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Santa Cruz de la Sierra

$487+ Cheap flights from Madrid, Spain (MAD) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — VVI
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheapflights Tip: The best prices from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl are usually found in May or March, booked 55 days in advance, depart on a Wednesday or Friday and return on a Wednesday

Cheap flight deals from Madrid to Santa Cruz de la Sierra

Cheapest flights from Madrid to Santa Cruz de la Sierra
Explore the most affordable flight options available from Madrid to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Avianca deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:20 amMAD - VVI
1 stop30h 15mAvianca
Sat 1/243:40 amVVI - MAD
1 stop24h 10mAvianca
Deal found 12/16$1,741
This CheapOair deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:55 pmMAD - VVI
2 stops24h 55mMultiple Airlines
Sat 1/315:25 amVVI - MAD
1 stop19h 15mMultiple Airlines
Deal found 12/17$2,098
This Avianca deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:35 amMAD - VVI
1 stop25h 00mAvianca
Fri 1/303:40 amVVI - MAD
1 stop19h 55mAvianca
Deal found 12/16$2,120
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2111:35 pmMAD - VVI
Nonstop11h 20mAir Europa
Sat 1/311:30 pmVVI - MAD
Nonstop10h 40mAir Europa
Deal found 12/16$2,288

Find flight deals from Madrid to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$932
(FlightHub)

One-way from

$487
(FlightHub)

Popular in

December

Cheapest in

May

Average price

$1,444
Provider with most accurate pricing for Madrid Barajas-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Madrid Barajas-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Madrid to Santa Cruz de la Sierra that are best for you.

Fly from

Madrid

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 2/3

12:40 am-4:35 am

1 stop32h 55m

Santa Cruz de la Sierra Viru Viru Intl

Wed 3/4

5:25 am-5:40 am

1 stop19h 15m

$954

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Thu 3/19

1:20 am-2:35 am

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/20

2:55 am-2:05 pm

1 stop29h 10m

$965

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 1/25

1:20 am-2:35 am

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/9

3:40 am-1:25 pm

1 stop28h 45m

$1,040

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 4/29

11:25 am-1:50 am

2 stops20h 25m

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/19

2:55 am-7:40 am

1 stop22h 45m

$1,058

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sat 3/21

7:05 am-2:35 am

2 stops24h 30m

Santa Cruz de la Sierra Viru Viru Intl

Wed 4/15

2:55 am-7:40 am

1 stop22h 45m

$1,058

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 5/10

7:05 am-1:50 am

2 stops24h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/23

2:55 am-11:10 am

1 stop26h 15m

$1,058

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 4/13

9:40 am-1:50 am

1 stop22h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

2:55 am-1:55 pm

2 stops29h 00m

$1,062

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 2/10

7:05 am-2:35 am

2 stops24h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

3:40 am-1:25 pm

1 stop28h 45m

$1,091

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 4/13

1:10 pm-1:50 am

1 stop18h 40m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/9

2:55 am-1:55 pm

2 stops29h 00m

$1,094

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 4/27

1:30 am-1:50 am

1 stop30h 20m

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/19

2:55 am-1:55 pm

2 stops29h 00m

$1,113

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 21 results
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Compare providers for flights from Madrid to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madrid to Santa Cruz de la Sierra in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Madrid-Santa Cruz de la Sierra flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Madrid-Santa Cruz de la Sierra flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Madrid-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Madrid-Santa Cruz de la Sierra flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Madrid to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santa Cruz de la Sierra

How far ahead should I book a flight from Madrid to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santa Cruz de la Sierra. Price data was last updated on December 12, 2025.

The best time to book flights from Madrid to Santa Cruz de la Sierra is 55 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Madrid to Santa Cruz de la Sierra?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santa Cruz de la Sierra (average of $613). Flying from Madrid to Santa Cruz de la Sierra in July is currently the most expensive (average of $958). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to VVI?

Find hourly flight availability from Madrid to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Madrid to Santa Cruz de la Sierra as you normally would.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Madrid to Santa Cruz de la Sierra, such as Air Europa, BoA, and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Air Europa
7.0
Good
572 reviews

Entertainment

6.6

Crew

7.5

Food

6.3

Comfort

6.9

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.
Air Europa
7.0
Good
572 reviews
Air Europa
7.0
Good
572 reviews

Entertainment

6.6

Crew

7.5

Food

6.3

Comfort

6.9

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.
BoA
6.6
Okay
137 reviews
Air Europa
7.0
Good
572 reviews

Entertainment

6.6

Crew

7.5

Food

6.3

Comfort

6.9

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.
Avianca
6.6
Okay
2,490 reviews
Air Europa
7.0
Good
572 reviews

Entertainment

6.6

Crew

7.5

Food

6.3

Comfort

6.9

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Santa Cruz de la Sierra?

    If you wish to fly to Santa Cruz de la Sierra from Madrid, then you need to book flights from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl. There is 1 flight from Barajas (MAD) to Viru Viru Intl (VVI) per day to choose from. Flights to Santa Cruz de la Sierra from Barajas are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 11h 00m is how long a nonstop flight from Madrid to Santa Cruz de la Sierra Viru Viru Intl typically takes.

  • How popular is this Madrid to Santa Cruz de la Sierra flight route?

    The Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Santa Cruz de la Sierra?

    There are many flights that can get you from Madrid to Santa Cruz de la Sierra in 30h 15m. Fly via LATAM Airlines or Avianca to get the fastest option. There are 5537 mi between Madrid and Santa Cruz de la Sierra. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Madrid to Santa Cruz de la Sierra round-trip?

    Avianca, at $720, was found to be the cheapest airline from Madrid to Santa Cruz de la Sierra.Alternate airlines to your destination round-trip include Air Europa and BoA. Avianca is 33% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Madrid to Santa Cruz de la Sierra one-way?

    The cheapest airline one-way is BoA, with whom users have recently found tickets for as low as $272. However, be on the lookout for offers from Iberia and Air Europa, as they are both options that can get you from Madrid to Santa Cruz de la Sierra for a low price.

  • What are the most reliable airlines from Madrid to Santa Cruz de la Sierra?

    The top 3 most reliable airlines when flying from Madrid to Santa Cruz de la Sierra are Air Europa (56%), BoA (14%) and Iberia (14%).

  • What are the cheapest flights from Madrid to Santa Cruz de la Sierra?

    Looking at all options, your cheapest flight can be booked for $447. While the most popular route (Madrid Barajas - Santa Cruz de la Sierra Viru Viru Intl) can be booked for $948 on average, our data indicates $481 when flying from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for flights from Madrid to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Madrid to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Madrid to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Madrid to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santa Cruz de la Sierra?

    Currently, May is the cheapest month in which you can book a flight from Madrid to Santa Cruz de la Sierra (average of $613). Flying from Madrid to Santa Cruz de la Sierra in July is currently the most expensive (average of $958). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Madrid to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Madrid to La Paz flights

Top 3 airlines flying from Madrid to Santa Cruz de la Sierra

Discover the top 3 airlines that operate flights from Madrid to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$720Average$846FlexibilityNo cancel feeOn-time71%
Air EuropaCheapest$858Average$1,019FlexibilityNo cancel feeOn-time83%
BoACheapest$870Average$1,197FlexibilityNo cancel feeOn-timeN/A

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