How long is the flight from Missouri to Spain?

Lufthansa, Air Canada, and United Airlines can get you from Missouri to Spain in just under 14h 53m. Your travel time can differ by up to 17h 02m. There are 4414 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Missouri to Spain one-way?

The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $322. However, be on the lookout for offers from United Airlines and Lufthansa, as they are both options that can get you from Missouri to Spain for a low price.

In terms of precipitation, rainfall in Spain ranges from 0.8 - 3.6 inches per month. October is typically the wettest month, when rainfall can reach 3.6 in. July is typically the driest time to visit Spain when rainfall is around 0.8 in.

If weather is an important factor for your trip to Spain, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

What is the cheapest time of day to fly from MO to ES?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Spain as you normally would.

Can I find deals for flights from Missouri to Spain that include hotel bookings?

Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Spain?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

Can I find deals for business class flights from Missouri to Spain?

Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$210+ Flights from Missouri to Spain

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Cheap flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Tue 12/309:47 amSTL - MAD

1 stop16h 28mVirgin Atlantic

Thu 1/1511:15 amMAD - STL

1 stop13h 35mVirgin Atlantic

Deal found 12/28

$627

Mon 12/296:35 pmSTL - MAD

2 stops16h 15mLufthansa

Tue 1/1311:15 amMAD - STL

1 stop19h 44mLufthansa

Deal found 12/28

$632

Tue 12/306:35 pmSTL - MAD

2 stops30h 25mUnited Airlines

Thu 1/151:35 pmMAD - STL

2 stops38h 38mUnited Airlines

Deal found 12/28

$644

Mon 12/294:55 pmSTL - MAD

1 stop32h 05mKLM

Tue 1/1311:15 amMAD - STL

1 stop28h 38mKLM

Deal found 12/27

$651

Mon 12/296:30 amSTL - MAD

2 stops19h 45mUnited Airlines

Tue 1/1311:15 amMAD - STL

2 stops18h 43mUnited Airlines

Deal found 12/28

$653

Wed 12/3112:47 pmMCI - BCN

2 stops15h 18mLufthansa

Wed 1/1411:55 amBCN - MCI

2 stops17h 04mLufthansa

Deal found 12/27

$661

Tue 12/301:54 pmSTL - MAD

1 stop11h 56mAmerican Airlines

Thu 1/151:15 pmMAD - STL

1 stop16h 29mAmerican Airlines

Deal found 12/28

$662

Tue 12/307:00 amSTL - MAD

1 stop19h 15mDelta

Thu 1/156:00 amMAD - STL

2 stops18h 50mDelta

Deal found 12/28

$663

Mon 12/296:35 pmSTL - MAD

1 stop28h 10mBritish Airways

Tue 1/1312:50 pmMAD - STL

2 stops36h 24mBritish Airways

Deal found 12/27

$669

Wed 12/316:00 amMCI - BCN

2 stops22h 10mBritish Airways

Wed 1/1412:30 pmBCN - MCI

1 stop15h 36mBritish Airways

Deal found 12/27

$673

Sat 12/276:35 pmSTL - MAD

2 stops39h 05mUnited Airlines

Tue 1/1311:15 amMAD - STL

2 stops18h 43mUnited Airlines

Deal found 12/25

$679

Fri 12/261:49 pmMCI - MAD

1 stop12h 06mMultiple Airlines

Fri 1/21:15 pmMAD - MCI

1 stop15h 28mMultiple Airlines

Deal found 12/25

$998

Best flights from Missouri to Spain
Discover carefully curated flight deals from Missouri to Spain that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Tue 1/2711:22 amSTL - MAD

1 stop14h 53mLufthansa

Tue 2/311:15 amMAD - STL

1 stop19h 44mLufthansa

Deal found 12/28

$445

Fri 3/67:41 amSTL - BCN

2 stops18h 54mAir Canada

Thu 3/1212:35 pmBCN - STL

2 stops32h 08mAir Canada

Deal found 12/27

$468

Tue 2/106:40 pmSTL - BCN

2 stops31h 55mUnited Airlines

Tue 2/171:35 pmBCN - STL

2 stops38h 30mUnited Airlines

Deal found 12/27

$468

Sat 1/245:49 pmMCI - BCN

2 stops17h 06mBritish Airways

Sat 1/3112:30 pmBCN - MCI

1 stop15h 36mBritish Airways

Deal found 12/26

$473

Mon 2/91:56 pmMCI - BCN

1 stop11h 54mMultiple Airlines

Mon 2/1610:40 amBCN - MCI

1 stop18h 55mMultiple Airlines

Deal found 12/26

$475

Thu 1/222:12 pmMCI - VLC

2 stops20h 43mAir France

Tue 1/276:00 amVLC - MCI

2 stops18h 00mAir France

Deal found 12/25

$477

Fri 1/239:57 amMCI - MAD

1 stop15h 03mKLM

Thu 2/510:00 amMAD - MCI

1 stop16h 19mKLM

Deal found 12/26

$480

Tue 4/1412:22 pmMCI - MAD

1 stop16h 53mDelta

Tue 4/286:00 amMAD - MCI

2 stops20h 19mDelta

Deal found 12/27

$491

Wed 4/812:41 pmSGF - MAD

1 stop12h 14mAmerican Airlines

Fri 4/1712:40 pmMAD - SGF

1 stop14h 37mAmerican Airlines

Deal found 12/27

$538

Fri 2/2012:51 pmMCI - AGP

2 stops21h 04mIberia

Tue 2/245:50 pmAGP - MCI

2 stops34h 56mIberia

Deal found 12/25

$735

Sat 2/73:00 pmMCI - BCN

2 stops35h 35mUnited Airlines

Mon 2/161:35 pmBCN - MCI

2 stops33h 10mUnited Airlines

Deal found 12/27

$468

Sun 2/14:05 pmSTL - BCN

2 stops34h 30mAir Canada

Tue 2/171:35 pmBCN - STL

2 stops38h 30mAir Canada

Deal found 12/26

$470

Sun 1/255:49 pmMCI - BCN

2 stops16h 11mBritish Airways

Sat 2/712:30 pmBCN - MCI

1 stop15h 36mBritish Airways

Deal found 12/27

$473

Fri 1/236:30 pmMCI - BCN

2 stops16h 05mLufthansa

Sat 1/316:50 amBCN - MCI

2 stops22h 09mLufthansa

Deal found 12/26

$476

Sat 1/249:57 amMCI - MAD

1 stop15h 03mKLM

Fri 2/610:00 amMAD - MCI

2 stops19h 02mKLM

Deal found 12/27

$480

Sun 2/19:33 amSTL - BCN

1 stop16h 27mMultiple Airlines

Tue 2/1710:40 amBCN - STL

1 stop15h 45mMultiple Airlines

Deal found 12/26

$484

Sun 3/156:10 amSTL - MAD

1 stop18h 50mDelta

Tue 3/2411:00 amMAD - STL

2 stops28h 05mDelta

Deal found 12/26

$492

Sat 2/217:55 amSGF - BCN

2 stops17h 25mUnited Airlines

Mon 3/21:35 pmBCN - SGF

2 stops39h 24mUnited Airlines

Deal found 12/26

$469

Thu 3/56:00 amSTL - MAD

2 stops22h 55mBritish Airways

Wed 3/181:45 pmMAD - STL

1 stop16h 03mBritish Airways

Deal found 12/28

$476

Mon 2/236:27 pmMCI - MAD

2 stops22h 08mLufthansa

Sun 3/15:55 amMAD - MCI

2 stops23h 04mLufthansa

Deal found 12/27

$477

Tue 3/106:00 amMCI - BCN

1 stop20h 00mMultiple Airlines

Fri 3/2011:00 amBCN - MCI

1 stop19h 39mMultiple Airlines

Deal found 12/26

$484

Sat 2/216:00 amSGF - BCN

1 stop19h 40mKLM

Mon 3/210:15 amBCN - SGF

2 stops18h 32mKLM

Deal found 12/26

$489

Fri 1/238:00 amMCI - BCN

2 stops18h 00mUnited Airlines

Tue 1/271:35 pmBCN - MCI

2 stops32h 35mUnited Airlines

Deal found 12/26

$469

Fri 3/67:41 amSTL - BCN

2 stops18h 54mAir Canada

Thu 3/2612:35 pmBCN - STL

2 stops38h 32mAir Canada

Deal found 12/27

$518

Wed 2/49:33 amSTL - BCN

1 stop16h 27mBritish Airways

Wed 2/1112:30 pmBCN - STL

1 stop17h 14mBritish Airways

Deal found 12/26

$482

Tue 2/106:00 amSTL - BCN

1 stop20h 00mMultiple Airlines

Tue 2/1711:00 amBCN - STL

2 stops19h 18mMultiple Airlines

Deal found 12/27

$489

Sat 1/248:00 amMCI - BCN

2 stops18h 00mUnited Airlines

Sat 1/311:35 pmBCN - MCI

2 stops37h 12mUnited Airlines

Deal found 12/26

$469

Mon 3/165:15 pmSTL - MAD

1 stop31h 45mDelta

Tue 3/249:00 amMAD - STL

1 stop17h 43mDelta

Deal found 12/26

$569

Tue 4/73:56 pmSGF - MAD

2 stops17h 49mAir France

Fri 4/246:00 amMAD - SGF

2 stops19h 13mAir France

Deal found 12/26

$627

Fri 1/236:06 amMCI - BCN

1 stop19h 54mBritish Airways

Sat 1/3110:40 amBCN - MCI

1 stop19h 32mBritish Airways

Deal found 12/26

$482

Last-minute flights from Missouri to Spain
Discover last-minute flight deals from Missouri to Spain. Data last updated December 28, 2025 and is based on user searches.

Thu 1/222:12 pmMCI - VLC

2 stops20h 43mAir France

Tue 1/276:00 amVLC - MCI

2 stops18h 00mAir France

Deal found 12/25

$477

Fri 1/238:00 amMCI - BCN

2 stops18h 00mUnited Airlines

Tue 1/271:35 pmBCN - MCI

2 stops32h 35mUnited Airlines

Deal found 12/26

$469

Fri 1/2311:29 amMCI - MAD

2 stops14h 46mUnited Airlines

Tue 1/271:35 pmMAD - MCI

2 stops31h 52mUnited Airlines

Deal found 12/26

$474

Fri 1/236:30 pmMCI - BCN

2 stops16h 05mLufthansa

Sat 1/316:50 amBCN - MCI

2 stops22h 09mLufthansa

Deal found 12/26

$476

Fri 1/2311:29 amMCI - MAD

2 stops14h 46mUnited Airlines

Thu 2/511:15 amMAD - MCI

2 stops17h 44mUnited Airlines

Deal found 12/26

$480

Sat 1/245:09 pmMCI - MAD

2 stops31h 51mVirgin Atlantic

Fri 2/610:00 amMAD - MCI

2 stops17h 02mVirgin Atlantic

Deal found 12/27

$466

Sun 1/255:49 pmMCI - BCN

2 stops16h 11mBritish Airways

Sat 2/712:30 pmBCN - MCI

1 stop15h 36mBritish Airways

Deal found 12/27

$473

Mon 1/2611:22 amSTL - MAD

1 stop14h 53mLufthansa

Mon 2/211:15 amMAD - STL

1 stop19h 44mLufthansa

Deal found 12/27

$437

Mon 1/268:30 amSTL - MAD

2 stops16h 30mUnited Airlines

Mon 2/21:35 pmMAD - STL

2 stops36h 52mUnited Airlines

Deal found 12/27

$473

Mon 1/2612:11 pmSTL - MAD

2 stops16h 44mBritish Airways

Mon 2/21:15 pmMAD - STL

1 stop16h 29mBritish Airways

Deal found 12/27

$476

Tue 1/2711:22 amSTL - MAD

1 stop14h 53mLufthansa

Tue 2/311:15 amMAD - STL

1 stop19h 44mLufthansa

Deal found 12/28

$445

Fri 1/303:50 pmSTL - BCN

1 stop21h 00mUnited Airlines

Tue 2/31:35 pmBCN - STL

2 stops31h 55mUnited Airlines

Deal found 12/25

$480

One-way flights from Missouri to Spain
Search for one-way flight options from Missouri to Spain. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Tue 4/2810:00 pmSTL - MAD

1 stop14h 55mBritish Airways

Deal found 12/27

$210

Sun 5/310:00 pmSTL - MAD

1 stop12h 35mBritish Airways

Deal found 12/27

$223

Tue 4/286:00 amSTL - MAD

2 stops18h 50mDelta

Deal found 12/27

$231

Fri 2/611:18 amSTL - BCN

2 stops42h 32mMultiple Airlines

Deal found 12/26

$235

Mon 4/271:11 pmSTL - MAD

2 stops15h 09mAir France

Deal found 12/27

$235

Mon 2/210:16 amSTL - BCN

2 stops42h 24mMultiple Airlines

Deal found 12/26

$240

Wed 4/2911:14 amSTL - MAD

1 stop19h 11mBritish Airways

Deal found 12/27

$247

Fri 5/110:00 pmSTL - MAD

1 stop28h 35mBritish Airways

Deal found 12/27

$273

Thu 4/309:15 amSTL - MAD

1 stop14h 35mAmerican Airlines

Deal found 12/27

$281

Wed 2/45:42 pmSTL - BCN

2 stops40h 23mMultiple Airlines

Deal found 12/26

$291

Sun 5/36:32 amSTL - MAD

2 stops19h 58mDelta

Deal found 12/27

$302

Tue 2/35:42 pmSTL - BCN

3 stops37h 23mMultiple Airlines

Deal found 12/26

$313

Find flight deals from Missouri to Spain

Round-trip from	$437 (Kiwi.com)
One-way from	$210 (oojo)
Popular in	June
Cheapest in	February
Average price	$835

From Missouri to Spain

Search Deals

One-way flight from Missouri to Spain

Search Deals

Highest demand for flights based on searches. 23% potential increase in price ($278 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 1/27

11:22 am-9:15 am

1 stop14h 53m

Madrid Barajas

Tue 2/3

11:15 am-11:59 pm

1 stop19h 44m

$445

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Fri 3/6

7:41 am-9:35 am

2 stops18h 54m

Barcelona-El Prat

Thu 3/12

12:35 pm-2:43 pm

2 stops32h 08m

$468

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Tue 2/10

6:40 pm-9:35 am

2 stops31h 55m

Barcelona-El Prat

Tue 2/17

1:35 pm-9:05 pm

2 stops38h 30m

$468

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Sat 2/7

3:00 pm-9:35 am

2 stops35h 35m

Barcelona-El Prat

Mon 2/16

1:35 pm-3:45 pm

2 stops33h 10m

$468

SpringfieldBarcelona

SGF - BCN

SGFBCN

Springfield-Branson

Sat 2/21

7:55 am-8:20 am

2 stops17h 25m

Barcelona-El Prat

Mon 3/2

1:35 pm-9:59 pm

2 stops39h 24m

$469

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Fri 1/23

8:00 am-9:00 am

2 stops18h 00m

Barcelona-El Prat

Tue 1/27

1:35 pm-3:10 pm

2 stops32h 35m

$469

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Sat 1/24

8:00 am-9:00 am

2 stops18h 00m

Barcelona-El Prat

Sat 1/31

1:35 pm-7:47 pm

2 stops37h 12m

$469

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

Sun 2/1

4:05 pm-9:35 am

2 stops34h 30m

Barcelona-El Prat

Tue 2/17

1:35 pm-9:05 pm

2 stops38h 30m

$470

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Sat 1/24

5:49 pm-5:55 pm

2 stops17h 06m

Barcelona-El Prat

Sat 1/31

12:30 pm-9:06 pm

1 stop15h 36m

$473

Kansas CityBarcelona

MCI - BCN

MCIBCN

Kansas City

Sun 1/25

5:49 pm-5:00 pm

2 stops16h 11m

Barcelona-El Prat

Sat 2/7

12:30 pm-9:06 pm

1 stop15h 36m

$473

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $449). Flying from Missouri to Spain in May is currently the most expensive (average of $823). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

How long is the flight from Missouri to Spain?
Lufthansa, Air Canada, and United Airlines can get you from Missouri to Spain in just under 14h 53m. Your travel time can differ by up to 17h 02m. There are 4414 mi between Missouri and Spain. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Missouri to Spain one-way?
The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $322. However, be on the lookout for offers from United Airlines and Lufthansa, as they are both options that can get you from Missouri to Spain for a low price.
Can I find deals for flights from Missouri to Spain that include hotel bookings?
Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Spain?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.
Can I find deals for business class flights from Missouri to Spain?
Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Spain?
Currently, January is the cheapest month in which you can book a flight from Missouri to Spain (average of $449). Flying from Missouri to Spain in May is currently the most expensive (average of $823). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 10 airlines flying from Missouri to Spain

Airline	Cheapest	Average	Flexibility	On-time
KLM	Cheapest$433	Average$763	FlexibilityNo cancel fee	On-time75%
Virgin Atlantic	Cheapest$437	Average$756	FlexibilityNo cancel fee	On-time72%
British Airways	Cheapest$483	Average$891	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$487	Average$873	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$488	Average$1,098	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$498	Average$956	FlexibilityNo cancel fee	On-time69%
Lufthansa	Cheapest$524	Average$1,066	FlexibilityNo cancel fee	On-time76%
Air France	Cheapest$533	Average$752	FlexibilityNo cancel fee	On-time77%
Iberia	Cheapest$578	Average$1,013	FlexibilityNo cancel fee	On-time77%
Air Canada	Cheapest$624	Average$1,082	FlexibilityNo cancel fee	On-time67%

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$210+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Spain

Cheapest flights from Missouri to SpainExplore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated December 28, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missouri to Spain?

What are the cheapest airlines to fly from Missouri to Spain one-way?

Can I find deals for flights from Missouri to Spain that include hotel bookings?

How can I find direct flights from Missouri to Spain?

Can I find deals for business class flights from Missouri to Spain?

What is the cheapest month to book a flight from Missouri to Spain?

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Missouri to Spain

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Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.