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$244+ Cheap flights from Detroit Metropolitan Wayne County Airport to Santa Fe (DTW - SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SAF
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Detroit to Santa Fe

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santa Fe (SAF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$264
(American Airlines)

One-way from

$244
(United Airlines)

Popular in

October

Cheapest in

July

Average price

$496
From Detroit Metropolitan Wayne County to Santa Fe
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One-way flight from Detroit Metropolitan Wayne County to Santa Fe
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Highest demand for flights based on searches. 10% potential increase in price ($63 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Detroit to Santa Fe

Cheapest flights from Detroit to Santa Fe
Explore the most affordable flight options available from Detroit to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:11 amDTW - SAF
1 stop6h 17mAmerican Airlines
Tue 11/186:15 amSAF - DTW
1 stop6h 45mAmerican Airlines
Deal found 9/11$264
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/279:00 amDTW - SAF
1 stop5h 41mUnited Airlines
Sat 10/47:10 amSAF - DTW
1 stop5h 50mUnited Airlines
Deal found 9/10$289
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/144:09 pmDTW - SAF
1 stop6h 52mAmerican Airlines
Sat 10/186:15 amSAF - DTW
1 stop5h 50mAmerican Airlines
Deal found 9/11$314
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:09 pmDTW - SAF
1 stop7h 50mAmerican Airlines
Sat 10/186:15 amSAF - DTW
1 stop5h 50mAmerican Airlines
Deal found 9/10$315
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:33 amDTW - SAF
2 stops11h 19mAmerican Airlines
Sat 11/86:15 amSAF - DTW
1 stop6h 45mAmerican Airlines
Deal found 9/9$329
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:24 amDTW - SAF
1 stop9h 31mAmerican Airlines
Wed 12/109:58 amSAF - DTW
1 stop6h 41mAmerican Airlines
Deal found 9/9$344
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amDTW - SAF
2 stops8h 41mUnited Airlines
Sat 10/187:10 amSAF - DTW
1 stop5h 50mUnited Airlines
Deal found 9/10$355
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:06 pmDTW - SAF
1 stop6h 57mUnited Airlines
Sat 10/47:10 amSAF - DTW
1 stop5h 50mUnited Airlines
Deal found 9/10$369

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Fe that are best for you.

Fly from

Detroit

Fly to

Santa Fe

Route

Depart

Return

Price

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 9/27

2:45 pm-10:03 pm

2 stops9h 18m

Santa Fe

Sat 10/4

7:10 am-4:51 pm

2 stops7h 41m

$300

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 10/14

4:09 pm-9:01 pm

1 stop6h 52m

Santa Fe

Sat 10/18

6:15 am-2:05 pm

1 stop5h 50m

$314

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Mon 11/3

5:33 am-2:52 pm

2 stops11h 19m

Santa Fe

Sat 11/8

6:15 am-3:00 pm

1 stop6h 45m

$329

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 12/6

5:11 am-9:26 am

1 stop6h 15m

Santa Fe

Wed 12/10

9:58 am-6:39 pm

1 stop6h 41m

$344

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 9/30

9:00 am-12:41 pm

1 stop5h 41m

Santa Fe

Sat 10/4

1:23 pm-10:22 pm

1 stop6h 59m

$369

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Thu 9/25

5:06 pm-10:03 pm

1 stop6h 57m

Santa Fe

Sat 10/4

7:10 am-3:00 pm

1 stop5h 50m

$369

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 9/27

4:05 pm-9:56 pm

1 stop7h 51m

Santa Fe

Thu 10/2

10:03 am-6:30 pm

1 stop6h 27m

$369

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Thu 9/25

5:06 pm-10:03 pm

1 stop6h 57m

Santa Fe

Tue 10/7

1:23 pm-10:22 pm

1 stop6h 59m

$369

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Thu 9/25

5:35 pm-9:59 pm

1 stop6h 24m

Santa Fe

Wed 10/1

2:05 pm-10:40 pm

1 stop6h 35m

$369

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sun 9/28

9:00 am-12:41 pm

1 stop5h 41m

Santa Fe

Mon 10/6

7:10 am-3:00 pm

1 stop5h 50m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 14 results
1
2

Best time to book a flight from Detroit to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Santa Fe

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santa Fe?

Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santa Fe (average of $372). Flying from Detroit Metropolitan Wayne County Airport to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Detroit Metropolitan Wayne County Airport to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Crew

8.1

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Crew

8.1

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,937 reviews

Crew

8.1

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Santa Fe?

    United Airlines and American Airlines can get you from Detroit Metropolitan Wayne County Airport to Santa Fe in just under 6h 52m. Your travel time can differ by up to 2h 26m. Detroit Metropolitan Wayne County Airport and Santa Fe are separated by a distance of 1299 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Santa Fe round-trip?

    Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to Santa Fe round-trip from $349. Another airline that can offer you cheap pricing is American Airlines. United Airlines is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Detroit to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santa Fe.

  • Can I find deals for business class flights from Detroit to Santa Fe?

    Yes. Cheapflights offers flight deals from Detroit to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santa Fe?

    Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santa Fe (average of $372). Flying from Detroit Metropolitan Wayne County Airport to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Alternative routes for Detroit to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Detroit to Santa Fe

Discover the top 2 airlines that operate flights from Detroit to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$349Average$562FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$380Average$514FlexibilityNo cancel feeOn-time71%

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