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$218+ Cheap flights from Jose Maria Cordova Intl (MDE) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
MDE — SCL
Jan 13 — Jan 201
Tue 1/13
Tue 1/20
1 adult, Economy
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Cheapflights Tip: The best prices from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez are usually found in March or May, booked 70 days in advance, depart on a Tuesday or Wednesday and return on a Sunday

Cheap flight deals from Jose Maria Cordova Intl to Santiago

Cheapest flights from Jose Maria Cordova Intl to Santiago
Explore the most affordable flight options available from Jose Maria Cordova Intl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

This JetSMART deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:01 pmMDE - SCL
Nonstop6h 08mJetSMART
Sun 8/2312:58 amSCL - MDE
Nonstop6h 24mJetSMART
Deal found 12/14$406
This LATAM Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:15 pmMDE - SCL
1 stop8h 15mLATAM Airlines
Wed 1/285:15 amSCL - MDE
1 stop13h 00mLATAM Airlines
Deal found 12/13$413
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:00 amMDE - SCL
1 stop13h 21mCopa Airlines
Tue 12/305:12 amSCL - MDE
1 stop11h 33mCopa Airlines
Deal found 12/13$424
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1410:46 amMDE - SCL
1 stop17h 15mCopa Airlines
Wed 12/315:44 amSCL - MDE
1 stop16h 16mCopa Airlines
Deal found 12/13$440
This Copa Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:17 amMDE - SCL
1 stop16h 26mCopa Airlines
Thu 1/15:20 amSCL - MDE
1 stop13h 39mCopa Airlines
Deal found 12/12$462
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:15 pmMDE - SCL
1 stop12h 46mCopa Airlines
Thu 1/15:20 amSCL - MDE
1 stop13h 39mCopa Airlines
Deal found 12/13$479
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:00 amMDE - SCL
1 stop13h 21mCopa Airlines
Sun 12/285:12 amSCL - MDE
1 stop11h 33mCopa Airlines
Deal found 12/13$489
This Copa Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:46 amMDE - SCL
1 stop11h 38mCopa Airlines
Sun 12/285:12 amSCL - MDE
1 stop11h 33mCopa Airlines
Deal found 12/14$505

Find flight deals from Jose Maria Cordova Intl to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Jose Maria Cordova Intl (MDE) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 14, 2025.

Most accurate provider

OneTravel
3 stars

Most trusted provider

OneTravel
3 stars

Round-trip from

$313
(Booking.com)

One-way from

$207
(JetSMART)

Popular in

July

Cheapest in

March

Average price

$388

Good round-trip deal

$297 or less

Good one-way deal

$235 or less
Provider with most accurate pricing for Medellín Jose Maria Cordova Intl-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Medellín Jose Maria Cordova Intl-Santiago Arturo Merino Benitez flights.
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From Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez
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One-way flight from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 1% potential increase in price ($6 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez.
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Price to beat on a one-way flight from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Jose Maria Cordova Intl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to Santiago that are best for you.

Fly from

Jose Maria Cordova Intl

Fly to

Santiago

Route

Depart

Return

Price

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 5/21

5:01 pm-12:09 am

Nonstop6h 08m

Santiago Arturo Merino Benitez

Sun 5/24

12:59 am-6:23 am

Nonstop6h 24m

$320

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Sun 4/5

5:01 pm-12:09 am

Nonstop6h 08m

Santiago Arturo Merino Benitez

Thu 4/9

12:59 am-6:23 am

Nonstop6h 24m

$333

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Mon 3/23

5:01 pm-1:09 am

Nonstop6h 08m

Santiago Arturo Merino Benitez

Thu 3/26

1:59 am-6:14 am

Nonstop6h 15m

$355

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Fri 5/1

5:01 pm-12:09 am

Nonstop6h 08m

Santiago Arturo Merino Benitez

Sun 5/17

3:33 pm-1:00 pm

1 stop22h 27m

$383

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 3/12

5:01 pm-1:09 am

Nonstop6h 08m

Santiago Arturo Merino Benitez

Sun 3/15

1:59 am-6:14 am

Nonstop6h 15m

$387

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Fri 3/27

5:01 pm-1:09 am

Nonstop6h 08m

Santiago Arturo Merino Benitez

Fri 4/3

1:59 am-6:23 am

Nonstop6h 24m

$394

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Sun 4/19

6:15 pm-4:50 am

1 stop9h 35m

Santiago Arturo Merino Benitez

Thu 4/30

11:25 pm-9:20 am

1 stop10h 55m

$399

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Wed 3/11

1:08 pm-9:27 am

1 stop18h 19m

Santiago Arturo Merino Benitez

Sun 3/15

1:59 am-6:14 am

Nonstop6h 15m

$399

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 3/5

6:27 am-8:01 pm

2 stops35h 34m

Santiago Arturo Merino Benitez

Tue 3/24

1:59 am-6:14 am

Nonstop6h 15m

$407

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 12/25

5:01 pm-1:09 am

Nonstop6h 08m

$218

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 16 results
1
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Compare providers for flights from Jose Maria Cordova Intl to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jose Maria Cordova Intl to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars
OneTravelPrice Accuracy3 starsTrust Score*3 stars
CheapOairPrice Accuracy3 starsTrust Score*3 stars
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medellín Jose Maria Cordova Intl Airport-Santiago flights, users find the pricing of OneTravel to be most consistent on Cheapflights vs. OneTravel Users can find the same prices on Medellín Jose Maria Cordova Intl Airport-Santiago flight deals on Cheapflights vs. OneTravel >95% of the time. Price accuracy is based on data collected from Medellín Jose Maria Cordova Intl Airport-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medellín Jose Maria Cordova Intl Airport-Santiago flights, Cheapflights users trust OneTravel the most. OneTravel has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medellín Jose Maria Cordova Intl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jose Maria Cordova Intl to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Jose Maria Cordova Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medellín Jose Maria Cordova Intl Airport to Santiago

How far ahead should I book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Jose Maria Cordova Intl to Santiago. Price data was last updated on December 12, 2025.

Booking 66 days in advance of your planned departure date is, on average, the best time to get cheap flights from Medellín Jose Maria Cordova Intl Airport to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

Currently, February is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago (average of $161). Flying from Medellín Jose Maria Cordova Intl Airport to Santiago in July is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDE to SCL?

Find hourly flight availability from Jose Maria Cordova Intl to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 14, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 62% on flights from Medellín Jose Maria Cordova Intl Airport to Santiago by exploring options for tickets in the morning.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 14, 2025.
Get a feel of what it's like to fly with Copa Airlines, LATAM Airlines, and Avianca from Medellín Jose Maria Cordova Intl Airport to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,557 reviews

Overall

7.6

Food

6.8

Crew

8.1

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,557 reviews
Copa Airlines
7.6
Good
1,557 reviews

Overall

7.6

Food

6.8

Crew

8.1

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,891 reviews
Copa Airlines
7.6
Good
1,557 reviews

Overall

7.6

Food

6.8

Crew

8.1

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,485 reviews
Copa Airlines
7.6
Good
1,557 reviews

Overall

7.6

Food

6.8

Crew

8.1

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
JetSMART
6.6
Okay
252 reviews
Copa Airlines
7.6
Good
1,557 reviews

Overall

7.6

Food

6.8

Crew

8.1

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Jose Maria Cordova Intl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Medellín Jose Maria Cordova Intl?

    Santiago Arturo Merino Benitez (SCL) is the airport you will fly into if you book a flight from Medellín Jose Maria Cordova Intl to Santiago. You should not have trouble finding flights to Arturo Merino Benitez from Medellín Jose Maria Cordova Intl; the airport handles an average of 0 inbound flights from Medellín Jose Maria Cordova Intl per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Santiago airport from Medellín Jose Maria Cordova Intl. It is only a 8.4 mi journey from Arturo Merino Benitez (SCL) to Santiago’s city center.

  • How long is the flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    For as low as $320, JetSMART can have you in Santiago from Medellín Jose Maria Cordova Intl Airport in 6h 08m. Medellín Jose Maria Cordova Intl Airport and Santiago are separated by a distance of 2748 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from Medellín Jose Maria Cordova Intl Airport to Santiago round-trip?

    Currently priced at $155, JetSMART will fly you from Medellín Jose Maria Cordova Intl Airport to Santiago and back. In addition to JetSMART, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Copa Airlines and LATAM Airlines - these airlines can fly you to your destination from $240 and $385, respectively. These flights start at 60% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Medellín Jose Maria Cordova Intl Airport to Santiago one-way?

    For one-way options, check prices for JetSMART. According to our data, you can fly for as low as $167. Users have also found prices from $212 and $228 on Copa Airlines and LATAM Airlines, respectively.

  • What are the cheapest flights from Medellín Jose Maria Cordova Intl Airport to Santiago?

    Looking at all options, your cheapest flight can be booked for $168. While the most popular route (Medellín Jose Maria Cordova Intl - Santiago Arturo Merino Benitez) can be booked for $374 on average, our data indicates $314 when flying from Medellín Jose Maria Cordova Intl Airport to Santiago.

  • Can I find deals for flights from Jose Maria Cordova Intl to Santiago that include hotel bookings?

    Yes. In addition to deals on Jose Maria Cordova Intl to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jose Maria Cordova Intl to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jose Maria Cordova Intl to Santiago.

  • Can I find deals for business class flights from Jose Maria Cordova Intl to Santiago?

    Yes. Cheapflights offers flight deals from Jose Maria Cordova Intl to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    Currently, February is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago (average of $161). Flying from Medellín Jose Maria Cordova Intl Airport to Santiago in July is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Top 4 airlines flying from Jose Maria Cordova Intl to Santiago

Discover the top 4 airlines that operate flights from Jose Maria Cordova Intl to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetSMARTCheapest$168Average$380FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$240Average$441FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$385Average$469FlexibilityNo cancel feeOn-time81%
AviancaCheapest$389Average$461FlexibilityNo cancel feeOn-time71%

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