Spain

$249+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Dec 26 — Jan 21
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Find flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This Flysmarter deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:59 pmMCI - BCN
2 stops16h 31mBritish Airways
Wed 1/1412:30 pmBCN - MCI
1 stop15h 36mBritish Airways
Deal found 11/26$412
This Bookaflight.co.il deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bookaflight.co.il is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:47 pmMCI - MAD
1 stop13h 28mVirgin Atlantic
Wed 12/1011:15 amMAD - MCI
1 stop16h 53mVirgin Atlantic
Deal found 11/25$416
This Cheapflightsfares deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:49 amSTL - BCN
1 stop15h 11mIberia
Tue 12/912:30 pmBCN - STL
1 stop15h 08mIberia
Deal found 11/25$424
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:05 amMCI - BCN
1 stop18h 35mDelta
Thu 1/1510:15 amBCN - MCI
1 stop16h 04mDelta
Deal found 11/25$424
This Travelis deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelis is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:40 pmMCI - MAD
1 stop12h 15mBritish Airways
Wed 12/101:00 pmMAD - MCI
1 stop17h 45mBritish Airways
Deal found 11/25$425
This Finnair deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amMCI - BCN
1 stop20h 00mMultiple Airlines
Wed 1/1411:00 amBCN - MCI
1 stop19h 59mMultiple Airlines
Deal found 11/25$425
This eDestinos deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:48 pmSTL - MAD
2 stops14h 52mIberia
Mon 12/81:15 pmMAD - STL
1 stop14h 23mIberia
Deal found 11/26$425
This Delta deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:05 amSTL - BCN
1 stop18h 35mDelta
Fri 12/1210:55 amBCN - STL
1 stop14h 01mDelta
Deal found 11/26$426
This Delta deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:30 amSTL - BCN
1 stop16h 10mDelta
Thu 12/1110:55 amBCN - STL
1 stop19h 47mDelta
Deal found 11/26$427
This Delta deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:05 amMCI - BCN
1 stop18h 35mDelta
Fri 1/1610:55 amBCN - MCI
1 stop29h 29mDelta
Deal found 11/26$427
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:47 pmMCI - MAD
1 stop13h 28mDelta
Tue 12/910:00 amMAD - MCI
2 stops20h 47mDelta
Deal found 11/25$429
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:00 amMCI - MAD
1 stop19h 15mDelta
Thu 12/1111:15 amMAD - MCI
1 stop19h 32mDelta
Deal found 11/25$430

Cheap flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated November 26, 2025.

Round-trip from

$379
(eDestinos)

One-way from

$249
(Priceline)

Popular in

June

Cheapest in

February

Average price

$663
From Missouri to Spain
One-way flight from Missouri to Spain
Highest demand for flights based on searches. 24% potential increase in price ($290 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($36 potential savings vs. average RT price).
Average for round-trip flights in November 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Wed 12/31

6:00 am-9:00 am

1 stop20h 00m

Barcelona-El Prat

Wed 1/14

11:00 am-11:59 pm

1 stop19h 59m

$425

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Wed 12/31

5:43 am-8:40 am

1 stop19h 57m

Barcelona-El Prat

Thu 1/15

10:15 am-8:02 pm

2 stops16h 47m

$425

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Mon 1/19

8:13 am-5:45 am

1 stop14h 32m

Madrid Barajas

Wed 1/28

12:55 am-8:51 am

1 stop14h 56m

$429

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Mon 1/19

6:44 pm-4:55 pm

2 stops15h 11m

Madrid Barajas

Thu 1/29

12:40 pm-6:34 pm

1 stop12h 54m

$435

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Wed 1/28

12:49 pm-9:25 am

1 stop13h 36m

Madrid Barajas

Wed 2/11

12:40 pm-10:51 pm

1 stop17h 11m

$438

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Tue 1/13

5:50 am-8:40 am

1 stop19h 50m

Barcelona-El Prat

Tue 1/20

10:15 am-9:03 pm

2 stops17h 48m

$438

SpringfieldBarcelona

SGF - BCN

SGFBCN

Springfield-Branson

Mon 1/19

5:00 pm-8:00 am

2 stops56h 00m

Barcelona-El Prat

Mon 1/26

10:15 am-9:46 pm

2 stops18h 31m

$447

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 1/20

5:56 pm-5:40 pm

2 stops16h 44m

Madrid Barajas

Thu 1/29

11:15 am-5:50 pm

1 stop13h 35m

$448

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Thu 1/1

7:05 am-7:15 am

1 stop17h 10m

Barcelona-El Prat

Fri 1/16

10:55 am-12:42 pm

1 stop32h 47m

$450

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Thu 1/1

7:05 am-7:15 am

1 stop17h 10m

Barcelona-El Prat

Wed 1/14

10:55 am-12:44 pm

1 stop32h 49m

$450

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

Showing 1-10 of 54 results
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $451). Flying from Missouri to Spain in May is currently the most expensive (average of $837). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 26, 2025.

It’s optimal to fly from Missouri to Spain at noon. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from Missouri to Spain?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Spain. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Spain flight should consider departing on Wednesday mornings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Spain?

    Delta, British Airways, and Iberia can get you from Missouri to Spain in just under 15h 11m. Your travel time can differ by up to 4h 46m. There are 4414 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is British Airways, with whom users have recently found tickets for as low as $249. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $451). Flying from Missouri to Spain in May is currently the most expensive (average of $837). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Missouri to Spain

Discover the top 10 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$433Average$751FlexibilityNo cancel feeOn-time75%
DeltaCheapest$488Average$884FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$498Average$962FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$508Average$941FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$524Average$1,076FlexibilityNo cancel feeOn-time76%
American AirlinesCheapest$532Average$1,152FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$533Average$752FlexibilityNo cancel feeOn-time77%
IberiaCheapest$578Average$1,027FlexibilityNo cancel feeOn-time77%
Virgin AtlanticCheapest$582Average$707FlexibilityNo cancel feeOn-time72%
Air CanadaCheapest$624Average$1,091FlexibilityNo cancel feeOn-time67%

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