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South Carolina

$346+ Cheap flights from Manchester (MAN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated September 11, 2025.

Round-trip from

$734
(TravelUp)

One-way from

$346
(Kiwi.com)

Popular in

July

Cheapest in

January

Average price

$892
From Manchester to South Carolina
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One-way flight from Manchester to South Carolina
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Highest demand for flights based on searches. 9% potential increase in price ($98 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This TravelUp deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/612:35 pmMAN - CHS
1 stop13h 16mVirgin Atlantic
Tue 10/1412:54 pmCHS - MAN
1 stop14h 41mVirgin Atlantic
Deal found 9/10$734
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:05 amMAN - CAE
2 stops32h 44mUnited Airlines
Tue 9/3010:24 amCAE - MAN
2 stops19h 16mUnited Airlines
Deal found 9/11$748
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:05 amMAN - MYR
3 stops47h 06mMultiple Airlines
Tue 11/41:43 pmMYR - MAN
2 stops15h 52mMultiple Airlines
Deal found 9/9$788
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/167:55 amMAN - MYR
2 stops20h 15mAmerican Airlines
Fri 9/265:36 pmMYR - MAN
2 stops18h 44mAmerican Airlines
Deal found 9/9$805
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/162:15 pmMAN - MYR
2 stops24h 55mDelta
Fri 9/2610:55 amMYR - MAN
1 stop16h 40mDelta
Deal found 9/9$806
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:35 pmMAN - CAE
1 stop30h 51mDelta
Tue 9/303:06 pmCAE - MAN
1 stop12h 29mDelta
Deal found 9/11$806
This TravelUp deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1511:55 amMAN - MYR
1 stop17h 04mVirgin Atlantic
Tue 11/46:58 pmMYR - MAN
2 stops30h 42mVirgin Atlantic
Deal found 9/9$843
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/263:05 pmMAN - MYR
3 stops37h 06mMultiple Airlines
Sun 11/25:47 amMYR - MAN
3 stops25h 38mMultiple Airlines
Deal found 9/11$883
This Virgin Atlantic deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:55 amMAN - CAE
2 stops15h 33mVirgin Atlantic
Tue 9/305:13 pmCAE - MAN
1 stop10h 22mVirgin Atlantic
Deal found 9/11$899
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:20 pmMAN - CLT
3 stops28h 20mMultiple Airlines
Sun 10/1910:19 amCLT - MAN
2 stops16h 16mMultiple Airlines
Deal found 9/10$910
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:55 pmMAN - CLT
2 stops34h 34mMultiple Airlines
Thu 10/3010:19 amCLT - MAN
2 stops20h 16mMultiple Airlines
Deal found 9/11$916
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/68:25 pmMAN - CHS
3 stops27h 16mMultiple Airlines
Thu 10/910:11 amCHS - MAN
3 stops21h 14mMultiple Airlines
Deal found 9/11$917

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Mon 10/6

12:35 pm-8:51 pm

1 stop13h 16m

Charleston

Tue 10/14

12:54 pm-8:35 am

1 stop14h 41m

$734

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Thu 3/5

6:00 am-11:52 pm

2 stops22h 52m

Savannah/Hilton Head

Mon 3/9

3:30 pm-12:20 pm

2 stops16h 50m

$736

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Fri 9/26

6:05 am-9:49 am

2 stops32h 44m

Columbia Metropolitan

Tue 9/30

10:24 am-10:40 am

2 stops19h 16m

$748

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 3/4

6:10 am-9:22 pm

2 stops20h 12m

Charleston

Sun 3/8

8:44 pm-3:35 pm

2 stops14h 51m

$762

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Thu 3/5

5:40 am-9:14 pm

2 stops20h 34m

Myrtle Beach Intl

Mon 3/9

6:37 pm-2:00 pm

2 stops15h 23m

$762

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Fri 3/6

11:50 am-11:36 pm

2 stops16h 46m

Myrtle Beach Intl

Tue 3/10

6:37 pm-4:30 pm

2 stops17h 53m

$763

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Wed 10/15

6:05 am-12:11 am

3 stops47h 06m

Myrtle Beach Intl

Tue 11/4

1:43 pm-10:35 am

2 stops15h 52m

$788

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Thu 3/5

1:30 pm-11:35 pm

1 stop15h 05m

Myrtle Beach Intl

Mon 3/9

6:45 pm-6:40 pm

2 stops19h 55m

$799

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Thu 3/5

1:30 pm-8:48 pm

1 stop12h 18m

Savannah/Hilton Head

Mon 3/9

6:50 pm-6:40 pm

2 stops19h 50m

$799

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Fri 3/6

1:25 pm-10:08 am

1 stop25h 43m

Myrtle Beach Intl

Tue 3/10

11:10 am-6:40 am

2 stops15h 30m

$805

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 37 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Manchester to South Carolina (average of $217). Flying from Manchester to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    Located just 8.9 mi from the city center, Manchester (MAN) is the airport most travelers will use when flying to South Carolina from Manchester.

  • How long is the flight from Manchester to South Carolina?

    For as low as $734, Virgin Atlantic can have you in South Carolina from Manchester in 13h 16m. There are 3948 mi between Manchester and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Manchester to South Carolina?

    The most popular route from Manchester to South Carolina is Manchester - Charlotte Douglas. You may also consider Manchester - Charleston or Manchester - Savannah/Hilton Head.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Manchester to South Carolina (average of $217). Flying from Manchester to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to South Carolina

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