$336+ Cheap flights from Missouri to Spain
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Spain
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Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Rumbo deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:30 pm -
2 stops32h 05m
Wed 12/1610:35 am -
2 stops20h 30m
Deal found 10/27![Virgin Atlantic logo]()
$735
This Gotogate deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:05 pm -
2 stops15h 00m
Fri 1/156:50 am -
1 stop13h 55m
Deal found 10/29![Multiple Airlines logo]()
$742
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:00 am -
1 stop14h 20m
Fri 12/251:35 pm -
2 stops35h 43m
Deal found 10/29![United Airlines logo]()
$744
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:10 am -
1 stop19h 10m
Fri 1/151:35 pm -
2 stops40h 45m
Deal found 10/28![United Airlines logo]()
$745
This Sembo deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sembo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:53 am -
2 stops14h 07m
Wed 12/96:05 am -
1 stop14h 40m
Deal found 10/25![Multiple Airlines logo]()
$746
This United deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:00 am -
1 stop15h 30m
Fri 12/251:30 pm -
2 stops35h 48m
Deal found 10/29![Multiple Airlines logo]()
$749
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/133:52 pm -
2 stops15h 18m
Fri 1/1512:00 pm -
1 stop32h 08m
Deal found 10/28![American Airlines logo]()
$750
This United deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:50 am -
2 stops15h 10m
Wed 12/236:50 am -
1 stop13h 55m
Deal found 10/29![Multiple Airlines logo]()
$751
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop20h 30m
Wed 12/166:05 am -
1 stop14h 40m
Deal found 10/28![United Airlines logo]()
$751
This Booking.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:03 am -
1 stop20h 07m
Fri 1/1512:00 pm -
1 stop16h 09m
Deal found 10/28![British Airways logo]()
$751
This Justfly.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:02 am -
2 stops40h 58m
Fri 12/251:30 pm -
2 stops33h 38m
Deal found 10/29![Air Canada logo]()
$752
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:11 am -
2 stops23h 39m
Wed 12/96:05 am -
2 stops18h 48m
Deal found 10/27![Lufthansa logo]()
$753
Best flights from Missouri to SpainDiscover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/26:15 am -
2 stops22h 45m
Thu 3/46:05 am -
2 stops16h 21m
Deal found 10/27![United Airlines logo]()
$737
This United deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:10 am -
1 stop19h 10m
Fri 1/156:50 am -
1 stop13h 55m
Deal found 10/26![Multiple Airlines logo]()
$748
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:11 am -
2 stops23h 39m
Wed 12/96:05 am -
2 stops18h 48m
Deal found 10/27![Lufthansa logo]()
$753
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/291:09 pm -
2 stops20h 21m
Fri 2/511:55 am -
2 stops18h 54m
Deal found 10/27![Iberia logo]()
$770
This FlightHub deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/126:06 pm -
2 stops14h 44m
Wed 4/2811:45 am -
1 stop19h 14m
Deal found 10/30![British Airways logo]()
$772
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1010:14 am -
2 stops15h 46m
Fri 1/2910:50 am -
1 stop16h 25m
Deal found 10/26![Delta logo]()
$773
This KLM deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:20 pm -
1 stop12h 20m
Thu 12/1710:35 am -
1 stop15h 17m
Deal found 10/26![KLM logo]()
$805
This Virgin Atlantic deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:29 pm -
1 stop14h 16m
Fri 12/412:20 pm -
1 stop16h 18m
Deal found 10/29![Virgin Atlantic logo]()
$819
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/166:16 pm -
2 stops17h 14m
Wed 3/3110:30 am -
1 stop14h 16m
Deal found 10/26![American Airlines logo]()
$823
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:00 am -
1 stop14h 20m
Fri 12/251:35 pm -
2 stops35h 43m
Deal found 10/29![United Airlines logo]()
$744
This United deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am -
2 stops19h 20m
Fri 1/151:35 pm -
2 stops28h 40m
Deal found 10/28![Multiple Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/412:16 pm -
2 stops23h 24m
Wed 4/215:20 pm -
2 stops32h 49m
Deal found 10/30![Delta logo]()
$788
This KLM deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:20 pm -
1 stop12h 20m
Tue 11/1710:35 am -
1 stop15h 28m
Deal found 10/25![KLM logo]()
$805
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
2 stops19h 00m
Wed 1/131:25 pm -
2 stops39h 24m
Deal found 10/26![United Airlines logo]()
$752
This Cheapflightsfares deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/103:40 pm -
1 stop13h 20m
Sat 4/246:15 am -
1 stop14h 10m
Deal found 10/29![Lufthansa logo]()
$834
This Finnair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/205:05 am -
1 stop20h 45m
Wed 1/2712:00 pm -
1 stop18h 57m
Deal found 10/25![Multiple Airlines logo]()
$774
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:40 am -
2 stops17h 20m
Tue 12/81:00 pm -
2 stops27h 35m
Deal found 10/26![Delta logo]()
$804
This KLM deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/72:16 pm -
2 stops14h 59m
Wed 1/271:10 pm -
2 stops17h 48m
Deal found 10/26![KLM logo]()
$832
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/183:12 pm -
2 stops58h 08m
Fri 2/51:35 pm -
2 stops52h 11m
Deal found 10/25![United Airlines logo]()
$760
This Justfly.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1911:35 am -
2 stops18h 45m
Sun 3/2812:20 pm -
2 stops17h 23m
Deal found 10/28![British Airways logo]()
$961
This Finnair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1211:05 am -
1 stop20h 30m
Mon 4/261:35 pm -
1 stop16h 22m
Deal found 10/30![Multiple Airlines logo]()
$815
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/48:12 am -
1 stop20h 33m
Mon 1/189:20 am -
1 stop16h 59m
Deal found 10/26![Delta logo]()
$824
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:18 pm -
2 stops18h 12m
Fri 1/151:50 pm -
3 stops33h 29m
Deal found 10/26![United Airlines logo]()
$762
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/26:34 pm -
2 stops38h 41m
Sat 1/164:15 pm -
2 stops36h 31m
Deal found 10/27![Lufthansa logo]()
$992
This Iberia deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/19:41 am -
2 stops28h 24m
Fri 2/59:15 am -
2 stops21h 15m
Deal found 10/25![Iberia logo]()
$1,099
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:05 pm -
2 stops14h 15m
Sun 12/209:20 am -
2 stops21h 08m
Deal found 10/29![Delta logo]()
$827
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
2 stops20h 00m
Wed 12/166:50 am -
2 stops23h 32m
Deal found 10/25![United Airlines logo]()
$762
This United deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop24h 15m
Thu 11/261:35 pm -
2 stops32h 51m
Deal found 10/24![Multiple Airlines logo]()
$854
This British Airways deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:01 am -
2 stops22h 44m
Fri 2/59:15 am -
2 stops19h 34m
Deal found 10/27![British Airways logo]()
$1,070
This KLM deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/152:17 pm -
2 stops22h 08m
Fri 12/2510:45 am -
2 stops29h 22m
Deal found 10/28![KLM logo]()
$975
Last-minute flights from Missouri to SpainDiscover last-minute flight deals from Missouri to Spain. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Spain. Data last updated October 30, 2026 and is based on user searches.
This Sembo deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sembo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:53 am -
2 stops14h 07m
Wed 12/96:05 am -
1 stop14h 40m
Deal found 10/25![Multiple Airlines logo]()
$746
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:49 am -
2 stops16h 11m
Tue 12/810:30 am -
2 stops18h 17m
Deal found 10/26![United Airlines logo]()
$755
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:11 am -
2 stops23h 39m
Wed 12/96:05 am -
2 stops18h 48m
Deal found 10/27![Lufthansa logo]()
$753
This eDestinos deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/243:30 pm -
1 stop11h 15m
Wed 12/912:20 pm -
1 stop35h 15m
Deal found 10/27![Virgin Atlantic logo]()
$759
This KLM deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:40 am -
1 stop15h 05m
Wed 12/96:05 am -
2 stops17h 30m
Deal found 10/27![KLM logo]()
$761
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:00 am -
1 stop24h 15m
Wed 12/91:35 pm -
2 stops50h 21m
Deal found 10/26![United Airlines logo]()
$756
This Virgin Atlantic deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/291:20 pm -
1 stop13h 25m
Wed 12/912:20 pm -
1 stop13h 49m
Deal found 10/26![Virgin Atlantic logo]()
$759
This KLM deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/291:20 pm -
1 stop12h 20m
Tue 12/156:00 am -
2 stops17h 34m
Deal found 10/25![KLM logo]()
$759
This Rumbo deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:30 pm -
2 stops32h 05m
Wed 12/1610:35 am -
2 stops20h 30m
Deal found 10/27![Virgin Atlantic logo]()
$735
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop20h 30m
Wed 12/166:05 am -
1 stop14h 40m
Deal found 10/28![United Airlines logo]()
$751
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:13 am -
2 stops17h 07m
Wed 12/169:20 am -
2 stops19h 18m
Deal found 10/28![Delta logo]()
$757
This Justfly.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:45 pm -
2 stops30h 15m
Tue 12/81:25 pm -
2 stops29h 58m
Deal found 10/26![Air Canada logo]()
$758
One-way flights from Missouri to SpainSearch for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Expedia deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/152:21 pm -
1 stop12h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![British Airways logo]()
$336
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/126:45 pm -
2 stops21h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Lufthansa logo]()
$343
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/159:40 am -
2 stops16h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![United Airlines logo]()
$346
This Mytrip deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/24:05 pm -
2 stops15h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$355
This Expedia deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/278:54 am -
1 stop14h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![British Airways logo]()
$356
This Air France deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2711:51 am -
2 stops13h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Air France logo]()
$362
This TravelUp deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/211:00 am -
1 stop14h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Lufthansa logo]()
$365
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/246:30 am -
1 stop19h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/56:45 pm -
2 stops55h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$368
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/276:30 am -
3 stops23h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$380
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/222:23 pm -
2 stops19h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Iberia logo]()
$381
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/51:05 pm -
1 stop12h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Iberia logo]()
$385
Find flight deals from Missouri to Spain
Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated October 30, 2026.
Round-trip from | $725 (eDestinos) |
|---|---|
One-way from | $336 (Expedia) |
Popular in | June |
Cheapest in | April |
Average price | $977 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisBarcelona
STL Lambert-St Louis - BCN Barcelona-El Prat
STLBCN
Lambert-St Louis
Tue 2/2
4:05 pm-2:05 pm
2 stops15h 00m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$355
St. LouisBarcelona
STL Lambert-St Louis - BCN Barcelona-El Prat
STLBCN
Lambert-St Louis
Tue 4/27
6:30 am-1:05 pm
3 stops23h 35m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$380
St. LouisSeville
STL Lambert-St Louis - SVQ Sevilla
STLSVQ
Lambert-St Louis
Mon 2/22
2:23 pm-5:15 pm
2 stops19h 52m
Sevilla
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$381
St. LouisBarcelona
STL Lambert-St Louis - BCN Barcelona-El Prat
STLBCN
Lambert-St Louis
Tue 2/2
1:17 pm-9:35 am
3 stops37h 18m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$387
Kansas CityMálaga
MCI Kansas City - AGP Malaga
MCIAGP
Kansas City
Sun 4/4
10:00 am-3:50 pm
2 stops22h 50m
Malaga
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$391
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Thu 11/12
12:14 pm-2:05 pm
3 stops42h 51m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$406
St. LouisSeville
STL Lambert-St Louis - SVQ Sevilla
STLSVQ
Lambert-St Louis
Sun 1/24
3:40 pm-8:45 am
2 stops34h 05m
Sevilla
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$409
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Fri 1/8
8:37 pm-9:10 am
3 stops53h 33m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$409
St. LouisBarcelona
STL Lambert-St Louis - BCN Barcelona-El Prat
STLBCN
Lambert-St Louis
Fri 2/26
2:21 pm-1:40 pm
2 stops16h 19m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$412
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Fri 1/22
8:31 pm-8:40 pm
3 stops41h 09m
Barcelona-El Prat
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$429
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
STL-BCN
STL-SVQ
MCI-MAD
STL-MAD
MCI-BCN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Spain
USMO-ES0
STL-BCN
STL-SVQ
MCI-MAD
STL-MAD
What is the cheapest month to book a flight from Missouri to Spain?
Currently, April is the cheapest month in which you can book a flight from Missouri to Spain (average of $669). Flying from Missouri to Spain in June is currently the most expensive (average of $1,504). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Missouri to Spain?
Booking 71 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Top regions
Alternative routes for Missouri to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Spain by cabin class
Find flights from Missouri to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Spain flights
Browse other Missouri and Spain flight options. Last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Spain
Find the right flight back to Missouri after your stay in Spain
Missouri to Spain flights
Consider these flights traveling from Missouri to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 8 airlines flying from Missouri to Spain
Discover the top 8 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$382 | Average$631 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$449 | Average$955 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$480 | Average$1,251 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$485 | Average$984 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$488 | Average$863 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$488 | Average$982 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$490 | Average$1,011 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$648 | Average$1,135 | FlexibilityNo cancel fee | On-time67% |