31

$472

Thu 1/291:56 pmMCI - MAD

1 stop12h 29mFinnair

Wed 2/1112:40 pmMAD - MCI

1 stop15h 47mFinnair

Deal found 1/1

$473

Thu 1/296:00 amMCI - MAD

2 stops22h 55mBritish Airways

Thu 2/51:00 pmMAD - MCI

1 stop15h 27mBritish Airways

Deal found 12/31

$475

Thu 1/296:00 amMCI - MAD

2 stops22h 55mBritish Airways

Sat 2/712:40 pmMAD - MCI

1 stop17h 52mBritish Airways

Deal found 1/1

$476

Thu 1/296:23 pmMCI - MAD

1 stop31h 52mKLM

Wed 2/1110:00 amMAD - MCI

2 stops19h 02mKLM

Deal found 1/1

$480

Thu 1/2911:29 amMCI - MAD

2 stops29h 06mLufthansa

Sat 2/77:25 amMAD - MCI

2 stops17h 02mLufthansa

Deal found 1/1

$481

Sat 1/3112:44 pmSTL - BCN

2 stops18h 31mUnited Airlines

Sat 2/76:45 amBCN - STL

2 stops19h 42mUnited Airlines

Deal found 1/1

$500

Sat 1/3112:06 pmSTL - BCN

2 stops25h 09mBritish Airways

Sat 2/712:30 pmBCN - STL

1 stop17h 14mBritish Airways

Deal found 1/1

$513

One-way flights from Missouri to Spain
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated January 2, 2026.

Mon 3/1612:16 pmSTL - MAD

3 stops41h 54mMultiple Airlines

Deal found 12/30

$271

Fri 4/248:01 pmMCI - BCN

2 stops17h 14mBritish Airways

Deal found 1/1

$305

Mon 3/166:00 amSTL - MAD

2 stops21h 55mAer Lingus

Deal found 12/30

$329

Sun 5/107:25 pmMCI - MAD

1 stop27h 55mDelta

Deal found 1/1

$332

Sun 5/104:51 pmMCI - MAD

2 stops33h 44mBritish Airways

Deal found 1/1

$346

Sun 5/176:45 amSTL - BCN

2 stops19h 00mDelta

Deal found 1/1

$350

Tue 5/195:30 pmSTL - BCN

2 stops14h 20mAir France

Deal found 12/31

$354

Wed 3/116:00 amMCI - BCN

2 stops22h 50mAer Lingus

Deal found 1/1

$372

Thu 3/54:05 pmSTL - BCN

2 stops34h 30mAir Canada

Deal found 12/31

$404

Fri 4/2412:12 pmMCI - BCN

3 stops42h 08mMultiple Airlines

Deal found 1/1

$413

Sun 5/179:40 pmSTL - BCN

1 stop14h 50mMultiple Airlines

Deal found 1/1

$440

Wed 5/2710:45 amSTL - BCN

2 stops16h 20mWestJet

Deal found 1/2

$442

Find flight deals from Missouri to Spain

Round-trip from	$461 (Cheapflightsfares)
One-way from	$271 (Kiwi.com)
Popular in	June
Cheapest in	February
Average price	$744

From Missouri to Spain

Search Deals

One-way flight from Missouri to Spain

Search Deals

Highest demand for flights based on searches. 23% potential increase in price ($278 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in January 2026

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 2/17

11:39 am-9:15 am

1 stop14h 36m

Madrid Barajas

Sun 3/1

5:55 am-1:55 pm

1 stop15h 00m

$461

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Sat 2/28

1:50 pm-9:35 am

2 stops36h 45m

Barcelona-El Prat

Tue 3/10

12:35 pm-2:20 pm

2 stops31h 45m

$468

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Sat 2/28

5:21 pm-9:35 am

2 stops33h 14m

Barcelona-El Prat

Mon 3/9

12:35 pm-8:41 pm

2 stops38h 06m

$468

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Fri 3/6

7:41 am-9:35 am

2 stops18h 54m

Barcelona-El Prat

Thu 3/12

12:35 pm-2:43 pm

2 stops32h 08m

$469

SpringfieldBarcelona

SGF - BCN

SGFBCN

Springfield-Branson

Sat 2/21

7:55 am-9:00 am

2 stops18h 05m

Barcelona-El Prat

Mon 3/2

1:35 pm-9:59 pm

2 stops39h 24m

$469

Kansas CityValencia

MCI - VLC

MCIVLC

Kansas City

Wed 2/25

12:37 pm-11:00 am

2 stops15h 23m

Valencia

Sun 3/1

6:00 am-8:06 pm

2 stops21h 06m

$470

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 4/14

6:30 am-8:20 am

2 stops18h 50m

Barcelona-El Prat

Tue 4/28

12:15 pm-9:08 pm

2 stops39h 53m

$470

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Sun 3/1

4:05 pm-9:35 am

2 stops34h 30m

Barcelona-El Prat

Mon 3/9

12:35 pm-2:49 pm

2 stops32h 14m

$472

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Thu 1/29

8:05 am-8:00 am

2 stops16h 55m

Madrid Barajas

Thu 2/5

1:35 pm-9:59 pm

2 stops39h 24m

$472

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 3/3

11:59 am-11:20 am

2 stops16h 21m

Barcelona-El Prat

Tue 3/10

9:35 am-11:22 pm

1 stop19h 47m

$473

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $449). Flying from Missouri to Spain in May is currently the most expensive (average of $823). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

How long is the flight from Missouri to Spain?
Lufthansa, United Airlines, and Air Canada can get you from Missouri to Spain in just under 14h 36m. Your travel time can differ by up to 22h 09m. There are 4414 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Missouri to Spain one-way?
The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $322. However, be on the lookout for offers from United Airlines and Lufthansa, as they are both options that can get you from Missouri to Spain for a low price.
Can I find deals for flights from Missouri to Spain that include hotel bookings?
Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Spain?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.
Can I find deals for business class flights from Missouri to Spain?
Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Spain?
Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $449). Flying from Missouri to Spain in May is currently the most expensive (average of $823). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 10 airlines flying from Missouri to Spain

Airline	Cheapest	Average	Flexibility	On-time
KLM	Cheapest$433	Average$763	FlexibilityNo cancel fee	On-time75%
Virgin Atlantic	Cheapest$437	Average$756	FlexibilityNo cancel fee	On-time72%
British Airways	Cheapest$483	Average$891	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$487	Average$873	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$488	Average$1,098	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$498	Average$956	FlexibilityNo cancel fee	On-time69%
Lufthansa	Cheapest$524	Average$1,066	FlexibilityNo cancel fee	On-time76%
Air France	Cheapest$533	Average$752	FlexibilityNo cancel fee	On-time77%
Iberia	Cheapest$578	Average$1,013	FlexibilityNo cancel fee	On-time77%
Air Canada	Cheapest$624	Average$1,082	FlexibilityNo cancel fee	On-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$271+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Spain with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missouri to Spain

Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.

Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.

Find flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated January 2, 2026.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missouri to Spain?

What are the cheapest airlines to fly from Missouri to Spain one-way?

Can I find deals for flights from Missouri to Spain that include hotel bookings?

How can I find direct flights from Missouri to Spain?

Can I find deals for business class flights from Missouri to Spain?

What is the cheapest month to book a flight from Missouri to Spain?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Missouri to Spain

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.