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Santa Cruz de la Sierra

$495+ Cheap flights from Madrid, Spain (MAD) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/22. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — VVI
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheapflights Tip: The best prices from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl are usually found in May or March, booked 80 days in advance, depart on a Friday or Tuesday and return on a Wednesday

Find flight deals from Madrid to Santa Cruz de la Sierra

Cheapest flights from Madrid to Santa Cruz de la Sierra
Explore the most affordable flight options available from Madrid to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:50 amMAD - VVI
1 stop20h 45mAvianca
Fri 11/283:40 amVVI - MAD
1 stop14h 40mAvianca
Deal found 10/28$1,083
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:50 amMAD - VVI
1 stop20h 45mAvianca
Mon 11/173:40 amVVI - MAD
1 stop14h 40mAvianca
Deal found 10/29$1,111
This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:50 amMAD - VVI
1 stop20h 45mAvianca
Sat 1/243:40 amVVI - MAD
1 stop14h 40mAvianca
Deal found 10/30$1,114
This Gotogate deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:00 amMAD - VVI
2 stops24h 35mMultiple Airlines
Tue 11/189:50 pmVVI - MAD
2 stops57h 55mMultiple Airlines
Deal found 10/29$1,125
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/511:00 amMAD - VVI
2 stops26h 30mMultiple Airlines
Wed 11/263:05 pmVVI - MAD
2 stops40h 40mMultiple Airlines
Deal found 10/28$1,145
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:20 amMAD - VVI
1 stop30h 15mAvianca
Tue 3/243:40 amVVI - MAD
1 stop19h 55mAvianca
Deal found 10/29$1,152
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:05 amMAD - VVI
2 stops24h 30mAvianca
Wed 12/33:40 amVVI - MAD
1 stop24h 10mAvianca
Deal found 10/28$1,172

Cheap flight deals from Madrid to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$1,004
(CheapOair)

One-way from

$495
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$1,026
Provider with most accurate pricing for Madrid Barajas-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Madrid Barajas-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Madrid to Santa Cruz de la Sierra that are best for you.

Fly from

Madrid

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 2/9

1:20 am-2:35 am

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

3:40 am-8:50 am

1 stop24h 10m

$1,111

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 3/10

1:20 am-2:35 am

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Sun 5/10

2:55 am-7:40 am

1 stop22h 45m

$1,111

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sat 2/7

6:40 am-2:35 am

1 stop24h 55m

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/16

3:40 am-8:50 am

1 stop24h 10m

$1,111

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 3/8

10:50 am-2:35 am

1 stop20h 45m

Santa Cruz de la Sierra Viru Viru Intl

Wed 5/13

2:55 am-2:05 pm

1 stop29h 10m

$1,111

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 4/26

1:10 pm-1:50 am

1 stop18h 40m

Santa Cruz de la Sierra Viru Viru Intl

Wed 5/13

2:55 am-2:05 pm

1 stop29h 10m

$1,111

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Thu 12/25

10:50 am-2:35 am

1 stop20h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/24

3:40 am-11:20 pm

1 stop14h 40m

$1,114

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 11/14

10:50 am-2:35 am

1 stop20h 45m

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/17

3:40 am-1:25 pm

1 stop28h 45m

$1,121

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 12/31

1:20 am-2:35 am

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

3:40 am-4:35 am

1 stop19h 55m

$1,152

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 11/23

1:35 pm-11:05 am

1 stop26h 30m

$538

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 2/18

10:50 am-2:35 am

1 stop20h 45m

$587

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 18 results
1
2

Compare providers for flights from Madrid to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madrid to Santa Cruz de la Sierra in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Madrid-Santa Cruz de la Sierra flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Madrid-Santa Cruz de la Sierra flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Madrid-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Madrid-Santa Cruz de la Sierra flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Madrid to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santa Cruz de la Sierra

How far ahead should I book a flight from Madrid to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santa Cruz de la Sierra. Price data was last updated on October 24, 2025.

The best time to book flights from Madrid to Santa Cruz de la Sierra is 80 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Madrid to Santa Cruz de la Sierra?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santa Cruz de la Sierra (average of $649). Flying from Madrid to Santa Cruz de la Sierra in December is currently the most expensive (average of $916). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to VVI?

Find hourly flight availability from Madrid to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Madrid to Santa Cruz de la Sierra as you normally would.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Madrid to Santa Cruz de la Sierra, such as Air Europa, Iberia, and BoA. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Air Europa
7.0
Good
568 reviews

Food

6.3

Comfort

7.0

Entertainment

6.6

Crew

7.5

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.
Air Europa
7.0
Good
568 reviews
Air Europa
7.0
Good
568 reviews

Food

6.3

Comfort

7.0

Entertainment

6.6

Crew

7.5

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.
Iberia
7.0
Good
3,004 reviews
Air Europa
7.0
Good
568 reviews

Food

6.3

Comfort

7.0

Entertainment

6.6

Crew

7.5

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.
BoA
6.7
Okay
137 reviews
Air Europa
7.0
Good
568 reviews

Food

6.3

Comfort

7.0

Entertainment

6.6

Crew

7.5

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.
Avianca
6.6
Okay
2,467 reviews
Air Europa
7.0
Good
568 reviews

Food

6.3

Comfort

7.0

Entertainment

6.6

Crew

7.5

Overall

7.0

Boarding

7.1

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Madrid to Santa Cruz de la Sierra flight route?

    The Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Santa Cruz de la Sierra?

    There are many flights that can get you from Madrid to Santa Cruz de la Sierra in 30h 15m. Fly via Avianca to get the fastest option. There are 5537 mi between Madrid and Santa Cruz de la Sierra.

  • What are the cheapest airlines flying from Madrid to Santa Cruz de la Sierra round-trip?

    Avianca, at $720, was found to be the cheapest airline from Madrid to Santa Cruz de la Sierra.Alternate airlines to your destination round-trip include Iberia and Air Europa. Avianca is 31% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the most reliable airlines from Madrid to Santa Cruz de la Sierra?

    The top 3 most reliable airlines when flying from Madrid to Santa Cruz de la Sierra are BoA (72%), Iberia (72%) and Air Europa (63%).

  • What are the cheapest flights from Madrid to Santa Cruz de la Sierra?

    Looking at all options, your cheapest flight can be booked for $525. While the most popular route (Madrid Barajas - Santa Cruz de la Sierra Viru Viru Intl) can be booked for $994 on average, our data indicates $736 when flying from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for flights from Madrid to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Madrid to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Madrid to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Madrid to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santa Cruz de la Sierra?

    Currently, May is the cheapest month in which you can book a flight from Madrid to Santa Cruz de la Sierra (average of $649). Flying from Madrid to Santa Cruz de la Sierra in December is currently the most expensive (average of $916). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Madrid to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Madrid to La Paz flights

Top 4 airlines flying from Madrid to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Madrid to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$720Average$803FlexibilityNo cancel feeOn-time71%
IberiaCheapest$831Average$1,175FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$858Average$980FlexibilityNo cancel feeOn-time83%
BoACheapest$938Average$1,207FlexibilityNo cancel feeOn-timeN/A

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