HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Spain

$286+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Spain with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated June 12, 2025.

Round-trip from

$519
(United Airlines)

One-way from

$286
(Mytrip)

Popular in

June

Cheapest in

February

Average price

$1,499
From Missouri to Spain
Search Deals
One-way flight from Missouri to Spain
Search Deals
Highest demand for flights based on searches. 31% potential increase in price ($437 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($49 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/217:30 amMCI - MAD
2 stops40h 10mAir Canada
Tue 9/3012:30 pmMAD - MCI
2 stops29h 07mAir Canada
Deal found 6/12$485
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/213:50 pmMCI - MAD
2 stops16h 45mDelta
Tue 9/3010:05 amMAD - MCI
1 stop18h 16mDelta
Deal found 6/12$506
This Finnair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/216:15 pmMCI - MAD
1 stop13h 05mMultiple Airlines
Tue 9/3011:30 amMAD - MCI
1 stop19h 29mMultiple Airlines
Deal found 6/12$512
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/116:00 amMCI - MAD
2 stops17h 40mUnited Airlines
Wed 8/2012:45 pmMAD - MCI
2 stops32h 35mUnited Airlines
Deal found 6/10$519
This KLM deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1110:44 amMCI - MAD
1 stop15h 51mKLM
Wed 8/2010:05 amMAD - MCI
1 stop20h 49mKLM
Deal found 6/10$542
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/241:30 pmSTL - BCN
1 stop11h 20mAir Canada
Wed 10/112:10 pmBCN - STL
1 stop14h 47mAir Canada
Deal found 6/11$544
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/26:16 pmMCI - MAD
2 stops18h 39mBritish Airways
Fri 9/124:00 pmMAD - MCI
1 stop32h 22mBritish Airways
Deal found 6/10$546
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/231:30 pmSTL - BCN
1 stop11h 20mUnited Airlines
Tue 10/712:10 pmBCN - STL
2 stops29h 39mUnited Airlines
Deal found 6/12$555
This Air Canada deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/217:30 amMCI - BCN
2 stops17h 20mAir Canada
Tue 10/712:10 pmBCN - MCI
2 stops36h 16mAir Canada
Deal found 6/9$559
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/61:30 pmSTL - MAD
1 stop10h 10mUnited Airlines
Fri 10/1712:45 pmMAD - STL
2 stops29h 04mUnited Airlines
Deal found 6/12$559
This Air France deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/162:15 pmMCI - MAD
2 stops14h 05mAir France
Tue 9/3010:05 amMAD - MCI
1 stop20h 52mAir France
Deal found 6/11$561
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:45 amSGF - MAD
2 stops17h 20mUnited Airlines
Wed 11/121:20 pmMAD - SGF
2 stops35h 26mUnited Airlines
Deal found 6/10$568

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Mon 8/11

6:00 am-6:40 am

2 stops17h 40m

Madrid Barajas

Wed 8/20

12:45 pm-2:20 pm

2 stops32h 35m

$519

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Mon 8/11

10:44 am-9:35 am

1 stop15h 51m

Madrid Barajas

Wed 8/20

10:05 am-11:54 pm

1 stop20h 49m

$542

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Wed 9/24

1:30 pm-7:50 am

1 stop11h 20m

Barcelona-El Prat

Wed 10/1

12:10 pm-7:57 pm

1 stop14h 47m

$544

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 9/2

6:16 pm-7:55 pm

2 stops18h 39m

Madrid Barajas

Fri 9/12

4:00 pm-5:22 pm

1 stop32h 22m

$546

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Mon 8/11

10:44 am-9:35 am

1 stop15h 51m

Madrid Barajas

Wed 8/20

12:40 pm-11:05 pm

2 stops17h 25m

$547

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 9/23

1:30 pm-7:50 am

1 stop11h 20m

Barcelona-El Prat

Tue 10/7

12:10 pm-10:49 am

2 stops29h 39m

$555

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Mon 10/6

1:30 pm-6:40 am

1 stop10h 10m

Madrid Barajas

Fri 10/17

12:45 pm-10:49 am

2 stops29h 04m

$559

SpringfieldMadrid

SGF - MAD

SGFMAD

Springfield-Branson

Wed 10/22

7:45 am-8:05 am

2 stops17h 20m

Madrid Barajas

Wed 11/12

1:20 pm-5:46 pm

2 stops35h 26m

$568

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Sat 10/11

3:23 pm-6:40 am

2 stops32h 17m

Madrid Barajas

Tue 10/21

12:30 pm-2:27 pm

2 stops32h 57m

$570

SpringfieldMadrid

SGF - MAD

SGFMAD

Springfield-Branson

Wed 10/22

12:10 pm-9:05 am

1 stop13h 55m

Madrid Barajas

Wed 11/12

11:35 am-8:32 pm

1 stop15h 57m

$580

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,057). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Spain as you normally would.

Rainfall in Spain by month

Plan your trip to Spain by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

Temperature in Spain by month

Plan your trip to Spain by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated June 12, 2025.
Peruse reviews from past customers who have flown with Delta, KLM and Finnair from Missouri to Spain to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,358 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Finnair
7.6
Good
1,290 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air France
7.5
Good
1,463 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is Air Canada, with whom users have recently found tickets for as low as $463. However, be on the lookout for offers from Finnair and Lufthansa, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,057). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Heathrow flights
John F Kennedy Intl to Charles de Gaulle flights
Newark to Charles de Gaulle flights
John F Kennedy Intl to Leonardo da Vinci/Fiumicino flights
Newark to Heathrow flights
John F Kennedy Intl to Gatwick flights
Newark to Leonardo da Vinci/Fiumicino flights
Newark to Orly flights
John F Kennedy Intl to Istanbul flights
Newark to Athens flights
John F Kennedy Intl to Barcelona-El Prat flights
John F Kennedy Intl to Athens flights
Los Angeles to Heathrow flights
Boston to Heathrow flights
John F Kennedy Intl to Orly flights
John F Kennedy Intl to Lisbon flights
LaGuardia to Heathrow flights
LaGuardia to Charles de Gaulle flights
Dulles Intl to Heathrow flights
John F Kennedy Intl to London City flights
Newark to Lisbon flights
Newark to Gatwick flights
Newark to Barcelona-El Prat flights
Miami to Madrid flights
Dulles Intl to Charles de Gaulle flights
Seattle to Heathrow flights
John F Kennedy Intl to Madrid flights
Newark to Madrid flights
San Francisco to Heathrow flights
O'Hare Intl to Heathrow flights
Newark to Dublin flights
Dallas/Fort Worth to Heathrow flights
John F Kennedy Intl to Malpensa flights
John F Kennedy Intl to Frederic Chopin flights
Baltimore to Heathrow flights
O'Hare Intl to Charles de Gaulle flights
O'Hare Intl to Leonardo da Vinci/Fiumicino flights
Newark to Malpensa flights
LaGuardia to Leonardo da Vinci/Fiumicino flights
Boston to Charles de Gaulle flights
Boston to Leonardo da Vinci/Fiumicino flights
John F Kennedy Intl to Dublin flights
Los Angeles to Charles de Gaulle flights
Boston to Gatwick flights
LaGuardia to Gatwick flights
Los Angeles to Leonardo da Vinci/Fiumicino flights
Dulles Intl to Leonardo da Vinci/Fiumicino flights
Boston to Lisbon flights
John F Kennedy Intl to Vicenza flights
Newark to Frankfurt flights

Top 9 airlines flying from Missouri to Spain

Discover the top 9 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$437Average$1,042FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$468Average$821FlexibilityNo cancel feeOn-time75%
LufthansaCheapest$530Average$1,111FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$542Average$1,026FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$544Average$1,060FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$545Average$915FlexibilityNo cancel feeOn-time70%
IberiaCheapest$566Average$1,040FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$650Average$907FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$673Average$1,091FlexibilityNo cancel feeOn-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.