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$263+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
серп. 25 — вер. 11
пн 8/25
пн 9/1
1 adult, Economy
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Cheap flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated серпень 20, 2025.

Round-trip from

$438
(Delta)

One-way from

$263
(Mytrip)

Popular in

June

Cheapest in

February

Average price

$797
From Missouri to Spain
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One-way flight from Missouri to Spain
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Highest demand for flights based on searches. 31% potential increase in price ($446 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($51 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on серпень 20, 2025.

This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ср 11/1912:30 pmMCI - MAD
1 stop13h 30mDelta
ср 11/2611:00 amMAD - MCI
1 stop30h 33mDelta
Deal found 8/18$438
This Virgin Atlantic deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
вт 11/1810:35 amMCI - MAD
2 stops14h 25mVirgin Atlantic
вт 11/2510:00 amMAD - MCI
2 stops19h 21mVirgin Atlantic
Deal found 8/18$442
This Air Canada deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
сб 11/156:35 pmMCI - MAD
2 stops30h 25mAir Canada
ср 11/261:35 pmMAD - MCI
2 stops31h 46mAir Canada
Deal found 8/18$465
This KLM deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
пн 11/1710:35 amMCI - MAD
2 stops14h 25mKLM
вт 11/256:00 amMAD - MCI
2 stops17h 44mKLM
Deal found 8/18$468
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ср 11/124:27 pmSTL - MAD
2 stops15h 53mDelta
пт 11/286:00 amMAD - STL
2 stops24h 02mDelta
Deal found 8/20$481
This KLM deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
нд 11/212:37 pmMCI - BCN
1 stop13h 03mKLM
нд 11/1610:15 amBCN - MCI
1 stop14h 41mKLM
Deal found 8/19$484
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
чт 11/202:55 pmMCI - MAD
1 stop11h 05mDelta
пт 11/2811:00 amMAD - MCI
1 stop15h 01mDelta
Deal found 8/18$488
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
нд 11/25:15 amMCI - BCN
2 stops18h 45mDelta
нд 11/1610:55 amBCN - MCI
1 stop17h 09mDelta
Deal found 8/19$488
This KLM deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
пт 11/73:59 pmSTL - MAD
1 stop10h 31mMultiple Airlines
ср 11/1210:00 amMAD - STL
1 stop13h 40mMultiple Airlines
Deal found 8/19$488
This Iberia deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
нд 11/161:45 pmMCI - MAD
2 stops24h 05mIberia
вт 11/2511:35 amMAD - MCI
1 stop16h 48mIberia
Deal found 8/18$492
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
чт 11/206:30 amMCI - MAD
2 stops18h 30mDelta
ср 11/2611:00 amMAD - MCI
1 stop19h 57mDelta
Deal found 8/20$493
This Virgin Atlantic deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
пт 11/71:30 pmSTL - MAD
1 stop13h 00mVirgin Atlantic
ср 11/1210:00 amMAD - STL
2 stops17h 35mVirgin Atlantic
Deal found 8/19$493

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated серпень 20, 2025.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

пн 11/17

9:59 am-8:00 am

1 stop15h 01m

Madrid Barajas

ср 11/26

11:00 am-10:21 pm

1 stop18h 21m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

вт 11/18

12:30 pm-9:00 am

1 stop13h 30m

Madrid Barajas

ср 11/26

11:00 am-9:04 pm

1 stop17h 04m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

сб 11/15

5:00 pm-9:00 am

1 stop33h 00m

Madrid Barajas

вт 11/25

10:00 am-5:56 pm

1 stop14h 56m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

ср 11/19

10:35 am-9:00 am

1 stop15h 25m

Madrid Barajas

ср 11/26

11:00 am-9:04 pm

1 stop17h 04m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

ср 11/19

10:35 am-9:00 am

1 stop15h 25m

Madrid Barajas

вт 11/25

11:00 am-11:57 pm

1 stop19h 57m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

сб 11/15

5:00 pm-9:00 am

1 stop33h 00m

Madrid Barajas

чт 11/27

11:00 am-7:01 pm

1 stop15h 01m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

пн 11/17

6:42 pm-9:00 am

1 stop31h 18m

Madrid Barajas

пт 11/28

10:00 am-6:30 pm

1 stop15h 30m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

пн 11/17

10:35 am-9:00 am

1 stop15h 25m

Madrid Barajas

вт 11/25

11:00 am-10:21 pm

1 stop18h 21m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

нд 11/16

6:00 am-9:00 am

1 stop20h 00m

Madrid Barajas

пт 11/28

11:00 am-7:01 pm

1 stop15h 01m

$438

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

сб 11/15

5:00 pm-9:00 am

1 stop33h 00m

Madrid Barajas

ср 11/26

11:00 am-9:04 pm

1 stop17h 04m

$438

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated серпень 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Spain as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Spain?

    Air France, Delta, and KLM can get you from Missouri to Spain in just under 13h 03m. Your travel time can differ by up to 19h 57m. There are 4803 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $399. However, be on the lookout for offers from Air Canada and British Airways, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Spain

Discover the top 9 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated серпень 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$483Average$780FlexibilityNo cancel feeOn-time75%
DeltaCheapest$487Average$899FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$533Average$843FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$542Average$995FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$546Average$933FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$564Average$1,117FlexibilityNo cancel feeOn-time71%
IberiaCheapest$578Average$1,042FlexibilityNo cancel feeOn-time77%
LufthansaCheapest$605Average$1,125FlexibilityNo cancel feeOn-time76%
Air CanadaCheapest$629Average$1,108FlexibilityNo cancel feeOn-time67%

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