$149+ Cheap flights from Columbus to Santiago de los Caballeros (STI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — STI
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to Santiago de los Caballeros with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Santiago de los Caballeros
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Cheapest flights from Columbus to Santiago de los CaballerosExplore the most affordable flight options available from Columbus to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Columbus to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
CMH
- STI
1 stop8h 02m
Multiple Airlines
Sun 5/33:07 pm
STI
- CMH
2 stops19h 58m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
CMH
- STI
1 stop8h 12m
Multiple Airlines
Mon 5/184:15 pm
STI
- CMH
2 stops24h 55m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:07 am
CMH
- STI
1 stop17h 52m
Delta
Wed 6/108:59 pm
STI
- CMH
1 stop14h 54m
Delta
Deal found 4/6![Delta logo]()
$540
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:10 am
CMH
- STI
2 stops11h 01m
Delta
Tue 9/228:40 pm
STI
- CMH
1 stop15h 01m
Delta
Deal found 4/7![Delta logo]()
$545
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:13 pm
CMH
- STI
1 stop20h 25m
American Airlines
Tue 6/163:38 pm
STI
- CMH
1 stop9h 07m
American Airlines
Deal found 4/7![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:18 pm
CMH
- STI
2 stops16h 02m
American Airlines
Tue 10/131:40 pm
STI
- CMH
2 stops10h 13m
American Airlines
Deal found 4/6![American Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:46 pm
CMH
- STI
1 stop18h 35m
American Airlines
Mon 6/157:03 am
STI
- CMH
1 stop17h 42m
American Airlines
Deal found 4/7![American Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:52 pm
CMH
- STI
2 stops21h 31m
American Airlines
Sun 5/311:21 pm
STI
- CMH
2 stops10h 31m
American Airlines
Deal found 4/6![American Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:00 am
CMH
- STI
2 stops15h 13m
American Airlines
Mon 6/157:03 am
STI
- CMH
1 stop17h 42m
American Airlines
Deal found 4/7![American Airlines logo]()
$573
Best flights from Columbus to Santiago de los CaballerosDiscover carefully curated flight deals from Columbus to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Columbus to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
CMH
- STI
1 stop8h 12m
Multiple Airlines
Mon 5/184:15 pm
STI
- CMH
2 stops24h 55m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:07 am
CMH
- STI
1 stop17h 52m
Delta
Wed 6/108:59 pm
STI
- CMH
1 stop14h 54m
Delta
Deal found 4/6![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:52 pm
CMH
- STI
2 stops21h 31m
American Airlines
Sun 5/311:21 pm
STI
- CMH
2 stops10h 31m
American Airlines
Deal found 4/4![American Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:44 pm
CMH
- STI
1 stop12h 15m
Delta
Sun 5/318:59 pm
STI
- CMH
1 stop14h 57m
Delta
Deal found 4/8![Delta logo]()
$580
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:37 pm
CMH
- STI
1 stop17h 46m
Delta
Mon 5/181:50 pm
STI
- CMH
1 stop9h 23m
Delta
Deal found 4/5![Delta logo]()
$580
Last-minute flights from Columbus to Santiago de los CaballerosDiscover last-minute flight deals from Columbus to Santiago de los Caballeros. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Santiago de los Caballeros. Data last updated April 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
CMH
- STI
1 stop8h 02m
Multiple Airlines
Sun 5/33:07 pm
STI
- CMH
2 stops19h 58m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
CMH
- STI
1 stop8h 12m
Multiple Airlines
Mon 5/184:15 pm
STI
- CMH
2 stops24h 55m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:57 pm
CMH
- STI
2 stops21h 26m
American Airlines
Mon 5/181:32 pm
STI
- CMH
2 stops19h 48m
American Airlines
Deal found 4/5![American Airlines logo]()
$577
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:37 pm
CMH
- STI
1 stop17h 46m
Delta
Mon 5/181:50 pm
STI
- CMH
1 stop9h 23m
Delta
Deal found 4/5![Delta logo]()
$580
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:52 pm
CMH
- STI
2 stops21h 31m
American Airlines
Sun 5/311:21 pm
STI
- CMH
2 stops10h 31m
American Airlines
Deal found 4/6![American Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:46 pm
CMH
- STI
1 stop18h 35m
American Airlines
Wed 6/39:06 am
STI
- CMH
1 stop13h 31m
American Airlines
Deal found 4/8![American Airlines logo]()
$619
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:00 am
CMH
- STI
2 stops11h 13m
American Airlines
Sun 5/311:21 pm
STI
- CMH
1 stop8h 38m
American Airlines
Deal found 4/7![American Airlines logo]()
$629
One-way flights from Columbus to Santiago de los CaballerosSearch for one-way flight options from Columbus to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Columbus to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Priceline deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
CMH
- STI
1 stop8h 02m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$149
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
CMH
- STI
1 stop8h 02m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:05 pm
CMH
- STI
2 stops21h 15m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:05 pm
CMH
- STI
2 stops21h 15m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:44 pm
CMH
- STI
2 stops47h 36m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:00 pm
CMH
- STI
2 stops19h 02m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
CMH
- STI
1 stop9h 20m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:37 pm
CMH
- STI
2 stops24h 35m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:05 pm
CMH
- STI
2 stops21h 15m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$283
Find flight deals from Columbus to Santiago de los Caballeros
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 9, 2026.
Round-trip from | $440 (Kiwi.com) |
|---|---|
One-way from | $149 (Priceline) |
Popular in | June |
Cheapest in | April |
Average price | $428 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Columbus to Santiago de los Caballeros that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Sat 5/9
6:00 am-2:12 pm
1 stop8h 12m
Santiago de los Caballeros
Mon 5/18
4:15 pm-5:10 pm
2 stops24h 55m
$507
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Tue 6/2
7:07 am-12:59 am
1 stop17h 52m
Santiago de los Caballeros
Wed 6/10
8:59 pm-11:53 am
1 stop14h 54m
$540
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Sat 5/16
2:52 pm-12:23 pm
2 stops21h 31m
Santiago de los Caballeros
Sun 5/31
1:21 pm-11:52 pm
2 stops10h 31m
$570
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Wed 5/20
12:44 pm-12:59 am
1 stop12h 15m
Santiago de los Caballeros
Sun 5/31
8:59 pm-11:56 am
1 stop14h 57m
$580
Quickest round-trip
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Sat 5/9
6:37 pm-12:23 pm
1 stop17h 46m
Santiago de los Caballeros
Mon 5/18
1:50 pm-11:13 pm
1 stop9h 23m
$580
Cheapest one-way
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Sun 5/17
6:05 pm-3:20 pm
2 stops21h 15m
$216
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Sun 4/19
7:00 pm-2:02 pm
2 stops19h 02m
$254
Quickest one-way
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Fri 5/22
6:00 am-3:20 pm
1 stop9h 20m
$282
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Tue 5/26
6:25 am-12:59 am
2 stops18h 34m
$318
ColumbusSantiago de los Caballeros
CMH - STI
CMHSTI
Columbus
Wed 5/20
12:44 pm-12:59 am
1 stop12h 15m
$318
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Columbus to Santiago de los Caballeros
Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Columbus with our price prediction graph.
C01-STI
CMH-STI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to Santiago de los Caballeros
C01-STI
CMH-STI
What is the cheapest month to book a flight from Columbus to Santiago de los Caballeros?
Currently, March is the cheapest month in which you can book a flight from Columbus to Santiago de los Caballeros (average of $261). Flying from Columbus to Santiago de los Caballeros in June is currently the most expensive (average of $432). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Columbus to Santiago de los Caballeros?
Reviews of airlines servicing Santiago de los Caballeros
Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated April 9, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Columbus to Santiago de los Caballeros. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Santiago de los Caballeros flight routes
Alternative routes for Columbus to Santiago de los Caballeros
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago de los Caballeros by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to Santiago de los Caballeros by cabin class
Find flights from Columbus to Santiago de los Caballeros, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and Santiago de los Caballeros flights
Browse other Columbus and Santiago de los Caballeros flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago de los Caballeros
Explore flights to Santiago de los Caballeros departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 9, 2026.
Top 4 airlines flying from Columbus to Santiago de los Caballeros
Discover the top 4 airlines that operate flights from Columbus to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$391 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$472 | Average$563 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$488 | Average$548 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$490 | Average$531 | FlexibilityNo cancel fee | On-time69% |