Spain

$307+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — MAD
Jun 28 — Jul 51
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Cheap flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 29, 2026.

This eDestinos deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:26 pm
MCI
-
MAD
2 stops15h 14m
Iberia
Wed 10/143:25 pm
MAD
-
MCI
1 stop13h 30m
Iberia
Deal found 5/28$666
This eDestinos deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:06 am
SGF
-
MAD
2 stops20h 49m
Virgin Atlantic
Wed 10/149:50 am
MAD
-
SGF
1 stop15h 20m
Virgin Atlantic
Deal found 5/28$699
This oojo deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 pm
STL
-
MAD
1 stop15h 30m
British Airways
Wed 10/213:25 pm
MAD
-
STL
1 stop15h 16m
British Airways
Deal found 5/27$719
This oojo deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:35 pm
STL
-
VLC
1 stop16h 00m
British Airways
Wed 10/2111:25 am
VLC
-
STL
1 stop15h 05m
British Airways
Deal found 5/27$726
This British Airways deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:35 pm
STL
-
MAD
1 stop14h 40m
British Airways
Fri 10/93:55 pm
MAD
-
STL
1 stop14h 46m
British Airways
Deal found 5/29$728
This oojo deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/133:40 pm
STL
-
VLC
1 stop18h 50m
Lufthansa
Fri 12/186:10 am
VLC
-
STL
1 stop14h 35m
Lufthansa
Deal found 5/28$729
This Orbitz deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:55 am
STL
-
MAD
1 stop16h 55m
Air Canada
Fri 10/912:45 pm
MAD
-
STL
1 stop12h 56m
Air Canada
Deal found 5/24$729
This oojo deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:30 pm
SGF
-
BCN
2 stops19h 50m
Scandinavian Airlines
Tue 11/1712:25 pm
BCN
-
SGF
2 stops41h 07m
Scandinavian Airlines
Deal found 5/29$731
This British Airways deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:45 pm
STL
-
MAD
2 stops14h 55m
British Airways
Fri 10/93:55 pm
MAD
-
STL
1 stop14h 46m
British Airways
Deal found 5/26$732
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
MCI
-
MAD
1 stop20h 00m
United Airlines
Tue 10/2712:35 pm
MAD
-
MCI
2 stops27h 58m
United Airlines
Deal found 5/29$740
This Expedia deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:29 pm
STL
-
MAD
1 stop32h 51m
Iberia
Tue 10/611:45 am
MAD
-
STL
1 stop15h 23m
Iberia
Deal found 5/26$741
This FlightHub deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:15 pm
STL
-
VLC
2 stops19h 40m
Multiple Airlines
Fri 12/186:10 am
VLC
-
STL
1 stop14h 35m
Multiple Airlines
Deal found 5/25$742

Find flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated May 29, 2026.

Round-trip from

$666
(eDestinos)

One-way from

$307
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$898
From Missouri to Spain
One-way flight from Missouri to Spain
Highest demand for flights based on searches. 27% potential increase in price ($318 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($60 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 29, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SpringfieldBarcelona

SGF - BCN

SGFBCN

Springfield-Branson

Mon 11/9

3:30 pm-6:20 pm

2 stops19h 50m

Barcelona-El Prat

Tue 11/17

12:25 pm-10:32 pm

2 stops41h 07m

$731

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Sat 10/17

6:39 pm-6:50 am

2 stops29h 11m

Madrid Barajas

Fri 10/23

12:45 pm-2:18 pm

2 stops32h 33m

$743

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/6

12:00 pm-8:05 am

1 stop13h 05m

Madrid Barajas

Tue 10/20

1:30 pm-10:26 am

2 stops27h 56m

$744

St. LouisValencia

STL - VLC

STLVLC

Lambert-St Louis

Wed 10/14

11:51 am-11:35 am

2 stops16h 44m

Valencia

Wed 10/21

6:35 am-5:06 pm

2 stops17h 31m

$745
Quickest round-trip

SpringfieldMadrid

SGF - MAD

SGFMAD

Springfield-Branson

Wed 11/11

3:19 pm-1:35 pm

2 stops15h 16m

Madrid Barajas

Wed 11/18

1:00 pm-6:47 pm

1 stop12h 47m

$756

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/13

12:00 pm-8:05 am

1 stop13h 05m

Madrid Barajas

Fri 10/30

6:00 am-10:07 pm

2 stops22h 07m

$760

SpringfieldMadrid

SGF - MAD

SGFMAD

Springfield-Branson

Wed 11/11

6:00 am-8:00 am

2 stops19h 00m

Madrid Barajas

Wed 11/18

10:00 am-10:32 pm

2 stops19h 32m

$764

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/13

6:00 am-8:05 am

2 stops19h 05m

Madrid Barajas

Tue 10/27

11:15 am-8:51 am

2 stops27h 36m

$764

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Sun 11/22

5:20 pm-9:15 am

1 stop32h 55m

Madrid Barajas

Fri 11/27

6:00 am-1:45 pm

1 stop14h 45m

$765

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 10/7

6:45 am-9:55 am

2 stops20h 10m

Madrid Barajas

Wed 10/21

12:45 pm-11:39 pm

2 stops17h 54m

$768

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/24

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, March is the cheapest month in which you can book a flight from Missouri to Spain (average of $405). Flying from Missouri to Spain in June is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from Missouri to Spain?

Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Spain?

    Scandinavian Airlines, United Airlines, and British Airways can get you from Missouri to Spain in just under 15h 16m. Your travel time can differ by up to 13h 55m. There are 4608 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $205. However, be on the lookout for offers from British Airways and Air Canada, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, March is the cheapest month in which you can book a flight from Missouri to Spain (average of $405). Flying from Missouri to Spain in June is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Missouri to Spain

Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$433Average$741FlexibilityNo cancel feeOn-time75%
Virgin AtlanticCheapest$437Average$719FlexibilityNo cancel feeOn-time72%
DeltaCheapest$452Average$796FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$457Average$893FlexibilityNo cancel feeOn-time77%
British AirwaysCheapest$461Average$841FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$480Average$1,129FlexibilityNo cancel feeOn-time76%
American AirlinesCheapest$485Average$917FlexibilityNo cancel feeOn-time71%
IberiaCheapest$488Average$742FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$490Average$876FlexibilityNo cancel feeOn-time69%
Air CanadaCheapest$576Average$1,001FlexibilityNo cancel feeOn-time67%

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