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Santa Cruz de la Sierra

$773+ Cheap flights from Denver (DEN) to Santa Cruz de la Sierra (VVI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — VVI
Jun 19 — Jun 261
Fri 6/19
Fri 6/26
1 adult, Economy
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Find cheap flights from Denver to Santa Cruz de la Sierra with Cheapflights

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Cheap flight deals from Denver to Santa Cruz de la Sierra

Cheapest flights from Denver to Santa Cruz de la Sierra
Explore the most affordable flight options available from Denver to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.

This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:20 pm
DEN
-
VVI
2 stops23h 18m
United Airlines
Tue 6/2311:47 am
VVI
-
DEN
2 stops23h 00m
United Airlines
Deal found 5/16$773
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:05 am
DEN
-
VVI
2 stops41h 26m
United Airlines
Tue 6/2311:47 am
VVI
-
DEN
2 stops37h 28m
United Airlines
Deal found 5/17$781
This KAYAK deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2011:50 pm
DEN
-
VVI
2 stops44h 00m
Copa Airlines
Mon 11/3011:44 am
VVI
-
DEN
2 stops23h 55m
Copa Airlines
Deal found 5/16$902
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:00 am
DEN
-
VVI
2 stops14h 50m
United Airlines
Thu 11/1211:44 am
VVI
-
DEN
2 stops25h 28m
United Airlines
Deal found 5/17$903
This Copa Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1810:42 pm
DEN
-
VVI
1 stop21h 58m
Copa Airlines
Sat 8/11:12 am
VVI
-
DEN
1 stop19h 08m
Copa Airlines
Deal found 5/16$941
This Trip.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:40 pm
DEN
-
VVI
2 stops24h 50m
Multiple Airlines
Mon 6/223:35 am
VVI
-
DEN
3 stops46h 41m
Multiple Airlines
Deal found 5/17$1,076
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:40 pm
DEN
-
VVI
1 stop27h 10m
Multiple Airlines
Tue 6/2311:47 am
VVI
-
DEN
2 stops22h 50m
Multiple Airlines
Deal found 5/16$1,180
This Expedia deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:25 pm
DEN
-
VVI
2 stops34h 10m
Multiple Airlines
Thu 11/263:40 am
VVI
-
DEN
2 stops43h 47m
Multiple Airlines
Deal found 5/17$1,258
This Trip.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:30 am
DEN
-
VVI
2 stops19h 20m
Multiple Airlines
Sun 8/1611:35 pm
VVI
-
DEN
2 stops30h 23m
Multiple Airlines
Deal found 5/18$1,286

Find flight deals from Denver to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 20, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$781
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$712
Provider with most accurate pricing for Denver Intl-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Denver Intl to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($250 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($59 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Denver to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Tue 6/16

8:05 am-3:31 am

2 stops41h 26m

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/23

11:47 am-11:15 pm

2 stops37h 28m

$781

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sun 11/8

5:00 am-3:44 am

2 stops19h 44m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/12

11:44 am-8:39 am

2 stops23h 55m

$903
Quickest round-trip

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sat 7/18

10:42 pm-10:40 pm

1 stop21h 58m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/1

1:12 am-6:20 pm

1 stop19h 08m

$941

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Tue 6/16

11:40 pm-3:50 am

1 stop26h 10m

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/23

11:47 am-8:37 am

2 stops22h 50m

$1,078

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sat 7/18

1:53 pm-10:40 pm

2 stops30h 47m

Santa Cruz de la Sierra Viru Viru Intl

Sun 8/2

11:35 pm-8:23 am

1 stop34h 48m

$1,288

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sat 7/4

6:10 pm-4:35 am

3 stops32h 25m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/15

3:35 am-10:35 am

3 stops33h 00m

$1,546

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/17

Sorted by cheapest first

Compare providers for flights from Denver to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santa Cruz de la Sierra in May.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Denver-Santa Cruz de la Sierra flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Denver-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santa Cruz de la Sierra

How much does it cost to fly round-trip from Denver to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated May 20, 2026.
Read through reviews of airlines operating flights from Denver to Santa Cruz de la Sierra, such as Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,579 reviews

Boarding

7.7

Food

6.8

Crew

8.1

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines
Copa Airlines
7.5
Good
1,579 reviews
Copa Airlines
7.5
Good
1,579 reviews

Boarding

7.7

Food

6.8

Crew

8.1

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines
United Airlines
7.4
Good
9,738 reviews
Copa Airlines
7.5
Good
1,579 reviews

Boarding

7.7

Food

6.8

Crew

8.1

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Related info for your journey

Find useful and relevant information for your journey from Denver to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Denver to Santa Cruz de la Sierra?

    Airlines like United Airlines and Copa Airlines fly from Denver to Santa Cruz de la Sierra in about 21h 58m. The time it takes to get you to your destination can typically vary by up to 19h 28m. There are 4786 mi between Denver and Santa Cruz de la Sierra. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Denver to Santa Cruz de la Sierra round-trip?

    Flying on United Airlines is currently your cheapest option to Santa Cruz de la Sierra, with prices starting at $309. Another option worth looking into is Copa Airlines, starting at $606 round trip. United Airlines is priced at 61% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Denver to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Denver to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Denver to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Denver to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
Santa Cruz de la Sierra car rentals
Santa Cruz de la Sierra Viru Viru Intl Airport car rentals
La Paz car rentals
Cochabamba car rentals

Top 2 airlines flying from Denver to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from Denver to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$309Average$692FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$606Average$781FlexibilityNo cancel feeOn-time70%

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