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$244+ Cheap flights from Detroit Metropolitan Wayne County Airport to Santa Fe (DTW - SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SAF
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Detroit to Santa Fe

Cheapest flights from Detroit to Santa Fe
Explore the most affordable flight options available from Detroit to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:07 amDTW - SAF
1 stop5h 34mUnited Airlines
Sat 11/151:25 pmSAF - DTW
1 stop6h 52mUnited Airlines
Deal found 10/25$289
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:02 amDTW - SAF
2 stops10h 40mUnited Airlines
Sat 11/151:25 pmSAF - DTW
1 stop6h 52mUnited Airlines
Deal found 10/27$324
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/209:07 amDTW - SAF
1 stop5h 33mUnited Airlines
Thu 11/277:00 amSAF - DTW
1 stop5h 58mUnited Airlines
Deal found 10/27$346
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:30 pmDTW - SAF
1 stop7h 29mUnited Airlines
Mon 11/171:26 pmSAF - DTW
1 stop6h 51mUnited Airlines
Deal found 10/26$348
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:11 amDTW - SAF
1 stop6h 17mAmerican Airlines
Mon 11/176:15 amSAF - DTW
1 stop6h 45mAmerican Airlines
Deal found 10/26$349
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:11 amDTW - SAF
1 stop6h 17mAmerican Airlines
Tue 12/26:15 amSAF - DTW
1 stop6h 45mAmerican Airlines
Deal found 10/26$364
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:30 pmDTW - SAF
1 stop7h 29mUnited Airlines
Tue 11/181:25 pmSAF - DTW
1 stop6h 52mUnited Airlines
Deal found 10/26$369

Cheap flight deals from Detroit to Santa Fe

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santa Fe (SAF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$289
(United Airlines)

One-way from

$244
(American Airlines)

Popular in

October

Cheapest in

November

Average price

$620
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Santa Fe flight deals.
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Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Santa Fe flights.
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From Detroit Metropolitan Wayne County to Santa Fe
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Santa Fe
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High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Fe that are best for you.

Fly from

Detroit

Fly to

Santa Fe

Route

Depart

Return

Price

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 11/8

9:07 am-12:41 pm

1 stop5h 34m

Santa Fe

Sat 11/15

1:25 pm-10:17 pm

1 stop6h 52m

$289

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Wed 11/12

4:30 pm-9:59 pm

1 stop7h 29m

Santa Fe

Mon 11/17

1:26 pm-11:59 pm

2 stops8h 33m

$299

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 11/14

4:30 pm-9:59 pm

1 stop7h 29m

Santa Fe

Mon 11/17

10:48 am-11:59 pm

2 stops11h 11m

$299

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 11/11

7:15 am-12:41 pm

2 stops7h 26m

Santa Fe

Sat 11/15

1:25 pm-11:59 pm

2 stops8h 34m

$329

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 11/14

5:11 am-9:28 am

1 stop6h 17m

Santa Fe

Mon 11/17

6:15 am-3:00 pm

1 stop6h 45m

$349

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 11/14

5:11 am-9:28 am

1 stop6h 17m

Santa Fe

Tue 11/18

6:15 am-3:00 pm

1 stop6h 45m

$349

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Thu 11/20

5:45 am-12:40 pm

2 stops8h 55m

Santa Fe

Thu 11/27

7:00 am-2:58 pm

1 stop5h 58m

$356

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 11/14

4:30 pm-9:59 pm

1 stop7h 29m

Santa Fe

Tue 11/18

1:25 pm-10:17 pm

1 stop6h 52m

$369

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 3/31

5:18 am-11:07 am

1 stop7h 49m

$244

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 3/31

12:11 pm-10:01 pm

2 stops11h 50m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 12 results
1
2

Compare providers for flights from Detroit to Santa Fe

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Santa Fe in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santa Fe flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit Metropolitan Wayne County Airport-Santa Fe flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Santa Fe flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santa Fe flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Santa Fe flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Santa Fe

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santa Fe?

Currently, February is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santa Fe (average of $203). Flying from Detroit Metropolitan Wayne County Airport to Santa Fe in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated October 28, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Detroit Metropolitan Wayne County Airport to Santa Fe. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,001 reviews

Overall

7.4

Food

6.6

Entertainment

7.1

Comfort

7.3

Crew

8.1

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,001 reviews
United Airlines
7.4
Good
9,001 reviews

Overall

7.4

Food

6.6

Entertainment

7.1

Comfort

7.3

Crew

8.1

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,032 reviews
United Airlines
7.4
Good
9,001 reviews

Overall

7.4

Food

6.6

Entertainment

7.1

Comfort

7.3

Crew

8.1

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Santa Fe?

    United Airlines can get you from Detroit Metropolitan Wayne County Airport to Santa Fe in just under 5h 34m. Your travel time can differ by up to . Detroit Metropolitan Wayne County Airport and Santa Fe are separated by a distance of 1299 mi.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Santa Fe round-trip?

    Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to Santa Fe round-trip from $344. Another airline that can offer you cheap pricing is United Airlines. American Airlines is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Detroit to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santa Fe.

  • Can I find deals for business class flights from Detroit to Santa Fe?

    Yes. Cheapflights offers flight deals from Detroit to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santa Fe?

    Currently, February is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santa Fe (average of $203). Flying from Detroit Metropolitan Wayne County Airport to Santa Fe in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Alternative routes for Detroit to Santa Fe

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Top 2 airlines flying from Detroit to Santa Fe

Discover the top 2 airlines that operate flights from Detroit to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$344Average$493FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$349Average$572FlexibilityNo cancel feeOn-time69%

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