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Santa Cruz de la Sierra

$711+ Cheap flights from Denver (DEN) to Santa Cruz de la Sierra (VVI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — VVI
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Denver to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$711
(United Airlines)

Popular in

December

Cheapest in

January

Average price

$776
From Denver Intl to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($150 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($68 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Denver to Santa Cruz de la Sierra

Best flights from Denver to Santa Cruz de la Sierra
Discover carefully curated flight deals from Denver to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/158:39 pmDEN - VVI
2 stops23h 11mUnited Airlines
Fri 2/201:15 amVVI - DEN
2 stops19h 45mUnited Airlines
Deal found 9/14$711
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/153:50 pmDEN - VVI
2 stops28h 00mUnited Airlines
Thu 2/191:15 amVVI - DEN
3 stops26h 43mUnited Airlines
Deal found 9/14$711
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/145:33 pmDEN - VVI
2 stops26h 17mUnited Airlines
Fri 2/201:15 amVVI - DEN
3 stops24h 29mUnited Airlines
Deal found 9/14$711
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1611:50 pmDEN - VVI
2 stops20h 00mUnited Airlines
Fri 2/201:15 amVVI - DEN
2 stops19h 38mUnited Airlines
Deal found 9/14$711
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/134:03 pmDEN - VVI
2 stops27h 47mUnited Airlines
Thu 2/191:15 amVVI - DEN
2 stops25h 12mUnited Airlines
Deal found 9/14$711
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1311:40 pmDEN - VVI
2 stops20h 10mUnited Airlines
Fri 2/201:15 amVVI - DEN
2 stops19h 45mUnited Airlines
Deal found 9/14$875
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1411:40 pmDEN - VVI
2 stops20h 10mUnited Airlines
Sat 2/211:15 amVVI - DEN
1 stop19h 01mUnited Airlines
Deal found 9/14$954
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1611:50 pmDEN - VVI
2 stops20h 00mUnited Airlines
Sat 2/211:15 amVVI - DEN
1 stop19h 01mUnited Airlines
Deal found 9/14$954

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Denver to Santa Cruz de la Sierra that are best for you.

Fly from

Denver

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sun 2/15

8:39 pm-10:50 pm

2 stops23h 11m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/20

1:15 am-6:00 pm

2 stops19h 45m

$711

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sun 2/15

3:50 pm-10:50 pm

2 stops28h 00m

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/19

1:15 am-12:58 am

3 stops26h 43m

$711

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sat 2/14

5:33 pm-10:50 pm

2 stops26h 17m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/20

1:15 am-10:44 pm

3 stops24h 29m

$711

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Mon 2/16

11:50 pm-10:50 pm

2 stops20h 00m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/20

1:15 am-5:53 pm

2 stops19h 38m

$711

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Fri 2/13

4:03 pm-10:50 pm

2 stops27h 47m

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/19

1:15 am-11:27 pm

2 stops25h 12m

$711

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Fri 2/13

11:40 pm-10:50 pm

2 stops20h 10m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/20

1:15 am-6:00 pm

2 stops19h 45m

$875

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sat 2/14

11:40 pm-10:50 pm

2 stops20h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/21

1:15 am-5:16 pm

1 stop19h 01m

$954

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Mon 2/16

11:50 pm-10:50 pm

2 stops20h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/21

1:15 am-5:16 pm

1 stop19h 01m

$954

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Denver to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from Denver to Santa Cruz de la Sierra, such as Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Food

6.8

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Food

6.8

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
8,929 reviews
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Food

6.8

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Denver to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Denver to Santa Cruz de la Sierra?

    Airlines like United Airlines fly from Denver to Santa Cruz de la Sierra in about 23h 11m. The time it takes to get you to your destination can typically vary by up to . There are 4786 mi between Denver and Santa Cruz de la Sierra.

  • What are the cheapest airlines flying from Denver to Santa Cruz de la Sierra round-trip?

    Flying on Copa Airlines is currently your cheapest option to Santa Cruz de la Sierra, with prices starting at $575. Another option worth looking into is United Airlines, starting at $596 round trip. Copa Airlines is priced at 36% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Denver to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Denver to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Denver to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Denver to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Denver to Santa Cruz de la Sierra (average of $597). Flying from Denver to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Denver to La Paz flights

Top 2 airlines flying from Denver to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from Denver to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$575Average$688FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$596Average$823FlexibilityNo cancel feeOn-time69%

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