Santa Cruz de la Sierra

$471+ Cheap flights from Madrid, Spain (MAD) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — VVI
Aug 4 — Aug 111
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Madrid to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl are usually found in May or March, booked 68 days in advance, depart on a Friday or Saturday and return on a Tuesday

Cheap flight deals from Madrid to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$910
(CheapOair)

One-way from

$471
(SmartFares)

Popular in

August

Cheapest in

May

Average price

$1,271
From Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl
One-way flight from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl
Highest demand for flights based on searches. 14% potential increase in price ($176 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($36 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Madrid to Santa Cruz de la Sierra

Cheapest flights from Madrid to Santa Cruz de la Sierra
Explore the most affordable flight options available from Madrid to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1812:40 amMAD - VVI
1 stop32h 55mLATAM Airlines
Sat 11/295:25 amVVI - MAD
1 stop30h 00mLATAM Airlines
Deal found 7/30$910
This Avianca deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/311:30 amMAD - VVI
1 stop30h 20mAvianca
Mon 9/152:50 amVVI - MAD
1 stop14h 40mAvianca
Deal found 7/29$926
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/711:35 pmMAD - VVI
Nonstop11h 15mAir Europa
Sat 9/2012:20 pmVVI - MAD
Nonstop10h 50mAir Europa
Deal found 7/29$972
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/181:20 amMAD - VVI
1 stop30h 15mMultiple Airlines
Sat 11/291:30 pmVVI - MAD
Nonstop10h 40mMultiple Airlines
Deal found 7/30$997
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2211:15 amMAD - VVI
2 stops41h 02mUnited Airlines
Tue 10/281:09 amVVI - MAD
2 stops49h 56mUnited Airlines
Deal found 7/30$1,077

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Madrid to Santa Cruz de la Sierra that are best for you.

Fly from

Madrid

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 11/18

12:40 am-4:35 am

1 stop32h 55m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/29

5:25 am-4:25 pm

1 stop30h 00m

$910

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 8/31

1:30 am-1:50 am

1 stop30h 20m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/15

2:50 am-11:30 pm

1 stop14h 40m

$926

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 9/7

11:35 pm-4:50 am

Nonstop11h 15m

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/20

12:20 pm-5:10 am

Nonstop10h 50m

$972

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 11/18

1:20 am-2:35 am

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/29

1:30 pm-5:10 am

Nonstop10h 40m

$997

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 10/22

11:15 am-10:17 pm

2 stops41h 02m

Santa Cruz de la Sierra Viru Viru Intl

Sun 10/26

1:09 am-8:05 am

2 stops49h 56m

$1,077

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 8/22

11:35 pm-4:50 am

Nonstop11h 15m

$471

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 10/26

1:20 am-2:35 am

1 stop30h 15m

$494

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 8/22

1:25 pm-1:50 am

3 stops42h 25m

$533

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 11/4

12:05 pm-4:35 am

2 stops21h 30m

$554

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 9/3

11:15 am-10:25 pm

2 stops41h 10m

$679

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 12 results
1
2

Best time to book a flight from Madrid to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santa Cruz de la Sierra

How far ahead should I book a flight from Madrid to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santa Cruz de la Sierra. Price data was last updated on July 25, 2025.

The best time to book flights from Madrid to Santa Cruz de la Sierra is 68 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Madrid to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Madrid to Santa Cruz de la Sierra (average of $597). Flying from Madrid to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to VVI?

Find hourly flight availability from Madrid to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Madrid to Santa Cruz de la Sierra in the afternoon. If you’re flexible enough to do this you can expect to save up to 25% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated July 30, 2025.
Read through reviews of airlines operating flights from Madrid to Santa Cruz de la Sierra, such as LATAM Airlines, United Airlines, and Air Europa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Madrid to Santa Cruz de la Sierra flight route?

  • What are the cheapest airlines flying from Madrid to Santa Cruz de la Sierra round-trip?

    LATAM Airlines, at $910, was found to be the cheapest airline from Madrid to Santa Cruz de la Sierra.Alternate airlines to your destination round-trip include Avianca and Air Europa. LATAM Airlines is 12% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Madrid to Santa Cruz de la Sierra one-way?

    The cheapest airline one-way is Air Europa, with whom users have recently found tickets for as low as $471. However, be on the lookout for offers from Avianca and LATAM Airlines, as they are both options that can get you from Madrid to Santa Cruz de la Sierra for a low price.

  • What are the cheapest flights from Madrid to Santa Cruz de la Sierra?

    Looking at all options, your cheapest flight can be booked for $475. While the most popular route (Madrid Barajas - Santa Cruz de la Sierra Viru Viru Intl) can be booked for $1,001 on average our data indicates $984 when flying from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for flights from Madrid to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Madrid to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Madrid to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Madrid to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Madrid to Santa Cruz de la Sierra (average of $597). Flying from Madrid to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Madrid to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Madrid to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Madrid to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$716Average$882FlexibilityNo cancel feeOn-time71%
Air EuropaCheapest$754Average$874FlexibilityNo cancel feeOn-time83%
IberiaCheapest$799Average$1,222FlexibilityNo cancel feeOn-time77%
BoACheapest$938Average$1,207FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.