$307+ Cheap flights from Missouri to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Sep 30 — Oct 71
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Spain with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Spain
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 31, 2026.
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 31, 2026.
This eDestinos deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:41 pm -
2 stops30h 39m
Tue 1/121:55 pm -
1 stop14h 10m
Deal found 8/30![Virgin Atlantic logo]()
$673
This Gotogate deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:40 pm -
1 stop11h 10m
Wed 10/141:30 pm -
1 stop13h 50m
Deal found 8/29![Multiple Airlines logo]()
$679
This Trip.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:10 pm -
1 stop12h 50m
Wed 10/141:15 pm -
1 stop31h 45m
Deal found 8/29![Air Canada logo]()
$682
This Cheapflightsfares deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:22 am -
2 stops24h 18m
Tue 10/2010:05 am -
2 stops18h 55m
Deal found 8/28![SWISS logo]()
$691
This Trip.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:10 pm -
1 stop12h 50m
Fri 10/161:15 pm -
1 stop31h 45m
Deal found 8/30![Multiple Airlines logo]()
$694
This Gotogate deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:10 pm -
1 stop12h 50m
Wed 10/1412:15 pm -
1 stop13h 26m
Deal found 8/30![Multiple Airlines logo]()
$698
This Expedia deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:00 pm -
2 stops19h 45m
Tue 12/812:00 pm -
1 stop15h 59m
Deal found 8/30![Iberia logo]()
$701
This Gotogate deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:10 pm -
1 stop12h 50m
Wed 10/146:40 am -
2 stops19h 01m
Deal found 8/28![Multiple Airlines logo]()
$702
This Expedia deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:03 am -
1 stop20h 07m
Tue 12/812:00 pm -
1 stop15h 59m
Deal found 8/30![British Airways logo]()
$704
This Gotogate deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:40 pm -
1 stop11h 10m
Wed 10/145:55 am -
2 stops19h 46m
Deal found 8/28![Air Canada logo]()
$704
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:35 am -
1 stop18h 40m
Wed 10/1412:15 pm -
2 stops34h 28m
Deal found 8/30![United Airlines logo]()
$706
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:05 pm -
1 stop15h 10m
Wed 10/2812:35 pm -
2 stops39h 20m
Deal found 8/30![United Airlines logo]()
$706
Best flights from Missouri to SpainDiscover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 31, 2026.
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 31, 2026.
This FlightHub deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:10 pm -
1 stop12h 50m
Wed 10/141:15 pm -
1 stop31h 45m
Deal found 8/30![Multiple Airlines logo]()
$698
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:35 am -
1 stop18h 40m
Wed 10/1412:15 pm -
2 stops34h 28m
Deal found 8/30![United Airlines logo]()
$706
This Cheapflightsfares deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:14 pm -
2 stops25h 51m
Wed 10/216:30 am -
2 stops22h 30m
Deal found 8/30![SWISS logo]()
$709
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:08 am -
1 stop17h 32m
Tue 12/810:35 am -
1 stop15h 37m
Deal found 8/29![Delta logo]()
$726
This KLM deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:45 pm -
2 stops15h 40m
Wed 10/710:25 am -
2 stops17h 24m
Deal found 8/28![KLM logo]()
$732
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/182:49 pm -
2 stops20h 56m
Fri 2/127:00 am -
2 stops21h 36m
Deal found 8/26![American Airlines logo]()
$743
This Cheapflightsfares deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:29 pm -
2 stops14h 36m
Fri 10/237:15 am -
2 stops21h 06m
Deal found 8/30![Lufthansa logo]()
$797
This FlightHub deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/168:07 pm -
2 stops41h 13m
Sun 2/287:25 pm -
2 stops35h 53m
Deal found 8/30![British Airways logo]()
$835
This Air Canada deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1310:00 am -
3 stops19h 00m
Wed 2/2412:50 pm -
3 stops30h 37m
Deal found 8/27![Air Canada logo]()
$992
This Travelocity deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:35 pm -
2 stops54h 05m
Tue 10/66:30 am -
2 stops19h 20m
Deal found 8/26![Iberia logo]()
$1,110
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2711:50 am -
1 stop13h 30m
Tue 10/1311:15 am -
1 stop15h 31m
Deal found 8/27![United Airlines logo]()
$717
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/132:17 pm -
2 stops18h 03m
Fri 12/186:05 am -
2 stops18h 15m
Deal found 8/27![Delta logo]()
$742
This FlightHub deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:50 pm -
2 stops40h 20m
Tue 11/101:10 pm -
2 stops39h 41m
Deal found 8/28![Multiple Airlines logo]()
$766
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:09 pm -
1 stop17h 06m
Tue 11/173:10 pm -
1 stop13h 41m
Deal found 8/29![United Airlines logo]()
$726
This FlightHub deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:50 pm -
2 stops16h 55m
Mon 11/165:50 pm -
2 stops35h 02m
Deal found 8/28![Lufthansa logo]()
$814
This Finnair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:59 pm -
1 stop14h 31m
Sun 10/43:55 pm -
1 stop14h 29m
Deal found 8/30![Multiple Airlines logo]()
$781
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:10 pm -
2 stops18h 25m
Tue 10/132:35 pm -
1 stop25h 10m
Deal found 8/26![Delta logo]()
$791
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:50 am -
1 stop13h 30m
Wed 10/2111:15 am -
1 stop15h 31m
Deal found 8/30![United Airlines logo]()
$726
This Cheapflightsfares deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:30 pm -
1 stop19h 05m
Wed 11/412:50 pm -
2 stops17h 34m
Deal found 8/27![Lufthansa logo]()
$848
This FlightHub deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:44 am -
2 stops27h 21m
Tue 10/61:30 pm -
2 stops40h 53m
Deal found 8/28![British Airways logo]()
$944
This Finnair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:09 am -
1 stop16h 11m
Tue 10/2011:30 am -
1 stop18h 29m
Deal found 8/30![Multiple Airlines logo]()
$781
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:38 pm -
2 stops14h 32m
Mon 10/261:05 pm -
2 stops16h 49m
Deal found 8/26![Delta logo]()
$792
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:46 pm -
1 stop31h 19m
Tue 10/201:30 pm -
2 stops41h 14m
Deal found 8/28![United Airlines logo]()
$727
This Justfly.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:45 pm -
2 stops15h 45m
Tue 11/247:35 pm -
2 stops33h 16m
Deal found 8/31![Multiple Airlines logo]()
$791
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:30 am -
2 stops17h 00m
Tue 10/132:35 pm -
1 stop25h 10m
Deal found 8/26![Delta logo]()
$795
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
2 stops20h 00m
Tue 12/86:50 am -
2 stops22h 02m
Deal found 8/28![United Airlines logo]()
$730
This Cheapflightsfares deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:20 pm -
2 stops22h 10m
Fri 10/236:05 am -
1 stop14h 20m
Deal found 8/27![Lufthansa logo]()
$889
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/172:30 pm -
2 stops19h 50m
Sat 1/234:10 pm -
2 stops32h 05m
Deal found 8/29![Delta logo]()
$797
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/246:00 am -
1 stop20h 15m
Wed 3/31:25 pm -
2 stops28h 03m
Deal found 8/26![United Airlines logo]()
$731
This Air Canada deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1711:25 am -
3 stops19h 45m
Sat 1/236:00 am -
3 stops22h 45m
Deal found 8/29![Air Canada logo]()
$1,199
Last-minute flights from Missouri to SpainDiscover last-minute flight deals from Missouri to Spain. Data last updated August 31, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Spain. Data last updated August 31, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:46 pm -
1 stop31h 34m
Tue 10/1312:00 pm -
1 stop18h 44m
Deal found 8/30![United Airlines logo]()
$711
This Booking.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:00 am -
2 stops19h 00m
Tue 10/1312:15 pm -
2 stops33h 03m
Deal found 8/30![Air Canada logo]()
$718
This Booking.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:00 am -
1 stop16h 35m
Tue 10/133:20 pm -
1 stop26h 56m
Deal found 8/29![British Airways logo]()
$719
This Gotogate deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:40 pm -
1 stop11h 10m
Wed 10/141:30 pm -
1 stop13h 50m
Deal found 8/29![Multiple Airlines logo]()
$679
This Trip.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:10 pm -
1 stop12h 50m
Wed 10/141:15 pm -
1 stop31h 45m
Deal found 8/29![Air Canada logo]()
$682
This Gotogate deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:10 pm -
1 stop12h 50m
Wed 10/1412:15 pm -
1 stop13h 26m
Deal found 8/30![Multiple Airlines logo]()
$698
This Gotogate deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:40 pm -
1 stop11h 10m
Wed 10/145:55 am -
2 stops19h 46m
Deal found 8/28![Air Canada logo]()
$704
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:05 pm -
1 stop15h 10m
Wed 10/2812:35 pm -
2 stops39h 20m
Deal found 8/30![United Airlines logo]()
$706
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:35 am -
1 stop18h 40m
Wed 10/1412:15 pm -
2 stops34h 28m
Deal found 8/30![United Airlines logo]()
$706
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:30 am -
1 stop16h 35m
Wed 10/145:55 am -
1 stop14h 30m
Deal found 8/28![United Airlines logo]()
$716
This Air Canada deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:40 pm -
1 stop11h 10m
Fri 10/91:30 pm -
1 stop31h 30m
Deal found 8/28![Air Canada logo]()
$717
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:05 am -
2 stops15h 30m
Wed 10/1411:10 am -
2 stops16h 41m
Deal found 8/30![Delta logo]()
$718
One-way flights from Missouri to SpainSearch for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated August 31, 2026.
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated August 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:30 pm -
2 stops57h 55m
Deal found 8/27![Multiple Airlines logo]()
$307
This Expedia deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/612:23 pm -
2 stops23h 07m
Deal found 8/29![Iberia logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:30 pm -
2 stops58h 00m
Deal found 8/27![Multiple Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:44 pm -
3 stops35h 46m
Deal found 8/26![Multiple Airlines logo]()
$342
This Expedia deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:12 am -
1 stop16h 38m
Deal found 8/29![Iberia logo]()
$343
This Booking.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2710:16 am -
1 stop16h 04m
Deal found 8/27![British Airways logo]()
$345
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/224:13 pm -
2 stops17h 57m
Deal found 8/27![American Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2710:16 am -
2 stops15h 34m
Deal found 8/27![American Airlines logo]()
$350
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:36 am -
2 stops18h 39m
Deal found 8/26![United Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:32 pm -
3 stops54h 43m
Deal found 8/28![Multiple Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:00 am -
3 stops22h 45m
Deal found 8/29![United Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2711:30 am -
3 stops21h 50m
Deal found 8/27![United Airlines logo]()
$374
Find flight deals from Missouri to Spain
Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated August 31, 2026.
Round-trip from | $673 (eDestinos) |
|---|---|
One-way from | $307 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $1,123 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 31, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisBarcelona
STL Lambert-St Louis - BCN Barcelona-El Prat
STLBCN
Lambert-St Louis
Mon 9/28
12:10 pm-8:00 am
1 stop12h 50m
Barcelona-El Prat
Wed 10/14
1:15 pm-2:00 pm
1 stop31h 45m
$698
St. LouisBarcelona
STL Lambert-St Louis - BCN Barcelona-El Prat
STLBCN
Lambert-St Louis
Mon 9/28
11:35 am-1:15 pm
1 stop18h 40m
Barcelona-El Prat
Wed 10/14
12:15 pm-3:43 pm
2 stops34h 28m
$706
Kansas CityMálaga
MCI Kansas City - AGP Malaga
MCIAGP
Kansas City
Tue 10/6
3:14 pm-12:05 am
2 stops25h 51m
Malaga
Wed 10/21
6:30 am-10:00 pm
2 stops22h 30m
$709
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Sun 9/27
11:50 am-8:20 am
1 stop13h 30m
Barcelona-El Prat
Tue 10/13
11:15 am-7:46 pm
1 stop15h 31m
$717
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Tue 12/1
8:08 am-8:40 am
1 stop17h 32m
Barcelona-El Prat
Tue 12/8
10:35 am-7:12 pm
1 stop15h 37m
$726
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Tue 11/10
1:09 pm-1:15 pm
1 stop17h 06m
Barcelona-El Prat
Tue 11/17
3:10 pm-9:51 pm
1 stop13h 41m
$726
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Wed 10/14
11:50 am-8:20 am
1 stop13h 30m
Barcelona-El Prat
Wed 10/21
11:15 am-7:46 pm
1 stop15h 31m
$726
Kansas CityMadrid
MCI Kansas City - MAD Madrid Barajas
MCIMAD
Kansas City
Tue 10/6
5:46 pm-8:05 am
1 stop31h 19m
Madrid Barajas
Tue 10/20
1:30 pm-11:44 pm
2 stops41h 14m
$727
Kansas CityBarcelona
MCI Kansas City - BCN Barcelona-El Prat
MCIBCN
Kansas City
Tue 12/1
6:00 am-9:00 am
2 stops20h 00m
Barcelona-El Prat
Tue 12/8
6:50 am-9:52 pm
2 stops22h 02m
$730
Kansas CityMadrid
MCI Kansas City - MAD Madrid Barajas
MCIMAD
Kansas City
Wed 2/24
6:00 am-9:15 am
1 stop20h 15m
Madrid Barajas
Wed 3/3
1:25 pm-10:28 am
2 stops28h 03m
$731
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
STL-VLC
MCI-MAD
MCI-BCN
MCI-VLC
STL-BCN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Spain
USMO-ES0
STL-VLC
MCI-MAD
MCI-BCN
MCI-VLC
What is the cheapest month to book a flight from Missouri to Spain?
Currently, February is the cheapest month in which you can book a flight from Missouri to Spain (average of $597). Flying from Missouri to Spain in June is currently the most expensive (average of $1,485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Missouri to Spain?
Booking 8 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Top regions
Alternative routes for Missouri to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Spain by cabin class
Find flights from Missouri to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Spain flights
Browse other Missouri and Spain flight options. Last updated on August 31, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Spain
Find the right flight back to Missouri after your stay in Spain
Missouri to Spain flights
Consider these flights traveling from Missouri to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 10 airlines flying from Missouri to Spain
Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$382 | Average$656 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$433 | Average$905 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$461 | Average$910 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$480 | Average$1,214 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$485 | Average$915 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$488 | Average$838 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$490 | Average$997 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$508 | Average$940 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$624 | Average$1,133 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$1,051 | Average$1,188 | FlexibilityNo cancel fee | On-time77% |