$307+ Cheap flights from Missouri to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — MAD
Jun 28 — Jul 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Spain
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 29, 2026.
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 29, 2026.
This eDestinos deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:26 pm
MCI
- MAD
2 stops15h 14m
Iberia
Wed 10/143:25 pm
MAD
- MCI
1 stop13h 30m
Iberia
Deal found 5/28![Iberia logo]()
$666
This eDestinos deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:06 am
SGF
- MAD
2 stops20h 49m
Virgin Atlantic
Wed 10/149:50 am
MAD
- SGF
1 stop15h 20m
Virgin Atlantic
Deal found 5/28![Virgin Atlantic logo]()
$699
This oojo deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 pm
STL
- MAD
1 stop15h 30m
British Airways
Wed 10/213:25 pm
MAD
- STL
1 stop15h 16m
British Airways
Deal found 5/27![British Airways logo]()
$719
This oojo deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:35 pm
STL
- VLC
1 stop16h 00m
British Airways
Wed 10/2111:25 am
VLC
- STL
1 stop15h 05m
British Airways
Deal found 5/27![British Airways logo]()
$726
This British Airways deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:35 pm
STL
- MAD
1 stop14h 40m
British Airways
Fri 10/93:55 pm
MAD
- STL
1 stop14h 46m
British Airways
Deal found 5/29![British Airways logo]()
$728
This oojo deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/133:40 pm
STL
- VLC
1 stop18h 50m
Lufthansa
Fri 12/186:10 am
VLC
- STL
1 stop14h 35m
Lufthansa
Deal found 5/28![Lufthansa logo]()
$729
This Orbitz deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:55 am
STL
- MAD
1 stop16h 55m
Air Canada
Fri 10/912:45 pm
MAD
- STL
1 stop12h 56m
Air Canada
Deal found 5/24![Air Canada logo]()
$729
This oojo deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:30 pm
SGF
- BCN
2 stops19h 50m
Scandinavian Airlines
Tue 11/1712:25 pm
BCN
- SGF
2 stops41h 07m
Scandinavian Airlines
Deal found 5/29![Scandinavian Airlines logo]()
$731
This British Airways deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:45 pm
STL
- MAD
2 stops14h 55m
British Airways
Fri 10/93:55 pm
MAD
- STL
1 stop14h 46m
British Airways
Deal found 5/26![British Airways logo]()
$732
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
MCI
- MAD
1 stop20h 00m
United Airlines
Tue 10/2712:35 pm
MAD
- MCI
2 stops27h 58m
United Airlines
Deal found 5/29![United Airlines logo]()
$740
This Expedia deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:29 pm
STL
- MAD
1 stop32h 51m
Iberia
Tue 10/611:45 am
MAD
- STL
1 stop15h 23m
Iberia
Deal found 5/26![Iberia logo]()
$741
This FlightHub deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:15 pm
STL
- VLC
2 stops19h 40m
Multiple Airlines
Fri 12/186:10 am
VLC
- STL
1 stop14h 35m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$742
Best flights from Missouri to SpainDiscover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 29, 2026.
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 29, 2026.
This oojo deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:30 pm
SGF
- BCN
2 stops19h 50m
Scandinavian Airlines
Tue 11/1712:25 pm
BCN
- SGF
2 stops41h 07m
Scandinavian Airlines
Deal found 5/29![Scandinavian Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:39 pm
MCI
- MAD
2 stops29h 11m
United Airlines
Fri 10/2312:45 pm
MAD
- MCI
2 stops32h 33m
United Airlines
Deal found 5/27![United Airlines logo]()
$743
This KLM deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:51 am
STL
- VLC
2 stops16h 44m
Multiple Airlines
Wed 10/216:35 am
VLC
- STL
2 stops17h 31m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$745
This British Airways deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:19 pm
SGF
- MAD
2 stops15h 16m
British Airways
Wed 11/181:00 pm
MAD
- SGF
1 stop12h 47m
British Airways
Deal found 5/26![British Airways logo]()
$756
This Virgin Atlantic deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
SGF
- MAD
2 stops19h 00m
Virgin Atlantic
Wed 11/1810:00 am
MAD
- SGF
2 stops19h 32m
Virgin Atlantic
Deal found 5/26![Virgin Atlantic logo]()
$764
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:45 am
STL
- MAD
2 stops20h 10m
Delta
Wed 10/2112:45 pm
MAD
- STL
2 stops17h 54m
Delta
Deal found 5/25![Delta logo]()
$768
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:18 pm
STL
- VLC
2 stops17h 07m
American Airlines
Wed 10/711:25 am
VLC
- STL
1 stop15h 05m
American Airlines
Deal found 5/27![American Airlines logo]()
$784
This Expedia deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:19 pm
SGF
- BCN
2 stops36h 06m
Iberia
Tue 11/1710:40 am
BCN
- SGF
1 stop17h 06m
Iberia
Deal found 5/27![Iberia logo]()
$796
This Air France deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:59 am
MCI
- AGP
2 stops19h 21m
Air France
Sat 11/286:05 am
AGP
- MCI
2 stops23h 21m
Air France
Deal found 5/26![Air France logo]()
$911
This KLM deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:25 am
MCI
- BCN
1 stop19h 25m
KLM
Sun 9/63:15 pm
BCN
- MCI
1 stop34h 28m
KLM
Deal found 5/28![KLM logo]()
$963
This Gurufare deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/43:30 pm
STL
- IBZ
1 stop13h 15m
Lufthansa
Mon 8/1012:50 pm
IBZ
- STL
2 stops33h 48m
Lufthansa
Deal found 5/29![Lufthansa logo]()
$1,147
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:00 pm
MCI
- MAD
1 stop13h 05m
United Airlines
Tue 10/201:30 pm
MAD
- MCI
2 stops27h 56m
United Airlines
Deal found 5/26![United Airlines logo]()
$744
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:47 pm
STL
- VLC
2 stops14h 18m
American Airlines
Wed 11/46:45 am
VLC
- STL
2 stops19h 42m
American Airlines
Deal found 5/26![American Airlines logo]()
$789
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:52 pm
STL
- VLC
2 stops16h 13m
Multiple Airlines
Wed 11/46:05 am
VLC
- STL
2 stops20h 24m
Multiple Airlines
Deal found 5/28![Multiple Airlines logo]()
$789
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:00 am
STL
- VLC
2 stops18h 35m
Delta
Wed 10/76:35 am
VLC
- STL
2 stops17h 31m
Delta
Deal found 5/28![Delta logo]()
$795
This British Airways deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 pm
SGF
- BCN
2 stops16h 55m
British Airways
Tue 11/1710:40 am
BCN
- SGF
1 stop17h 06m
British Airways
Deal found 5/28![British Airways logo]()
$797
This Air Canada deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:30 am
MCI
- AGP
3 stops21h 40m
Air Canada
Sat 11/286:00 am
AGP
- MCI
3 stops33h 51m
Air Canada
Deal found 5/26![Air Canada logo]()
$1,623
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:00 pm
MCI
- MAD
1 stop13h 05m
United Airlines
Fri 10/306:00 am
MAD
- MCI
2 stops22h 07m
United Airlines
Deal found 5/28![United Airlines logo]()
$760
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:26 pm
MCI
- AGP
2 stops19h 14m
Delta
Tue 10/205:25 pm
AGP
- MCI
2 stops36h 52m
Delta
Deal found 5/27![Delta logo]()
$797
This British Airways deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:34 pm
STL
- VLC
2 stops18h 26m
Multiple Airlines
Wed 10/711:25 am
VLC
- STL
1 stop15h 05m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$833
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
MCI
- MAD
2 stops19h 05m
United Airlines
Tue 10/2711:15 am
MAD
- MCI
2 stops27h 36m
United Airlines
Deal found 5/29![United Airlines logo]()
$764
This British Airways deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:20 pm
STL
- MAD
1 stop13h 00m
British Airways
Mon 11/912:00 pm
MAD
- STL
2 stops17h 29m
British Airways
Deal found 5/25![British Airways logo]()
$851
This KLM deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:38 pm
MCI
- BCN
1 stop14h 12m
KLM
Tue 7/213:15 pm
BCN
- MCI
1 stop34h 33m
KLM
Deal found 5/25![KLM logo]()
$966
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:13 pm
MCI
- AGP
2 stops20h 22m
Delta
Tue 10/205:25 pm
AGP
- MCI
2 stops36h 52m
Delta
Deal found 5/27![Delta logo]()
$804
This Scandinavian Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:40 pm
STL
- MAD
2 stops16h 30m
Scandinavian Airlines
Wed 11/186:00 am
MAD
- STL
3 stops24h 39m
Scandinavian Airlines
Deal found 5/25![Scandinavian Airlines logo]()
$973
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:53 pm
SGF
- MAD
1 stop29h 27m
Iberia
Tue 7/2112:20 pm
MAD
- SGF
1 stop18h 14m
Iberia
Deal found 5/25![Iberia logo]()
$975
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:20 pm
STL
- MAD
1 stop32h 55m
United Airlines
Fri 11/276:00 am
MAD
- STL
1 stop14h 45m
United Airlines
Deal found 5/27![United Airlines logo]()
$765
This KLM deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1611:38 am
SGF
- MAD
1 stop17h 37m
KLM
Mon 8/247:05 am
MAD
- SGF
2 stops22h 16m
KLM
Deal found 5/27![KLM logo]()
$974
This British Airways deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:10 pm
SGF
- BCN
2 stops15h 35m
British Airways
Sat 10/241:35 pm
BCN
- SGF
2 stops17h 23m
British Airways
Deal found 5/27![British Airways logo]()
$908
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 pm
STL
- VLC
2 stops22h 30m
Delta
Sat 12/126:00 am
VLC
- STL
2 stops21h 37m
Delta
Deal found 5/26![Delta logo]()
$847
Last-minute flights from Missouri to SpainDiscover last-minute flight deals from Missouri to Spain. Data last updated May 29, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Spain. Data last updated May 29, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:30 pm
MCI
- MAD
1 stop12h 35m
Lufthansa
Fri 6/511:15 am
MAD
- MCI
1 stop14h 48m
Lufthansa
Deal found 5/24![Lufthansa logo]()
$1,225
This Cheapflightsfares deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3112:30 pm
MCI
- MAD
1 stop12h 35m
Lufthansa
Fri 6/1210:50 am
MAD
- MCI
1 stop20h 09m
Lufthansa
Deal found 5/24![Lufthansa logo]()
$1,158
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:00 am
MCI
- MAD
2 stops17h 50m
United Airlines
Fri 6/121:30 pm
MAD
- MCI
2 stops35h 06m
United Airlines
Deal found 5/28![United Airlines logo]()
$1,175
This oojo deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:47 pm
MCI
- MAD
2 stops32h 48m
WestJet
Tue 6/1610:55 am
MAD
- MCI
2 stops29h 53m
WestJet
Deal found 5/24![WestJet logo]()
$1,234
This Mytrip deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:35 pm
STL
- MAD
2 stops35h 15m
Multiple Airlines
Mon 6/2212:45 pm
MAD
- STL
1 stop14h 40m
Multiple Airlines
Deal found 5/28![Multiple Airlines logo]()
$1,213
This oojo deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:25 am
MCI
- MAD
2 stops20h 10m
WestJet
Thu 6/2510:55 am
MAD
- MCI
2 stops29h 53m
WestJet
Deal found 5/26![WestJet logo]()
$1,183
This Mytrip deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:22 am
STL
- MAD
2 stops19h 13m
Multiple Airlines
Wed 6/2410:25 pm
MAD
- STL
3 stops28h 42m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$948
This Kiwi.com deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:30 am
STL
- MAD
1 stop21h 50m
Multiple Airlines
Tue 7/710:55 am
MAD
- STL
2 stops16h 42m
Multiple Airlines
Deal found 5/28![Multiple Airlines logo]()
$1,206
This Cheapflightsfares deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/221:13 pm
STL
- MAD
2 stops17h 57m
Lufthansa
Wed 7/15:55 am
MAD
- STL
1 stop14h 30m
Lufthansa
Deal found 5/25![Lufthansa logo]()
$1,236
This Kiwi.com deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:30 am
STL
- MAD
1 stop22h 40m
Multiple Airlines
Tue 7/710:55 am
MAD
- STL
2 stops16h 42m
Multiple Airlines
Deal found 5/28![Multiple Airlines logo]()
$1,232
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:30 am
STL
- MAD
1 stop22h 40m
Multiple Airlines
Tue 7/710:55 am
MAD
- STL
2 stops16h 42m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$1,225
This Cheapflightsfares deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:55 pm
STL
- MAD
1 stop12h 10m
Lufthansa
Tue 7/75:55 am
MAD
- STL
1 stop14h 30m
Lufthansa
Deal found 5/25![Lufthansa logo]()
$1,229
One-way flights from Missouri to SpainSearch for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated May 29, 2026.
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated May 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:34 pm
STL
- BCN
2 stops40h 26m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$307
This oojo deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:47 am
STL
- BCN
2 stops21h 53m
British Airways
Deal found 5/29![British Airways logo]()
$349
This oojo deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:39 am
STL
- BCN
1 stop14h 11m
British Airways
Deal found 5/28![British Airways logo]()
$357
This oojo deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:35 pm
MCI
- BCN
2 stops15h 00m
British Airways
Deal found 5/26![British Airways logo]()
$360
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:14 am
STL
- BCN
1 stop16h 36m
American Airlines
Deal found 5/29![American Airlines logo]()
$362
This eDestinos deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am
STL
- BCN
1 stop18h 50m
Iberia
Deal found 5/26![Iberia logo]()
$365
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:31 pm
MCI
- BCN
2 stops13h 49m
American Airlines
Deal found 5/28![American Airlines logo]()
$372
This Iberia deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:33 am
STL
- BCN
1 stop25h 32m
Multiple Airlines
Deal found 5/27![Multiple Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:09 am
MCI
- BCN
1 stop18h 26m
American Airlines
Deal found 5/28![American Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 am
STL
- BCN
3 stops28h 10m
United Airlines
Deal found 5/28![United Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:59 pm
STL
- MAD
2 stops36h 36m
WestJet
Deal found 5/25![WestJet logo]()
$400
This Air Canada deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am
MCI
- BCN
3 stops18h 35m
Air Canada
Deal found 5/28![Air Canada logo]()
$403
Find flight deals from Missouri to Spain
Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated May 29, 2026.
Round-trip from | $666 (eDestinos) |
|---|---|
One-way from | $307 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $898 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 29, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SpringfieldBarcelona
SGF - BCN
SGFBCN
Springfield-Branson
Mon 11/9
3:30 pm-6:20 pm
2 stops19h 50m
Barcelona-El Prat
Tue 11/17
12:25 pm-10:32 pm
2 stops41h 07m
$731
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Sat 10/17
6:39 pm-6:50 am
2 stops29h 11m
Madrid Barajas
Fri 10/23
12:45 pm-2:18 pm
2 stops32h 33m
$743
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/6
12:00 pm-8:05 am
1 stop13h 05m
Madrid Barajas
Tue 10/20
1:30 pm-10:26 am
2 stops27h 56m
$744
St. LouisValencia
STL - VLC
STLVLC
Lambert-St Louis
Wed 10/14
11:51 am-11:35 am
2 stops16h 44m
Valencia
Wed 10/21
6:35 am-5:06 pm
2 stops17h 31m
$745
Quickest round-trip
SpringfieldMadrid
SGF - MAD
SGFMAD
Springfield-Branson
Wed 11/11
3:19 pm-1:35 pm
2 stops15h 16m
Madrid Barajas
Wed 11/18
1:00 pm-6:47 pm
1 stop12h 47m
$756
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/13
12:00 pm-8:05 am
1 stop13h 05m
Madrid Barajas
Fri 10/30
6:00 am-10:07 pm
2 stops22h 07m
$760
SpringfieldMadrid
SGF - MAD
SGFMAD
Springfield-Branson
Wed 11/11
6:00 am-8:00 am
2 stops19h 00m
Madrid Barajas
Wed 11/18
10:00 am-10:32 pm
2 stops19h 32m
$764
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/13
6:00 am-8:05 am
2 stops19h 05m
Madrid Barajas
Tue 10/27
11:15 am-8:51 am
2 stops27h 36m
$764
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Sun 11/22
5:20 pm-9:15 am
1 stop32h 55m
Madrid Barajas
Fri 11/27
6:00 am-1:45 pm
1 stop14h 45m
$765
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Wed 10/7
6:45 am-9:55 am
2 stops20h 10m
Madrid Barajas
Wed 10/21
12:45 pm-11:39 pm
2 stops17h 54m
$768
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
STL-MAD
MCI-MAD
SGF-MAD
STL-VLC
SGF-BCN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Spain
USMO-ES0
STL-MAD
MCI-MAD
SGF-MAD
STL-VLC
What is the cheapest month to book a flight from Missouri to Spain?
Currently, March is the cheapest month in which you can book a flight from Missouri to Spain (average of $405). Flying from Missouri to Spain in June is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Missouri to Spain?
Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Top regions
Alternative routes for Missouri to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Spain by cabin class
Find flights from Missouri to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Spain flights
Browse other Missouri and Spain flight options. Last updated on May 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Spain
Find the right flight back to Missouri after your stay in Spain
Missouri to Spain flights
Consider these flights traveling from Missouri to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 10 airlines flying from Missouri to Spain
Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$433 | Average$741 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$437 | Average$719 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$452 | Average$796 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$457 | Average$893 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$461 | Average$841 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$480 | Average$1,129 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$485 | Average$917 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$488 | Average$742 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$490 | Average$876 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$576 | Average$1,001 | FlexibilityNo cancel fee | On-time67% |