$316+ Cheap flights from Missouri to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Apr 25 — May 21
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Spain
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:23 am
MCI
- AGP
2 stops18h 12m
United Airlines
Wed 9/99:35 am
AGP
- MCI
1 stop14h 04m
United Airlines
Deal found 3/25![United Airlines logo]()
$482
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:00 am
MCI
- AGP
2 stops33h 05m
SWISS
Wed 4/296:30 am
AGP
- MCI
2 stops22h 34m
SWISS
Deal found 3/22![SWISS logo]()
$515
This Gurufare deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:36 pm
MCI
- AGP
2 stops16h 19m
Lufthansa
Wed 9/99:35 am
AGP
- MCI
1 stop21h 22m
Lufthansa
Deal found 3/24![Lufthansa logo]()
$527
This FlightHub deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 pm
MCI
- AGP
2 stops34h 40m
Multiple Airlines
Tue 4/286:30 am
AGP
- MCI
2 stops20h 15m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$532
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:00 pm
MCI
- AGP
2 stops15h 55m
Lufthansa
Wed 4/296:45 pm
AGP
- MCI
2 stops35h 46m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$537
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:45 pm
MCI
- AGP
2 stops17h 10m
Lufthansa
Thu 4/306:45 pm
AGP
- MCI
2 stops56h 05m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$544
This Gurufare deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:55 pm
MCI
- AGP
2 stops34h 50m
Multiple Airlines
Wed 9/96:30 am
AGP
- MCI
2 stops19h 47m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$550
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:05 pm
MCI
- AGP
2 stops18h 00m
Lufthansa
Fri 5/111:10 am
AGP
- MCI
2 stops19h 21m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$557
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 pm
MCI
- AGP
2 stops34h 40m
Lufthansa
Fri 5/111:10 am
AGP
- MCI
2 stops19h 21m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$563
This eDestinos deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:58 pm
STL
- MAD
1 stop10h 27m
Iberia
Wed 12/91:00 pm
MAD
- STL
1 stop16h 25m
Iberia
Deal found 3/23![Iberia logo]()
$633
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:30 pm
STL
- MAD
1 stop21h 20m
Lufthansa
Fri 10/306:00 am
MAD
- STL
1 stop14h 55m
Lufthansa
Deal found 3/23![Lufthansa logo]()
$655
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:50 pm
STL
- MAD
1 stop21h 20m
Lufthansa
Wed 11/118:30 am
MAD
- STL
2 stops21h 55m
Lufthansa
Deal found 3/23![Lufthansa logo]()
$664
Best flights from Missouri to SpainDiscover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:23 am
MCI
- AGP
2 stops18h 12m
United Airlines
Wed 9/99:35 am
AGP
- MCI
1 stop14h 04m
United Airlines
Deal found 3/25![United Airlines logo]()
$482
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:36 pm
MCI
- AGP
2 stops16h 19m
Lufthansa
Wed 9/99:35 am
AGP
- MCI
1 stop21h 22m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$527
This Cheapflightsfares deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:14 pm
MCI
- AGP
2 stops25h 51m
SWISS
Wed 8/266:30 am
AGP
- MCI
2 stops22h 10m
SWISS
Deal found 3/22![SWISS logo]()
$675
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:40 am
MCI
- MAD
2 stops17h 40m
Delta
Fri 10/22:35 pm
MAD
- MCI
2 stops16h 17m
Delta
Deal found 3/25![Delta logo]()
$751
This Flysmarter deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:40 pm
MCI
- AGP
2 stops17h 15m
Multiple Airlines
Tue 5/129:35 am
AGP
- MCI
1 stop19h 43m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$759
This KLM deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:03 pm
MCI
- MAD
1 stop14h 12m
KLM
Tue 4/286:00 am
MAD
- MCI
2 stops15h 30m
KLM
Deal found 3/24![KLM logo]()
$763
This Booking.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:21 pm
STL
- IBZ
2 stops37h 59m
British Airways
Wed 5/139:05 am
IBZ
- STL
2 stops17h 28m
British Airways
Deal found 3/22![British Airways logo]()
$808
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:35 pm
STL
- IBZ
1 stop33h 45m
American Airlines
Wed 5/139:05 am
IBZ
- STL
2 stops17h 28m
American Airlines
Deal found 3/22![American Airlines logo]()
$838
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:03 pm
STL
- LPA
2 stops18h 22m
Iberia
Tue 5/126:30 am
LPA
- STL
2 stops21h 49m
Iberia
Deal found 3/21![Iberia logo]()
$968
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:00 pm
MCI
- AGP
2 stops15h 55m
Lufthansa
Thu 4/306:45 pm
AGP
- MCI
2 stops35h 46m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$537
This Justfly.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:00 am
MCI
- TFS
2 stops31h 35m
Aer Lingus
Wed 5/68:25 pm
TFS
- MCI
2 stops27h 01m
Aer Lingus
Deal found 3/22![Aer Lingus logo]()
$1,088
This oojo deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:14 pm
MCI
- AGP
2 stops20h 21m
SWISS
Tue 8/254:50 pm
AGP
- MCI
2 stops35h 50m
SWISS
Deal found 3/25![SWISS logo]()
$698
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:32 pm
STL
- MAD
2 stops32h 18m
United Airlines
Sat 9/125:55 am
MAD
- STL
2 stops24h 05m
United Airlines
Deal found 3/21![United Airlines logo]()
$739
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:12 pm
MCI
- MAD
1 stop12h 03m
Delta
Tue 4/286:00 am
MAD
- MCI
2 stops18h 41m
Delta
Deal found 3/24![Delta logo]()
$763
This Booking.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:53 pm
STL
- IBZ
2 stops38h 32m
British Airways
Sat 5/27:45 pm
IBZ
- STL
2 stops30h 45m
British Airways
Deal found 3/25![British Airways logo]()
$843
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
MCI
- AGP
1 stop18h 35m
United Airlines
Tue 5/129:35 am
AGP
- MCI
1 stop19h 43m
United Airlines
Deal found 3/21![United Airlines logo]()
$788
This Finnair deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:06 pm
MCI
- MAD
1 stop12h 24m
Multiple Airlines
Wed 5/63:55 pm
MAD
- MCI
1 stop15h 11m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$886
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:05 am
MCI
- TFS
2 stops25h 15m
American Airlines
Tue 4/286:25 am
TFS
- MCI
2 stops22h 25m
American Airlines
Deal found 3/22![American Airlines logo]()
$922
This KLM deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:36 am
MCI
- BCN
1 stop16h 09m
KLM
Mon 4/2011:00 am
BCN
- MCI
1 stop16h 10m
KLM
Deal found 3/22![KLM logo]()
$959
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:15 am
MCI
- MAD
2 stops18h 50m
United Airlines
Sat 5/25:55 am
MAD
- MCI
2 stops20h 55m
United Airlines
Deal found 3/22![United Airlines logo]()
$807
This Booking.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:12 pm
STL
- IBZ
2 stops43h 48m
British Airways
Sat 5/167:45 pm
IBZ
- STL
2 stops27h 15m
British Airways
Deal found 3/25![British Airways logo]()
$891
This Finnair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:19 am
SGF
- MAD
1 stop20h 01m
Multiple Airlines
Thu 5/213:55 pm
MAD
- SGF
1 stop24h 04m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$910
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:52 pm
SGF
- MAD
2 stops17h 43m
Delta
Thu 5/219:50 am
MAD
- SGF
1 stop15h 14m
Delta
Deal found 3/21![Delta logo]()
$918
This Iberia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:21 pm
STL
- LPA
2 stops18h 44m
Iberia
Sat 5/26:30 am
LPA
- STL
2 stops19h 03m
Iberia
Deal found 3/24![Iberia logo]()
$1,026
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:10 am
SGF
- MAD
1 stop15h 20m
American Airlines
Thu 5/2111:45 am
MAD
- SGF
1 stop17h 55m
American Airlines
Deal found 3/23![American Airlines logo]()
$958
This KLM deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:42 pm
STL
- MAD
1 stop13h 33m
KLM
Sun 9/132:35 pm
MAD
- STL
2 stops16h 02m
KLM
Deal found 3/23![KLM logo]()
$979
This British Airways deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:27 pm
STL
- MAD
1 stop13h 38m
British Airways
Thu 5/710:30 am
MAD
- STL
2 stops16h 03m
British Airways
Deal found 3/25![British Airways logo]()
$895
This Justfly.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:05 pm
MCI
- SVQ
2 stops15h 25m
Lufthansa
Sat 5/212:20 pm
SVQ
- MCI
2 stops35h 04m
Lufthansa
Deal found 3/25![Lufthansa logo]()
$1,002
This Finnair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:33 am
MCI
- MAD
1 stop19h 47m
Multiple Airlines
Sun 4/2611:45 am
MAD
- MCI
1 stop19h 14m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$912
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:56 pm
MCI
- MAD
2 stops28h 54m
United Airlines
Tue 5/265:55 am
MAD
- MCI
2 stops24h 12m
United Airlines
Deal found 3/22![United Airlines logo]()
$840
Last-minute flights from Missouri to SpainDiscover last-minute flight deals from Missouri to Spain. Data last updated March 26, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Spain. Data last updated March 26, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 pm
MCI
- AGP
2 stops34h 40m
Multiple Airlines
Tue 4/286:30 am
AGP
- MCI
2 stops20h 15m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$532
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 pm
MCI
- AGP
2 stops34h 40m
Lufthansa
Fri 5/111:10 am
AGP
- MCI
2 stops19h 21m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$563
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 pm
MCI
- AGP
2 stops34h 40m
Lufthansa
Thu 4/305:45 pm
AGP
- MCI
2 stops36h 46m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$583
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:00 am
MCI
- AGP
2 stops33h 05m
SWISS
Wed 4/296:30 am
AGP
- MCI
2 stops22h 34m
SWISS
Deal found 3/22![SWISS logo]()
$515
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:00 am
MCI
- AGP
2 stops44h 20m
SWISS
Mon 4/276:30 am
AGP
- MCI
2 stops22h 29m
SWISS
Deal found 3/22![SWISS logo]()
$565
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/191:05 pm
MCI
- AGP
2 stops20h 40m
Lufthansa
Fri 5/111:10 am
AGP
- MCI
2 stops19h 21m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$641
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/191:05 pm
MCI
- AGP
2 stops16h 15m
Lufthansa
Thu 4/3012:30 pm
AGP
- MCI
2 stops42h 01m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$643
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:00 pm
MCI
- AGP
2 stops15h 55m
Lufthansa
Wed 4/296:45 pm
AGP
- MCI
2 stops35h 46m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$537
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:05 pm
MCI
- AGP
2 stops18h 00m
Lufthansa
Fri 5/111:10 am
AGP
- MCI
2 stops19h 21m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$557
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:45 pm
MCI
- AGP
2 stops17h 10m
Lufthansa
Thu 4/306:45 pm
AGP
- MCI
2 stops56h 05m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$544
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:40 pm
MCI
- AGP
2 stops22h 15m
Lufthansa
Fri 5/11:00 pm
AGP
- MCI
2 stops17h 31m
Lufthansa
Deal found 3/22![Lufthansa logo]()
$619
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:30 pm
STL
- MAD
1 stop13h 40m
Lufthansa
Wed 4/295:55 am
MAD
- STL
1 stop14h 30m
Lufthansa
Deal found 3/23![Lufthansa logo]()
$710
One-way flights from Missouri to SpainSearch for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
This oojo deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:18 pm
MCI
- MAD
2 stops17h 32m
British Airways
Deal found 3/23![British Airways logo]()
$316
This eDestinos deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:13 am
MCI
- MAD
1 stop16h 07m
Iberia
Deal found 3/23![Iberia logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:30 pm
STL
- BCN
2 stops26h 45m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$399
This Iberia deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:14 am
SGF
- MAD
1 stop15h 06m
Iberia
Deal found 3/22![Iberia logo]()
$406
This FlightHub deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:48 pm
SGF
- MAD
2 stops19h 47m
British Airways
Deal found 3/26![British Airways logo]()
$409
This Justfly.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:30 pm
STL
- BCN
2 stops23h 00m
Aer Lingus
Deal found 3/22![Aer Lingus logo]()
$409
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:15 am
SGF
- MAD
2 stops17h 35m
United Airlines
Deal found 3/22![United Airlines logo]()
$410
This Finnair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:14 am
SGF
- MAD
1 stop15h 06m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$411
This Justfly.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:21 pm
STL
- BCN
2 stops22h 09m
Aer Lingus
Deal found 3/25![Aer Lingus logo]()
$411
This Mytrip deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:36 pm
MCI
- MAD
2 stops53h 14m
Air Canada
Deal found 3/23![Air Canada logo]()
$411
This Cheapflightsfares deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/199:40 pm
STL
- BCN
1 stop17h 50m
British Airways
Deal found 3/21![British Airways logo]()
$420
This Justfly.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
MCI
- BCN
2 stops33h 30m
Aer Lingus
Deal found 3/23![Aer Lingus logo]()
$424
Find flight deals from Missouri to Spain
Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated March 26, 2026.
Round-trip from | $482 (United Airlines) |
|---|---|
One-way from | $316 (oojo) |
Popular in | June |
Cheapest in | January |
Average price | $1,020 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityMálaga
MCI - AGP
MCIAGP
Kansas City
Sun 8/16
6:23 am-7:35 am
2 stops18h 12m
Malaga
Wed 9/9
9:35 am-4:39 pm
1 stop14h 04m
$482
Kansas CityMálaga
MCI - AGP
MCIAGP
Kansas City
Sun 8/16
6:36 pm-5:55 pm
2 stops16h 19m
Malaga
Wed 9/9
9:35 am-11:57 pm
1 stop21h 22m
$527
Kansas CityMálaga
MCI - AGP
MCIAGP
Kansas City
Tue 4/21
7:00 pm-5:55 pm
2 stops15h 55m
Malaga
Thu 4/30
6:45 pm-11:31 pm
2 stops35h 46m
$537
Kansas CityMálaga
MCI - AGP
MCIAGP
Kansas City
Mon 8/17
3:14 pm-12:05 am
2 stops25h 51m
Malaga
Wed 8/26
6:30 am-9:40 pm
2 stops22h 10m
$675
Kansas CityMálaga
MCI - AGP
MCIAGP
Kansas City
Mon 8/17
3:14 pm-6:35 pm
2 stops20h 21m
Malaga
Tue 8/25
4:50 pm-9:40 pm
2 stops35h 50m
$698
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Sat 8/15
5:32 pm-8:50 am
2 stops32h 18m
Madrid Barajas
Sat 9/12
5:55 am-11:00 pm
2 stops24h 05m
$739
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 9/22
5:40 am-6:20 am
2 stops17h 40m
Madrid Barajas
Fri 10/2
2:35 pm-11:52 pm
2 stops16h 17m
$751
Kansas CityMálaga
MCI - AGP
MCIAGP
Kansas City
Mon 5/4
5:40 pm-5:55 pm
2 stops17h 15m
Malaga
Tue 5/12
9:35 am-10:18 pm
1 stop19h 43m
$759
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 4/21
3:03 pm-12:15 pm
1 stop14h 12m
Madrid Barajas
Tue 4/28
6:00 am-2:30 pm
2 stops15h 30m
$763
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 4/21
5:12 pm-12:15 pm
1 stop12h 03m
Madrid Barajas
Tue 4/28
6:00 am-5:41 pm
2 stops18h 41m
$763
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
MCI-MAD
STL-BCN
SGF-MAD
MCI-BCN
MCI-AGP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Spain
USMO-ES0
MCI-MAD
STL-BCN
SGF-MAD
MCI-BCN
What is the cheapest month to book a flight from Missouri to Spain?
Currently, February is the cheapest month in which you can book a flight from Missouri to Spain (average of $433). Flying from Missouri to Spain in June is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Top regions
Alternative routes for Missouri to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Spain by cabin class
Find flights from Missouri to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Spain flights
Browse other Missouri and Spain flight options. Last updated on March 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Spain
Find the right flight back to Missouri after your stay in Spain
Missouri to Spain flights
Consider these flights traveling from Missouri to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 10 airlines flying from Missouri to Spain
Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$433 | Average$747 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$437 | Average$719 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$457 | Average$753 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$461 | Average$790 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$480 | Average$1,167 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$485 | Average$912 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$487 | Average$820 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$488 | Average$953 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$490 | Average$877 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$560 | Average$1,008 | FlexibilityNo cancel fee | On-time67% |