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$241+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:45 pm
STL
-
BCN
1 stop11h 25m
United Airlines
Wed 11/251:35 pm
BCN
-
STL
2 stops31h 43m
United Airlines
Deal found 1/21$415
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:37 pm
MCI
-
BCN
1 stop12h 43m
United Airlines
Tue 3/1012:35 pm
BCN
-
MCI
2 stops39h 24m
United Airlines
Deal found 1/20$415
This Cheapflightsfares deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1811:46 am
STL
-
BCN
1 stop14h 04m
Finnair
Wed 2/253:05 pm
BCN
-
STL
1 stop15h 51m
Finnair
Deal found 1/19$419
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:15 am
MCI
-
BCN
2 stops19h 05m
United Airlines
Fri 4/2412:15 pm
BCN
-
MCI
2 stops29h 12m
United Airlines
Deal found 1/21$419
This oojo deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:54 pm
STL
-
VLC
2 stops17h 41m
British Airways
Tue 4/288:30 pm
VLC
-
STL
1 stop30h 00m
British Airways
Deal found 1/20$420
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:30 pm
MCI
-
MAD
2 stops30h 30m
United Airlines
Tue 2/171:35 pm
MAD
-
MCI
2 stops39h 24m
United Airlines
Deal found 1/21$422
This oojo deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/182:00 pm
STL
-
BCN
2 stops14h 10m
British Airways
Wed 2/2510:40 am
BCN
-
STL
1 stop19h 42m
British Airways
Deal found 1/19$422
This oojo deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:16 pm
MCI
-
BCN
2 stops16h 49m
British Airways
Tue 2/2412:30 pm
BCN
-
MCI
1 stop17h 38m
British Airways
Deal found 1/18$422
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1010:00 am
STL
-
MAD
2 stops15h 00m
United Airlines
Tue 3/1712:40 pm
MAD
-
STL
2 stops38h 27m
United Airlines
Deal found 1/20$422
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:15 am
MCI
-
MAD
2 stops18h 50m
United Airlines
Fri 4/2412:45 pm
MAD
-
MCI
2 stops28h 42m
United Airlines
Deal found 1/20$424
This oojo deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:38 pm
MCI
-
AGP
2 stops22h 27m
British Airways
Tue 3/175:50 pm
AGP
-
MCI
2 stops36h 22m
British Airways
Deal found 1/20$424
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 am
STL
-
MAD
2 stops20h 15m
United Airlines
Wed 3/1112:40 pm
MAD
-
STL
2 stops32h 02m
United Airlines
Deal found 1/20$424

Find flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated January 21, 2026.

Round-trip from

$415
(United Airlines)

One-way from

$241
(oojo)

Popular in

June

Cheapest in

January

Average price

$505
From Missouri to Spain
Search Deals
One-way flight from Missouri to Spain
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($301 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Tue 3/3

12:37 pm-8:20 am

1 stop12h 43m

Barcelona-El Prat

Tue 3/10

12:35 pm-9:59 pm

2 stops39h 24m

$415

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Wed 4/15

3:21 pm-1:15 pm

1 stop14h 54m

Barcelona-El Prat

Fri 4/24

12:15 pm-10:27 am

2 stops29h 12m

$415

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 3/24

10:00 am-9:00 am

2 stops17h 00m

Barcelona-El Prat

Thu 4/9

12:15 pm-10:56 pm

2 stops41h 41m

$419

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Tue 3/24

9:15 am-9:00 am

2 stops17h 45m

Barcelona-El Prat

Fri 4/10

12:15 pm-4:42 pm

2 stops35h 27m

$419

St. LouisValencia

STL - VLC

STLVLC

Lambert-St Louis

Sun 4/19

6:54 pm-7:35 pm

2 stops17h 41m

Valencia

Tue 4/28

8:30 pm-7:30 pm

1 stop30h 00m

$420

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Tue 2/17

4:16 pm-4:05 pm

2 stops16h 49m

Barcelona-El Prat

Tue 2/24

12:30 pm-11:08 pm

1 stop17h 38m

$422

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Sun 2/8

6:30 pm-8:00 am

2 stops30h 30m

Madrid Barajas

Tue 2/17

1:35 pm-9:59 pm

2 stops39h 24m

$422

Kansas CityMálaga

MCI - AGP

MCIAGP

Kansas City

Tue 3/3

12:38 pm-6:05 pm

2 stops22h 27m

Malaga

Tue 3/17

5:50 pm-12:12 am

2 stops36h 22m

$424

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 4/14

11:44 am-1:15 pm

2 stops18h 31m

Barcelona-El Prat

Tue 4/28

7:40 am-7:30 pm

1 stop18h 50m

$429

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Mon 2/23

9:13 am-6:30 pm

2 stops26h 17m

Madrid Barajas

Mon 3/2

8:50 pm-10:44 pm

2 stops32h 54m

$431

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $438). Flying from Missouri to Spain in June is currently the most expensive (average of $764). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Spain?

    United Airlines, British Airways, and Iberia can get you from Missouri to Spain in just under 12h 43m. Your travel time can differ by up to 4h 58m. There are 4803 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $322. However, be on the lookout for offers from United Airlines and Iberia, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $438). Flying from Missouri to Spain in June is currently the most expensive (average of $764). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Missouri to Spain

Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$433Average$746FlexibilityNo cancel feeOn-time75%
Virgin AtlanticCheapest$437Average$756FlexibilityNo cancel feeOn-time72%
Air FranceCheapest$457Average$753FlexibilityNo cancel feeOn-time77%
LufthansaCheapest$482Average$1,121FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$483Average$856FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$485Average$1,059FlexibilityNo cancel feeOn-time71%
DeltaCheapest$487Average$867FlexibilityNo cancel feeOn-timeN/A
IberiaCheapest$488Average$1,005FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$490Average$877FlexibilityNo cancel feeOn-time69%
Air CanadaCheapest$624Average$1,077FlexibilityNo cancel feeOn-time67%

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