Santiago

$201+ Cheap flights from Jose Maria Cordova Intl (MDE) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
MDE — SCL
Oct 11 — Oct 181
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Cheapflights Tip: The best prices from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez are usually found in October or November, booked 84 days in advance, depart on a Tuesday or Monday and return on a Sunday

Cheap flight deals from Jose Maria Cordova Intl to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Jose Maria Cordova Intl (MDE) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$343
(OneTravel)

One-way from

$201
(CheapOair)

Popular in

July

Cheapest in

October

Average price

$369

Good round-trip deal

$353 or less
From Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez
One-way flight from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez
Highest demand for flights based on searches. 2% potential increase in price ($10 potential increase over avg. RT price).
Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
Average for round-trip flights in September 2025
Price to beat on a round-trip flight from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez.

Find flight deals from Jose Maria Cordova Intl to Santiago

Cheapest flights from Jose Maria Cordova Intl to Santiago
Explore the most affordable flight options available from Jose Maria Cordova Intl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This OneTravel deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:13 pmMDE - SCL
Nonstop6h 08mJetSMART
Thu 2/199:29 pmSCL - MDE
1 stop21h 20mJetSMART
Deal found 9/11$343
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:14 pmMDE - SCL
1 stop11h 03mJetSMART
Mon 10/275:59 amSCL - MDE
1 stop12h 50mJetSMART
Deal found 9/10$346
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:30 amMDE - SCL
1 stop12h 51mJetSMART
Thu 2/199:29 pmSCL - MDE
1 stop14h 15mJetSMART
Deal found 9/11$361
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:00 pmMDE - SCL
Nonstop6h 08mJetSMART
Thu 2/199:29 pmSCL - MDE
1 stop21h 20mJetSMART
Deal found 9/11$362
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:00 pmMDE - SCL
Nonstop6h 08mJetSMART
Tue 2/173:37 pmSCL - MDE
1 stop10h 16mJetSMART
Deal found 9/11$363
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:13 pmMDE - SCL
Nonstop6h 08mJetSMART
Wed 12/248:58 amSCL - MDE
Nonstop6h 15mJetSMART
Deal found 9/11$364
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:13 pmMDE - SCL
Nonstop6h 08mJetSMART
Tue 2/173:37 pmSCL - MDE
1 stop10h 16mJetSMART
Deal found 9/11$373
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:13 pmMDE - SCL
Nonstop6h 08mJetSMART
Fri 2/209:29 pmSCL - MDE
1 stop21h 20mJetSMART
Deal found 9/11$374
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:14 pmMDE - SCL
1 stop11h 03mMultiple Airlines
Mon 10/278:50 pmSCL - MDE
2 stops11h 45mMultiple Airlines
Deal found 9/10$378

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jose Maria Cordova Intl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to Santiago that are best for you.

Fly from

Jose Maria Cordova Intl

Fly to

Santiago

Route

Depart

Return

Price

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 12/11

5:00 pm-1:08 am

Nonstop6h 08m

Santiago Arturo Merino Benitez

Wed 2/18

7:49 am-12:13 pm

Nonstop6h 24m

$387

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Wed 11/12

5:59 pm-4:30 am

1 stop8h 31m

Santiago Arturo Merino Benitez

Wed 11/19

6:40 am-4:15 pm

1 stop11h 35m

$392

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Wed 10/1

10:46 am-11:40 pm

1 stop10h 54m

Santiago Arturo Merino Benitez

Tue 10/7

12:29 pm-8:14 pm

1 stop9h 45m

$395

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Tue 9/30

7:58 pm-2:45 pm

2 stops16h 47m

Santiago Arturo Merino Benitez

Tue 10/14

3:30 pm-10:26 pm

1 stop8h 56m

$395

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Fri 11/21

10:46 am-11:41 pm

1 stop10h 55m

Santiago Arturo Merino Benitez

Fri 11/28

3:23 am-2:45 pm

1 stop13h 22m

$395

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Mon 11/17

3:15 pm-3:24 am

1 stop10h 09m

Santiago Arturo Merino Benitez

Thu 11/20

12:20 pm-8:00 pm

1 stop9h 40m

$395

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Fri 11/14

9:44 am-3:43 am

1 stop15h 59m

Santiago Arturo Merino Benitez

Sat 11/22

1:29 am-4:59 pm

1 stop17h 30m

$395

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Wed 11/5

6:24 am-12:06 am

1 stop15h 42m

Santiago Arturo Merino Benitez

Sat 11/15

5:12 am-8:16 pm

1 stop17h 04m

$395

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 11/6

6:24 am-8:21 pm

1 stop11h 57m

Santiago Arturo Merino Benitez

Tue 11/18

1:29 am-9:51 am

1 stop10h 22m

$395

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Wed 11/5

6:24 am-11:41 pm

1 stop15h 17m

Santiago Arturo Merino Benitez

Sat 11/8

1:29 am-2:15 pm

1 stop14h 46m

$395

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 20 results
1
2

Best time to book a flight from Jose Maria Cordova Intl to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Jose Maria Cordova Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medellín Jose Maria Cordova Intl Airport to Santiago

How far ahead should I book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Jose Maria Cordova Intl to Santiago. Price data was last updated on August 29, 2025.

Booking 84 days in advance of your planned departure date is, on average, the best time to get cheap flights from Medellín Jose Maria Cordova Intl Airport to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

Currently, April is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago (average of $752). Flying from Medellín Jose Maria Cordova Intl Airport to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDE to SCL?

Find hourly flight availability from Jose Maria Cordova Intl to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 22% on flights from Medellín Jose Maria Cordova Intl Airport to Santiago by exploring options for tickets in the morning.

How much does it cost to fly round-trip from Medellín Jose Maria Cordova Intl Airport to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Copa Airlines, LATAM Airlines, and Avianca from Medellín Jose Maria Cordova Intl Airport to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.1

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Crew

8.1

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Crew

8.1

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Crew

8.1

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Crew

8.1

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Jose Maria Cordova Intl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santiago from Medellín Jose Maria Cordova Intl?

    Santiago Arturo Merino Benitez (SCL) is the airport you will fly into if you book a flight from Medellín Jose Maria Cordova Intl to Santiago. You should not have trouble finding flights to Arturo Merino Benitez from Medellín Jose Maria Cordova Intl; the airport handles an average of 0 inbound flights from Medellín Jose Maria Cordova Intl per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Santiago airport from Medellín Jose Maria Cordova Intl. It is only a 8.4 mi journey from Arturo Merino Benitez (SCL) to Santiago’s city center.

  • How long is the flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    For as low as $387, JetSMART can have you in Santiago from Medellín Jose Maria Cordova Intl Airport in 6h 08m. Medellín Jose Maria Cordova Intl Airport and Santiago are separated by a distance of 2748 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Medellín Jose Maria Cordova Intl Airport to Santiago round-trip?

    Currently priced at $177, JetSMART will fly you from Medellín Jose Maria Cordova Intl Airport to Santiago and back. In addition to JetSMART, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from LATAM Airlines and Copa Airlines - these airlines can fly you to your destination from $256 and $336, respectively. These flights start at 53% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Medellín Jose Maria Cordova Intl Airport to Santiago one-way?

    For one-way options, check prices for JetSMART. According to our data, you can fly for as low as $232. Users have also found prices from $237 and $238 on LATAM Airlines and Copa Airlines, respectively.

  • What are the cheapest flights from Medellín Jose Maria Cordova Intl Airport to Santiago?

    Looking at all options, your cheapest flight can be booked for $353. While the most popular route (Medellín Jose Maria Cordova Intl - Santiago Arturo Merino Benitez) can be booked for $368 on average, our data indicates $365 when flying from Medellín Jose Maria Cordova Intl Airport to Santiago.

  • Can I find deals for flights from Jose Maria Cordova Intl to Santiago that include hotel bookings?

    Yes. In addition to deals on Jose Maria Cordova Intl to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jose Maria Cordova Intl to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jose Maria Cordova Intl to Santiago.

  • Can I find deals for business class flights from Jose Maria Cordova Intl to Santiago?

    Yes. Cheapflights offers flight deals from Jose Maria Cordova Intl to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago (average of $752). Flying from Medellín Jose Maria Cordova Intl Airport to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.

Top 4 airlines flying from Jose Maria Cordova Intl to Santiago

Discover the top 4 airlines that operate flights from Jose Maria Cordova Intl to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetSMARTCheapest$177Average$386FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$256Average$429FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$336Average$441FlexibilityNo cancel feeOn-time70%
AviancaCheapest$354Average$481FlexibilityNo cancel feeOn-time71%

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