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Sioux Falls

$146+ Cheap flights from Harrisburg to Sioux Falls (MDT - FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — FSD
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Harrisburg to Sioux Falls

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$259
(American Airlines)

One-way from

$146
(Kiwi.com)

Popular in

May

Cheapest in

April

Average price

$543
From Harrisburg to Sioux Falls Joe Foss Field
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One-way flight from Harrisburg to Sioux Falls Joe Foss Field
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Highest demand for flights based on searches. 7% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($39 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Harrisburg to Sioux Falls

Cheapest flights from Harrisburg to Sioux Falls
Explore the most affordable flight options available from Harrisburg to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:51 amMDT - FSD
1 stop6h 51mAmerican Airlines
Sat 10/181:27 pmFSD - MDT
1 stop8h 46mAmerican Airlines
Deal found 9/10$259
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:24 pmMDT - FSD
1 stop5h 32mUnited Airlines
Thu 1/13:08 pmFSD - MDT
1 stop7h 59mUnited Airlines
Deal found 9/10$339
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:15 amMDT - FSD
2 stops9h 12mUnited Airlines
Mon 12/296:16 pmFSD - MDT
1 stop4h 51mUnited Airlines
Deal found 9/10$344
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:34 pmMDT - FSD
2 stops9h 22mDelta
Wed 12/315:00 amFSD - MDT
2 stops16h 51mDelta
Deal found 9/10$348
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:00 amMDT - FSD
2 stops8h 28mAmerican Airlines
Tue 12/306:45 amFSD - MDT
2 stops12h 36mAmerican Airlines
Deal found 9/10$349
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:15 amMDT - FSD
1 stop7h 22mUnited Airlines
Mon 9/2911:19 amFSD - MDT
1 stop4h 33mUnited Airlines
Deal found 9/10$369
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:30 amMDT - FSD
2 stops12h 26mUnited Airlines
Mon 12/297:30 amFSD - MDT
1 stop5h 38mUnited Airlines
Deal found 9/10$380
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:15 amMDT - FSD
2 stops12h 15mUnited Airlines
Thu 1/13:08 pmFSD - MDT
1 stop7h 59mUnited Airlines
Deal found 9/10$399

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Harrisburg to Sioux Falls that are best for you.

Fly from

Harrisburg

Fly to

Sioux Falls

Route

Depart

Return

Price

HarrisburgSioux Falls

MDT - FSD

MDTFSD

Harrisburg

Sat 10/11

6:51 am-12:42 pm

1 stop6h 51m

Sioux Falls Joe Foss Field

Sat 10/18

1:27 pm-11:13 pm

1 stop8h 46m

$259

HarrisburgSioux Falls

MDT - FSD

MDTFSD

Harrisburg

Sat 10/11

12:20 pm-7:19 pm

2 stops7h 59m

Sioux Falls Joe Foss Field

Sat 10/18

1:35 pm-11:08 pm

2 stops8h 33m

$349

HarrisburgSioux Falls

MDT - FSD

MDTFSD

Harrisburg

Thu 9/25

8:15 am-2:37 pm

1 stop7h 22m

Sioux Falls Joe Foss Field

Mon 9/29

11:19 am-4:52 pm

1 stop4h 33m

$369

HarrisburgSioux Falls

MDT - FSD

MDTFSD

Harrisburg

Fri 10/17

6:25 pm-10:56 pm

1 stop5h 31m

Sioux Falls Joe Foss Field

Sat 10/18

1:35 pm-11:08 pm

2 stops8h 33m

$614

HarrisburgSioux Falls

MDT - FSD

MDTFSD

Harrisburg

Mon 9/15

5:48 pm-10:12 pm

1 stop5h 24m

Sioux Falls Joe Foss Field

Thu 9/18

11:20 am-4:52 pm

1 stop4h 32m

$1,143

HarrisburgSioux Falls

MDT - FSD

MDTFSD

Harrisburg

Sat 10/11

9:12 pm-8:27 am

1 stop12h 15m

$146

HarrisburgSioux Falls

MDT - FSD

MDTFSD

Harrisburg

Sat 10/11

12:20 pm-7:19 pm

2 stops7h 59m

$276

HarrisburgSioux Falls

MDT - FSD

MDTFSD

Harrisburg

Fri 10/17

6:25 pm-10:56 pm

1 stop5h 31m

$400

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Harrisburg to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Sioux Falls

What is the cheapest month to book a flight from Harrisburg to Sioux Falls?

Currently, September is the cheapest month in which you can book a flight from Harrisburg to Sioux Falls (average of $334). Flying from Harrisburg to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to Sioux Falls?

Reviews of airlines servicing Sioux Falls

Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated September 11, 2025.
See what other customers who have flown with United Airlines and American Airlines from Harrisburg to Sioux Falls have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Sioux Falls?

    There are many flights that can get you from Harrisburg to Sioux Falls in 6h 51m. Fly via American Airlines or Delta to get the fastest option. Airlines will cover a distance of 1050 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to Sioux Falls round-trip?

    Flying on United Airlines is currently your cheapest option to Sioux Falls, with prices starting at $293. Another option worth looking into is American Airlines, starting at $358 round trip. United Airlines is 45% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Harrisburg to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Sioux Falls.

  • Can I find deals for business class flights from Harrisburg to Sioux Falls?

    Yes. Cheapflights offers flight deals from Harrisburg to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Sioux Falls?

    Currently, September is the cheapest month in which you can book a flight from Harrisburg to Sioux Falls (average of $334). Flying from Harrisburg to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall

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Alternative routes for Harrisburg to Sioux Falls

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Harrisburg to Sioux Falls

Discover the top 2 airlines that operate flights from Harrisburg to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$293Average$693FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$358Average$488FlexibilityNo cancel feeOn-time71%

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