$303+ Cheap flights from Denver (DEN) to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — VVI
Sep 16 — Sep 231
Round-trip
1 adult, Economy
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Find cheap flights from Denver to Santa Cruz de la Sierra with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to Santa Cruz de la Sierra
Cheapest
Best
Last-minute
One-way
Cheapest flights from Denver to Santa Cruz de la SierraExplore the most affordable flight options available from Denver to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from Denver to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:10 pm -
2 stops29h 28m
Wed 11/1111:49 am -
2 stops36h 38m
Deal found 8/16![United Airlines logo]()
$663
This KAYAK deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:00 am -
2 stops20h 38m
Thu 9/171:12 am -
2 stops31h 35m
Deal found 8/12![Copa Airlines logo]()
$723
This United deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:02 pm -
2 stops33h 36m
Mon 11/23:40 am -
2 stops34h 42m
Deal found 8/14![Multiple Airlines logo]()
$790
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:59 pm -
2 stops25h 39m
Tue 11/311:49 am -
2 stops24h 13m
Deal found 8/15![United Airlines logo]()
$801
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:43 pm -
1 stop22h 01m
Mon 10/511:47 am -
2 stops22h 32m
Deal found 8/13![Multiple Airlines logo]()
$837
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:43 pm -
1 stop22h 01m
Sun 10/41:12 am -
1 stop18h 59m
Deal found 8/13![Copa Airlines logo]()
$921
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:40 pm -
1 stop26h 10m
Thu 8/2011:47 am -
2 stops46h 36m
Deal found 8/13![Multiple Airlines logo]()
$1,024
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:09 am -
2 stops19h 41m
Fri 9/188:35 am -
1 stop25h 44m
Deal found 8/12![Multiple Airlines logo]()
$1,040
Best flights from Denver to Santa Cruz de la SierraDiscover carefully curated flight deals from Denver to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from Denver to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:10 pm -
2 stops29h 28m
Wed 11/1111:49 am -
2 stops36h 38m
Deal found 8/16![United Airlines logo]()
$663
This KAYAK deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:00 am -
2 stops20h 38m
Thu 9/171:12 am -
2 stops31h 35m
Deal found 8/12![Copa Airlines logo]()
$723
This United deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:02 pm -
2 stops33h 36m
Mon 11/23:40 am -
2 stops34h 42m
Deal found 8/14![Multiple Airlines logo]()
$790
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:59 pm -
2 stops25h 39m
Tue 11/311:49 am -
2 stops24h 13m
Deal found 8/15![United Airlines logo]()
$801
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:43 pm -
1 stop22h 01m
Sun 10/41:12 am -
1 stop18h 59m
Deal found 8/13![Copa Airlines logo]()
$921
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:09 am -
2 stops19h 41m
Fri 9/188:35 am -
1 stop25h 44m
Deal found 8/12![Multiple Airlines logo]()
$1,040
This Copa Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:43 pm -
1 stop26h 55m
Sat 10/241:12 am -
1 stop18h 59m
Deal found 8/17![Copa Airlines logo]()
$1,104
Last-minute flights from Denver to Santa Cruz de la SierraDiscover last-minute flight deals from Denver to Santa Cruz de la Sierra. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Santa Cruz de la Sierra. Data last updated August 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:58 pm -
2 stops28h 37m
Mon 8/2411:47 am -
2 stops45h 00m
Deal found 8/13![United Airlines logo]()
$663
This oojo deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:15 pm -
3 stops43h 14m
Mon 8/245:25 am -
2 stops21h 11m
Deal found 8/17![LATAM Airlines logo]()
$1,923
This FlightHub deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:43 pm -
1 stop26h 52m
Sun 8/233:35 am -
2 stops40h 16m
Deal found 8/13![Multiple Airlines logo]()
$1,955
This Justfly.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:00 pm -
2 stops34h 30m
Sun 8/233:35 am -
2 stops40h 16m
Deal found 8/17![Avianca logo]()
$1,990
This KAYAK deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:00 am -
2 stops20h 38m
Thu 9/171:12 am -
2 stops31h 35m
Deal found 8/12![Copa Airlines logo]()
$723
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:09 am -
2 stops19h 41m
Fri 9/188:35 am -
1 stop25h 44m
Deal found 8/12![Multiple Airlines logo]()
$1,040
One-way flights from Denver to Santa Cruz de la SierraSearch for one-way flight options from Denver to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from Denver to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2710:43 pm -
1 stop26h 55m
Deal found 8/15![Copa Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/278:58 pm -
2 stops28h 40m
Deal found 8/15![United Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:53 pm -
3 stops34h 37m
Deal found 8/15![Multiple Airlines logo]()
$430
Find flight deals from Denver to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $663 (United Airlines) |
One-way from | $303 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Denver to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Sat 11/7
2:10 pm-10:38 pm
2 stops29h 28m
Santa Cruz de la Sierra Viru Viru Intl
Wed 11/11
11:49 am-9:27 pm
2 stops36h 38m
$663
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Fri 9/11
5:00 am-3:38 am
2 stops20h 38m
Santa Cruz de la Sierra Viru Viru Intl
Thu 9/17
1:12 am-6:47 am
2 stops31h 35m
$723
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Tue 10/13
4:02 pm-3:38 am
2 stops33h 36m
Santa Cruz de la Sierra Viru Viru Intl
Mon 11/2
3:40 am-11:22 am
2 stops34h 42m
$790
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Tue 10/13
11:59 pm-3:38 am
2 stops25h 39m
Santa Cruz de la Sierra Viru Viru Intl
Tue 11/3
11:49 am-9:02 am
2 stops24h 13m
$801
Quickest round-trip
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Thu 10/1
10:43 pm-10:44 pm
1 stop22h 01m
Santa Cruz de la Sierra Viru Viru Intl
Sun 10/4
1:12 am-6:11 pm
1 stop18h 59m
$921
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Fri 9/11
6:09 am-3:50 am
2 stops19h 41m
Santa Cruz de la Sierra Viru Viru Intl
Fri 9/18
8:35 am-8:19 am
1 stop25h 44m
$1,040
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Thu 10/8
10:43 pm-3:38 am
1 stop26h 55m
Santa Cruz de la Sierra Viru Viru Intl
Sat 10/24
1:12 am-6:11 pm
1 stop18h 59m
$1,104
Cheapest one-way
Quickest one-way
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Sun 9/27
10:43 pm-3:38 am
1 stop26h 55m
$303
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Sun 9/27
8:58 pm-3:38 am
2 stops28h 40m
$318
DenverSanta Cruz de la Sierra
DEN Denver Intl - VVI Santa Cruz de la Sierra Viru Viru Intl
DENVVI
Denver Intl
Sun 9/27
1:53 pm-2:30 am
3 stops34h 37m
$430
Sorted by cheapest first
Compare providers for flights from Denver to Santa Cruz de la Sierra
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santa Cruz de la Sierra in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Denver-Santa Cruz de la Sierra flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Denver-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Denver with our price prediction graph.
DEN-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated August 17, 2026.
Read through reviews of airlines operating flights from Denver to Santa Cruz de la Sierra, such as Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Comfort
7.4
Crew
8.1
Entertainment
6.8
Overall
7.6
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Boarding
7.8
Comfort
7.4
Crew
8.1
Entertainment
6.8
Overall
7.6
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Boarding
7.8
Comfort
7.4
Crew
8.1
Entertainment
6.8
Overall
7.6
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Denver to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to Santa Cruz de la Sierra by cabin class
Find flights from Denver to Santa Cruz de la Sierra, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Santa Cruz de la Sierra flights
Browse other Denver and Santa Cruz de la Sierra flight options. Last updated on August 17, 2026.
Other flights from Denver
Browse through other flights departing from Denver. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Denver to Santa Cruz de la Sierra
Discover the top 2 airlines that operate flights from Denver to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$317 | Average$667 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$606 | Average$781 | FlexibilityNo cancel fee | On-time70% |