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South Carolina

$334+ Cheap flights from Manchester (MAN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:50 pm
MAN
-
CLT
3 stops36h 03m
Multiple Airlines
Fri 3/277:00 am
CLT
-
MAN
2 stops23h 45m
Multiple Airlines
Deal found 1/28$700
This Booking.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:55 pm
MAN
-
CLT
2 stops30h 58m
Multiple Airlines
Fri 3/209:18 am
CLT
-
MAN
2 stops30h 17m
Multiple Airlines
Deal found 1/27$759
This The Travel House deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure The Travel House is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:25 pm
MAN
-
CLT
2 stops31h 24m
Scandinavian Airlines
Tue 5/126:00 am
CLT
-
MAN
2 stops21h 55m
Scandinavian Airlines
Deal found 1/26$820
This The Travel House deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure The Travel House is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:25 pm
MAN
-
CHS
2 stops30h 09m
Scandinavian Airlines
Sat 5/166:00 am
CHS
-
MAN
2 stops45h 55m
Scandinavian Airlines
Deal found 1/27$821
This TravelUp deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:25 am
MAN
-
CAE
2 stops15h 02m
Virgin Atlantic
Mon 3/212:45 pm
CAE
-
MAN
2 stops14h 10m
Virgin Atlantic
Deal found 1/26$831
This The Travel House deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure The Travel House is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:35 am
MAN
-
MYR
2 stops19h 04m
Scandinavian Airlines
Thu 10/110:55 am
MYR
-
MAN
2 stops41h 00m
Scandinavian Airlines
Deal found 1/26$834
This The Travel House deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure The Travel House is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:35 am
MAN
-
CLT
2 stops17h 48m
Scandinavian Airlines
Sat 5/306:00 am
CLT
-
MAN
2 stops21h 55m
Scandinavian Airlines
Deal found 1/27$835
This TravelUp deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:00 am
MAN
-
CAE
2 stops21h 44m
Lufthansa
Thu 3/197:39 pm
CAE
-
MAN
2 stops23h 41m
Lufthansa
Deal found 1/26$838
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2311:50 am
MAN
-
CHS
2 stops17h 01m
American Airlines
Mon 3/22:42 pm
CHS
-
MAN
2 stops16h 03m
American Airlines
Deal found 1/26$845
This Travcart deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travcart is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/121:30 pm
MAN
-
CHS
1 stop13h 01m
Virgin Atlantic
Thu 3/195:56 pm
CHS
-
MAN
1 stop12h 34m
Virgin Atlantic
Deal found 1/26$846
This Lufthansa deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:25 am
MAN
-
GSP
2 stops18h 26m
Lufthansa
Fri 3/202:52 pm
GSP
-
MAN
2 stops15h 38m
Lufthansa
Deal found 1/27$846
This TravelUp deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:40 am
MAN
-
MYR
1 stop17h 59m
Virgin Atlantic
Tue 9/226:45 pm
MYR
-
MAN
1 stop31h 30m
Virgin Atlantic
Deal found 1/27$848

Find flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated January 28, 2026.

Most accurate provider

AranGrant
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$700
(Mytrip)

One-way from

$334
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$847
Provider with most accurate pricing for Manchester-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Myrtle Beach Intl flights.
Search Deals
From Manchester to South Carolina
Search Deals
One-way flight from Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Tue 3/17

3:50 pm-11:53 pm

3 stops36h 03m

Charlotte Douglas

Fri 3/27

7:00 am-10:45 am

2 stops23h 45m

$700

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Fri 3/13

8:55 pm-11:53 pm

2 stops30h 58m

Charlotte Douglas

Fri 3/20

9:18 am-7:35 pm

2 stops30h 17m

$759

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Fri 5/1

8:25 pm-9:34 pm

2 stops30h 09m

Charleston

Sat 5/16

6:00 am-8:55 am

2 stops45h 55m

$821

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Mon 2/23

10:25 am-8:27 pm

2 stops15h 02m

Columbia Metropolitan

Mon 3/2

12:45 pm-7:55 am

2 stops14h 10m

$831

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Wed 5/20

9:35 am-10:23 pm

2 stops17h 48m

Charlotte Douglas

Sat 5/30

6:00 am-8:55 am

2 stops21h 55m

$835

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Thu 3/12

6:00 am-11:44 pm

2 stops21h 44m

Columbia Metropolitan

Thu 3/19

7:39 pm-11:20 pm

2 stops23h 41m

$838

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Fri 3/13

6:25 am-8:51 pm

2 stops18h 26m

Greenville

Fri 3/20

2:52 pm-10:30 am

2 stops15h 38m

$846

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Mon 2/23

9:30 am-11:44 pm

2 stops19h 14m

Columbia Metropolitan

Mon 3/2

7:36 pm-12:20 pm

2 stops35h 44m

$849

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Fri 3/13

6:10 am-5:05 pm

2 stops14h 55m

Myrtle Beach Intl

Fri 5/1

3:14 pm-5:20 pm

2 stops21h 06m

$850

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Thu 3/12

8:50 am-10:28 pm

2 stops17h 38m

Myrtle Beach Intl

Thu 3/19

6:22 pm-4:30 pm

2 stops18h 08m

$853

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 49 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of $699). Flying from Manchester to South Carolina in June is currently the most expensive (average of $834). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Manchester to South Carolina?

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    Located just 8.9 mi from the city center, Manchester (MAN) is the airport most travelers will use when flying to South Carolina from Manchester.

  • How long is the flight from Manchester to South Carolina?

    For as low as $831, Scandinavian Airlines can have you in South Carolina from Manchester in 15h 02m. There are 3940 mi between Manchester and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Manchester to South Carolina?

    The most popular route from Manchester to South Carolina is Manchester - Charlotte Douglas. You may also consider Manchester - Charleston or Manchester - Myrtle Beach Intl.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of $699). Flying from Manchester to South Carolina in June is currently the most expensive (average of $834). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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