Spain

$336+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Jan 22 — Jan 291
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Cheap flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:46 pmMCI - BCN
2 stops16h 49mLufthansa
Wed 1/147:40 amBCN - MCI
2 stops21h 19mLufthansa
Deal found 12/22$660
This oojo deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:12 amMCI - BCN
2 stops25h 28mBritish Airways
Wed 1/1412:30 pmBCN - MCI
1 stop15h 36mBritish Airways
Deal found 12/22$673
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:05 pmSTL - MAD
2 stops20h 35mUnited Airlines
Wed 12/315:55 amMAD - STL
2 stops20h 23mUnited Airlines
Deal found 12/22$753
This oojo deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:35 pmSTL - MAD
2 stops36h 00mBritish Airways
Mon 1/128:50 pmMAD - STL
2 stops31h 25mBritish Airways
Deal found 12/22$771
This Expedia deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:04 amSTL - MAD
1 stop19h 21mIberia
Sun 1/115:40 pmMAD - STL
2 stops36h 04mIberia
Deal found 12/22$792
This Finnair deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:09 amSTL - MAD
1 stop13h 36mMultiple Airlines
Wed 12/311:00 pmMAD - STL
1 stop13h 30mMultiple Airlines
Deal found 12/22$799
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 amSTL - BCN
2 stops20h 05mUnited Airlines
Sun 12/2810:30 amBCN - STL
1 stop15h 52mUnited Airlines
Deal found 12/22$814
This oojo deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:01 pmSTL - MAD
2 stops39h 24mBritish Airways
Sun 1/116:05 pmMAD - STL
2 stops35h 39mBritish Airways
Deal found 12/22$814
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:00 amMCI - MAD
2 stops27h 40mUnited Airlines
Sun 12/285:55 amMAD - MCI
2 stops34h 23mUnited Airlines
Deal found 12/21$889
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:35 pmSTL - BCN
2 stops30h 45mUnited Airlines
Mon 12/2910:30 amBCN - STL
1 stop15h 52mUnited Airlines
Deal found 12/21$895
This Booking.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 amSTL - BCN
2 stops20h 05mMultiple Airlines
Sun 12/2811:00 amBCN - STL
1 stop19h 33mMultiple Airlines
Deal found 12/22$905
This oojo deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:06 pmSTL - BCN
2 stops22h 44mBritish Airways
Sun 12/289:20 pmBCN - STL
2 stops33h 24mBritish Airways
Deal found 12/22$908

Find flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated December 23, 2025.

Round-trip from

$436
(Kiwi.com)

One-way from

$336
(Air France)

Popular in

June

Cheapest in

February

Average price

$835
From Missouri to Spain
One-way flight from Missouri to Spain
Highest demand for flights based on searches. 24% potential increase in price ($283 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Tue 2/24

12:37 pm-8:20 am

1 stop12h 43m

Barcelona-El Prat

Tue 3/3

1:35 pm-10:36 am

2 stops28h 01m

$465

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 1/21

11:22 am-5:50 pm

2 stops23h 28m

Madrid Barajas

Sun 1/25

5:55 am-1:55 pm

1 stop15h 00m

$467

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Mon 1/19

8:05 am-9:35 am

2 stops18h 30m

Barcelona-El Prat

Mon 2/2

1:35 pm-5:41 pm

2 stops35h 06m

$468

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Sun 1/18

4:25 pm-9:35 am

2 stops34h 10m

Barcelona-El Prat

Sat 1/31

1:35 pm-7:47 pm

2 stops37h 12m

$468

SpringfieldBarcelona

SGF - BCN

SGFBCN

Springfield-Branson

Sat 2/21

3:15 pm-8:20 am

2 stops34h 05m

Barcelona-El Prat

Mon 3/2

1:35 pm-9:59 pm

2 stops39h 24m

$469

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Mon 1/19

5:45 am-9:15 am

2 stops20h 30m

Madrid Barajas

Mon 2/2

1:35 pm-2:27 pm

2 stops31h 52m

$473

Kansas CityMálaga

MCI - AGP

MCIAGP

Kansas City

Thu 1/22

5:49 pm-11:50 am

2 stops35h 01m

Malaga

Sun 1/25

1:10 pm-11:12 pm

2 stops41h 02m

$474

Kansas CityMálaga

MCI - AGP

MCIAGP

Kansas City

Tue 2/3

3:01 pm-11:00 am

2 stops36h 59m

Malaga

Tue 3/3

5:50 pm-6:47 pm

2 stops31h 57m

$474

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Mon 1/19

6:57 pm-8:40 am

1 stop30h 43m

Barcelona-El Prat

Sun 2/1

10:55 am-5:50 pm

1 stop13h 55m

$475

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Mon 1/19

12:35 pm-11:05 am

2 stops15h 30m

Barcelona-El Prat

Mon 2/2

6:50 am-7:56 pm

2 stops20h 06m

$476

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $449). Flying from Missouri to Spain in May is currently the most expensive (average of $820). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

It’s optimal to fly from Missouri to Spain in the morning. By choosing this option you can save up to 12% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from Missouri to Spain?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Spain. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Spain flight should consider departing on Wednesday mornings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Spain?

    United Airlines, Lufthansa, and British Airways can get you from Missouri to Spain in just under 12h 43m. Your travel time can differ by up to 22h 18m. There are 4803 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $322. However, be on the lookout for offers from United Airlines and Lufthansa, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $449). Flying from Missouri to Spain in May is currently the most expensive (average of $820). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Missouri to Spain

Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$433Average$763FlexibilityNo cancel feeOn-time75%
Virgin AtlanticCheapest$437Average$756FlexibilityNo cancel feeOn-time72%
British AirwaysCheapest$483Average$891FlexibilityNo cancel feeOn-time70%
DeltaCheapest$487Average$875FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$488Average$1,109FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$498Average$957FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$524Average$1,066FlexibilityNo cancel feeOn-time76%
Air FranceCheapest$533Average$752FlexibilityNo cancel feeOn-time77%
IberiaCheapest$578Average$1,010FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$624Average$1,086FlexibilityNo cancel feeOn-time67%

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