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$89+ Cheap flights from Sao Paulo, Brazil (SAO) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAO — SCL
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Sao Paulo to Santiago Arturo Merino Benitez are usually found in October or March, booked 30 days in advance, depart on a Monday or Wednesday and return on a Friday

Cheap flight deals from Sao Paulo to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Sao Paulo (SAO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$196
(Booking.com)

One-way from

$89
(Booking.com)

Popular in

July

Cheapest in

October

Average price

$224

Good round-trip deal

$245 or less

Good one-way deal

$109 or less
From Sao Paulo (SAO) to Santiago Arturo Merino Benitez
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One-way flight from Sao Paulo (SAO) to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 7% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Sao Paulo (SAO) to Santiago Arturo Merino Benitez.
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Price to beat on a one-way flight from Sao Paulo (SAO) to Santiago Arturo Merino Benitez.
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Find flight deals from Sao Paulo to Santiago

Cheapest flights from Sao Paulo to Santiago
Explore the most affordable flight options available from Sao Paulo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:15 pmGRU - SCL
Nonstop4h 20mSky Airline
Sat 11/292:15 pmSCL - GRU
Nonstop4h 00mSky Airline
Deal found 9/15$196
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:15 pmGRU - SCL
Nonstop4h 20mSky Airline
Sat 11/152:15 pmSCL - GRU
Nonstop4h 00mSky Airline
Deal found 9/14$201
This Sky Airline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:15 pmGRU - SCL
Nonstop4h 20mSky Airline
Fri 11/142:15 pmSCL - GRU
Nonstop4h 00mSky Airline
Deal found 9/14$205
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/67:15 pmGRU - SCL
Nonstop4h 25mSky Airline
Mon 10/132:30 pmSCL - GRU
Nonstop3h 45mSky Airline
Deal found 9/14$206
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/283:20 amGRU - SCL
Nonstop4h 25mSky Airline
Fri 10/32:30 pmSCL - GRU
Nonstop3h 45mSky Airline
Deal found 9/15$210
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:15 pmGRU - SCL
Nonstop4h 25mSky Airline
Mon 10/62:30 pmSCL - GRU
Nonstop3h 45mSky Airline
Deal found 9/15$215
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2910:00 amGRU - SCL
Nonstop4h 30mMultiple Airlines
Fri 10/32:30 pmSCL - GRU
Nonstop3h 45mMultiple Airlines
Deal found 9/15$216
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:30 pmGRU - SCL
Nonstop4h 20mLATAM Airlines
Tue 10/216:30 pmSCL - GRU
Nonstop3h 55mLATAM Airlines
Deal found 9/15$217
This SmartFares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:45 amGRU - SCL
Nonstop4h 10mTurkish Airlines
Thu 11/611:40 amSCL - GRU
Nonstop3h 55mTurkish Airlines
Deal found 9/15$218
This Sky Airline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:15 pmGRU - SCL
Nonstop4h 25mSky Airline
Mon 10/62:30 pmSCL - GRU
Nonstop3h 45mSky Airline
Deal found 9/15$219
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/157:15 pmGRU - SCL
Nonstop4h 25mMultiple Airlines
Sat 9/204:37 amSCL - GRU
Nonstop3h 58mMultiple Airlines
Deal found 9/14$220
This Sky Airline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:15 pmGRU - SCL
Nonstop4h 25mSky Airline
Fri 10/312:15 pmSCL - GRU
Nonstop4h 00mSky Airline
Deal found 9/15$223

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sao Paulo to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Sao Paulo to Santiago that are best for you.

Fly from

Sao Paulo

Fly to

Santiago

Route

Depart

Return

Price

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Fri 10/24

7:15 pm-11:40 pm

Nonstop4h 25m

Santiago Arturo Merino Benitez

Mon 11/3

2:15 pm-6:15 pm

Nonstop4h 00m

$205

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Sat 10/18

3:40 am-8:05 am

Nonstop4h 25m

Santiago Arturo Merino Benitez

Fri 10/31

2:15 pm-6:15 pm

Nonstop4h 00m

$205

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Fri 10/17

7:15 pm-11:40 pm

Nonstop4h 25m

Santiago Arturo Merino Benitez

Sat 10/25

2:30 pm-6:15 pm

Nonstop3h 45m

$205

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Sun 11/23

7:15 pm-11:35 pm

Nonstop4h 20m

Santiago Arturo Merino Benitez

Sat 11/29

2:15 pm-6:15 pm

Nonstop4h 00m

$205

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Sat 10/11

4:30 pm-8:50 pm

Nonstop4h 20m

Santiago Arturo Merino Benitez

Tue 10/21

6:30 pm-10:25 pm

Nonstop3h 55m

$217

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Tue 10/7

7:15 pm-11:40 pm

Nonstop4h 25m

Santiago Arturo Merino Benitez

Mon 10/13

2:30 pm-6:15 pm

Nonstop3h 45m

$219

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Tue 10/21

7:15 pm-11:40 pm

Nonstop4h 25m

Santiago Arturo Merino Benitez

Mon 10/27

2:15 pm-6:15 pm

Nonstop4h 00m

$219

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Fri 10/3

7:15 pm-11:40 pm

Nonstop4h 25m

Santiago Arturo Merino Benitez

Mon 10/6

2:30 pm-6:15 pm

Nonstop3h 45m

$219

Sao PauloSantiago

GRU - SCL

GRUSCL

Sao Paulo Guarulhos Intl

Sat 11/1

7:15 pm-11:35 pm

Nonstop4h 20m

Santiago Arturo Merino Benitez

Fri 11/7

2:15 pm-6:15 pm

Nonstop4h 00m

$223

Sao PauloSantiago

VCP - SCL

VCPSCL

Sao Paulo Viracopos

Mon 10/6

5:55 pm-9:00 pm

2 stops27h 05m

Santiago Arturo Merino Benitez

Sat 10/25

9:50 pm-9:00 am

2 stops11h 10m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 52 results
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Best time to book a flight from Sao Paulo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Sao Paulo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sao Paulo to Santiago

How far ahead should I book a flight from Sao Paulo to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Sao Paulo to Santiago. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Sao Paulo to Santiago, you should look to book at least 30 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Sao Paulo to Santiago?

Currently, April is the cheapest month in which you can book a flight from Sao Paulo to Santiago (average of $752). Flying from Sao Paulo to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAO to SCL?

Find hourly flight availability from Sao Paulo to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Sao Paulo to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 54% versus a flight in the afternoon.

What is the cheapest day to fly from Sao Paulo to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Sao Paulo to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Sao Paulo to Santiago flight should consider departing on Monday mornings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Sao Paulo to Santiago

Explore weekly flight availability from Sao Paulo to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from SAO to SCL are scheduled on a Monday (32 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (16 on average).

How much does it cost to fly round-trip from Sao Paulo to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 15, 2025.
See what other customers who have flown with LATAM Airlines and JetSMART from Sao Paulo to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,847 reviews

Comfort

7.4

Overall

7.5

Food

6.7

Boarding

7.6

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.
LATAM Airlines
7.5
Good
1,847 reviews
LATAM Airlines
7.5
Good
1,847 reviews

Comfort

7.4

Overall

7.5

Food

6.7

Boarding

7.6

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.
JetSMART
6.5
Okay
225 reviews
LATAM Airlines
7.5
Good
1,847 reviews

Comfort

7.4

Overall

7.5

Food

6.7

Boarding

7.6

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.

Related info for your journey

Find useful and relevant information for your journey from Sao Paulo to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Sao Paulo?

    Most people fly into Santiago Arturo Merino Benitez (SCL) if they book a flight to Santiago from Sao Paulo. On average, Arturo Merino Benitez has 24 inbound flights from Sao Paulo per day from 4 airlines. Santiago Arturo Merino Benitez is conveniently located just 8.4 mi from Santiago’s city center.

  • How long is the flight from Sao Paulo to Santiago?

    A quick flight from Sao Paulo to Santiago can take about 4h 25m. Sky Airline provides one of the quickest options available for as low as $205. Sao Paulo and Santiago are separated by a distance of 1623 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Sao Paulo to Santiago round-trip?

    Cheapflights users have booked flights from Sao Paulo to Santiago round-trip from $97. Other airlines that can offer you cheap pricing are JetSMART, from $126, and LATAM Airlines, from $151. Sky Airline is priced at 55% lower than the current average price of a flight leaving 3 months from now.

  • What are the most popular routes from Sao Paulo to Santiago?

    While some choose either Sao Paulo Guarulhos Intl - Santiago Arturo Merino Benitez or Sao Paulo Viracopos - Santiago Arturo Merino Benitez, Sao Paulo Congonhas - Santiago Arturo Merino Benitez is the most popular route from Sao Paulo to Santiago.

  • What are the most reliable airlines from Sao Paulo to Santiago?

    No one likes to see their flight delayed. When booking a flight from Sao Paulo to Santiago consider choosing British Airways (89%), JetSMART (83%) or Delta (83%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Sao Paulo to Santiago?

    The cheapest flight price from Sao Paulo to Santiago is $59. On average you can expect to pay $235. The most popular route, (Sao Paulo Congonhas - Santiago Arturo Merino Benitez), can usually be booked for $400.

  • Can I find deals for flights from Sao Paulo to Santiago that include hotel bookings?

    Yes. In addition to deals on Sao Paulo to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sao Paulo to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sao Paulo to Santiago.

  • Can I find deals for business class flights from Sao Paulo to Santiago?

    Yes. Cheapflights offers flight deals from Sao Paulo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sao Paulo to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Sao Paulo to Santiago (average of $752). Flying from Sao Paulo to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Sao Paulo to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Guarulhos Intl to Santiago flights

Top 4 airlines flying from Sao Paulo to Santiago

Discover the top 4 airlines that operate flights from Sao Paulo to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Sky AirlineCheapest$97Average$202FlexibilityNo cancel feeOn-time73%
JetSMARTCheapest$126Average$219FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$151Average$247FlexibilityNo cancel feeOn-time81%
Turkish AirlinesCheapest$154Average$255FlexibilityNo cancel feeOn-time77%

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