$271+ Cheap flights from Missouri to Spain
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — MAD
Aug 1 — Aug 81
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2026.
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2026.
This Gotogate deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:10 pm
STL
- MAD
1 stop11h 40m
Multiple Airlines
Tue 10/205:55 am
MAD
- STL
1 stop14h 30m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$700
This Trip.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:10 pm
STL
- MAD
1 stop11h 40m
Multiple Airlines
Thu 10/81:30 pm
MAD
- STL
1 stop31h 30m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$703
This Gotogate deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:10 pm
STL
- MAD
1 stop11h 40m
Air Canada
Thu 10/86:20 am
MAD
- STL
2 stops20h 40m
Air Canada
Deal found 6/28![Air Canada logo]()
$708
This Gotogate deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:55 am
STL
- MAD
1 stop16h 55m
Multiple Airlines
Fri 10/96:00 am
MAD
- STL
1 stop14h 25m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$709
This Air Canada deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1112:10 pm
STL
- MAD
1 stop11h 40m
Air Canada
Wed 10/2112:45 pm
MAD
- STL
2 stops32h 32m
Air Canada
Deal found 6/28![Air Canada logo]()
$714
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:30 am
STL
- MAD
1 stop18h 30m
United Airlines
Wed 10/2112:45 pm
MAD
- STL
2 stops33h 58m
United Airlines
Deal found 6/30![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:15 am
COU
- MAD
2 stops37h 45m
United Airlines
Thu 12/101:25 pm
MAD
- COU
2 stops40h 33m
United Airlines
Deal found 6/29![United Airlines logo]()
$718
This Air Canada deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1112:10 pm
STL
- MAD
1 stop11h 40m
Air Canada
Tue 10/201:30 pm
MAD
- STL
2 stops38h 51m
Air Canada
Deal found 6/28![Air Canada logo]()
$718
This United deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:00 am
STL
- MAD
2 stops18h 00m
Multiple Airlines
Tue 10/2712:25 pm
MAD
- STL
2 stops32h 05m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$719
This oojo deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:30 pm
STL
- MAD
1 stop13h 50m
Lufthansa
Fri 10/96:00 am
MAD
- STL
1 stop14h 25m
Lufthansa
Deal found 6/28![Lufthansa logo]()
$720
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:50 pm
STL
- MAD
1 stop33h 10m
United Airlines
Tue 10/201:30 pm
MAD
- STL
1 stop31h 30m
United Airlines
Deal found 6/28![United Airlines logo]()
$721
This Air Canada deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:04 am
STL
- MAD
2 stops17h 31m
Air Canada
Wed 10/2112:45 pm
MAD
- STL
2 stops32h 32m
Air Canada
Deal found 6/28![Air Canada logo]()
$723
Best flights from Missouri to SpainDiscover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2026.
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2026.
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:24 pm
STL
- MAD
1 stop11h 21m
United Airlines
Wed 2/171:25 pm
MAD
- STL
2 stops34h 15m
United Airlines
Deal found 7/1![United Airlines logo]()
$715
This British Airways deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:35 pm
STL
- MAD
1 stop15h 30m
British Airways
Tue 10/2712:00 pm
MAD
- STL
1 stop17h 58m
British Airways
Deal found 6/29![British Airways logo]()
$727
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am
STL
- MAD
2 stops20h 55m
Delta
Fri 10/3010:00 am
MAD
- STL
2 stops19h 26m
Delta
Deal found 6/29![Delta logo]()
$740
This Finnair deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:57 am
MCI
- MAD
1 stop14h 08m
Multiple Airlines
Tue 10/203:55 pm
MAD
- MCI
1 stop14h 28m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$759
This FlightHub deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:29 pm
STL
- VLC
2 stops14h 31m
Lufthansa
Wed 11/41:00 pm
VLC
- STL
2 stops39h 13m
Lufthansa
Deal found 7/1![Lufthansa logo]()
$787
This Cheapflightsfares deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:32 am
MCI
- BCN
2 stops33h 03m
SWISS
Wed 9/306:00 am
BCN
- MCI
2 stops23h 04m
SWISS
Deal found 7/2![SWISS logo]()
$812
This Finnair deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:03 pm
MCI
- BCN
1 stop14h 07m
Finnair
Wed 9/3010:30 am
BCN
- MCI
1 stop20h 53m
Finnair
Deal found 7/2![Finnair logo]()
$843
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:07 pm
STL
- IBZ
2 stops15h 33m
American Airlines
Tue 8/255:45 pm
IBZ
- STL
1 stop32h 45m
American Airlines
Deal found 7/2![American Airlines logo]()
$904
This Iberia deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:31 am
STL
- IBZ
2 stops18h 24m
Iberia
Thu 11/125:45 pm
IBZ
- STL
2 stops34h 10m
Iberia
Deal found 6/30![Iberia logo]()
$1,008
This KLM deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:20 pm
MCI
- IBZ
2 stops18h 45m
KLM
Sat 9/2610:35 pm
IBZ
- MCI
2 stops25h 57m
KLM
Deal found 6/28![KLM logo]()
$1,208
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:15 am
COU
- MAD
2 stops37h 45m
United Airlines
Thu 12/101:25 pm
MAD
- COU
2 stops40h 33m
United Airlines
Deal found 6/27![United Airlines logo]()
$718
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am
STL
- MAD
1 stop20h 55m
Delta
Fri 12/1810:00 am
MAD
- STL
2 stops20h 18m
Delta
Deal found 6/28![Delta logo]()
$740
This KAYAK deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:05 pm
STL
- VLC
2 stops19h 50m
Multiple Airlines
Fri 12/186:10 am
VLC
- STL
1 stop14h 35m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$790
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:27 am
STL
- MAD
2 stops14h 38m
United Airlines
Thu 10/2211:15 am
MAD
- STL
2 stops18h 44m
United Airlines
Deal found 6/27![United Airlines logo]()
$740
This British Airways deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:40 pm
STL
- IBZ
1 stop12h 55m
British Airways
Tue 8/259:05 am
IBZ
- STL
2 stops22h 09m
British Airways
Deal found 6/30![British Airways logo]()
$842
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:55 pm
STL
- VLC
2 stops19h 55m
Delta
Wed 10/76:35 am
VLC
- STL
2 stops21h 41m
Delta
Deal found 6/29![Delta logo]()
$794
This British Airways deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/193:31 pm
COU
- MAD
1 stop33h 49m
Multiple Airlines
Fri 12/1810:35 am
MAD
- COU
2 stops18h 57m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$809
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:46 pm
MCI
- MAD
1 stop31h 19m
United Airlines
Tue 10/131:30 pm
MAD
- MCI
2 stops41h 29m
United Airlines
Deal found 7/1![United Airlines logo]()
$755
This British Airways deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:21 am
STL
- MAD
1 stop15h 14m
British Airways
Mon 11/21:00 pm
MAD
- STL
1 stop16h 29m
British Airways
Deal found 6/29![British Airways logo]()
$886
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:58 pm
MCI
- AGP
2 stops18h 17m
Delta
Wed 8/191:25 pm
AGP
- MCI
2 stops33h 48m
Delta
Deal found 6/28![Delta logo]()
$809
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:39 pm
MCI
- MAD
2 stops29h 11m
United Airlines
Fri 10/2311:15 am
MAD
- MCI
1 stop15h 31m
United Airlines
Deal found 7/1![United Airlines logo]()
$762
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:30 am
MCI
- MAD
1 stop13h 50m
Delta
Tue 10/206:00 am
MAD
- MCI
2 stops20h 05m
Delta
Deal found 6/30![Delta logo]()
$810
This Finnair deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:51 pm
COU
- MAD
1 stop14h 34m
Multiple Airlines
Fri 12/1812:00 pm
MAD
- COU
1 stop15h 55m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$893
This Gurufare deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:07 am
MCI
- AGP
1 stop18h 28m
Lufthansa
Wed 8/199:35 am
AGP
- MCI
1 stop21h 24m
Lufthansa
Deal found 6/28![Lufthansa logo]()
$1,121
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:08 pm
STL
- VLC
2 stops16h 02m
United Airlines
Thu 11/51:00 pm
VLC
- STL
1 stop31h 45m
United Airlines
Deal found 7/1![United Airlines logo]()
$767
This British Airways deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:13 pm
STL
- IBZ
2 stops35h 42m
British Airways
Thu 11/129:05 am
IBZ
- STL
2 stops19h 03m
British Airways
Deal found 7/1![British Airways logo]()
$975
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:30 am
MCI
- MAD
1 stop13h 50m
Delta
Mon 10/196:00 am
MAD
- MCI
2 stops20h 05m
Delta
Deal found 6/28![Delta logo]()
$810
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:32 am
COU
- MAD
1 stop19h 58m
American Airlines
Wed 7/291:35 pm
MAD
- COU
1 stop14h 26m
American Airlines
Deal found 6/27![American Airlines logo]()
$1,229
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:08 pm
STL
- VLC
2 stops27h 12m
United Airlines
Thu 11/56:20 pm
VLC
- STL
1 stop26h 25m
United Airlines
Deal found 6/28![United Airlines logo]()
$767
This United deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:30 pm
STL
- IBZ
1 stop13h 20m
Multiple Airlines
Tue 8/2512:35 pm
IBZ
- STL
1 stop31h 50m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$970
Last-minute flights from Missouri to SpainDiscover last-minute flight deals from Missouri to Spain. Data last updated July 2, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Spain. Data last updated July 2, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:45 pm
MCI
- AGP
2 stops30h 50m
United Airlines
Tue 8/49:35 am
AGP
- MCI
1 stop21h 24m
United Airlines
Deal found 6/28![United Airlines logo]()
$850
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:40 pm
MCI
- AGP
2 stops18h 00m
Delta
Tue 8/45:55 am
AGP
- MCI
2 stops33h 46m
Delta
Deal found 6/28![Delta logo]()
$865
This Flighttix deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:10 pm
STL
- BCN
1 stop12h 50m
Multiple Airlines
Wed 8/53:15 pm
BCN
- STL
1 stop13h 11m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$868
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:58 pm
MCI
- AGP
2 stops18h 17m
Delta
Wed 8/191:25 pm
AGP
- MCI
2 stops33h 48m
Delta
Deal found 6/28![Delta logo]()
$809
This Ovago deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:07 am
MCI
- AGP
1 stop18h 28m
Multiple Airlines
Wed 8/196:30 am
AGP
- MCI
2 stops18h 00m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$856
This Booking.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:10 pm
STL
- BCN
1 stop12h 50m
Multiple Airlines
Wed 8/191:15 pm
BCN
- STL
1 stop31h 47m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$862
This Gotogate deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:10 pm
STL
- BCN
1 stop12h 50m
Air Canada
Wed 8/1912:15 pm
BCN
- STL
2 stops33h 42m
Air Canada
Deal found 6/27![Air Canada logo]()
$867
This Expedia deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:07 pm
STL
- IBZ
2 stops14h 28m
British Airways
Tue 8/259:05 am
IBZ
- STL
2 stops21h 37m
British Airways
Deal found 6/27![British Airways logo]()
$839
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:42 pm
STL
- IBZ
2 stops15h 43m
American Airlines
Tue 8/259:05 am
IBZ
- STL
2 stops17h 22m
American Airlines
Deal found 6/30![American Airlines logo]()
$845
This Expedia deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:54 pm
STL
- IBZ
2 stops16h 56m
British Airways
Tue 8/259:05 am
IBZ
- STL
2 stops21h 37m
British Airways
Deal found 7/2![British Airways logo]()
$837
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:40 pm
STL
- BCN
2 stops23h 35m
Multiple Airlines
Wed 8/265:50 am
BCN
- STL
2 stops15h 12m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$847
This Air Canada deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:10 pm
STL
- MAD
1 stop11h 40m
Air Canada
Thu 10/2912:25 pm
MAD
- STL
2 stops32h 05m
Air Canada
Deal found 6/28![Air Canada logo]()
$866
One-way flights from Missouri to SpainSearch for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated July 2, 2026.
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated July 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:34 pm
STL
- BCN
2 stops44h 31m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:07 pm
MCI
- BCN
3 stops58h 13m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:07 pm
MCI
- BCN
3 stops57h 33m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:34 pm
STL
- MAD
3 stops41h 51m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:07 pm
MCI
- BCN
3 stops57h 03m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:35 am
STL
- BCN
3 stops48h 50m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:35 am
STL
- BCN
3 stops24h 20m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:34 pm
STL
- MAD
3 stops41h 51m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$328
This oojo deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:00 am
STL
- MAD
1 stop19h 20m
British Airways
Deal found 6/30![British Airways logo]()
$334
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:50 pm
STL
- MAD
2 stops15h 00m
British Airways
Deal found 6/30![British Airways logo]()
$338
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am
STL
- MAD
2 stops18h 45m
United Airlines
Deal found 7/1![United Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:07 pm
MCI
- BCN
3 stops39h 43m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$343
Find flight deals from Missouri to Spain
Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated July 2, 2026.
Round-trip from | $700 (Gotogate) |
|---|---|
One-way from | $271 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $1,097 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Tue 11/17
1:24 pm-7:45 am
1 stop11h 21m
Madrid Barajas
Wed 2/17
1:25 pm-4:40 pm
2 stops34h 15m
$715
ColumbiaMadrid
COU - MAD
COUMAD
Columbia Regional
Sun 12/6
11:15 am-8:00 am
2 stops37h 45m
Madrid Barajas
Thu 12/10
1:25 pm-10:58 pm
2 stops40h 33m
$718
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Wed 10/14
9:35 pm-8:05 pm
1 stop15h 30m
Madrid Barajas
Tue 10/27
12:00 pm-11:58 pm
1 stop17h 58m
$727
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Wed 10/21
6:00 am-9:55 am
2 stops20h 55m
Madrid Barajas
Fri 10/30
10:00 am-11:26 pm
2 stops19h 26m
$740
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Sun 12/13
6:00 am-9:55 am
1 stop20h 55m
Madrid Barajas
Fri 12/18
10:00 am-11:18 pm
2 stops20h 18m
$740
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Mon 10/19
10:27 am-8:05 am
2 stops14h 38m
Madrid Barajas
Thu 10/22
11:15 am-10:59 pm
2 stops18h 44m
$740
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 9/29
5:46 pm-8:05 am
1 stop31h 19m
Madrid Barajas
Tue 10/13
1:30 pm-11:59 pm
2 stops41h 29m
$755
Quickest round-trip
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 10/6
11:57 am-9:05 am
1 stop14h 08m
Madrid Barajas
Tue 10/20
3:55 pm-11:23 pm
1 stop14h 28m
$759
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Sat 10/17
6:39 pm-6:50 am
2 stops29h 11m
Madrid Barajas
Fri 10/23
11:15 am-7:46 pm
1 stop15h 31m
$762
St. LouisValencia
STL - VLC
STLVLC
Lambert-St Louis
Mon 11/2
1:08 pm-12:10 pm
2 stops16h 02m
Valencia
Thu 11/5
1:00 pm-1:45 pm
1 stop31h 45m
$767
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Spain
Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
MCI-AGP
STL-IBZ
STL-BCN
STL-MAD
MCI-MAD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Spain
USMO-ES0
MCI-AGP
STL-IBZ
STL-BCN
STL-MAD
What is the cheapest month to book a flight from Missouri to Spain?
Currently, March is the cheapest month in which you can book a flight from Missouri to Spain (average of $405). Flying from Missouri to Spain in June is currently the most expensive (average of $927). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Missouri to Spain?
Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Spain. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Spain
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spain by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Spain by cabin class
Find flights from Missouri to Spain, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Spain flights
Browse other Missouri and Spain flight options. Last updated on July 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Spain
Find the right flight back to Missouri after your stay in Spain
Missouri to Spain flights
Consider these flights traveling from Missouri to Spain.
Fly to Spain regions
Consider these flights traveling to Spain regions.
Top 9 airlines flying from Missouri to Spain
Discover the top 9 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$433 | Average$677 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$452 | Average$823 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$461 | Average$876 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$480 | Average$1,145 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$485 | Average$891 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$490 | Average$960 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$508 | Average$812 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$560 | Average$1,037 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$582 | Average$707 | FlexibilityNo cancel fee | On-time72% |