$341+ Cheap flights from Missouri to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
May 19 — May 261
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:23 am
MCI
- AGP
2 stops18h 12m
United Airlines
Tue 9/89:35 am
AGP
- MCI
2 stops36h 29m
United Airlines
Deal found 4/15![United Airlines logo]()
$644
This Ovago deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:20 am
MCI
- AGP
2 stops18h 05m
Multiple Airlines
Tue 9/89:35 am
AGP
- MCI
1 stop21h 22m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$694
This Gotogate deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:55 am
STL
- MAD
1 stop17h 55m
Multiple Airlines
Fri 10/306:00 am
MAD
- STL
1 stop14h 55m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$710
This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 pm
STL
- MAD
1 stop13h 00m
British Airways
Wed 10/2112:10 pm
MAD
- STL
1 stop14h 20m
British Airways
Deal found 4/17![British Airways logo]()
$721
This oojo deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:35 pm
STL
- MAD
1 stop13h 00m
British Airways
Fri 10/301:15 pm
MAD
- STL
1 stop16h 26m
British Airways
Deal found 4/14![British Airways logo]()
$723
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:40 am
STL
- MAD
2 stops18h 25m
United Airlines
Wed 10/211:30 pm
MAD
- STL
2 stops33h 56m
United Airlines
Deal found 4/16![United Airlines logo]()
$725
This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:15 pm
STL
- MAD
2 stops15h 35m
Lufthansa
Wed 11/116:00 am
MAD
- STL
1 stop14h 55m
Lufthansa
Deal found 4/17![Lufthansa logo]()
$726
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:35 pm
STL
- MAD
1 stop12h 55m
American Airlines
Fri 10/93:55 pm
MAD
- STL
1 stop14h 46m
American Airlines
Deal found 4/15![American Airlines logo]()
$728
This Gotogate deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:49 pm
STL
- MAD
2 stops29h 01m
Air Canada
Wed 10/141:30 pm
MAD
- STL
2 stops33h 08m
Air Canada
Deal found 4/14![Air Canada logo]()
$729
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:15 pm
STL
- MAD
2 stops28h 45m
United Airlines
Fri 11/276:00 am
MAD
- STL
1 stop14h 55m
United Airlines
Deal found 4/17![United Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:01 am
STL
- MAD
2 stops19h 04m
United Airlines
Fri 10/306:00 am
MAD
- STL
1 stop14h 55m
United Airlines
Deal found 4/16![United Airlines logo]()
$731
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:00 am
MCI
- MAD
2 stops27h 40m
SWISS
Tue 10/2010:05 am
MAD
- MCI
2 stops18h 29m
SWISS
Deal found 4/14![SWISS logo]()
$733
Best flights from Missouri to SpainDiscover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:23 am
MCI
- AGP
2 stops18h 12m
United Airlines
Tue 9/89:35 am
AGP
- MCI
2 stops36h 29m
United Airlines
Deal found 4/15![United Airlines logo]()
$644
This KLM deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:13 pm
MCI
- MAD
1 stop16h 02m
Multiple Airlines
Tue 10/2012:45 pm
MAD
- MCI
1 stop13h 24m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$760
This KLM deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:10 am
MCI
- MAD
1 stop13h 10m
KLM
Thu 10/159:50 am
MAD
- MCI
1 stop14h 42m
KLM
Deal found 4/14![KLM logo]()
$760
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:59 am
MCI
- MAD
2 stops16h 11m
Delta
Thu 10/159:50 am
MAD
- MCI
1 stop13h 36m
Delta
Deal found 4/14![Delta logo]()
$764
This eDestinos deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:26 pm
SGF
- MAD
1 stop13h 49m
Virgin Atlantic
Thu 8/209:50 am
MAD
- SGF
1 stop19h 39m
Virgin Atlantic
Deal found 4/17![Virgin Atlantic logo]()
$772
This KAYAK deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:00 pm
MCI
- AGP
2 stops22h 55m
Lufthansa
Tue 9/89:35 am
AGP
- MCI
1 stop21h 22m
Lufthansa
Deal found 4/14![Lufthansa logo]()
$772
This KAYAK deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:45 am
MCI
- AGP
2 stops25h 05m
SWISS
Tue 9/81:15 pm
AGP
- MCI
2 stops35h 19m
SWISS
Deal found 4/14![SWISS logo]()
$823
This eDestinos deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:30 pm
SGF
- MAD
2 stops37h 25m
Scandinavian Airlines
Fri 9/116:30 pm
MAD
- SGF
2 stops34h 59m
Scandinavian Airlines
Deal found 4/18![Scandinavian Airlines logo]()
$891
This oojo deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:28 pm
MCI
- VLC
2 stops42h 07m
British Airways
Sat 5/236:20 pm
VLC
- MCI
2 stops29h 18m
British Airways
Deal found 4/17![British Airways logo]()
$963
This Turkish Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:45 am
STL
- MAD
2 stops22h 50m
Turkish Airlines
Thu 5/712:00 pm
MAD
- STL
2 stops40h 13m
Turkish Airlines
Deal found 4/14![Turkish Airlines logo]()
$978
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:21 am
SGF
- MAD
1 stop14h 59m
American Airlines
Thu 5/211:35 pm
MAD
- SGF
1 stop16h 05m
American Airlines
Deal found 4/15![American Airlines logo]()
$1,066
This Travelocity deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/411:16 am
MCI
- IBZ
2 stops29h 34m
Iberia
Sun 7/126:00 pm
IBZ
- MCI
2 stops33h 48m
Iberia
Deal found 4/14![Iberia logo]()
$1,096
This Finnair deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:11 pm
STL
- MAD
1 stop13h 19m
Finnair
Sun 10/411:00 pm
MAD
- STL
2 stops51h 30m
Finnair
Deal found 4/18![Finnair logo]()
$1,170
This Air France deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:37 pm
MCI
- VLC
2 stops16h 13m
Air France
Mon 6/296:35 am
VLC
- MCI
2 stops19h 08m
Air France
Deal found 4/17![Air France logo]()
$1,175
This oojo deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
MCI
- AGP
2 stops23h 50m
Aer Lingus
Mon 5/259:00 pm
AGP
- MCI
2 stops34h 23m
Aer Lingus
Deal found 4/18![Aer Lingus logo]()
$1,333
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:00 am
MCI
- MAD
2 stops17h 05m
United Airlines
Tue 10/2712:35 pm
MAD
- MCI
2 stops33h 49m
United Airlines
Deal found 4/15![United Airlines logo]()
$744
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:59 am
MCI
- MAD
1 stop16h 56m
Delta
Tue 10/2710:00 am
MAD
- MCI
2 stops19h 58m
Delta
Deal found 4/18![Delta logo]()
$765
This Air Canada deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:50 am
MCI
- AGP
3 stops19h 35m
Air Canada
Tue 9/810:30 am
AGP
- MCI
3 stops29h 37m
Air Canada
Deal found 4/15![Air Canada logo]()
$1,539
This KLM deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:10 am
MCI
- MAD
1 stop13h 10m
Multiple Airlines
Tue 10/2012:45 pm
MAD
- MCI
1 stop13h 24m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$810
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
MCI
- MAD
2 stops20h 00m
United Airlines
Tue 10/201:30 pm
MAD
- MCI
2 stops28h 03m
United Airlines
Deal found 4/16![United Airlines logo]()
$749
This KLM deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
SGF
- MAD
2 stops17h 20m
KLM
Thu 8/209:50 am
MAD
- SGF
1 stop19h 39m
KLM
Deal found 4/17![KLM logo]()
$877
This eDestinos deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:30 pm
SGF
- MAD
1 stop13h 45m
Virgin Atlantic
Fri 9/119:50 am
MAD
- SGF
1 stop19h 39m
Virgin Atlantic
Deal found 4/18![Virgin Atlantic logo]()
$883
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:26 pm
MCI
- MAD
1 stop11h 49m
Delta
Tue 10/2012:45 pm
MAD
- MCI
2 stops18h 13m
Delta
Deal found 4/16![Delta logo]()
$815
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am
MCI
- MAD
2 stops20h 50m
United Airlines
Tue 10/61:30 pm
MAD
- MCI
2 stops34h 31m
United Airlines
Deal found 4/18![United Airlines logo]()
$753
This FlightHub deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 pm
SGF
- MAD
2 stops18h 10m
British Airways
Thu 5/211:35 pm
MAD
- SGF
1 stop16h 05m
British Airways
Deal found 4/14![British Airways logo]()
$969
This KLM deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:42 pm
STL
- VLC
2 stops17h 33m
Multiple Airlines
Fri 9/46:35 am
VLC
- STL
2 stops17h 14m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$978
This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:30 pm
STL
- VLC
1 stop19h 00m
Lufthansa
Fri 9/46:05 am
VLC
- STL
1 stop14h 20m
Lufthansa
Deal found 4/17![Lufthansa logo]()
$1,121
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:59 am
MCI
- BCN
2 stops16h 01m
Delta
Sun 9/63:15 pm
BCN
- MCI
1 stop25h 16m
Delta
Deal found 4/15![Delta logo]()
$930
This KLM deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:40 pm
STL
- BCN
1 stop14h 10m
KLM
Fri 8/1411:30 am
BCN
- STL
1 stop34h 08m
KLM
Deal found 4/14![KLM logo]()
$1,027
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:22 am
MCI
- BCN
2 stops40h 38m
United Airlines
Sat 10/1712:15 pm
BCN
- MCI
2 stops29h 18m
United Airlines
Deal found 4/18![United Airlines logo]()
$868
Last-minute flights from Missouri to SpainDiscover last-minute flight deals from Missouri to Spain. Data last updated April 19, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Spain. Data last updated April 19, 2026 and is based on user searches.
This Finnair deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:27 pm
STL
- MAD
1 stop12h 53m
Multiple Airlines
Thu 4/301:35 pm
MAD
- STL
1 stop15h 42m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$924
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:27 pm
STL
- MAD
1 stop33h 28m
Delta
Thu 4/306:00 am
MAD
- STL
2 stops17h 50m
Delta
Deal found 4/15![Delta logo]()
$926
This Finnair deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:27 pm
STL
- MAD
1 stop18h 58m
Multiple Airlines
Tue 4/2111:45 am
MAD
- STL
1 stop17h 34m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$939
This Expedia deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:03 pm
STL
- MAD
1 stop29h 17m
Iberia
Fri 5/111:45 am
MAD
- STL
1 stop14h 48m
Iberia
Deal found 4/14![Iberia logo]()
$873
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:30 am
STL
- MAD
2 stops18h 35m
United Airlines
Fri 5/110:50 am
MAD
- STL
1 stop20h 07m
United Airlines
Deal found 4/14![United Airlines logo]()
$923
This Rumbo deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:50 pm
SGF
- MAD
2 stops21h 50m
Lufthansa
Tue 4/285:55 am
MAD
- SGF
2 stops18h 29m
Lufthansa
Deal found 4/15![Lufthansa logo]()
$909
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:54 am
SGF
- MAD
1 stop16h 11m
American Airlines
Tue 4/283:55 pm
MAD
- SGF
1 stop24h 29m
American Airlines
Deal found 4/15![American Airlines logo]()
$910
This Expedia deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:33 pm
STL
- IBZ
2 stops23h 27m
Iberia
Mon 4/277:20 pm
IBZ
- STL
2 stops33h 59m
Iberia
Deal found 4/15![Iberia logo]()
$915
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:10 am
MCI
- AGP
2 stops20h 35m
Delta
Mon 4/275:25 pm
AGP
- MCI
2 stops29h 41m
Delta
Deal found 4/13![Delta logo]()
$757
This oojo deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:29 pm
STL
- MAD
1 stop13h 06m
British Airways
Thu 4/3010:25 am
MAD
- STL
1 stop14h 39m
British Airways
Deal found 4/17![British Airways logo]()
$927
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:45 am
STL
- MAD
1 stop16h 20m
United Airlines
Fri 5/1512:45 pm
MAD
- STL
2 stops32h 47m
United Airlines
Deal found 4/16![United Airlines logo]()
$948
This Cheapflightsfares deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:00 am
MCI
- MAD
2 stops27h 40m
SWISS
Wed 5/1310:05 am
MAD
- MCI
2 stops18h 59m
SWISS
Deal found 4/15![SWISS logo]()
$944
One-way flights from Missouri to SpainSearch for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
This oojo deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:35 am
SGF
- MAD
2 stops22h 15m
British Airways
Deal found 4/15![British Airways logo]()
$341
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:34 am
STL
- MAD
1 stop14h 56m
American Airlines
Deal found 4/15![American Airlines logo]()
$341
This Gotogate deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:40 pm
STL
- MAD
2 stops33h 10m
Air Canada
Deal found 4/15![Air Canada logo]()
$348
This Cheapflightsfares deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:40 pm
STL
- BCN
1 stop14h 55m
British Airways
Deal found 4/18![British Airways logo]()
$351
This oojo deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:08 am
STL
- BCN
2 stops21h 07m
British Airways
Deal found 4/18![British Airways logo]()
$352
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
SGF
- MAD
2 stops19h 05m
United Airlines
Deal found 4/15![United Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:45 am
MCI
- BCN
2 stops28h 25m
SWISS
Deal found 4/17![SWISS logo]()
$356
This oojo deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:52 pm
SGF
- MAD
1 stop34h 13m
British Airways
Deal found 4/15![British Airways logo]()
$363
This oojo deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:43 pm
MCI
- BCN
2 stops17h 32m
British Airways
Deal found 4/16![British Airways logo]()
$365
This oojo deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:00 pm
STL
- BCN
1 stop31h 35m
British Airways
Deal found 4/18![British Airways logo]()
$372
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:50 am
SGF
- MAD
2 stops31h 00m
United Airlines
Deal found 4/15![United Airlines logo]()
$373
This TravelUp deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:20 am
MCI
- BCN
1 stop18h 55m
Lufthansa
Deal found 4/17![Lufthansa logo]()
$373
Find flight deals from Missouri to Spain
Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated April 19, 2026.
Round-trip from | $644 (United Airlines) |
|---|---|
One-way from | $341 (oojo) |
Popular in | June |
Cheapest in | January |
Average price | $634 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityMálaga
MCI - AGP
MCIAGP
Kansas City
Tue 8/18
6:23 am-7:35 am
2 stops18h 12m
Malaga
Tue 9/8
9:35 am-3:04 pm
2 stops36h 29m
$644
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/13
8:00 am-8:05 am
2 stops17h 05m
Madrid Barajas
Tue 10/27
12:35 pm-4:24 pm
2 stops33h 49m
$744
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/6
6:00 am-9:00 am
2 stops20h 00m
Madrid Barajas
Tue 10/20
1:30 pm-10:33 am
2 stops28h 03m
$749
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Wed 9/23
6:00 am-9:50 am
2 stops20h 50m
Madrid Barajas
Tue 10/6
1:30 pm-5:01 pm
2 stops34h 31m
$753
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/6
1:13 pm-12:15 pm
1 stop16h 02m
Madrid Barajas
Tue 10/20
12:45 pm-7:09 pm
1 stop13h 24m
$760
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Wed 10/7
10:10 am-6:20 am
1 stop13h 10m
Madrid Barajas
Thu 10/15
9:50 am-5:32 pm
1 stop14h 42m
$760
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Wed 10/7
9:59 am-9:10 am
2 stops16h 11m
Madrid Barajas
Thu 10/15
9:50 am-4:26 pm
1 stop13h 36m
$764
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/13
9:59 am-9:55 am
1 stop16h 56m
Madrid Barajas
Tue 10/27
10:00 am-11:58 pm
2 stops19h 58m
$765
SpringfieldMadrid
SGF - MAD
SGFMAD
Springfield-Branson
Wed 8/5
3:26 pm-12:15 pm
1 stop13h 49m
Madrid Barajas
Thu 8/20
9:50 am-10:29 pm
1 stop19h 39m
$772
Kansas CityMálaga
MCI - AGP
MCIAGP
Kansas City
Tue 9/1
12:00 pm-5:55 pm
2 stops22h 55m
Malaga
Tue 9/8
9:35 am-11:57 pm
1 stop21h 22m
$772
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
SGF-MAD
MCI-BCN
MCI-MAD
STL-BCN
STL-MAD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Spain
USMO-ES0
SGF-MAD
MCI-BCN
MCI-MAD
STL-BCN
What is the cheapest month to book a flight from Missouri to Spain?
Currently, March is the cheapest month in which you can book a flight from Missouri to Spain (average of $405). Flying from Missouri to Spain in June is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
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Top destinations
Top regions
Alternative routes for Missouri to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Spain by cabin class
Find flights from Missouri to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Spain flights
Browse other Missouri and Spain flight options. Last updated on April 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Spain
Find the right flight back to Missouri after your stay in Spain
Missouri to Spain flights
Consider these flights traveling from Missouri to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 10 airlines flying from Missouri to Spain
Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$433 | Average$747 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$437 | Average$719 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$457 | Average$753 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$461 | Average$781 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$480 | Average$1,104 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$485 | Average$837 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$487 | Average$807 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$488 | Average$782 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$490 | Average$807 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$576 | Average$995 | FlexibilityNo cancel fee | On-time67% |